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  3. Combitaz 250Mg Inj

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Combitaz 250Mg Inj, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Combitaz 250Mg Inj is used to treat various bacterial infections in the body. It contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, it helps to treat bacterial infections. Common side effects of this medication are redness and swelling at the injection site, headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, and muscle spasms.

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Composition :

CEFTAZIDIME-250MG + TAZOBACTAM-31.25MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Combitaz 250Mg Inj

Combitaz 250Mg Inj belongs to a class of medication called cephalosporin antibiotics. It is used to treat various bacterial infections in the body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

Combitaz 250Mg Inj contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Combitaz 250Mg Inj helps to treat bacterial infections.

Sometimes, you may experience redness and swelling at the injection site, headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, and muscle spasms. Most of these side effects of Combitaz 250Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking Combitaz 250Mg Inj, tell your doctor if you are pregnant or breastfeeding. Inform your doctor if you are allergic to any foods or medications. Drive with caution since Combitaz 250Mg Inj may cause dizziness. Before taking Combitaz 250Mg Inj, inform your doctor about your medical history and other medications you are currently taking in order to rule out any potential negative effects.

Uses of Combitaz 250Mg Inj

Combitaz 250Mg Inj is used in the treatment of serious bacterial infections, including those caused by resistant organisms in hospital settings. The detailed uses of Combitaz 250Mg Inj are as follows:<br/>• Treats respiratory infections: Combitaz 250Mg Inj is effective in managing severe pneumonia, including hospital-acquired cases.<br/>• Manages urinary tract infections: Combitaz 250Mg Inj is used for complicated UTIs, especially those involving resistant bacterial strains.<br/>• Controls skin and soft tissue infections: Combitaz 250Mg Inj is indicated for cellulitis, infected wounds, and abscesses.<br/>• Treats intra-abdominal infections: Combitaz 250Mg Inj is useful in the treatment of serious abdominal infections such as peritonitis.<br/>• Effective against hospital-acquired infections: Combitaz 250Mg Inj acts against multidrug-resistant bacteria, including ESBL-producing organisms commonly found in hospital settings.<br/>• Enhances antibacterial action: Combitaz 250Mg Inj provides a synergistic effect by inhibiting bacterial enzymes that break down antibiotics, thereby enhancing overall antibacterial activity against a wide range of gram-positive and gram-negative organisms.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Combitaz 250Mg Inj will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Combitaz 250Mg Inj contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the production of the bacterial cell wall (a protective covering required for survival). Tazobactam reduces bacterial resistance and increases the action of Ceftazidime against bacteria. Together, they aid in the treatment of bacterial infections, including serious, life-threatening infections due to gram-positive bacteria.

How Combitaz 250Mg Inj Works

Combitaz 250Mg Inj contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Combitaz 250Mg Inj helps to treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Combitaz 250Mg Inj out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Combitaz 250Mg Inj

As Combitaz 250Mg Inj is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of Combitaz 250Mg Inj may include muscle stiffness, uncontrolled muscle movements, seizure, or coma.

Drug Warnings

Before taking the Combitaz 250Mg Inj, inform your doctor about all your medical conditions, sensitivities, and all medications (including herbals and supplements) you are using. If you are pregnant or breastfeeding, inform your doctor before taking Combitaz 250Mg Inj. You are recommended to complete the full course of Combitaz 250Mg Inj as your doctor prescribes for effective results. Combitaz 250Mg Inj should not be administered if you are currently on any vaccinations or are scheduled for the same. Combitaz 250Mg Inj should be used with caution in those with Clostridium difficile-associated diarrhoea. Drive only if you are alert, as Combitaz 250Mg Inj may cause dizziness.

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Combitaz 250Mg Inj to restore some healthy intestinal bacteria that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after an antibiotic course. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
  • Avoid taking much calcium-enriched foods and drinks as it might affect the working of Combitaz 250Mg Inj.
    Avoid intake of alcoholic beverages with Combitaz 250Mg Inj as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Combitaz 250Mg Inj in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

The interaction of Combitaz 250Mg Inj with alcohol is unknown. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

The safety of Combitaz 250Mg Inj in pregnant women is unknown. Therefore, please inform your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Consult the doctor if you are breastfeeding. Consider the importance of the medicine to the mother when deciding whether to discontinue nursing or the medicine.

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Driving

Caution

Combitaz 250Mg Inj may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Combitaz 250Mg Inj.

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Liver

Caution

Take Combitaz 250Mg Inj with caution, especially if you have a history of liver diseases. Inform your doctor before receiving the Combitaz 250Mg Inj if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Take Combitaz 250Mg Inj with caution, especially if you have a history of kidney diseases. Inform your doctor before receiving the Combitaz 250Mg Inj if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Limited information is available regarding the usage of Combitaz 250Mg Inj in children, so please consult a doctor if you have any concerns.

FAQs

Combitaz 250Mg Inj is used to treat Bacterial infections.

Ceftazidime and Tazobactam are both present in Combitaz 250Mg Inj. Ceftazidime works by preventing the production of the bacterial cell wall (a protective covering required for survival). Tazobactam reduces bacterial resistance while increasing the efficacy of Ceftazidime against bacteria. Together, Combitaz 250Mg Inj aids in the treatment of bacterial illnesses.

Combitaz 250Mg Inj may Increase liver enzymes. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Combitaz 250Mg Inj.

Combitaz 250Mg Inj may cause diarrhoea as a common side effect. However, if the condition persists or worsens, consult a doctor immediately.

If you are being treated with Combitaz 250Mg Inj or have been treated within the last three days, you should talk to your doctor before taking the vaccine. Antibiotics like Combitaz 250Mg Inj can reduce the vaccine&#039;s activity.

Combitaz 250Mg Inj usually begins to work shortly after you start taking it. However, it may take a few days to eliminate all harmful bacteria and improve your symptoms.

If you do not get better after using Combitaz 250Mg Inj, reach out to your doctor immediately. They might re-evaluate your condition, investigate potential issues, and modify your treatment accordingly.

Combitaz 250Mg Inj causes side effects such as headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, muscle spasm, and elevated liver enzymes. Contact a doctor if these side effects persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Other Info - COM0114

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:07 AM IST

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Reference

  1. https://www.drugs.com/drug-interactions/ceftazidime-index.html?filter=3
  2. https://www.drugs.com/drug-interactions/tazobactam.html
  3. https://www.arlakbiotech.com/product/torzid-t-inj/
  4. https://www.medicines.org.uk/emc/files/pil.275.pdf

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