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compositionComposition:DACLATASVIR-60MG
prescription
Prescription Medicine
info
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Dacihep 60 mg Tablet is used to treat Hepatitis C virus infection. It contains Daclatasvir, which works by blocking the activity of the hepatitis C virus in the liver cells. This causes viral DNA termination and reduces the amount of hepatitis C virus in the body. Common side effects of Dacihep 60 mg Tablet include headache, fatigue, weakness, confusion, chest pain, nausea, diarrhoea, shortness of breath, dizziness and lightheadedness.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

DACLATASVIR-60MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Dacihep 60 mg Tablet

Dacihep 60 mg Tablet is a prescription medication used to treat chronic hepatitis C infection. Its primary medical purpose is to help clear the hepatitis C virus from your body, preventing long-term complications. This medicine is always prescribed in combination with other antiviral medications to ensure the treatment is effective.

You will typically take Dacihep 60 mg Tablet once daily, and it is crucial to take it consistently at the same time every day. You can take this medicine with or without food. To support your liver during treatment, it is highly recommended to make lifestyle adjustments such as avoiding alcohol and eating a balanced, nutrient-rich diet.

While taking Dacihep 60 mg Tablet , some people may experience mild side effects like headaches or feeling unusually tired. However, you must contact your healthcare provider immediately if you experience serious symptoms such as a very slow heart rate, severe dizziness, or signs of liver strain like yellowing of your skin or eyes.

Before you start taking this medicine, tell your healthcare provider about your complete medical history. Do not take this if you are currently taking certain medications, such as specific treatments for tuberculosis or seizures, as they can stop Dacihep 60 mg Tablet from working. It is also important to let your doctor know if you have ever had a hepatitis B infection, as this virus can sometimes become active again during treatment.

This medicine can interact with several other drugs, including herbal supplements like St. John's wort and certain heart rate medications. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your healthcare provider to discuss the safety of this treatment for your specific situation.

Uses of Dacihep 60 mg Tablet

Your doctor may prescribe Dacihep 60 mg Tablet to help manage the following condition:

  • Chronic Hepatitis C Infection: Dacihep 60 mg Tablet is used to treat long-term hepatitis C viral infections in adults. It works by stopping the virus from multiplying, which helps the body clear the infection and protects the liver from progressive damage.

Key Benefits

When used as directed with other antiviral medicines, Dacihep 60 mg Tablet may provide the following benefits:

  • Helps clear the infection: Dacihep 60 mg Tablet helps stop the hepatitis C virus from multiplying. Successful treatment can clear the virus from the blood and prevent it from continuing to harm the liver.
  • Helps prevent further liver damage: Once the virus is cleared, ongoing liver inflammation can decrease, and further liver scarring may be prevented.
Side effects of Dacihep 60 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Dacihep 60 mg Tablet can be taken with or without food as advised by your doctor.
  • It is usually taken once daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the tablet as a whole with a glass of water.
  • Do not break, crush or chew Dacihep 60 mg Tablet .

How Dacihep 60 mg Tablet Works

Dacihep 60 mg Tablet contains daclatasvir. It belongs to a class of medicines called direct-acting antivirals. It works by targeting and blocking a specific viral protein known as NS5A. The hepatitis C virus absolutely requires this protein to copy its genetic material and multiply within your liver cells. Because Dacihep 60 mg Tablet is always used in combination with other antiviral medicines, it acts as part of a multi-sided attack. While Dacihep 60 mg Tablet stops the virus from replicating, the accompanying medication works to disrupt a different stage of the viral lifecycle. Together, they effectively stop the virus from spreading, allowing your immune system to clear the infection.
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Alcohol

Consult your doctor

It is not known if Dacihep 60 mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking Dacihep 60 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are a nursing mother, inform your doctor before taking Dacihep 60 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Consult your doctor

It is not known if Dacihep 60 mg Tablet affects your ability to drive. Do not drive or operate heavy machinery if you are not alert.

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Liver

Caution

If you have a history of liver disease, inform your doctor before taking Dacihep 60 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before taking Dacihep 60 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Dacihep 60 mg Tablet is not recommended for use in children below 18 years of age, as efficacy and safety have not been established.

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Heart

Caution

Dacihep 60 mg Tablet should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Dacihep 60 mg Tablet .

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Geriatrics

Safe if prescribed

Dacihep 60 mg Tablet is generally considered safe when used under medical supervision in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Dacihep 60 mg Tablet

In case of an accidental overdose, seek immediate emergency medical attention. Do not wait for symptoms of toxicity to appear.

Diet & Lifestyle Advise

  • Avoid alcohol entirely: Alcohol puts extra strain on your liver and can speed up liver damage, making it harder for your liver to heal during your antiviral treatment.
  • Eat a liver-friendly diet: Focus on whole foods, including plenty of fresh vegetables, fruits, lean proteins, and whole grains, while limiting foods high in saturated fats and refined sugars.
  • Stay well-hydrated: Drink plenty of water throughout the day to help your kidneys filter waste and keep your body hydrated.
  • Prevent virus transmission: Remember that while you are undergoing treatment, you can still pass the virus to others. Avoid sharing personal items like toothbrushes, razors, or nail clippers, and practice safe sex.
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How Soon It Starts Working

The time required for Dacihep 60 mg Tablet to start to work: Dacihep 60 mg Tablet ideally shows its action within 2 hours after administration. The time for which the effects of Dacihep 60 mg Tablet last: The effect of Dacihep 60 mg Tablet lasts for 3 to 4 days.

What if you forget to take Dacihep 60 mg Tablet

If you miss a dose and remember it within 20 hours of your scheduled time, take it as soon as you remember. If more than 20 hours have passed since your missed dose, skip the missed dose and take your next dose at your regular scheduled time. Do not take a double dose to make up for a missed one.

Storage

• Store Dacihep 60 mg Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Take treatment consistently: Take Dacihep 60 mg Tablet according to the schedule prescribed by your doctor. Do not stop treatment or skip doses intentionally, as incomplete or inconsistent antiviral treatment may reduce the chance of successfully clearing the infection.
  • Check before starting new medicines: Tell your doctor or pharmacist about all prescription medicines, over-the-counter medicines, and herbal supplements you use, as some can significantly affect daclatasvir levels and reduce its effectiveness or increase side effects.
  • Be cautious with amiodarone: Tell your doctor if you take amiodarone for a heart rhythm problem. When used with certain daclatasvir-containing antiviral regimens, amiodarone has been associated with serious slowing of the heart rate.
  • Check for hepatitis B: Your doctor should assess you for current or previous hepatitis B infection before starting hepatitis C treatment because hepatitis B can become active again during or after treatment.
  • Follow the complete antiviral regimen: Daclatasvir is used with other antiviral medicines. Take all medicines in your prescribed hepatitis C regimen as directed and do not change the treatment plan on your own.
  • Kidney conditions: Tell your doctor if you have kidney disease or are receiving dialysis. Daclatasvir itself generally does not require dose adjustment for kidney impairment, but the suitability of your overall hepatitis C treatment regimen may depend on your kidney function and the other antiviral medicines you receive. 

Drug-Drug Interactions

verifiedApollotooltip
  • Amiodarone: Combining this heart drug with Dacihep 60 mg Tablet and other antivirals can lead to a severe, life-threatening drop in your heart rate.
  • Rifampin and Seizure Medications (such as phenytoin or carbamazepine): These medicines can significantly lower the levels of Dacihep 60 mg Tablet in your body, making your hepatitis C treatment much less effective.
  • St. John's Wort: This herbal supplement can speed up how your body breaks down Dacihep 60 mg Tablet , reducing its ability to clear the virus.
DaclatasvirPrimidone
Critical
DaclatasvirCarbamazepine
Critical

Drug-Drug Interactions

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DaclatasvirPrimidone
Critical
How does the drug interact with Dacihep 60 mg Tablet:
Coadministration of Dacihep 60 mg Tablet with primidone may decrease the blood levels of Dacihep 60 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Primidone and Dacihep 60 mg Tablet, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DaclatasvirCarbamazepine
Critical
How does the drug interact with Dacihep 60 mg Tablet:
When Dacihep 60 mg Tablet is taken with Carbamazepine, it may decrease the blood levels of Dacihep 60 mg Tablet, which may make Dacihep 60 mg Tablet less effective in treating your Hepatitis C.

How to manage the interaction:
Taking Dacihep 60 mg Tablet with Carbamazepine is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
DaclatasvirMorphine
Severe
How does the drug interact with Dacihep 60 mg Tablet:
When Dacihep 60 mg Tablet is taken with Morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Dacihep 60 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
DaclatasvirMifepristone
Severe
How does the drug interact with Dacihep 60 mg Tablet:
Co-administration of Dacihep 60 mg Tablet with mifepristone may significantly increase the levels of Dacihep 60 mg Tablet, which may increase the risk of side effects.

How to manage the interaction:
Taking Dacihep 60 mg Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as headache, fatigue, nausea, and diarrhea. Do not discontinue any medications without consulting a doctor.
DaclatasvirModafinil
Severe
How does the drug interact with Dacihep 60 mg Tablet:
Combining Dacihep 60 mg Tablet with Modafinil may significantly reduce the blood levels of Dacihep 60 mg Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Dacihep 60 mg Tablet with Modafinil together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like Fatigue, Fever, Jaundice, Pain in the right upper abdomen, Abdominal swelling, or Dark urine make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DaclatasvirFosphenytoin
Severe
How does the drug interact with Dacihep 60 mg Tablet:
When Dacihep 60 mg Tablet is taken with Fosphenytoin, it can cause the body to process Dacihep 60 mg Tablet faster and reduce its levels in the body.

How to manage the interaction:
Although taking Dacihep 60 mg Tablet and Fosphenytoin together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms of Fatigue, Fever, Itching, Jaundice, Pain or swelling in the right upper abdomen, Dark urine, or Clay-colored or pale stools, it's important to contact your doctor right away. They may be able to recommend other options for treatment that won't cause any interactions with your current medications. Do not stop using any medications without a doctor's advice.
DaclatasvirEfavirenz
Severe
How does the drug interact with Dacihep 60 mg Tablet:
When Dacihep 60 mg Tablet is taken with Efavirenz, the levels and effectiveness of Dacihep 60 mg Tablet may be reduced.

How to manage the interaction:
Taking Dacihep 60 mg Tablet with Efavirenz together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
DaclatasvirPhenytoin
Severe
How does the drug interact with Dacihep 60 mg Tablet:
Coadministration of Phenytoin and Dacihep 60 mg Tablet may decrease the blood levels of Dacihep 60 mg Tablet, which may make Dacihep 60 mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Dacihep 60 mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
DaclatasvirColchicine
Severe
How does the drug interact with Dacihep 60 mg Tablet:
Coadministration of colchicine with Dacihep 60 mg Tablet may increase the blood levels of colchicine, increasing the risk of side effects.

How to manage the interaction:
Although taking Colchicine and Dacihep 60 mg Tablet together may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
DaclatasvirPhenobarbital
Severe
How does the drug interact with Dacihep 60 mg Tablet:
Phenobarbital can drastically lower Dacihep 60 mg Tablet levels in the blood, making the medicine less effective.

How to manage the interaction:
Although taking phenobarbital with Dacihep 60 mg Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Dacihep 60 mg Tablet when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Dacihep 60 mg Tablet is used to treat Hepatitis C virus infection.
Dacihep 60 mg Tablet contains Daclatasvir, which works by blocking the activity of the hepatitis C virus in the liver cells. This causes viral DNA termination and reduces the amount of hepatitis C virus in the body.
Avoid receiving Dacihep 60 mg Tablet if you are allergic to it or other medicines of the same class. Also, this medicine should not be used along with CYP3A inducer drugs such as rifampicin, carbamazepine, phenytoin, etc., as it can cause serious adverse effects. Concomitant use of Dacihep 60 mg Tablet along with amiodarone should be avoided due to the risk of severe bradycardia (slow heart rate).
Yes, you can take Dacihep 60 mg Tablet either with food or on an empty stomach. Taking it at the same time every day is what matters most for keeping the drug level steady in your body. If you have a sensitive stomach, taking it with a meal may help prevent mild nausea. Talk to your doctor or pharmacist if you need more tips on taking your medication.
If you remember within 20 hours of your missed dose, take it immediately and then continue your regular schedule. If more than 20 hours have passed, skip that dose and take the next one at your normal scheduled time. Never take two doses at once to make up for a missed one. Talk to your doctor or pharmacist if you regularly struggle to remember your doses.
It is strongly advised to avoid alcohol entirely while taking Dacihep 60 mg Tablet . Alcohol damages liver cells and can slow down your liver’s healing process, making your hepatitis C treatment less effective. To give your liver the best chance to recover, stay away from alcohol. Talk to your doctor or pharmacist for support with lifestyle changes.
The safety of Dacihep 60 mg Tablet during pregnancy and breastfeeding is not fully established, and it is always used with other medications which may have their own risks. You must tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this drug. Talk to your doctor or pharmacist to understand the safest options for you.
The duration of your treatment depends on your specific hepatitis C genotype, your liver health, and how well you tolerate the medication, but it typically ranges from 12 to 24 weeks. It is vital that you complete the entire course prescribed by your doctor, even if you feel much better early on. Talk to your doctor or pharmacist if you have questions about your treatment plan.
No, Dacihep 60 mg Tablet cannot be used on its own. It must always be taken in combination with other direct-acting antiviral medications to successfully clear the hepatitis C virus. Taking it alone can make the virus resistant to treatment. Talk to your doctor or pharmacist about the specific combination of medications prescribed for you.
Yes, Dacihep 60 mg Tablet interacts strongly with St. John's wort, which can severely lower the level of the medicine in your blood and prevent it from working. Avoid taking this herbal supplement and discuss all other vitamins or over-the-counter products you take with your healthcare provider. Talk to your doctor or pharmacist before starting any new supplements.
A slow heart rate is a serious risk, especially if you take Dacihep 60 mg Tablet alongside other antivirals and a heart medication called amiodarone. If you experience dizziness, fainting, shortness of breath, or chest pain, seek emergency medical care immediately. Talk to your doctor or pharmacist if you have a history of heart conditions before starting this medicine.
Yes. Dacihep 60 mg Tablet is used as part of a combination treatment for hepatitis C and is not used alone. It may be prescribed with other antiviral medicines, such as sofosbuvir. The combination used depends on factors such as the type of hepatitis C infection, your liver health, previous treatment, and other health conditions. Your doctor will determine the treatment regimen that is appropriate for you.

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Reference

  1. U.S. Food and Drug Administration (FDA). 206843S006Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A615044 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Center for Biotechnology Information (NCBI). Nbk547875 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  4. ScienceDirect Topics. Daclatasvir - Research & Medical Applications Summary. Amsterdam, Netherlands: Elsevier; 2025. [Accessed on 02 Jun. 2026]Check here
  5. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. 2012. [Accessed on 29 Dec. 2025]Check here
  6. EUROPEAN EGYPTIAN PHARM. IND. Daclavir 60mg Film Coated Tablet. [Revised in April 2018] [Accessed on 8th September 2022] 20190401 164410 .pdfCheck here

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India
Other Info - DAC0053
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