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compositionComposition:AMITRIPTYLINE-10MG+PROPRANOLOL-40MG
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Prescription Medicine
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Cobaleo Beta-10 Tablet 10's is a tricyclic antidepressant used in the prevention of migraine attacks with co-morbid conditions like insomnia, neuralgic pain, hypertension, and anxiety. This combination medicine increases serotonin levels and decreases electrical activity in the brain, thereby helping to relieve your symptoms of pain or migraine. Common side effects include weight gain, dry mouth, blurred vision, increased intraocular pressure, constipation, sedation and drowsiness, hypotension, etc.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

AMITRIPTYLINE-10MG+PROPRANOLOL-40MG

Manufacturer/Marketer :

Win Life Science Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Cobaleo Beta-10 Tablet 10's

Cobaleo Beta-10 Tablet 10's is a combination prescription medicine used primarily to prevent chronic migraines and tension-type headaches. It helps reduce the frequency and severity of these painful attacks, especially when they are accompanied by anxiety or stress. This medication is designed for ongoing prevention rather than treating a headache that has already started.

To get the most benefit, you must take Cobaleo Beta-10 Tablet 10's consistently every day, even when you feel completely fine. It is typically taken once daily, usually in the evening because it can make you feel sleepy. You can take this tablet with or without food, but keeping your routine consistent is key to maintaining steady levels of the medicine in your body. Making simple changes like keeping a regular sleep schedule and avoiding dietary headache triggers can significantly boost the effectiveness of your treatment.

While taking Cobaleo Beta-10 Tablet 10's, you may experience some common side effects like a dry mouth, sleepiness, or mild tiredness. Most of these are mild and improve as your body adjusts, but you must contact your doctor immediately if you experience severe symptoms such as a very slow heart rate, difficulty breathing, or sudden changes in your mood.

Before starting this medication, tell your doctor if you have a history of heart conditions, diabetes, liver damage, or thyroid problems. Do not take this if you have asthma, a slow heart rate, or if you have recently had a heart attack. Your doctor will help determine if this is the safest treatment option for your specific medical history.

This medicine can interact with alcohol, which increases drowsiness, and smoking, which can reduce how well the treatment works. It also interacts with certain blood pressure medications and other antidepressants, which is why sharing a complete list of your current medicines with your healthcare provider is vital. If you are pregnant, breastfeeding, or an older adult, consult your doctor before starting Cobaleo Beta-10 Tablet 10's to ensure it is safe for you.

Uses of Cobaleo Beta-10 Tablet 10's

Cobaleo Beta-10 Tablet 10's may be used to help manage the following conditions:

  • Prevention of migraines: Cobaleo Beta-10 Tablet 10's helps reduce how often you get migraine attacks and makes them less severe by calming overactive nerves and relaxing blood vessels in the brain.
  • Management of tension headaches: It helps ease chronic daily head pain by relaxing tight muscles and reducing pain signals in the nervous system.
  • Relief of neuropathic pain with anxiety: It targets nerve-related discomfort while simultaneously relieving the physical symptoms of anxiety and tension.

Key Benefits

Cobaleo Beta-10 Tablet 10's is used to help prevent migraine headaches. It works by reducing the frequency and severity of migraine attacks while also helping relieve associated symptoms such as stress and tension.

  • Helps Prevent Migraines: Reduces the frequency and severity of migraine attacks, helping improve day-to-day functioning.
  • Reduces Headache Burden: Helps decrease the number of headache days, allowing you to carry out daily activities with greater comfort.
  • Promotes Better Sleep: Amitriptyline may improve sleep quality, which can help reduce migraine triggers and improve overall well-being.
  • Helps Reduce Physical Symptoms of Stress: Propranolol helps control physical symptoms such as a fast heartbeat and tremors, which may contribute to migraine attacks in some people.
  • Improves Quality of Life: Regular use as prescribed may help you maintain a more active lifestyle with fewer interruptions from migraine episodes.
Side effects of Cobaleo Beta-10 Tablet
Managing Medication-Triggered Productive cough (wet cough): A Step-by-Step Guide:
  • If you experience a persistent cough after taking medication, consult your doctor to determine the best course of action.
  • Your doctor will assess and adjust your medication regimen if necessary to minimize the cough.
  • Your doctor may recommend cough medications, such as expectorants, to help loosen and clear mucus.
  • Stay hydrated by drinking plenty of fluids, and consider a soothing lifestyle, such as a warm, humid environment, avoiding irritants like smoke and dust, and getting plenty of rest.
  • If your cough persists or worsens, follow up with your doctor for further evaluation and treatment.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Keep regular sleeping hours.
  • Don’t consume nicotine, caffeine, or alcohol in the hours leading up to bed.
  • Practice relaxation exercises before bedtime.
  • Regular physical activity can promote deeper and better sleep. However, avoid intense exercise within 2-3 hours of bedtime, as it can disrupt your sleep.
  • If nightmares continue, cognitive behavioral therapy (CBT) may be a helpful treatment option. Your doctor may recommend CBT to address underlying issues and provide coping strategies to manage nightmares.

Directions for Use

  • Cobaleo Beta-10 Tablet 10's can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Cobaleo Beta-10 Tablet 10's as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Cobaleo Beta-10 Tablet 10's Works

Cobaleo Beta-10 Tablet 10's contains amitriptyline and propranolol. It is a combination medicine that contains two active ingredients working together to help prevent migraine headaches. The first active ingredient, propranolol, belongs to a class of medicines called beta-blockers. It works by blocking the effects of stress hormones such as adrenaline on beta receptors. This helps reduce overactivity in the nervous system, stabilise nerve signalling, and lower the likelihood of the changes in the brain that can trigger migraine attacks. The second active ingredient, amitriptyline, is a tricyclic antidepressant. It works by blocking the reuptake of natural chemical messengers called serotonin and norepinephrine, increasing their availability in the brain. These chemicals help regulate pain signals, reduce nerve sensitivity, and may also improve sleep and relieve anxiety, all of which can contribute to migraine prevention. Together, these two active ingredients help reduce the frequency and severity of migraine attacks by acting on different pathways involved in migraine development.
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Alcohol

Caution

Avoid consuming alcohol when taking the Cobaleo Beta-10 Tablet 10's as it may cause excessive drowsiness.

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Pregnancy

Caution

There is limited data on how Cobaleo Beta-10 Tablet 10's affects pregnancy. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Cobaleo Beta-10 Tablet 10's.

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Breast Feeding

Caution

Consult your doctor; there is no substantial research yet on using Cobaleo Beta-10 Tablet 10's in breastfeeding/nursing mothers.

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Driving

Caution

Cobaleo Beta-10 Tablet 10's causes blurred vision and hypotension. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Cobaleo Beta-10 Tablet 10's to be taken with caution, especially if you have a history of Liver diseases/conditions. Please consult the doctor; your doctor will weigh the benefits and potential risks before prescribing Cobaleo Beta-10 Tablet 10's.

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Kidney

Caution

Cobaleo Beta-10 Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. Please consult the doctor; your doctor will weigh the benefits and potential risks before prescribing Cobaleo Beta-10 Tablet 10's.

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Children

Unsafe

The safety and efficacy of Cobaleo Beta-10 Tablet 10's in children have not been established.

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Heart

Caution

Cobaleo Beta-10 Tablet 10's should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Cobaleo Beta-10 Tablet 10's.

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Geriatrics

Caution

Cobaleo Beta-10 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. Please talk to your doctor before use.

What if I have taken an overdose of Cobaleo Beta-10 Tablet 10's

If you suspect an overdose, seek immediate medical attention or call emergency services right away. Symptoms of an overdose may include severe drowsiness, an extremely slow or rapid heartbeat, confusion, cold or clammy skin, and fainting.

Diet & Lifestyle Advise

  • Keep a Headache Diary: Record your headaches, meals, sleep, stress levels, and possible triggers to help identify and avoid migraine triggers.
  • Maintain a Regular Sleep Schedule: Go to bed and wake up at the same time every day, as irregular sleep patterns may trigger migraines.
  • Stay Well-Hydrated: Drink plenty of water throughout the day to help prevent dehydration, a common migraine trigger.
  • Exercise Regularly: Engage in moderate physical activity, such as walking, swimming, or yoga, to help reduce stress and promote overall health.
  • Avoid Skipping Meals: Eat regular, balanced meals to help maintain stable blood sugar levels and reduce the risk of migraine attacks.
health query

Have a query?

How Soon It Starts Working

The time required for Cobaleo Beta-10 Tablet 10's to start to work: The time required for Cobaleo Beta-10 Tablet 10's to show its action is unknown. The time for which the effects of Cobaleo Beta-10 Tablet 10's last: The duration of action for Cobaleo Beta-10 Tablet 10's is clinically unknown.

What if you forget to take Cobaleo Beta-10 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Cobaleo Beta-10 Tablet 10's tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Do Not Stop the Medicine Suddenly: Do not discontinue Cobaleo Beta-10 Tablet 10's without consulting your doctor, as sudden withdrawal may worsen symptoms or cause rebound effects.
  • Avoid Driving Until You Know Its Effects: This medicine may cause drowsiness, dizziness, or slowed reactions. Do not drive or operate machinery until you know how it affects you.
  • Stand Up Slowly: Rise gradually from sitting or lying positions to reduce the risk of dizziness or fainting caused by a drop in blood pressure.
  • Inform Healthcare Providers Before Procedures: Tell your doctor, dentist, or surgeon that you are taking Cobaleo Beta-10 Tablet 10's before any medical, dental, or surgical procedure.
  • Monitor Your Heart Rate and Blood Pressure: Check your pulse and blood pressure regularly if advised by your doctor, and report unusually slow heart rates or low blood pressure readings promptly.

Drug-Drug Interactions

verifiedApollotooltip

Cobaleo Beta-10 Tablet 10's may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.

  • Sleeping pills, anxiety medicines, and muscle relaxants: May cause extreme, dangerous drowsiness and slowed breathing when taken with Cobaleo Beta-10 Tablet 10's.
  • Other blood pressure medications: May cause your blood pressure to drop too low, resulting in dizziness or fainting.
  • Monoamine oxidase inhibitors (MAOIs): Can cause a dangerous, life-threatening rise in blood pressure and body temperature. Always wait at least 14 days after stopping an MAOI before starting Cobaleo Beta-10 Tablet 10's.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may interact with Cobaleo Beta-10 Tablet 10's and affect how it works or increase the risk of side effects.

  • Alcohol: Significantly increases the risk of severe drowsiness, dizziness, and poor coordination.
  • Grapefruit juice: May interfere with how your body breaks down this medicine, potentially increasing its side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Cobaleo Beta-10 Tablet 10's belongs to a group of medicines called tricyclic anti-depressants used to prevent migraine attacks with co-morbid conditions like insomnia, neuralgia pain, hypertension, and anxiety.
Cobaleo Beta-10 Tablet 10's contains amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change the way that your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
Amitriptyline in Cobaleo Beta-10 Tablet 10's may cause decreased sex drive and problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.
Cobaleo Beta-10 Tablet 10's may cause dry mouth as an adverse effect. Limiting caffeine intake, avoiding smoking and alcohol-containing mouthwashes, drinking plenty of water, and eating sugar-free gum/candy may help promote saliva and prevent mouth drying.
There is no indication that Cobaleo Beta-10 Tablet 10's impacts male or female fertility. Consult your doctor if you are trying to conceive or have difficulty conceiving while taking Cobaleo Beta-10 Tablet 10's.
Yes, sleepiness and fatigue are very common, especially when you first start taking this medicine. To help manage this, it is usually recommended to take your dose in the evening or at bedtime. If daytime drowsiness remains severe or interferes with your daily safety, talk to your doctor.
High amounts of caffeine can trigger migraines or make them worse, and can also interfere with the calming effects of Cobaleo Beta-10 Tablet 10's. It is best to limit your caffeine intake to a moderate, consistent level. Talk to your doctor or pharmacist about your dietary habits.
Cobaleo Beta-10 Tablet 10's is generally not recommended during pregnancy or breastfeeding unless your doctor decides that the medical benefit is absolutely necessary. The active ingredients can pass into breast milk and may affect a developing baby. Talk to your doctor immediately if you are pregnant or planning a pregnancy.
Take the missed dose as soon as you remember. If it is already close to the time for your next dose, skip the missed one and continue with your normal schedule. Do not take two doses at the same time to make up for a missed dose. If you frequently miss doses, talk to your doctor or pharmacist for tips on staying on track.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Gf- 1, Jay Yogeshwar Soc, Navjivan Ajwa Road, Vadodara, Gujarat, 390025, India
Other Info - COB0367

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