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compositionComposition:IBUPROFEN-200MG+PARACETAMOL-325MG
prescriptionPrescription Medicine
Combitab Tablet 15's

Combitab Tablet 15's is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever. It contains Ibuprofen and Paracetamol, which work by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. It may cause side effects such as tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate and or in case of any signs of hypersensitivity. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IBUPROFEN-200MG+PARACETAMOL-325MG

Manufacturer/Marketer :

Sunlife Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Combitab Tablet 15's

Combitab Tablet 15's is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever. Pain can be temporary (acute) or long-lasting (chronic).

Combitab Tablet 15's contains Ibuprofen and Paracetamol. This medicine works by blocking the effect of prostaglandin, which is responsible for inducing pain and inflammation in the body.

Like all medicines, Combitab Tablet 15's may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, or any signs of hypersensitivity.

Inform your doctor if you are allergic to any of the components present in it. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Avoid consumption of alcohol as it may damage your liver and cause increased side effects on taking this drug.

Uses of Combitab Tablet 15's

Combitab Tablet 15's is used for the treatment of Pain and Fever. The detailed uses of Combitab Tablet 15's are as follows:

  • Pain Relief: Combitab Tablet 15's is widely used to alleviate mild to moderate pain, such as headaches, toothaches, menstrual cramps, and muscle aches.
  • Fever Reduction: Combining Ibuprofen and Paracetamol, Combitab Tablet 15's effectively reduces fever caused by infections or other health conditions.
  • Anti-inflammatory Benefits: Its anti-inflammatory properties make Combitab Tablet 15's valuable for managing inflammation and swelling in conditions like arthritis and other inflammatory diseases.
  • Post-Surgical Pain Management: Combitab Tablet 15's is often prescribed to manage pain and discomfort following surgical procedures, aiding recovery.
  • Managing Chronic Pain: Combitab Tablet 15's is sometimes included in chronic pain management plans, particularly for conditions like osteoarthritis or persistent back pain, under a healthcare professional's supervision.

Key Benefits

  • Combitab Tablet 15's is prescribed mainly to treat pain and relieve discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains.
  • Combitab Tablet 15's comprises Ibuprofen and Paracetamol, primarily used to treat mild to moderate pain.
  • Ibuprofen works by blocking the effect of a chemical known as prostaglandin, which is responsible for inducing pain and inflammation in the body.
  • Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of prostaglandin by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat.
  • Paracetamol has the advantage of producing less gastric irritation than other painkillers like aspirin.
Side effects of Combitab Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink fluids: Water, clear broth, or electrolyte-rich beverages.
  • Follow a balanced diet, which would be rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.
  • Mindfulness: Manage stress with meditation, deep breathing or yoga.
  • Stay away from smoke, dust and other irritants.
  • Get adequate rest to facilitate recovery.
  • Wash hands and avoid close contact, do not share personal items.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.

Directions for Use

  • Combitab Tablet 15's should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Combitab Tablet 15's as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Combitab Tablet 15's Works

Combitab Tablet 15's is composed of two medicines, namely Ibuprofen and Paracetamol. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together, these two medicines help reduce mild to moderate pain in a shorter duration.
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Alcohol

Unsafe

Taking Combitab Tablet 15's with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Combitab Tablet 15's.

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Pregnancy

Unsafe

Use of Combitab Tablet 15's during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

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Breast Feeding

Consult your doctor

Take Combitab Tablet 15's only if prescribed by your doctor.

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Driving

Unsafe

After taking Combitab Tablet 15's you may notice dizziness, sleepiness, drowsiness or fatigue.

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Liver

Caution

Combitab Tablet 15's to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Combitab Tablet 15's to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Combitab Tablet 15's is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

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Heart

Unsafe

Combitab Tablet 15's should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

Combitab Tablet 15's should be used under caution in geriatric patients as it can lead to serious side effects.

What if I have taken an overdose of Combitab Tablet 15's

Do not take more than the prescribed dose of Combitab Tablet 15's as it may cause severe side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic exercises like walking on the treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Have a query?

How Soon It Starts Working

The time required for Combitab Tablet 15's to start to work: The time required for Combitab Tablet 15's to show its action is unknown. 

The time for which the effects of Combitab Tablet 15's last: The duration of action for Combitab Tablet 15's is unknown.

What if you forget to take Combitab Tablet 15's

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Caution is advised in people with underlying sensitivity to aspirin and other painkillers.
  • Combitab Tablet 15's is contraindicated in children below 12 years of age, weighing under 40 kg.
  • If treatment is required for more than three days, consult your doctor.
  • Combitab Tablet 15's should be taken with caution if you have an allergy to paracetamol, ibuprofen, aspirin, or other pain killers, highly sensitive reactions (asthma, lip/face/throat swelling), existing stomach ulcer or bleeding associated pain killers, blood clotting disorder, heart diseases (like congestive heart failure), kidney disease, peptic ulcer, another active bleeding (like brain stroke bleeding), and severe dehydration (due to vomiting, diarrhea).
  • Liver damage might occur if taken for a longer duration, as it contains paracetamol.
  • The skin should be closely monitored as skin allergic reactions like Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) have been reported with Combitab Tablet 15's.
  • Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Combitab Tablet 15's, especially in people affected with high blood pressure and who have a history of heart failure.
  • Consult your doctor if your pain, inflammation, and fever symptoms do not disappear even after ten days.

Drug-Drug Interactions

verifiedApollotooltip

Drug Interactions: Combitab Tablet 15's is shown to interact with various drugs. Some of them include lithium, blood thinner or anticoagulant (warfarin, ticlopidine), anti-arthritis pills (methotrexate), blood pressure or heart medicine, nausea/vomiting medicine (metoclopramide, domperidone), diuretic/water pills (thiazides, furosemide), steroid medicine (prednisone), quinolones antibiotics (ciprofloxacin), respiratory medicines (theophylline, ephedrine), cholesterol-reducing medicine (colestyramine) and antidepressants (duloxetine). These drugs may affect the working of Combitab Tablet 15's and may alter its efficacy.

Drug-Food Interactions: Combitab Tablet 15's interacts with alcoholic beverages and increases your risk of stomach bleeding.

Drug-Disease Interactions: Combitab Tablet 15's should not be recommended for people having the liver disease (like Gilbert’s syndrome in which the liver does not process bile), asthma, allergic skin diseases (Stevens-Johnson syndrome, toxic epidermal necrolysis), blood clot disorder, high blood pressure (hypertension), or history of heart failure. Besides this, Combitab Tablet 15's should not be given to the children suffering from influenza (flu) or chickenpox. It should also be avoided in case of the presence of gastric/duodenal ulcers and low glutathione levels.

Ibuprofen + ParacetamolMeloxicam
Critical
Ibuprofen + ParacetamolKetorolac
Critical

Drug-Drug Interactions

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Ibuprofen + ParacetamolMeloxicam
Critical
How does the drug interact with Combitab Tablet:
Coadministration of meloxicam and ibuprofen can increase the risk of side effects such as inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between meloxicam and ibuprofen, it can be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolKetorolac
Critical
How does the drug interact with Combitab Tablet:
Taking ketorolac with ibuprofen can increase the risk of side effects in inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between ketorolac and ibuprofen, it can be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolMipomersen
Severe
How does the drug interact with Combitab Tablet:
Co-administration of mipomersen with ibuprofen may increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between ibuprofen and mipomersen, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolDanaparoid
Severe
How does the drug interact with Combitab Tablet:
Coadministration of danaparoid and ibuprofen can increase the risk of bleeding complications.

How to manage the interaction:
Although there is an interaction between danaparoid and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolDasatinib
Severe
How does the drug interact with Combitab Tablet:
Coadministration of dasatinib and ibuprofen can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between dasatinib and ibuprofen, it can be taken if advised by your doctor. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolTeriflunomide
Severe
How does the drug interact with Combitab Tablet:
Coadministration of teriflunomide and ibuprofen can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between teriflunomide and ibuprofen, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolTacrolimus
Severe
How does the drug interact with Combitab Tablet:
Taking tacrolimus and ibuprofen can cause kidney problems.

How to manage the interaction:
Although there is an interaction between tacrolimus and ibuprofen, it can be taken if advised by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolIndometacin
Severe
How does the drug interact with Combitab Tablet:
Coadministration of indometacin and ibuprofen can increase the risk of inflammation, stomach ulcers, and bleeding complications.

How to manage the interaction:
Although there is an interaction between indometacin and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolOmacetaxine mepesuccinate
Severe
How does the drug interact with Combitab Tablet:
Coadministration of omacetaxine mepesuccinate and ibuprofen can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between omacetaxine mepesuccinate and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolFlurbiprofen
Severe
How does the drug interact with Combitab Tablet:
Coadministration of flurbiprofen and ibuprofen can increase the risk of ulcers, inflammation and bleeding complications.

How to manage the interaction:
Although there is an interaction between flurbiprofen and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

Combitab Tablet 15's is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever.

Combitab Tablet 15's is comprised of two medications, Ibuprofen and Paracetamol. Combitab Tablet 15's has analgesic and anti-inflammatory properties that help relieve mild to moderate pain. Combitab Tablet 15's functions by inhibiting the production of specific chemical messengers that induce fever, discomfort, and inflammation (redness and swelling).

No, it is not advisable to take Combitab Tablet 15's with depression medication. Please inform your doctor if you are taking depression medicine before starting Combitab Tablet 15's.

Yes, Combitab Tablet 15's is a short term medication and if you feel better you can stop taking Combitab Tablet 15's, but only after consulting your doctor.

Combitab Tablet 15's is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.

Yes, Combitab Tablet 15's is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take Combitab Tablet 15's as it can be harmful.

No, Combitab Tablet 15's is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer, or gastric bleeding. Do not take Combitab Tablet 15's in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.

It depends on whether your cough and cold pills contain ibuprofen and paracetamol or not. If it contains these two medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

Combitab Tablet 15's is known to cause stomach upset in some cases. So, please take Combitab Tablet 15's with a meal or a glass of milk to avoid upset stomach.

No, Combitab Tablet 15's should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Combitab Tablet 15's, please take it in doses and duration mentioned by your doctor.

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

Sunlife Sciences Pvt Ltd
Other Info - COM0843
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