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  3. Coversyl AM 4/5 Tablet 10's

Coversyl AM 4/5 Tablet 10's, Pack of 10 TABLETS
Coversyl AM 4/5 Tablet 10's, Pack of 10 TABLETS
Coversyl AM 4/5 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Coversyl AM 4/5 Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Perindopril, which relaxes and widens the blood vessels, so that blood passes through them easily, thereby lowering the blood pressure and makes it easier for your heart to pump blood around your body. Thus, it lowers high blood pressure, reducing the risk of heart attack or stroke. It may cause side effects such as ankle swelling, tiredness, headache, palpitations (irregular heartbeat), sleepiness, the increased potassium level in the blood, cough, flushing (sense of heat in the face, ears, neck, and trunk), taste change, decreased blood pressure, and upset stomach. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

AMLODIPINE-5MG + PERINDOPRIL-4MG

Manufacturer/Marketer :

Serdia Pharmaceuticals India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Coversyl AM 4/5 Tablet

Coversyl AM 4/5 Tablet is used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel's walls. This condition makes the heart work harder in pumping the blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Coversyl AM 4/5 Tablet contains Amlodipine (calcium channel blocker) and Perindopril (angiotensin-converting enzyme inhibitor). Amlodipine relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. Perindopril relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. Thus, collectively, both help lower high blood pressure, reducing heart attack or stroke chances. 

Take Coversyl AM 4/5 Tablet as prescribed by your doctor. You may experience ankle swelling, tiredness, headache, palpitations (irregular heartbeat), sleepiness, increased potassium level in the blood, cough, flushing (sense of heat in the face, ears, neck, and trunk), Taste change, decreased blood pressure, and upset stomach.

Do not stop taking Coversyl AM 4/5 Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. If you have angioedema (Painless swelling under the skin), diabetes then inform your doctor immediately. If you have kidney disease, you may not use Coversyl AM 4/5 Tablet with Aliskiren (other blood pressure-lowering pills). Reducing the amount of table salt (sodium chloride) in your food. Immediately contact your doctor if you have heart disease, kidney disease, liver disease, and high potassium levels in your blood. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Coversyl AM 4/5 Tablet can be prescribed accordingly.

Uses of Coversyl AM 4/5 Tablet

Treatment of Hypertension (high blood pressure).

Directions for Use

• Take Coversyl AM 4/5 Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Coversyl AM 4/5 Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Perindopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. On the other hand, Perindopril is an angiotensin-converting enzyme (ACE) inhibitor, it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. However, Coversyl AM 4/5 Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Coversyl AM 4/5 Tablet also reduces the physical effects of anxiety.

How Coversyl AM 4/5 Tablet Works

Coversyl AM 4/5 Tablet contains Amlodipine (calcium channel blocker) and Perindopril (angiotensin-converting enzyme inhibitor). Amlodipine relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. Perindopril relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. Thus, collectively, both help lower high blood pressure, reducing heart attack or stroke chances.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Coversyl AM 4/5 Tablet
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Coversyl AM 4/5 Tablet

Do not take more than the prescribed dose of Coversyl AM 4/5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not stop taking Coversyl AM 4/5 Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. If you have angioedema (Painless swelling under the skin), diabetes then inform your doctor immediately. If you have kidney disease, you may not use Coversyl AM 4/5 Tablet with aliskiren (other blood pressure-lowering pills). Reducing the amount of table salt (sodium chloride) in your food.  Avoid potassium, containing food. Immediately contact your doctor if you have heart disease, kidney disease, liver disease, diabetes, and high potassium level in your blood. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Coversyl AM 4/5 Tablet can be prescribed accordingly.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
PerindoprilAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Coversyl AM 4/5 Tablet:
Using Coversyl AM 4/5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Coversyl AM 4/5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
PerindoprilAliskiren
Critical
How does the drug interact with Coversyl AM 4/5 Tablet:
Combining Aliskiren with Coversyl AM 4/5 Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Coversyl AM 4/5 Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AmlodipineCarbamazepine
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Coadministration of Coversyl AM 4/5 Tablet and carbamazepine together may significantly reduce Coversyl AM 4/5 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Coversyl AM 4/5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Coadministration of Coversyl AM 4/5 Tablet with itraconazole may significantly raise the blood levels and effects of Coversyl AM 4/5 Tablet.

How to manage the interaction:
Coversyl AM 4/5 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineTizanidine
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Co-administration of Tizanidine and Coversyl AM 4/5 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Coversyl AM 4/5 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Coadministration of Coversyl AM 4/5 Tablet and Rifapentine may significantly reduce the blood levels of Coversyl AM 4/5 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Coversyl AM 4/5 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineRifabutin
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Using Coversyl AM 4/5 Tablet and rifabutin together may lower Coversyl AM 4/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Coversyl AM 4/5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Coadministration of lemborexant and Coversyl AM 4/5 Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Coversyl AM 4/5 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
Co-administration of Coversyl AM 4/5 Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Coversyl AM 4/5 Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineFosphenytoin
Severe
How does the drug interact with Coversyl AM 4/5 Tablet:
When Coversyl AM 4/5 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Coversyl AM 4/5 Tablet, which may make Coversyl AM 4/5 Tablet less effective.

How to manage the interaction:
Although taking Coversyl AM 4/5 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+PERINDOPRIL-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+PERINDOPRIL-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Coversyl AM 4/5 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Coversyl AM 4/5 Tablet.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, use only one serving for women and two servings for men.

  • Quit smoking to lower the risk of heart diseases.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.

  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.

  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Coversyl AM 4/5 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Coversyl AM 4/5 Tablet interacts with alcohol. Therefore alcohol is not safe.

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Pregnancy

Unsafe

The use of Coversyl AM 4/5 Tablet is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the unborn baby. Hence, you should always consult your doctor before using Coversyl AM 4/5 Tablet .

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Breast Feeding

Caution

Use of Coversyl AM 4/5 Tablet is not recommended during the breastfeeding stage unless recommended by your doctor.

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Driving

Caution

Coversyl AM 4/5 Tablet may cause dizziness and sleepiness. Therefore, drive with caution while using Coversyl AM 4/5 Tablet .

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Coversyl AM 4/5 Tablet . Coversyl AM 4/5 Tablet is to be administered with caution in patients with severe hepatic impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Coversyl AM 4/5 Tablet . Coversyl AM 4/5 Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment.

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Children

Unsafe

Coversyl AM 4/5 Tablet is not recommended for use in children.

Have a query?

FAQs

Coversyl AM 4/5 Tablet is used to treat hypertension (high blood pressure).

Coversyl AM 4/5 Tablet relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body.

Coversyl AM 4/5 Tablet is recommended to use in dose and duration as advised by the doctor. Do not stop taking Coversyl AM 4/5 Tablet on your own as it may lead to a sudden rise in blood pressure increases the risk of heart attack and stroke.

Coversyl AM 4/5 Tablet can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.

Coversyl AM 4/5 Tablet may increase blood potassium levels in people with diabetes, poor kidney function, and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Coversyl AM 4/5 Tablet if you have diabetes.

Even though your blood pressure becomes normal after using Coversyl AM 4/5 Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Yes, you can take Coversyl AM 4/5 Tablet with or without food. However, it is recommended that you take it at the same time each day to maintain consistent blood levels.

Common side effects of Coversyl AM 4/5 Tablet may include ankle swelling, tiredness, headache, palpitations (irregular heartbeat), sleepiness, increased potassium level in the blood, cough, flushing (sense of heat in the face, ears, neck, and trunk), Taste change, decreased blood pressure, and upset stomach.

Coversyl AM 4/5 Tablet should be avoided during pregnancy as it can harm the unborn baby. It's generally advised to avoid Coversyl AM 4/5 Tablet while breastfeeding. Consult your doctor for personalized advice.

If you have kidney or liver problems, allergies, or diabetes, inform your doctor before taking Coversyl AM 4/5 Tablet . Regular monitoring of potassium and blood sugar levels may be necessary.

Store Coversyl AM 4/5 Tablet in a cool, dry place, away from light and moisture. Keep it out of the reach of children and pets.

It may take a few weeks for the whole blood pressure-lowering effect of Coversyl AM 4/5 Tablet to be felt. However, some people may notice a difference in blood pressure within a few days.

Yes, Coversyl AM 4/5 Tablet can cause a dry cough. This is a common side effect, especially in the early stages of treatment. If the cough becomes bothersome, talk to your doctor.

No, you should not stop taking Coversyl AM 4/5 Tablet suddenly. Doing so can cause a sudden spike in blood pressure. If you must stop taking it, your doctor will gradually reduce your dosage.

Inform your doctor about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medicines may interact with Coversyl AM 4/5 Tablet .

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and take the scheduled dose. Do not double the dose.

Yes, Coversyl AM 4/5 Tablet can cause dizziness or lightheadedness, especially when you first start taking it. To minimize this risk, get up slowly from a sitting or lying position.

Yes, Coversyl AM 4/5 Tablet can cause swelling in the ankles or feet. This is a common side effect that usually goes away on its own. If the swelling is severe or bothersome, talk to your doctor.

Excessive alcohol consumption can lower blood pressure and interact with Coversyl AM 4/5 Tablet . It's best to avoid or limit your alcohol intake while taking Coversyl AM 4/5 Tablet .

While Coversyl AM 4/5 Tablet itself doesn't directly cause weight gain, it can contribute to weight gain by causing swelling or affecting appetite. If you're concerned about weight gain, talk to your doctor.

While rare, Coversyl AM 4/5 Tablet can cause a rash or skin irritation in some people. Stop taking the medication and contact your doctor immediately if you develop a rash or skin reaction.

In rare cases, Coversyl AM 4/5 Tablet can cause blurred vision or other eye-light changes. If you experience any vision problems, contact your doctor.

Yes, grapefruit and grapefruit juice can interact with Coversyl AM 4/5 Tablet , potentially increasing blood levels and leading to side effects. Avoid consuming grapefruit or grapefruit juice while taking this medication.

It's generally safe to take Coversyl AM 4/5 Tablet with over-the-counter pain relievers like paracetamol or ibuprofen. However, if you have concerns or are taking other medications, do not take them unless prescribed by the doctor.

Coversyl AM 4/5 Tablet contains Amlodipine (calcium channel blocker) and Perindopril (angiotensin-converting enzyme inhibitor).

Coversyl AM 4/5 Tablet may cause dizziness and drowsiness. Therefore, drive only if you are alerted after taking the Coversyl AM 4/5 Tablet .

Country of origin

India

Manufacturer/Marketer address

Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
Other Info - COV0015

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:42 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/food-interactions/amlodipine-perindopril.html
  2. https://www.medicines.org.uk/emc/files/pil.7197.pdf
  3. https://www.rxlist.com/prestalia-drug.htm

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