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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Comcapsy 700 mg/30 mg Tablet is an antineoplastic (anticancer) medication used to treat metastatic breast cancer. It contains Capecitabine and Cyclophosphamide, which work by damaging the genetic material of cancer cells and stopping their growth and multiplication. It may sometimes cause common side effects, such as nausea, vomiting, loss of appetite, diarrhoea, stomach pain, skin rash, weakness, tiredness, fever, mouth sores, and hair loss. Before taking this medication, inform your doctor if you are allergic to any of its ingredients or other cancer medicines, are pregnant or breastfeeding, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Comcapsy 700 mg/30 mg Tablet

Comcapsy 700 mg/30 mg Tablet belongs to a group of medications called 'antineoplastic agents,' primarily used to treat metastatic breast cancer. Cancer occurs when cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissues and may sometimes spread to other areas of the body (known as metastasis).

Comcapsy 700 mg/30 mg Tablet contains two anticancer medications: Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both drugs exhibit potential synergistic effects; Cyclophosphamide boosts the activity of an enzyme (thymidine phosphorylase) that helps convert Capecitabine into its active form, 5-fluorouracil. They work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 700 mg/30 mg Tablet helps treat cancer by killing cancer cells.

You are advised to take Comcapsy 700 mg/30 mg Tablet for as long as your doctor has prescribed it, depending on your medical condition. In some cases, you may experience common side effects, such as nausea, vomiting, loss of appetite, diarrhoea, stomach pain, skin rash, weakness, tiredness, mouth sores, hair loss, fever, low blood cell count, and hand-foot syndrome (swelling, redness, and peeling on palms and soles). If you experience any of these side effects, do not hesitate to report them clearly to your doctor.

Do not use Comcapsy 700 mg/30 mg Tablet if you are allergic to any of its ingredients, fluorouracil, other cancer medicines, or have severe kidney disease or bladder obstruction. Inform your doctor before taking Comcapsy 700 mg/30 mg Tablet if you had treatment with chemotherapy and radiation or have certain medical conditions, including metabolic disorders, chronic infection, a weakened immune system, urination problems, or heart, lung, liver, or kidney diseases. Tell your doctor if you are taking any blood thinners (warfarin) before using Comcapsy 700 mg/30 mg Tablet , as it may increase the risk of severe bleeding. Avoid taking Comcapsy 700 mg/30 mg Tablet if you are pregnant or breastfeeding, as it may cause harmful effects on the baby. Comcapsy 700 mg/30 mg Tablet may cause dizziness or vision problems, so avoid driving and operating machines until you are fully alert.

Uses of Comcapsy 700 mg/30 mg Tablet

Comcapsy 700 mg/30 mg Tablet is used to treat metastatic breast cancer. The detailed uses of Comcapsy 700 mg/30 mg Tablet are as follows:

  • Manages advanced breast cancer: Comcapsy 700 mg/30 mg Tablet helps slow the growth and spread of cancer that has metastasized beyond the breast.
  • Reduces tumor size: Comcapsy 700 mg/30 mg Tablet works by interfering with cancer cell division, helping shrink tumors.
  • Supports combination therapy: Comcapsy 700 mg/30 mg Tablet is often used along with other anticancer treatments to improve overall effectiveness.

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Directions for Use

  • Take Comcapsy 700 mg/30 mg Tablet within 30 minutes after meals or as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Comcapsy 700 mg/30 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Comcapsy 700 mg/30 mg Tablet is an anticancer medication primarily used to treat metastatic breast cancer. It is also used in combination with other medicines to treat various types of cancer, as advised by a doctor, including colorectal, colon, stomach, pancreatic, and ovarian cancer. It contains Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 700 mg/30 mg Tablet effectively treats cancer by killing cancer cells.

How Comcapsy 700 mg/30 mg Tablet Works

Comcapsy 700 mg/30 mg Tablet contains two anticancer medications: Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both drugs exhibit potential synergistic effects; Cyclophosphamide boosts the activity of an enzyme (thymidine phosphorylase) that helps convert Capecitabine into its active form, 5-fluorouracil. They work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 700 mg/30 mg Tablet helps treat cancer by killing cancer cells.

Storage

• Store in a cool and dry place away from sunlight.• Keep Comcapsy 700 mg/30 mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Comcapsy 700 mg/30 mg Tablet
  • Apply fragrance-free, thick moisturizing creams to your hands and feet, gently pat the skin and dry instead of rubbing.
  • Use ice packs wrapped in a towel to soothe irritated areas on your palms and soles.
  • Wash your hands and feet with mild, unperfumed soap and avoid using harsh cleaning products.
  • Wear loose-fitting, well-cushioned shoes that provide ample space for your feet.
  • Practice wearing cotton gloves when doing chores that may irritate your hands.
  • Avoid hot baths or showers, instead opt for lukewarm water.
  • Wear sunscreen with a high SPF on exposed skin and limit sun exposure.
  • Don't expose your hands and feet to direct heat like or fireplaces.
  • Reduce pressure by avoiding activities that put pressure on your hands and feet, like jogging or heavy lifting.
  • If required, go for low-impact exercises like walking or swimming.
  • To reduce swelling elevate your feet when resting.
  • Consult your doctor if redness or blistering on your palms or soles, severe pain or discomfort in your hands and feet, open sores or bleeding on your skin or if significant worsening of symptoms.
  • Consult your doctor or healthcare provider before making any changes to your treatment plan or lifestyle modifications related to hand-foot syndrome.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
  • Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
  • Exercise regularly to maintain a good metabolism in your body.
  • Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
  • Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Bladder infection needs immediate medical attention when you observe blood in urine or have any abnormal changes in your body.
  • Get a physical examination and blood tests to identify factors that led to infection and initiate the treatment process immediately.
  • Avoid anxiety and stress, as it can worsen your condition.
  • Follow your doctor's instructions, and there can be medication with antibiotics and other supportive vitamins.
  • Take a balanced diet to prevent negative changes in your body.
  • Stay hydrated to support kidney and bladder health.
  • Rest on your back as advised by your doctor.
  • Limit physical strain for 1-2 weeks.
  • Avoid strenuous activities like running and contact sports.
  • Quit smoking to improve overall health.
  • Use pain medication responsibly.
  • Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
  • Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.

What if I have taken an overdose of Comcapsy 700 mg/30 mg Tablet

Avoid exceeding the recommended dose of Comcapsy 700 mg/30 mg Tablet , as it may lead to an overdose. Symptoms of an overdose may include nausea, vomiting, diarrhoea, stomach pain, unusual bleeding or bruising, weakness, tiredness, red-coloured urine, tarry stools, and signs of infection (fever, sore throat, cough). If you experience any of these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Comcapsy 700 mg/30 mg Tablet if you are allergic to any of its ingredients, fluorouracil, other cancer medicines, or have severe kidney disease or bladder obstruction. Tell your doctor if you are taking prescription or non-prescription medications, vitamins, or herbal supplements to rule out any side effects and interactions. Additionally, inform your doctor before taking Comcapsy 700 mg/30 mg Tablet if you had treatment with chemotherapy and radiation or have certain medical conditions, including metabolic disorders (such as dihydropyrimidine dehydrogenase deficiency), chronic infection, a weakened immune system, decreased bone marrow function (such as leukopenia, anaemia, thrombocytopenia), dehydration, urination problems, or heart, lung, liver, or kidney diseases. Tell your doctor if you are taking any blood thinners (warfarin) before using Comcapsy 700 mg/30 mg Tablet , as it may increase the risk of severe bleeding. Exercise caution when using sharp objects like nail cutters and razors to minimize the risk of injury or bruising. Avoid taking Comcapsy 700 mg/30 mg Tablet if you are pregnant or breastfeeding, as it may cause harmful effects on the baby. Use birth control pills while taking Comcapsy 700 mg/30 mg Tablet and for 6 months after your last dose to prevent pregnancy. Comcapsy 700 mg/30 mg Tablet should be used with caution in elderly patients over 60 years. Comcapsy 700 mg/30 mg Tablet may cause dizziness or vision problems, so avoid driving and operating machines until you are fully alert.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Comcapsy 700 mg/30 mg Tablet and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Nalidixic acid with Comcapsy 700 mg/30 mg Tablet may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Comcapsy 700 mg/30 mg Tablet and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Leflunomide with Comcapsy 700 mg/30 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Comcapsy 700 mg/30 mg Tablet can be taken with leflunomide if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Etanercept with Comcapsy 700 mg/30 mg Tablet may increase the risk or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Comcapsy 700 mg/30 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Folic acid with Comcapsy 700 mg/30 mg Tablet may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Folic acid and Comcapsy 700 mg/30 mg Tablet, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Comcapsy 700 mg/30 mg Tablet with Baricitinib may increase the risk of serious and potential infections.

How to manage the interaction:
Although there is an interaction, Comcapsy 700 mg/30 mg Tablet can be taken with Baricitinib if prescribed by the doctor. Consult the doctor if you develop fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Warfarin with Comcapsy 700 mg/30 mg Tablet can increase the effect of Warfarin.

How to manage the interaction:
Although there is a possible interaction between Comcapsy 700 mg/30 mg Tablet and Warfarin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
CapecitabineCertolizumab
Severe
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Comcapsy 700 mg/30 mg Tablet is taken with Certolizumab, which may increase the risk or severity of infections.

How to manage the interaction:
Although taking Comcapsy 700 mg/30 mg Tablet and Certolizumab together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Comcapsy 700 mg/30 mg Tablet is taken with Adalimumab, which may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between Comcapsy 700 mg/30 mg Tablet and Adalimumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include an enlarged spleen or liver, stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, complications, infection, fever, chills, diarrhea, a sore throat, muscle aches, difficulty breathing, or pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
How does the drug interact with Comcapsy 700 mg/30 mg Tablet:
Co-administration of Fingolimod with Comcapsy 700 mg/30 mg Tablet may increase the risk of serious and potential infections.

How to manage the interaction:
Although there is an interaction, Comcapsy 700 mg/30 mg Tablet can be taken with Fingolimod if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Incorporate leafy vegetables, fatty fish, citrus fruits, yogurt, berries, apples, cauliflower, peaches, cabbage, broccoli, beans, herbs, and spices into your diet.
  • Avoid fast foods, fried foods, processed meats, refined carbs, and added sugar.
  • Avoid smoking and excessive alcohol consumption.
  • Exercise at least 30 minutes on most days of the week.
  • Maintain a healthy weight and seek professional advice for weight loss.
  • Get enough sleep and rest for effective recovery.
  • Ask your doctor about when to start breast cancer screening and perform breast self-exams to notice any changes or lumps.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Comcapsy 700 mg/30 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

It is unknown whether alcohol interacts with Comcapsy 700 mg/30 mg Tablet . However, it is advisable not to consume alcohol as a precautionary measure.

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Pregnancy

Unsafe

Comcapsy 700 mg/30 mg Tablet should not be used during pregnancy, as it may cause harmful effects on the baby. You are advised to avoid pregnancy by using birth control pills during treatment with Comcapsy 700 mg/30 mg Tablet and for 6 months after your last dose.

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Breast Feeding

Unsafe

Comcapsy 700 mg/30 mg Tablet should not be taken during breastfeeding, as it passes into the breast milk and may harm the baby. You are advised to stop breastfeeding during treatment with Comcapsy 700 mg/30 mg Tablet and for 2 weeks after your last dose.

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Driving

Caution

Comcapsy 700 mg/30 mg Tablet may cause dizziness and vision problems. Therefore, avoid driving and operating machines until you are fully alert.

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Liver

Caution

Comcapsy 700 mg/30 mg Tablet may sometimes cause harm to the liver or increase bilirubin levels in the blood. If you have a history of liver disease, please inform your doctor before taking Comcapsy 700 mg/30 mg Tablet . Your doctor may need to adjust the dose of Comcapsy 700 mg/30 mg Tablet .

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Kidney

Caution

Comcapsy 700 mg/30 mg Tablet may sometimes cause harm to the kidney. If you have a history of kidney disease, please inform your doctor before taking Comcapsy 700 mg/30 mg Tablet . Your doctor may need to adjust the dose of Comcapsy 700 mg/30 mg Tablet .

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Children

Unsafe

Comcapsy 700 mg/30 mg Tablet should not be used by children under 12 years, as its safety and effectiveness have not been established in this age group.

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Heart

Please inform your doctor if you have a heart problem before using Comcapsy 700 mg/30 mg Tablet .

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Geriatrics

Consult your doctor

Please consult your doctor before giving Comcapsy 700 mg/30 mg Tablet to elderly people. Your doctor will prescribe Comcapsy 700 mg/30 mg Tablet if the benefits outweigh the risk.

FAQs

Comcapsy 700 mg/30 mg Tablet is an anticancer medication primarily used to treat metastatic breast cancer. It is also used in combination with other medicines to treat various types of cancer, as advised by a doctor, including colorectal, colon, stomach, pancreatic, and ovarian cancer.

Comcapsy 700 mg/30 mg Tablet contains two anticancer medications: Capecitabine (an antimetabolite) and Cyclophosphamide (an alkylating agent). Both drugs exhibit potential synergistic effects; Cyclophosphamide boosts the activity of an enzyme (thymidine phosphorylase) that helps convert Capecitabine into its active form, 5-fluorouracil. They work by damaging the genetic material of cancer cells to stop their growth and multiplication. Thus, Comcapsy 700 mg/30 mg Tablet helps treat cancer by killing cancer cells.

Comcapsy 700 mg/30 mg Tablet may cause common side effects such as nausea, vomiting, loss of appetite, diarrhoea, stomach pain, skin rash, weakness, tiredness, mouth sores, hair loss, fever, low blood cell count, and hand-foot syndrome (swelling, redness, and peeling on palms and soles). If you experience any of these side effects, do not hesitate to report them clearly to your doctor. Your doctor may suggest lifestyle changes, medications, and supportive therapies to help reduce discomfort and improve your quality of life.

Do not stop taking Comcapsy 700 mg/30 mg Tablet on your own without consulting your doctor, as it can affect your treatment and recovery. You are advised to take Comcapsy 700 mg/30 mg Tablet for as long as your doctor has prescribed it, depending on your medical condition, for effective treatment of cancer.

Yes, Comcapsy 700 mg/30 mg Tablet may impair fertility by temporarily stopping sperm production in men and disrupting normal menstrual periods in women. Therefore, consult your doctor for advice before taking Comcapsy 700 mg/30 mg Tablet if you are planning to have a child. Also, it is important to use birth control pills while taking Comcapsy 700 mg/30 mg Tablet and for 6 months after your last dose to prevent pregnancy.

Comcapsy 700 mg/30 mg Tablet might cause myelosuppression (reduced bone marrow function) leading to a decrease in white blood cells. This could lead to an increased risk of infections. You are advised to get regular blood tests while taking Comcapsy 700 mg/30 mg Tablet .

Yes, Comcapsy 700 mg/30 mg Tablet contains two chemotherapy medicines: Capecitabine, which is an antimetabolite, and Cyclophosphamide, which is an alkylating agent. They work by destroying cancer cells.

Comcapsy 700 mg/30 mg Tablet may cause weight loss due to decreased appetite and may also be a result of the underlying cancer. Please consult your doctor if you experience significant weight loss while using Comcapsy 700 mg/30 mg Tablet .

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - COM0668

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