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Reviewed By Santoshini Reddy G , M Pharmacy

Combimist LD Respule 5X2.5 ml is used to treat or prevent symptoms of chronic obstructive pulmonary disease (COPD), like shortness of breath, coughing or wheezing (whistling sound while breathing). It contains Levosalbutamol and Ipratropium bromide, which work by relaxing muscles and widening the airways of the lungs. Some people may experience headache, sore throat, dry mouth, runny or stuffy nose, cough with mucus, and vomiting. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Bayer Zydus Pharma Pvt Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Combimist LD Respule 5X2.5 ml

Combimist LD Respule 5X2.5 ml is used to treat or prevent symptoms of chronic obstructive pulmonary disease (COPD), like shortness of breath, coughing or wheezing (whistling sound while breathing).

Combimist LD Respule 5X2.5 ml is a combination of two bronchodilators: Levosalbutamol and Ipratropium bromide, which work by relaxing muscles and widening the airways of the lungs. Thereby, it makes breathing easier.

Some people may experience headache, sore throat, dry mouth, runny or stuffy nose, nausea and vomiting. Most of these side effects of Combimist LD Respule 5X2.5 ml do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Combimist LD Respule 5X2.5 ml or any other medicines, are pregnant or breastfeeding, please consult a doctor. Keep your doctor informed about your health condition and medications to prevent any potential interactions. 

Uses of Combimist LD Respule 5X2.5 ml

Combimist LD Respule 5X2.5 ml is used to treat chronic obstructive pulmonary disease (COPD). The detailed uses of Combimist LD Respule 5X2.5 ml are as follows:

  • Chronic Obstructive Pulmonary Disease (COPD): Combimist LD Respule 5X2.5 ml is used to treat COPD symptoms by improving lung function and relieving chronic cough and breathing difficulties.
  • Prevention of Exercise-Induced Bronchospasm: Combimist LD Respule 5X2.5 ml helps to prevent exercise-induced bronchospasm, enabling easier breathing during physical activity.
  • Reduce Mucus Clearance: Combimist LD Respule 5X2.5 ml helps to thin mucus, making it easier to clear from airways, which improves breathing and respiratory function.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use as advised by the doctor. Twist off the top of the respule and squeeze the solution into the nebuliser. This solution is formulated into a fine mist for inhalation. Inhale the medicine through the nebuliser's mouthpiece.
  • The respule should be opened only before actual use, and any solution remaining after use should be discarded.
  • To prevent any fungal infections in your mouth and throat, gargle with warm water after each inhalation.

Medicinal Benefits

  • Combimist LD Respule 5X2.5 ml is a combination of two bronchodilators: Levosalbutamol and Ipratropium bromide, used to treat chronic obstructive pulmonary disease (COPD).
  • It relaxes the airway muscles and widens the air passages in the lungs. This action improves airflow to the lungs and makes breathing easier.
  • Combimist LD Respule 5X2.5 ml provides quick and sustained relief from respiratory symptoms like shortness of breath, wheezing, and coughing.
  • The dual action of both components makes it more effective than either medicine alone in managing moderate to severe COPD symptoms.

How Combimist LD Respule 5X2.5 ml Works

Combimist LD Respule 5X2.5 ml is a combination of two bronchodilators: Levosalbutamol and Ipratropium bromide. It works by relaxing muscles and widening the airways of the lungs. Thereby, Combimist LD Respule 5X2.5 ml makes breathing easier.

Storage

• Store in a cool and dry place away from sunlight.• Keep Combimist LD Respule 5X2.5 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Combimist LD Respule 5X2.5 ml
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Consult your doctor to identify the medication causing abnormal contractions of your gut, and consider reducing the dosage or switching to alternative drugs with fewer side effects.
  • Your doctor may recommend medications to help with your symptoms, like anticholinergics, antispasmodics, or prokinetic agents.
  • Avoid foods high in fibre, like oranges and broccoli, as they may cause a blockage in your gut.
  • Gradually add more fibre to your diet by eating vegetables, whole grains, fruits, and beans to help improve your bowel movements.
  • Eat smaller meals throughout the day to reduce stress on your digestive system.
  • Choose low-fat foods and cook fruits and vegetables well to make them easier to digest.
  • Drink lots of water or other fluids to help with your digestion.
  • Try moderate exercise and stress-relief activities like deep breathing or meditation to help keep your gut running smoothly.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Combimist LD Respule 5X2.5 ml

Do not use Combimist LD Respule 5X2.5 ml in more doses or more often than prescribed, as it may cause unpleasant side effects. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not use Combimist LD Respule 5X2.5 ml if you are allergic to any of its components.
  • If you are pregnant or breastfeeding, please consult a doctor before starting Combimist LD Respule 5X2.5 ml.
  • Combimist LD Respule 5X2.5 ml may cause low potassium levels. If you experience irregular heartbeats, leg cramps, extreme thirst, constipation, increased urination, muscle weakness, numbness or tingling, please consult a doctor immediately, as these might be signs of low potassium.
  • If you have high blood pressure, diabetes, epilepsy (fits), enlarged prostate, glaucoma, thyroid or heart problems, bladder obstruction or other urinary problems, inform your doctor before taking Combimist LD Respule 5X2.5 ml.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Combimist LD Respule 5X2.5 ml:
When Combimist LD Respule 5X2.5 ml is used in combination with Labetalol, the therapeutic effectiveness of Combimist LD Respule 5X2.5 ml can be decreased which may lead to low treatment outcomes.

How to manage the interaction:
Taking Combimist LD Respule 5X2.5 ml with Labetalol may lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combimist LD Respule 5X2.5 ml:
Coadministration of Carvedilol and Combimist LD Respule 5X2.5 ml may reduce the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Combimist LD Respule 5X2.5 ml and Carvedilol, it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Combimist LD Respule 5X2.5 ml:
Taking Combimist LD Respule 5X2.5 ml with Cocaine may cause irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction, Combimist LD Respule 5X2.5 ml can be taken with Cocaine if prescribed by the doctor. Do not discontinue the medications without consulting doctor.
How does the drug interact with Combimist LD Respule 5X2.5 ml:
Coadministration of propranolol and Combimist LD Respule 5X2.5 ml can increase the risk of breathing problems.

How to manage the interaction:
Although there is an interaction between propranolol and Combimist LD Respule 5X2.5 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Combimist LD Respule 5X2.5 ml:
Coadministration of Sotalol and Combimist LD Respule 5X2.5 ml may decrease the bronchodilatory activities of Combimist LD Respule 5X2.5 ml.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Combimist LD Respule 5X2.5 ml, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combimist LD Respule 5X2.5 ml:
Taking Combimist LD Respule 5X2.5 ml with levalbuterol may reduce the benefits of both medications.

How to manage the interaction:
Although there is a possible interaction, Combimist LD Respule 5X2.5 ml can be taken with Levobunolol if prescribed by the doctor. Do not discontinue the medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in potassium, such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots, as potassium is important for lung function and a potassium deficiency may cause breathing problems.
  • Drink plenty of fluids every day to thin mucus, which makes it easier to cough out.
  • Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas, and potatoes with skin.
  • Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks.
  • Eat protein-rich foods such as meat, fish (particularly salmon, sardines, and mackerel), eggs, and poultry.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.
  • Quit smoking as it may irritate the lungs, worsening breathing problems.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR
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Alcohol

Consult your doctor

The interaction of Combimist LD Respule 5X2.5 ml with alcohol is unknown. Please consult a doctor before consuming alcohol with Combimist LD Respule 5X2.5 ml.

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Pregnancy

Consult your doctor

The safety of Combimist LD Respule 5X2.5 ml in pregnant women is unknown. Please consult your doctor if you are pregnant. It is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Combimist LD Respule 5X2.5 ml is excreted in human milk. Please consult your doctor if you are breastfeeding. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Combimist LD Respule 5X2.5 ml may cause blurred vision or dizziness in some people. Therefore, avoid driving if you notice any changes in vision or feel dizzy after taking Combimist LD Respule 5X2.5 ml.

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Liver

Caution

Combimist LD Respule 5X2.5 ml should be used with caution in patients with liver impairment. If you have any concerns regarding the use of Combimist LD Respule 5X2.5 ml in patients with liver problems, please consult a doctor.

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Kidney

Caution

Dose adjustment may be needed. If you have any concerns regarding the use of Combimist LD Respule 5X2.5 ml in patients with kidney problems, please consult a doctor.

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Children

Consult your doctor

The safety of Combimist LD Respule 5X2.5 ml in children below 12 years is unknown. Please consult a doctor before giving Combimist LD Respule 5X2.5 ml to children.

Have a query?

FAQs

Combimist LD Respule 5X2.5 ml is used to treat or prevent symptoms of chronic obstructive pulmonary disease (COPD), like shortness of breath, coughing or wheezing (whistling sound while breathing).

Combimist LD Respule 5X2.5 ml is a combination of two bronchodilators: Levosalbutamol and Ipratropium bromide. It works by relaxing muscles and widening the airways of the lungs. Thereby, Combimist LD Respule 5X2.5 ml makes breathing easier.

Combimist LD Respule 5X2.5 ml should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Combimist LD Respule 5X2.5 ml as it may increase blood sugar levels.

Combimist LD Respule 5X2.5 ml should be used with caution in hyperthyroid (overactive thyroid) patients as it may worsen the condition. Inform your doctor if you have hyperthyroidism before taking Combimist LD Respule 5X2.5 ml so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while taking Combimist LD Respule 5X2.5 ml.

Yes, Combimist LD Respule 5X2.5 ml may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Combimist LD Respule 5X2.5 ml to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

No, Combimist LD Respule 5X2.5 ml does not relieve sudden symptoms such as shortness of breath. Therefore, it is advised to carry a rescue inhaler always to treat sudden symptoms.

Combimist LD Respule 5X2.5 ml may cause side effects such as headache, sore throat, dry mouth, and respiratory issues like cough, sneezing, and difficulty breathing. Other possible side effects include dizziness, nervousness, tiredness, irregular heartbeats, and vomiting. In most cases, these side effects are temporary and resolve on their own. However, if they persist or worsen, it's essential to consult your doctor for proper guidance.

No, you are not recommended to stop using Combimist LD Respule 5X2.5 ml without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Combimist LD Respule 5X2.5 ml for as long as your doctor has prescribed it, and if you experience any difficulty while taking Combimist LD Respule 5X2.5 ml, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Bayer Ag, Mã¼Llerstr. 178, 13353 Berlin
Other Info - COM0657

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