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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Clora 25 mg Tablet is used to treat obsessive-compulsive disorder (OCD), depression, panic and anxiety disorder. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). It contains Clomipramine, which works by increasing the activity of serotonin and noradrenaline (chemical messengers) in the brain involved in regulating mood, behaviour and emotions. Thereby, relieves depression, lighten the mood and relieve anxiety symptoms such as fear and panic. It may cause side effects such as dizziness, headache, drowsiness, dry mouth, nausea, weight gain, increased sweating, constipation, shaking, blurred vision, erectile dysfunction or difficulty in urination.Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CLOMIPRAMINE-25MG

Manufacturer/Marketer :

Sigmund Promedica

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clora 25 mg Tablet

Clora 25 mg Tablet belongs to a class of drugs called 'antidepressants' used to treat obsessive-compulsive disorder (OCD), depression, panic and anxiety disorder. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Depression is a mood disorder associated with symptoms such as sadness and the inability to sleep properly or enjoy life as you used to do. Panic or anxiety disorder is linked to anxiety with sudden feelings of unnecessary fear or worries even when there is no danger in reality.

Clora 25 mg Tablet contains Clomipramine, which works by increasing the activity of serotonin and noradrenaline (chemical messengers) in the brain, which is involved in regulating mood, behaviour, and emotions. Thereby, Clora 25 mg Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take Clora 25 mg Tablet with food as prescribed by your doctor and swallow whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you how often you take Clora 25 mg Tablet based on your medical condition. Some people may experience dizziness, headache, drowsiness, dry mouth, nausea, weight gain, increased sweating, constipation, shaking, blurred vision, erectile dysfunction or difficulty in urination. Most of these side effects of Clora 25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Clora 25 mg Tablet or any other medicines, please tell your doctor. Clora 25 mg Tablet is not recommended for children below 17 years of age. Avoid taking Clora 25 mg Tablet if you are pregnant, as it may cause harm to the foetus. Avoid breastfeeding while taking Clora 25 mg Tablet as it may be excreted in human milk and cause adverse effects in the baby. If you have any self-harming or suicidal thoughts before taking Clora 25 mg Tablet , inform your doctor as they may worsen in the initial days of taking Clora 25 mg Tablet .

Uses of Clora 25 mg Tablet

Treatment of Obsessive-compulsive disorder (OCD), Depression, Panic disorder, Anxiety disorder.

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Directions for Use

• Take Clora 25 mg Tablet with food to reduce gastrointestinal side effects or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Clora 25 mg Tablet contains Clomipramine, an antidepressant used to treat obsessive-compulsive disorder (OCD), depression, and panic disorder. Clora 25 mg Tablet increases the activity of serotonin and noradrenaline (chemical messengers) in the brain, which is involved in regulating mood, behaviour, and emotions. Thereby, Clora 25 mg Tablet helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic. Clora 25 mg Tablet , in combination with other medicines, may be used to treat cataplexy (a disorder that causes muscle weakness), which usually affects people suffering from narcolepsy (uncontrollable sleepiness during daytime).

How Clora 25 mg Tablet Works

Clora 25 mg Tablet contains Clomipramine, which works by increasing the activity of serotonin and noradrenaline (chemical messengers) in the brain, which is involved in regulating mood, behaviour, and emotions. Thereby, Clora 25 mg Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Storage

Keep Clora 25 mg Tablet out of the sight and reach of children.
Side effects of Clora 25 mg Tablet
  • Schedule a comprehensive medical evaluation with a specialized women's health expert.
  • Adhere to a personalized medication regimen to alleviate symptoms and promote ovarian health.
  • Embrace a holistic approach to wellness, incorporating nutritious eating habits and consistent physical activity.
  • Refrain from engaging in physically demanding tasks that may exacerbate discomfort.
  • Prioritize rejuvenation and relaxation, ensuring adequate sleep and downtime.
  • Explore complementary therapies, like acupuncture or botanical supplements, under the guidance of a qualified medical professional.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Call and consult your doctor if you observe prolonged and unusual bleeding during menstruation cycle.
  • Drink more fluids and your doctor may prescribe a suitable medication to reduce the bleeding.
  • Ensure to use the right hygiene products to prevent leakage and discomfort.
  • Talk to your doctor to know the cause, severity and appropriate treatment options.
  • Try pain relievers like ibuprofen or naproxen to relieve mild pelvic pain.
  • Consider pelvic floor exercises as it helps to strengthen muscles in the pelvic region and relieve pain.
  • Try relaxation techniques like deep breathing, meditation or gentle stretching.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.

What if I have taken an overdose of Clora 25 mg Tablet

Do not take more than the prescribed dose of Clora 25 mg Tablet as it may cause overdose. The symptoms of overdose include irregular heartbeats, low blood pressure, fits, drowsiness, muscle stiffness, restlessness, sweating, shortness of breath, dilated pupil or a decrease or absence of urine production. Severe overdose may lead to coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Clora 25 mg Tablet or any other medicines, please tell your doctor. Clora 25 mg Tablet is not recommended for children below 17 years of age. Avoid taking Clora 25 mg Tablet if you are pregnant as it may cause harm to the fetus. Avoid breastfeeding while taking Clora 25 mg Tablet as Clora 25 mg Tablet may be excreted in human milk and cause adverse effects in the baby. Therefore, please consult a doctor if you are pregnant, planning for pregnancy, or breastfeeding. Clora 25 mg Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Clora 25 mg Tablet , inform your doctor as they may worsen in the initial days of taking Clora 25 mg Tablet . Do not take Clora 25 mg Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide, tranylcypromine and phenelzine used to treat depression as it may cause severe adverse effects. Also, avoid taking Clora 25 mg Tablet with buprenorphine as it may cause a serious life-threatening condition. If you have fits, low blood pressure, mania, glaucoma, difficulty in urination, a blood disorder, hyperthyroidism (overactive thyroid gland), severe constipation, pheochromocytoma (tumor of the adrenal gland), low potassium levels in blood, kidney, liver, or heart problems, inform your doctor before taking Clora 25 mg Tablet .

Drug-Drug Interactions

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clomipheneOspemifene
Critical
clomipheneBexarotene
Severe

Drug-Drug Interactions

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clomipheneOspemifene
Critical
How does the drug interact with Clora 25 mg Tablet:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.

How to manage the interaction:
Taking Clora 25 mg Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneBexarotene
Severe
How does the drug interact with Clora 25 mg Tablet:
Co-administration of Clora 25 mg Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.

How to manage the interaction:
Although there is an interaction, Clora 25 mg Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Clora 25 mg Tablet:
Co-administration of Fluoroestradiol F 18 together with Clora 25 mg Tablet may reduce the action of Fluoroestradiol F 18.

How to manage the interaction:
Taking Clora 25 mg Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, and whole grains. Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen anxiety. Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Regularly attend therapy sessions.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT
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Alcohol

Unsafe

Avoid consumption of alcohol with Clora 25 mg Tablet as it may increase the risk of adverse effects such as drowsiness, blurred vision, or confusion.

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Pregnancy

Unsafe

Clora 25 mg Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Clora 25 mg Tablet as Clora 25 mg Tablet may be excreted in human milk and cause adverse effects in the baby. Therefore, please consult a doctor if you are a breastfeeding mother.

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Driving

Unsafe

Clora 25 mg Tablet may cause dizziness, tiredness, confusion, difficulty in concentrating or blurred vision. Therefore, avoid driving if you experience any of these symptoms after taking Clora 25 mg Tablet .

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Liver

Caution

Take Clora 25 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

If you have any concerns regarding the use of Clora 25 mg Tablet in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Clora 25 mg Tablet is not recommended for children below 17 years of age, as the safety and effectiveness were not established. Please consult a doctor before using Clora 25 mg Tablet .

FAQs

Clora 25 mg Tablet is used to treat obsessive-compulsive disorder (OCD), depression, panic and anxiety disorder.

Clora 25 mg Tablet contains Clomipramine that works by increasing the activity of serotonin and noradrenaline (chemical messengers) in the brain that are involved in regulating mood, behavior, and emotions. Thereby, Clora 25 mg Tablet helps in relieving depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Yes, Clora 25 mg Tablet may be used to treat panic disorder by reducing fear. However, please consult a doctor before using Clora 25 mg Tablet .

You are not recommended to take Clora 25 mg Tablet with buprenorphine as co-administration of these medicines may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, fits, diarrhea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Clora 25 mg Tablet with other medicines.

Yes, Clora 25 mg Tablet may cause self-harming or suicidal thoughts especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Clora 25 mg Tablet .

Clora 25 mg Tablet may cause impotence (inability to maintain an erection) in males and may decrease sexual desire (libido) in both men and women. However, if you experience any such problems while taking Clora 25 mg Tablet , please consult a doctor immediately.

It takes about 2 weeks or longer usually for Clora 25 mg Tablet to work. However, it is recommended to use Clora 25 mg Tablet for as long as your doctor has prescribed it for you.

Yes, Clora 25 mg Tablet may cause weight gain due to an increase in the appetite. Regular exercise and a healthy diet are recommended while taking Clora 25 mg Tablet to maintain proper body weight. However, if you notice any major changes in weight, please consult a doctor.

Yes, Clora 25 mg Tablet is safe if used as prescribed by your doctor. Do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects persist or worsen.

Clora 25 mg Tablet may cause side effects such as drowsiness, dizziness, constipation, erectile dysfunction, difficulty in urination, and dry mouth. If these side effects persist or worsen, please consult your doctor.

If you take an overdose of Clora 25 mg Tablet , you may experience symptoms such as irregular heartbeats, low blood pressure, fits, drowsiness, muscle stiffness, restlessness, sweating, shortness of breath, dilated pupil or a decrease or absence of urine production. Severe overdose may lead to coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

No, do not stop taking Clora 25 mg Tablet without consulting your doctor as discontinuing suddenly may worsen your condition and also cause withdrawal symptoms such as vomiting, nausea, dizziness, headache, weakness, fever, sleep problems, and irritability. Therefore, take Clora 25 mg Tablet for duration advised by your doctor for best results. If you any of these side effects are bothering you, contact your doctor.

Country of origin

India

Manufacturer/Marketer address

30-22-118, First Floor, Eluru Road,Seetharampuram,Vijayawada 520 002,Andhra Pradesh
Other Info - CLO0182

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