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Comtus-LC Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of dry cough. This medicine works by blocking the action of histamine and transmission of nerve signals from the cough centre in the brain to the muscles that produce cough thus reduce cough associated with cold/flu, allergies, and throat irritation. You may experience common side effects like headache, dizziness, numbness, drowsiness, or nausea.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-2MG+LEVODROPROPIZINE-30MG

Manufacturer/Marketer :

Comed Chemicals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Comtus-LC Syrup

Comtus-LC Syrup is an oral liquid medicine used to treat dry, unproductive coughs associated with allergies. It helps ease tickling throat sensations and controls the body's overactive cough reflex. This medication is primarily prescribed to relieve respiratory discomfort caused by upper airway irritation.

For the best results, take Comtus-LC Syrup consistently at the times prescribed by your healthcare provider. You can take this oral liquid with or without food, though taking it with meals can help prevent stomach upset. Additionally, maintaining comfortable indoor humidity and drinking plenty of warm fluids can help support your recovery.

Some people may experience mild side effects while taking this medication, such as drowsiness, dry mouth, or mild stomach discomfort. If you experience serious side effects like severe dizziness, extreme drowsiness, or a severe allergic skin rash, contact your doctor immediately. Always consult your doctor if any unexpected symptoms persist or worsen.

Talk to your doctor before taking Comtus-LC Syrup if you have glaucoma, liver problems, or difficulty urinating. Do not take this if you have severe lung disease or if you are currently taking certain medications for depression. It is also not suitable for individuals with a known allergy to any of its active components.

Avoid drinking alcohol or smoking while using this medicine, as they can worsen drowsiness and increase airway irritation. Speak to your doctor or pharmacist if you are pregnant, breastfeeding, or if you are caring for an elderly individual, as special precautions may be needed.

Uses of Comtus-LC Syrup

Comtus-LC Syrup is used to treat dry cough. The detailed uses of Comtus-LC Syrup are as follows:

  • Dry Cough: Comtus-LC Syrup helps calm a dry, tickly cough by acting on the nerves in your chest and airways to reduce the frequent urge to cough.
  • Allergic Rhinitis: This medicine relieves upper respiratory allergy symptoms, such as a runny nose, sneezing, an itchy nose, and watery eyes.
  • Throat Irritation: By calming persistent coughing, it provides your throat tissues with a chance to rest and heal from constant irritation.

Key Benefits

Comtus-LC Syrup offers targeted relief by addressing both the allergic reaction and the cough reflex at the same time.

Benefits may include:

  • By combining multiple active ingredients, Comtus-LC Syrup helps relieve cough and associated symptoms without the need to manage multiple medications.
  • By calming throat irritation and reducing cough caused by postnasal drip, Comtus-LC Syrup helps reduce nighttime coughing, allowing you to sleep more comfortably.
  • It acts primarily on the nerves in the airways to help calm the cough reflex, providing effective cough relief. Depending on the formulation, some people may still experience mild drowsiness.
  • By reducing persistent coughing and throat irritation, Comtus-LC Syrup helps you carry out your daily activities with greater ease and comfort.

Directions for Use

  • Comtus-LC Syrup can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Shake the bottle well before each use.
  • Measure the prescribed dose using the measuring cup/dosing syringe/dropper provided with the pack and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

How Comtus-LC Syrup Works

Comtus-LC Syrup is a combination medicine that contains two active ingredients: levodropropizine and chlorpheniramine maleate. Together, they target the physical causes of dry coughs and allergies to bring you relief. Levodropropizine works as a peripheral cough suppressant. Instead of acting on your brain, it acts directly on the sensory nerves located in your respiratory tract. By calming these sensitive nerves, it stops them from sending constant cough signals to your brain, which reduces the frequency of your dry cough. Chlorpheniramine maleate is an antihistamine. During an allergic reaction, your body releases a chemical called histamine, which causes a runny nose, sneezing, and watery eyes. Chlorpheniramine blocks the action of histamine in your body, drying up secretions and stopping the allergic response. Together, these two actions help you breathe more comfortably.
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Alcohol

Unsafe

Avoid consumption of alcohol with Comtus-LC Syrup as it may increase the adverse effects. Please consult a doctor before consuming alcohol with Comtus-LC Syrup.

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Pregnancy

Caution

The safety of Comtus-LC Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Comtus-LC Syrup may be excreted in breast milk and cause harm to the baby. Therefore, Comtus-LC Syrup should not be used in breastfeeding mothers without a doctor’s advice.

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Driving

Caution

Comtus-LC Syrup may cause dizziness, drowsiness, blurred vision or impaired thinking in some people. Therefore, drive only if you are alert after taking Comtus-LC Syrup.

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Liver

Caution

Take Comtus-LC Syrup with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Comtus-LC Syrup with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Caution

Comtus-LC Syrup is not recommended for children below 2 years of age. Please consult a doctor before using Comtus-LC Syrup in children.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Comtus-LC Syrup. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Comtus-LC Syrup should be given to elderly patients only if prescribed by a doctor. Please consult your doctor before using Comtus-LC Syrup.

What if I have taken an overdose of Comtus-LC Syrup

If you take too much of this medicine, seek emergency medical help immediately. Overdose symptoms can include extreme sleepiness, severe dizziness, confusion, a rapid heartbeat, or restlessness, especially in children.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of warm fluids, such as warm water, broth, or decaffeinated herbal tea, to keep your throat moist and soothe irritation.
  • Keep the air moist: Use a cool-mist humidifier in your room, especially at night, to prevent dry air from triggering coughing fits.
  • Avoid airway irritants: Avoid exposure to tobacco smoke, heavy pollution, dust, and strong chemical fumes, which can irritate your airways and make your cough worse.
  • Prevent acid reflux: Avoid eating heavy, spicy, or acidic meals close to bedtime, as acid reflux can travel up the oesophagus and trigger dry coughing.
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How Soon It Starts Working

The time required for Comtus-LC Syrup to start to work: Comtus-LC Syrup ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Comtus-LC Syrup last: The effect of Comtus-LC Syrup lasts for 6 to 8 hours.

What if you forget to take Comtus-LC Syrup

If you miss a dose of Comtus-LC Syrup, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Comtus-LC Syrup at room temperature, between 15°C and 30°C (59°F to 86°F), in a cool, dry place.

Drug Warnings

  • Shake well before use: Always shake the bottle well before each use to ensure the active ingredients are mixed evenly throughout the liquid.
  • Use caution with activities requiring alertness: Avoid driving, operating machinery, or performing any hazardous tasks until you know how this medicine affects you, as it can cause significant drowsiness.
  • Avoid certain medicines: Do not take this medicine alongside other antihistamines, sleeping pills, or muscle relaxants without checking with your healthcare provider first.
  • Monitor your symptoms: If your cough does not improve within 7 days, or if you develop a high fever, severe skin rash, or persistent headache, stop taking the liquid and consult your doctor.

Drug-Drug Interactions

verifiedApollotooltip
  • Central nervous system depressants (such as sleeping pills, anxiety medications, muscle relaxants, or opioid pain relievers): May cause severe drowsiness and slowed breathing.
  • Anti-depressant medicines: Using this medication at the same time as monoamine oxidase inhibitors (MAOIs) can cause serious side effects, including dangerous spikes in blood pressure.
  • Other antihistamines: May increase your risk of dry mouth, blurred vision, and difficulty urinating.
Chlorpheniramine + LevodropropizinePotassium chloride
Critical
Chlorpheniramine + LevodropropizinePotassium citrate
Critical

Drug-Drug Interactions

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Chlorpheniramine + LevodropropizinePotassium chloride
Critical
How does the drug interact with Comtus-LC Syrup 60 ml:
Taking Comtus-LC Syrup 60 ml together with Potassium chloride (in tablet or capsule form) can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Comtus-LC Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + LevodropropizinePotassium citrate
Critical
How does the drug interact with Comtus-LC Syrup 60 ml:
Taking Comtus-LC Syrup 60 ml together with Potassium citrate (in tablet or capsule form) can increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Taking Comtus-LC Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + LevodropropizineSodium oxybate
Severe
How does the drug interact with Comtus-LC Syrup 60 ml:
Taking Comtus-LC Syrup 60 ml with Sodium oxybate can enhance the risk of side effects.

How to manage the interaction:
Co-administration of Comtus-LC Syrup 60 ml with Sodium oxybate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience- drowsiness, dizziness, lightheadedness, confusion, low blood pressure, breathing difficulty, and impairment in thinking, judgment, and motor coordination, consult a doctor. You should take care when getting up from a sitting or lying posture, and avoid operating machinery, driving, or participating in any potentially dangerous activity requiring mental attention and motor coordination for at least six hours after taking sodium oxybate. Do not discontinue using any medications without a doctor's advice.
Chlorpheniramine + LevodropropizineIdelalisib
Severe
How does the drug interact with Comtus-LC Syrup 60 ml:
Taking Comtus-LC Syrup 60 ml together with Idelalisib can increase the levels of Chlorpheniramine which may lead to side effects.

How to manage the interaction:
Although taking Comtus-LC Syrup 60 ml together with Idelalisib can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + LevodropropizineTopiramate
Severe
How does the drug interact with Comtus-LC Syrup 60 ml:
Taking Comtus-LC Syrup 60 ml with Topiramate can increase the risk of side effects including high body temperatures and decreased sweating, sun stroke.

How to manage the interaction:
Although taking Comtus-LC Syrup 60 ml together with Topiramate can result in an interaction, it can be taken if your doctor has advised it. During warm weather and when exercising, you should drink lots of fluids. If your sweating is less than usual or you have a fever, if you feel lightheaded or dizzy, consult a doctor. Avoid activities requiring mental attention such as driving or operating dangerous machinery. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + LevodropropizineKetamine
Severe
How does the drug interact with Comtus-LC Syrup 60 ml:
Co-administration of Comtus-LC Syrup 60 ml with Ketamine can increase the risk of side effects.

How to manage the interaction:
Taking Comtus-LC Syrup 60 ml together with Ketamine can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, drowsiness, confusion, difficulty concentrating, and breathing difficulty. Avoid activities requiring mental focus such as driving, operating dangerous machinery. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Do not drink alcohol while taking Comtus-LC Syrup, as alcohol can dramatically increase drowsiness, dizziness, and impair your mental and physical coordination.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[EXPECTORANT AND COUGH PRODUCTS]

FAQs

Comtus-LC Syrup belongs to a class of medication called cough and cold preparations used to treat dry cough.
Comtus-LC Syrup contains Levodropropizine and Chlorpheniramine maleate. Levodropropizine works by decreasing the activity of the cough centre in the brain. Thus, decreases the urge to cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
No, you are not recommended to consume alcohol with Comtus-LC Syrup as it may increase drowsiness. However, please consult a doctor before consuming alcohol with Comtus-LC Syrup.
Yes, Comtus-LC Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Comtus-LC Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene. However, if the condition persists or worsens, please consult a doctor.
Comtus-LC Syrup may be used to provide relief from allergic symptoms such as sneezing, runny nose, throat irritation or watery eyes. Comtus-LC Syrup contains Chlorpheniramine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
You are recommended to avoid taking Comtus-LC Syrup if you have asthma, glaucoma, enlarged prostate, urinary problems, blockage in the stomach or intestines. However, if you have any of these conditions, please inform your doctor before taking Comtus-LC Syrup.
Comtus-LC Syrup is not recommended for children below 2 years of age. However, Comtus-LC Syrup should be used with caution in children above 2 years if prescribed by a doctor as misuse of Comtus-LC Syrup in children may lead to serious adverse effects.
You are recommended to take Comtus-LC Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after 1 week of using Comtus-LC Syrup, please consult your doctor.
No, you are not recommended to stop taking Comtus-LC Syrup without consulting your doctor as it may worsen cough or cause recurring symptoms. Therefore, take Comtus-LC Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Comtus-LC Syrup, please consult your doctor.
Yes, Comtus-LC Syrup may cause sleepiness or drowsiness as a common side effect. If you experience sleepiness or drowsiness, avoid driving and operating heavy machinery unless you feel fully alert.
Serious side effects with Comtus-LC Syrup are rare and uncommon. However, contact the doctor immediately if you notice any allergic reactions, skin rash or peeling, mouth ulcers, breathing difficulties, frequent fevers or infections, vision disturbances, or fast or irregular heartbeat.
No, taking more than the recommended dose of Comtus-LC Syrup will not be effective, rather it may cause unpleasant side effects. Therefore, always take Comtus-LC Syrup in the prescribed doses to prevent adverse effects and to get full benefits.
No, you should not breastfeed while taking Comtus-LC Syrup without consulting the doctor, as it may pass into breastmilk and cause harm to the baby. Therefore, consult the doctor before taking Comtus-LC Syrup if you are a breastfeeding woman.
You should not take Comtus-LC Syrup if you are allergic to any of its ingredients and avoid taking over-the-counter medications without a doctor’s advice.
Comtus-LC Syrup should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
The side effects of Comtus-LC Syrup include constipation, dry mouth, drowsiness, vomiting, blurred vision, dizziness or tiredness. Consult the doctor if any of these symptoms persist or worsen.
Comtus-LC Syrup is designed to treat dry, tickly, and unproductive coughs. Using a cough suppressant for a wet cough with mucus can prevent your lungs from clearing out phlegm, which is not recommended. Talk to your doctor to find the most suitable treatment for your cough.
While Comtus-LC Syrup does not contain decongestants that typically raise blood pressure, it is always safest to consult your doctor before taking any cough and cold medications if you have hypertension. Talk to your doctor to ensure this medicine is safe for you.
The safety of Comtus-LC Syrup during pregnancy has not been fully established. It should only be used if specifically prescribed by a healthcare provider who has weighed the benefits against the potential risks. Talk to your doctor before taking this medicine if you are pregnant.
Normal amounts of tea or coffee do not have a direct, dangerous interaction with Comtus-LC Syrup. However, because caffeine is a stimulant and this medicine can make you sleepy, mixing them might make it hard to judge how drowsy you actually are. Talk to your doctor if you have concerns.

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Country of origin

India

Manufacturer/Marketer address

2Nd Floor, Sun Plaza-I, Nr. Vadsar Bridge, Gidc Road, Makarpura, Vadodara - 390 010
Other Info - COM0788
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