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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Demo 50 mg Tablet is used to treat depression, anxiety, and agitation. It contains Amoxapine, a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for mental health and mood changes. This medicine helps improve mood and feelings.

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Whats That

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Composition :

AMOXAPINE-50MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Demo 50 mg Tablet

Demo 50 mg Tablet is a second-generation tricyclic dibenzoxazepine antidepressant. It is used in the treatment of depression along with anxiety and agitation. Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the person's feelings, thinking and how they act. Anxiety is a mental condition characterized by excessive fear or worry affecting an individual's daily activities. This medicine is mostly given when patients become intolerant to other antidepressants.

Demo 50 mg Tablet contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

Demo 50 mg Tablet may cause certain common side effects such as drowsiness, dry mouth, increased heart rate, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and sudden blood pressure lowering on standing up (orthostatic hypotension). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Take Demo 50 mg Tablet as prescribed by your doctor. Your doctor will decide the dose of the medicine based on the severity of the condition.

Avoid taking Demo 50 mg Tablet if you are allergic to it or any of its ingredients. Demo 50 mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOs). Let your doctor know about your entire medical history beforehand. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding before starting treatment with Demo 50 mg Tablet . Do not stop taking Demo 50 mg Tablet suddenly, as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Uses of Demo 50 mg Tablet

Demo 50 mg Tablet is used to treat depression. The detailed uses of Demo 50 mg Tablet are as follows:<br/>• Manages depressive disorders: Demo 50 mg Tablet helps relieve symptoms of depression and improves mood.<br/>• Supports mental balance: Demo 50 mg Tablet is used to restore levels of certain natural substances in the brain to maintain emotional stability.<br/>

Directions for Use

• Demo 50 mg Tablet can be taken with or without food as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Demo 50 mg Tablet as a whole with a glass of water.• Do not break, chew or crush Demo 50 mg Tablet .

Medicinal Benefits

Demo 50 mg Tablet contains Amoxapine which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better. Demo 50 mg Tablet helps treat depression when patients become intolerant to other medicines.

How Demo 50 mg Tablet Works

Demo 50 mg Tablet contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

Storage

• Store in a cool and dry place away from sunlight.• Keep Demo 50 mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Demo 50 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost Vitamin K with leafy greens (spinach, kale), broccoli, cauliflower, and cabbage.
  • Include iron-rich foods like lean red meat, legumes, fortified cereals, and dark leafy greens.
  • Stay hydrated by drinking plenty of water.
  • Add Vitamin C-rich foods (citrus fruits, bell peppers) to enhance iron absorption.
  • Limit excessive alcohol and blood-thinning foods like garlic and certain herbs.
  • Engage in gentle exercise like walking, swimming, or yoga.
  • Monitor injuries and apply pressure to wounds promptly.
  • Schedule regular medical checkups for routine blood tests.

What if I have taken an overdose of Demo 50 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Demo 50 mg Tablet may include change in consciousness, drowsiness, epileptic seizure (that will not stop), fatigue, high blood pressure, increased thirst, loss of consciousness, swelling of face, fingers, or lower legs, total body jerking, troubled breathing, and weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Demo 50 mg Tablet should be avoided if you are allergic to it or any of its ingredients. Demo 50 mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOIs). Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting treatment with Demo 50 mg Tablet . Let your doctor know if you have liver or kidney disease, asthma, seizures, Parkinson’s disease, and high blood pressure before starting treatment with this medicine, as it may cause serious side effects. It is advised not to stop taking Demo 50 mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Demo 50 mg Tablet:
Co-administration of Demo 50 mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Demo 50 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Demo 50 mg Tablet:
Taking Demo 50 mg Tablet with Panobinostat can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and Panobinostat, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Demo 50 mg Tablet:
Co-administration of Demo 50 mg Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
How does the drug interact with Demo 50 mg Tablet:
Taking Demo 50 mg Tablet with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Demo 50 mg Tablet:
The combined use of Demo 50 mg Tablet and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Demo 50 mg Tablet:
Taking Demo 50 mg Tablet and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Demo 50 mg Tablet:
Taking prasugrel together with Demo 50 mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Demo 50 mg Tablet:
Taking Demo 50 mg Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Demo 50 mg Tablet:
Coadministration of Demo 50 mg Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Demo 50 mg Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Demo 50 mg Tablet:
Taking Dasatinib together with Demo 50 mg Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to do regular exercise, which can help lower anxiety and improve your sleep and self-image.
  • Find humour in your daily life. Try to watch a comedy show to help relieve stress.
  • You can try increasing your mindfulness by including yoga, meditation, cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include your diet with whole grains, vegetables, and fruits which is a healthier option than eating many simple carbohydrates in processed foods.
  • Include herbs like turmeric, ginger, and chamomile in the meal. It can reduce inflammation caused due to anxiety disorder.
  • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT
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Alcohol

Unsafe

Alcohol should be avoided while on treatment with Demo 50 mg Tablet as it can affect you much more and may make you feel more depressed.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy inform your doctor before taking Demo 50 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before receiving Demo 50 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Demo 50 mg Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with Demo 50 mg Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Demo 50 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Demo 50 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Demo 50 mg Tablet is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Have a query?

FAQs

Demo 50 mg Tablet is used to treat Depression.

Demo 50 mg Tablet contains Amoxapine, which belongs to the tricyclic antidepressant class of medicine. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes.

It is always advised to take Demo 50 mg Tablet around the same time every day for better results. Do not take more than the prescribed dose.

No, it is advised not to stop taking Demo 50 mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.

Demo 50 mg Tablet may cause side effects such as drowsiness, dry mouth, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and orthostatic hypotension (sudden lowering of blood pressure on standing up ). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

It is not known how/if Demo 50 mg Tablet affects pregnancy or the newborn baby. Therefore, consult the doctor if you are pregnant, planning pregnancy or breastfeeding. Your doctor may prescribe this medicine if the benefits outweigh the risks.

Demo 50 mg Tablet may increase the risk of suicidal behaviour and thinking; hence, patients taking Demo 50 mg Tablet should be monitored for clinical worsening, suicidality, or unusual changes in behaviour. Demo 50 mg Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with Demo 50 mg Tablet . Alcohol should be avoided while on treatment with Demo 50 mg Tablet as it may cause increased drowsiness.

Country of origin

INDIA

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, RIICO, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - DEM0006

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