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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Crescort Tablet 10's is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

Crescent Formulations Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Crescort Tablet 10's

Crescort Tablet 10's is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally and is unable to distinguish between foreign cells and native cells. This condition results in an immune system that starts to attack native cells and organs, leading to medical problems like Duchenne muscular dystrophy.

Crescort Tablet 10's is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Crescort Tablet 10's binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Crescort Tablet 10's is beneficial in autoimmune diseases and inflammation that cause harm to various organs, especially in joints with arthritis and the skin in psoriasis. Crescort Tablet 10's makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy.

Crescort Tablet 10's is available in both oral tablet and suspension dosage forms. The tablet form of Crescort Tablet 10's can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Crescort Tablet 10's can be taken as directed by your doctor, using a measuring cup. Your doctor will recommend how often you take Crescort Tablet 10's based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headaches, dizziness, skin rashes, tremors, nervousness, diarrhoea, and fast heartbeats. Most of the side effects of Crescort Tablet 10's do not require medical attention and usually resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, stomach upset, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may occur when the medication is stopped suddenly.

Before starting Crescort Tablet 10's, please inform your doctor that you are allergic or hypersensitive to Crescort Tablet 10's. Extra care is needed when a patient has an existing infection being treated (systemic infection) or has recently received live virus vaccines. A doctor's consultation is required as Crescort Tablet 10's is not safe to use during pregnancy.

Uses of Crescort Tablet 10's

Crescort Tablet 10's used in the treatment of Duchenne muscular dystrophy (DMD). The detailed uses of Crescort Tablet 10's are as follows:

  • Treatment of DMD: Crescort Tablet 10's used to treat Duchenne muscular dystrophy by slowing muscle degeneration, preserving strength, and improving mobility.
  • Anti-Inflammatory Treatment: Crescort Tablet 10's reduces inflammation and relieves symptoms associated with conditions like arthritis, bursitis, and tendinitis.
  • Autoimmune Disorders Management: Crescort Tablet 10's helps to manage autoimmune diseases like lupus and multiple sclerosis by suppressing the immune response.
  • Relief from Allergic Reactions: Crescort Tablet 10's provides relief from symptoms of allergic reactions, such as allergic rhinitis, by reducing inflammation and immune response.
  • Managing Respiratory Conditions: Crescort Tablet 10's is also involved in managing respiratory conditions like asthma and COPD by reducing airway inflammation.
  • Skin Disorders Treatment: Crescort Tablet 10's treats skin conditions like eczema and psoriasis by reducing inflammatory responses.

Directions for Use

• Crescort Tablet 10's can be taken with or without food. • It is usually taken once daily at the same time each day or as prescribed by your doctor. • Swallow Crescort Tablet 10's as a whole with a glass of water. • Do not crush or chew this medication. • If you cannot swallow the tablet as a whole, you may break it in half and take both halves separately.

Medicinal Benefits

Crescort Tablet 10's is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Crescort Tablet 10's is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

How Crescort Tablet 10's Works

Crescort Tablet 10's is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Crescort Tablet 10's binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Crescort Tablet 10's is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis, skin, and psoriasis. Crescort Tablet 10's makes organ transplantation possible, and treats muscle disorders like Duchenne muscular dystrophy.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Crescort Tablet
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

What if I have taken an overdose of Crescort Tablet 10's

Do not take more than the prescribed dose of Crescort Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney and liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Crescort Tablet 10's.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Crescort Tablet 10's. Before taking Crescort Tablet 10's for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Crescort Tablet:
Co-administration of Crescort Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Coadministration of Darunavir with Crescort Tablet can increase the levels of Crescort Tablet in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Darunavir with Crescort Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Taking Modafinil with Crescort Tablet may significantly reduce the blood levels of Crescort Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Modafinil and Crescort Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Using Deferasirox together with Crescort Tablet may increase the risk of gastric and intestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Deferasirox with Crescort Tablet can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like stomach pain, dizziness, loss of appetite, nausea, vomiting, or black or tarry stools, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Coadministration of Voriconazole with Crescort Tablet can increase the levels of Crescort Tablet in the body, which increases risk/severity of side effects.

How to manage the interaction:
Taking Voriconazole with Crescort Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Coadministration of Erythromycin with Crescort Tablet can increase the levels of Crescort Tablet in the body.

How to manage the interaction:
Taking Erythromycin with Crescort Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Taking thalidomide together with Crescort Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Crescort Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
DeflazacortCertolizumab
Severe
How does the drug interact with Crescort Tablet:
Co-administration of Crescort Tablet with Certolizumab may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Crescort Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crescort Tablet:
Coadministration of Fosaprepitant with Crescort Tablet can increase the levels of Crescort Tablet in the body.

How to manage the interaction:
Taking Fosaprepitant with Crescort Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crescort Tablet:
Using Aspirin together with Crescort Tablet may increase the risk of gastric and intestinal ulcers, bleeding and perforation.

How to manage the interaction:
Co-administration of Aspirin with Crescort Tablet can result in an interaction, but it can be taken if a doctor has advised it. If you have any symptoms unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Crescort Tablet therapy may elevate Crescort Tablet levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Diet & Lifestyle Advise

A patient needs to take extra care of their hygiene and stay away from places or people believed to be a cause of infection, as this drug affects the immune system. Therefore, proper care is necessary.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS
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Alcohol

Caution

The effect of taking both alcohol and Crescort Tablet 10's may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Crescort Tablet 10's crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Crescort Tablet 10's can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Crescort Tablet 10's.

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Kidney

Caution

Before using Crescort Tablet 10's by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Crescort Tablet 10's is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Crescort Tablet 10's.

Have a query?

FAQs

Crescort Tablet 10's is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.

Not recommended in mild allergies. Crescort Tablet 10's is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.

It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.

It is not recommended to be taken Crescort Tablet 10's with alcohol as it may cause stomach bleeding.

No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Crescort Tablet 10's may be used in extreme cases of seasonal allergy.

You should not use Crescort Tablet 10's if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Crescort Tablet 10's if you have a compromised immune system, eye problems or weak bones.

Yes, Crescort Tablet 10's is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.

Crescort Tablet 10's is less potent than Prednisone and is usually administered proportionately in higher doses.

No, Crescort Tablet 10's is not a painkiller. It is a steroid medication.

Yes, it can be used to treat kidney stones.

Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.

Yes, it is safe to use Crescort Tablet 10's if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.

Common side effects of Crescort Tablet 10's may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Crescort Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

Country of origin

India

Manufacturer/Marketer address

Sco-58, 59, Sector-17D Chandigarh-160017
Other Info - CRE0443

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