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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dabigat 150 Capsule is used to prevent the formation of blood clots. It contains Dabigatran etexilate mesylate which works by blocking coagulation factor (thrombin) in the blood and prevents blood clot formation. In some cases, this medicine may cause side effects such as bleeding, stomach pain, nausea, and indigestion. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dabigat 150 Capsule

Dabigat 150 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Dabigat 150 Capsule is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Dabigat 150 Capsule contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabigat 150 Capsule preventing blood clot formation in the body.

Take Dabigat 150 Capsule as prescribed by your doctor. You are advised to take Dabigat 150 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Dabigat 150 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Dabigat 150 Capsule or any other medicines, please tell your doctor. Dabigat 150 Capsule should not be taken in the conditions like bleeding disorder, or kidney disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Dabigat 150 Capsule . Dabigat 150 Capsule should not be used for children below 18 years of age. Dabigat 150 Capsule has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Dabigat 150 Capsule as it may increase the risk of bleeding.

Uses of Dabigat 150 Capsule

Prevention of blood clot

Directions for Use

• Dabigat 150 Capsule can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Dabigat 150 Capsule as a whole with a glass of water.• Do not open, break, or chew it.

Medicinal Benefits

Dabigat 150 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Dabigat 150 Capsule is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent blood clots in the heart and prevent heart attacks. Besides this Dabigat 150 Capsule is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. This Dabigat 150 Capsule may also be used to prevent the formation of blood clots after hip replacement surgery. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabigat 150 Capsule prevents blood clot formation in the body.

How Dabigat 150 Capsule Works

Dabigat 150 Capsule contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabigat 150 Capsule preventing blood clot formation in the body.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Dabigat 150 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

What if I have taken an overdose of Dabigat 150 Capsule

Take Dabigat 150 Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include unusual/prolonged bleeding, bloody/tarry/black stools, and pink/dark urine. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Dabigat 150 Capsule or any other medicines, please tell your doctor. Dabigat 150 Capsule should not be taken in the conditions like heart disease, bleeding problems, and kidney disease. Do not take Dabigat 150 Capsule if you have reduced function of the liver, which might cause death. Inform your doctor if you have a serious injury (bone fracture, head injury). People who have any spinal surgery are more likely to have bleeding problems around the spine when already on this Dabigat 150 Capsule . This bleeding infrequently occurs but can lead to not moving the body (paralysis) prolonged-term or paralysis that will not go away. Dabigat 150 Capsule should not be taken if you are older than 75 years. Before taking Dabigat 150 Capsule inform your doctor if you have a surgery in the past month. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Dabigat 150 Capsule .  Dabigat 150 Capsule should not be used for children below 18 years of age. Dabigat 150 Capsule has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Dabigat 150 Capsule as it may increase the risk of bleeding.

Drug-Drug Interactions

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Severe

Drug-Drug Interactions

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How does the drug interact with Dabigat 150 Capsule:
When Mifepristone is taken with Dabigat 150 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabigat 150 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Dabigat 150 Capsule:
Taking Dabigat 150 Capsule with Tipranavir can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 150 Capsule with Tipranavir together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 150 Capsule:
Coadministration of Dabigat 150 Capsule and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Dabigat 150 Capsule and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
Dabigatran etexilatePhenylbutazone
Severe
How does the drug interact with Dabigat 150 Capsule:
Taking Dabigat 150 Capsule with Phenylbutazone can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 150 Capsule with Phenylbutazone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 150 Capsule:
Taking Dabigat 150 Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 150 Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 150 Capsule:
Taking Dabigat 150 Capsule with Argatroban can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 150 Capsule with Argatroban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 150 Capsule:
Taking Dabigat 150 Capsule with Cabozantinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigat 150 Capsule with Cabozantinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigat 150 Capsule:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dabigat 150 Capsule:
Coadministration of Piroxicam with Dabigat 150 Capsule can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Dabigat 150 Capsule, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabigat 150 Capsule:
Co-administration of Dabigat 150 Capsule and Rivaroxaban can increase the risk of bleeding, including severe blood loss.

How to manage the interaction:
Co-administration of Dabigat 150 Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding, dizziness, tarry stools, coughing up or vomiting blood, or severe headache, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE MESILATE-150MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE MESILATE-150MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabigat 150 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabigat 150 Capsule treatment.

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  •  Opt for high vitamin K foods (liver, leafy green vegetables, or vegetable oils) as Dabigat 150 Capsule may lower Vitamin K in your body.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Dabigat 150 Capsule and lead to unwanted side effects. Hence try to avoid these juices while taking Dabigat 150 Capsule .
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Dabigat 150 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Dabigat 150 Capsule is a Category C pregnancy drug as the effect of Dabigat 150 Capsule is unknown on the mother and the unborn baby. Avoid the use of Dabigat 150 Capsule if you are pregnant and inform your doctor.

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Breast Feeding

Unsafe

Dabigat 150 Capsule should not be used while taking Dabigat 150 Capsule . Inform your doctor if you are a breastfeeding mother.

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Driving

Safe if prescribed

Dabigat 150 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Dabigat 150 Capsule with caution, especially if you have a history of Liver diseases/conditions. Dabigat 150 Capsule may increase the chances of mild liver injury. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Dabigat 150 Capsule with caution, especially if you have a history of Kidney diseases/conditions, as this Dabigat 150 Capsule may cause side effects. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Dabigat 150 Capsule should not be used for children below 18 years as it is not approved for children.

Have a query?

FAQs

Dabigat 150 Capsule is used to prevent blood clots. It is used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung).

People experiencing any uncommon bleeding or people allergic to Dabigat 150 Capsule should not take Dabigat 150 Capsule . People with artificial heart valves should also prevent Dabigat 150 Capsule . Dabigat 150 Capsule should not take those patients who have bleeding problems and heart disease. The use of this Dabigat 150 Capsule is not suggested in patients with serious kidney disease.

As compared to other blood thinner medicines, Dabigat 150 Capsule does not normally cause hair loss. Though, there do exist some unusual reports of hair loss related to Dabigat 150 Capsule . Inform your doctor if you observe hair loss while taking Dabigat 150 Capsule .

Yes, Dabigat 150 Capsule increases the risk of bleeding. Always be cautious while doing activities that may lead to an injury or bleeding. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Dabigat 150 Capsule works by blocking a substance (a protein known as thrombin) in the blood and preventing blood clot formation. Therefore, Dabigat 150 Capsule preventing blood clot formation in the body.

Unlike other blood thinners, Dabigat 150 Capsule generally does not affect the functioning of the liver. But long-term use of Dabigat 150 Capsule may raise the chances of mild liver injury in patients with a high level of liver enzymes. However, the complete chances of developing any such problem are lesser than other blood thinners. It is advisable to you that before starting this Dabigat 150 Capsule inform your doctor if you have a history of liver disease.

Dabigat 150 Capsule may increase the risk of bleeding during surgery. Therefore, the doctor might ask you to stop taking Dabigat 150 Capsule a few days before surgery.

You can take Dabigat 150 Capsule with or without food but try to take it at the same time every day. Dabigat 150 Capsule should be swallowed as a whole with water; do not crush or chew it.

Dabigat 150 Capsule should be taken as advised by the doctor. To help you remember to take Dabigat 150 Capsule , take it at around the same time daily.

You are recommended to avoid alcohol consumption with Dabigat 150 Capsule as it may increase the risk of bleeding.

Though Dabigat 150 Capsule starts working within a few hours of taking the medicine, you may not feel any better. Keep taking Dabigat 150 Capsule for the prescribed duration to treat your condition effectively.

Store Dabigat 150 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Dabigat 150 Capsule may cause side effects like bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Dabigat 150 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - DAB0378

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