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  3. Co-Sdr Cap 10'S

Co-Sdr Cap 10'S, Pack of 10 CAPSULES
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Co-SDR Capsule is used to treat nausea and vomiting in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. It contains Domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time. The most common side effect of this medicine is dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DOMPERIDONE-30MG

Manufacturer/Marketer :

Curo Prime Pharmax Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Co-SDR Capsule

Co-SDR Capsule is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

Co-SDR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Co-SDR Capsule as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Co-SDR Capsule . However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Co-SDR Capsule for longer than seven days. The most common side effect of Co-SDR Capsule is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume Co-SDR Capsule if you are hypersensitive to any components present in Co-SDR Capsule . Before taking the Co-SDR Capsule , inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Co-SDR Capsule may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or those taking doses higher than 30 mg daily. Co-SDR Capsule is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Co-SDR Capsule .

Uses of Co-SDR Capsule

Co-SDR Capsule is used in the treatment of nausea and vomiting. The detailed uses of Co-SDR Capsule are as follows: <br/> • Nausea Relief: Co-SDR Capsule is commonly used to relieve nausea and vomiting caused by various conditions, including motion sickness and post-operative effects.<br/> • Gastroesophageal Reflux Disease (GERD): Co-SDR Capsule helps in managing symptoms related to GERD by reducing stomach acid and promoting gastric emptying, which can alleviate discomfort.<br/> • Functional Dyspepsia: Co-SDR Capsule can aid in the treatment of functional dyspepsia, providing relief from bloating, early satiety, and stomach discomfort.<br/> • Gastroparesis: For patients with delayed gastric emptying (gastroparesis), Co-SDR Capsule can assist in stimulating gastric motility, thus improving symptoms related to indigestion and fullness.<br/>

Directions for Use

  • Co-SDR Capsule can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Co-SDR Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Co-SDR Capsule contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. Co-SDR Capsule also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

How Co-SDR Capsule Works

Co-SDR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Co-Sdr Cap
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Co-SDR Capsule

Do not take more than the prescribed dose of Co-SDR Capsule as it may cause overdose. The symptoms of overdose include uncontrolled movements which include unusual eye movements, sleepiness, confusion, abnormal posture (such as a twisted neck) or unusual movements of the tongue. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not consume Co-SDR Capsule if you are allergic to any components present in Co-SDR Capsule . Before taking the Co-SDR Capsule , contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Co-SDR Capsule may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Co-SDR Capsule , immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Co-SDR Capsule .

Drug-Drug Interactions

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DomperidoneToremifene
Severe
DomperidoneKetoconazole
Severe

Drug-Drug Interactions

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DomperidoneToremifene
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Co-Sdr Cap and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Co-Sdr Cap and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Ritonavir can increase the blood levels of Co-Sdr Cap.

How to manage the interaction:
There may be a possibility of interaction between Co-Sdr Cap and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Co-Sdr Cap and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Co-Sdr Cap and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Co-Sdr Cap:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Co-Sdr Cap and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Co-Sdr Cap and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Nefazodone can increase the blood levels of Co-Sdr Cap.

How to manage the interaction:
There may be a possibility of interaction between Co-Sdr Cap and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Co-Sdr Cap:
Combining Mizolastine with Co-Sdr Cap can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Co-Sdr Cap and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Co-Sdr Cap:
Coadministration of Co-Sdr Cap with Cisapride can increase the blood levels of Co-Sdr Cap.

How to manage the interaction:
There may be a possibility of interaction between Co-Sdr Cap and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
  • Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Co-SDR Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Drinking alcohol with Co-SDR Capsule may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Unsafe

Co-SDR Capsule is not usually recommended in pregnancy. However, inform your doctor if you are pregnant or planning for pregnancy before taking Co-SDR Capsule .

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Breast Feeding

Unsafe

Co-SDR Capsule is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe if prescribed

Co-SDR Capsule has no effect on your ability to drive or operate machinery.

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Liver

Caution

Co-SDR Capsule should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them.

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Kidney

Caution

Co-SDR Capsule should be taken with caution in patients with kidney problems. Your doctor will adjust your dose depending upon the condition of your disease.

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Children

Unsafe

Co-SDR Capsule should not be given to adolescents younger than 12 years of age or are less than 35 kg in weight.

Have a query?

FAQs

Co-SDR Capsule is used to treat nausea (feeling sick) and vomiting (being sick). Besides this, it also helps in the treatment of indigestion.

Co-SDR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract&amp;#039;s motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Co-SDR Capsule as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Yes, Co-SDR Capsule can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Co-SDR Capsule may cause side effects such as dry mouth, headache or diarrhoea. If these side effects persist or worsen, please consult your doctor.

If you are have any liver or kidney problem, inform your doctor so that an alternative medicine may be recommended.

You are recommended to avoid spicy and oily foods. Limit smoking and alcohol consumption as they may worsen the reflux (stomach acid rising into esophagus). Also, avoid carbonated drinks such as cold drinks and soda as the carbon dioxide gas in them may worsen acid reflux. Limit your intake of chocolate and mint. Some pain killers such as Ibuprofen may increase acidity and worsen the condition. Thus, avoid using these for prolonged duration.

Take Co-SDR Capsule only for the duration as prescribed by your doctor. If you get relief from your symptoms, consult your doctor for a follow-up, where your doctor may lower the dose. Long term use of Co-SDR Capsule may cause fractures, low vitamin B12 levels and magnesium levels. You need to be cautious about these and continue to monitor your blood levels regularly and if required your doctor may prescribe the supplements for these deficiencies.

Co-SDR Capsule is contraindicated in patients with a known hypersensitivity to domperidone or any other inactive ingredients of Co-SDR Capsule . Patients with underlying liver or kidney disease, should use caution.

Yes, the use of Co-SDR Capsule can cause diarrhoea. In case if you have diarrhoea, drink lots of water or other fluids. Avoid intake of fatty or fried foods along with Co-SDR Capsule . If diarrhoea persists and if you notice any signs of dehydration, such as decreased urination with dark colored and strong-smelling urine.

Store Co-SDR Capsule at room temperature in a cool and dry place. Protect from direct light and moisture. Keep it out of reach of children.

Yes, Co-SDR Capsule is safe if used as advised by the doctor. Follow your doctor’s instructions.

It is best to take Co-SDR Capsule before food. Take it the 15 to 30 minutes before a meal or snack or take it as advised by your doctor.

Take Co-SDR Capsule as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

You are recommended to take your doctor’s advice before taking Co-SDR Capsule if you are pregnant or breastfeeding.

Country of origin

India

Manufacturer/Marketer address

G1, 802, RS Nagar, Jaipur-302019, Rajasthan, India
Other Info - COS0158

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 22, 2025 | 1:27 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.nhs.uk/medicines/domperidone/
  2. https://www.medicines.org.uk/emc/files/pil.556.pdf

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