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compositionComposition:CLONIDINE-150MCG
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Prescription Medicine
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Cloneon Injection 1 ml is an antihypertensive medicine which is used in the treatment of high blood pressure. The mechanism of action of this medication is to relax and widen blood arteries, which facilitates the heart's ability to pump blood to every part of the body. This medicine may cause common side effects like dry mouth, headache, dizziness, nausea, and hypotension.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLONIDINE-150MCG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cloneon Injection 1 ml

Cloneon Injection 1 ml injection is a parenteral medication primarily used to treat severe pain in cancer patients that is not fully relieved by strong pain-relieving medicines alone. This prescription medication helps control severe, ongoing pain by blocking pain signals in the spinal cord. It is typically given in a hospital or clinic setting under close medical supervision.

Because this medicine is injected by a healthcare provider, it is given at consistent times to maintain steady levels in your body. It is injected directly, so you do not need to worry about taking it with or without food. To help get the best results, your doctor may suggest lifestyle changes such as gentle physical therapy, relaxation techniques, and eating a balanced diet to support your overall strength.

Some of the most common side effects of this treatment include a dry mouth, feeling very sleepy, and a drop in blood pressure. While these are usually manageable, you must consult your doctor immediately if you experience serious side effects like a dangerously slow heart rate, severe breathing difficulties, or profound confusion.

Talk to your doctor before starting this medicine if you have certain health conditions like a history of heart disease, blood pressure problems, or kidney damage. Do not take this if you have a severe infection at the injection site or if you have a bleeding disorder that makes spinal injections unsafe.

This medicine can interact with alcohol, sleeping pills, and other blood pressure lowering treatments, which can cause severe drowsiness or dangerously low blood pressure. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist to discuss the risks and benefits of using this medicine.

Uses of Cloneon Injection 1 ml

Cloneon Injection 1 ml may be used to help manage the following conditions:

  • Severe Cancer Pain: Cloneon Injection 1 ml helps by targeting the spinal cord pathways to block intense pain signals in cancer patients who do not get enough relief from standard opioid pain medicines alone.
  • Chronic Pain Management: In specific cases, this injection is used as an additional treatment to help manage other forms of severe, long-term pain that have not responded to typical treatments.

Key Benefits

Cloneon Injection 1 ml provides significant, targeted relief for patients dealing with severe, persistent pain. By working directly in the spinal cord, it offers several important benefits:

  • Targeted pain relief: It focuses directly on the nerves that transmit pain, helping to quiet intense pain signals before they reach the brain.
  • Improved pain control: When combined with other pain medicines like opioids, it makes them work better, allowing you to achieve comfort at lower opioid doses.
  • Better quality of life: By safely reducing severe pain, it helps you rest more comfortably, move with less discomfort, and focus on your daily recovery.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Cloneon Injection 1 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Cloneon Injection 1 ml Works

Cloneon Injection 1 ml contains clonidine. It works by stimulating specific receptors in the brain and spinal cord called alpha-2 receptors. When it is injected near the spine, it prevents the nerve cells from releasing chemicals that transmit pain signals to your brain. This action helps to calm overactive nerve pathways, effectively dampening the sensation of severe pain. In addition to blocking pain, Cloneon Injection 1 ml can also cause blood vessels to relax. While this relaxation can help lower blood pressure, its primary goal in parenteral use is to work alongside other pain medicines to provide deep, localised relief from severe pain.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Cloneon Injection 1 ml to avoid unpleasant side-effects.

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Pregnancy

Consult your doctor

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe Cloneon Injection 1 ml only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while on treatment with Cloneon Injection 1 ml. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

Cloneon Injection 1 ml may cause dizziness and sleepiness. Drive and operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Cloneon Injection 1 ml is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Cloneon Injection 1 ml should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Cloneon Injection 1 ml.

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Geriatrics

Caution

Cloneon Injection 1 ml should be used with caution and may require dose adjustment in elderly patients. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Cloneon Injection 1 ml

Because this medication is administered by professionals, an overdose is rare. If you experience symptoms of an overdose, such as extreme sleepiness, a very slow heart rate, shallow breathing, or cold skin, seek immediate medical attention or call emergency services.

Diet & Lifestyle Advise

  • Change positions slowly: To prevent dizziness from a sudden drop in blood pressure, take your time when standing up from a sitting or lying position.
  • Stay hydrated: Drink plenty of water throughout the day to help relieve dry mouth and maintain stable blood pressure, unless your doctor tells you otherwise.
  • Avoid alcohol completely: Alcohol can make you extremely drowsy and can dangerously interact with this medication.
  • Do not drive or operate machinery: This medicine can make you very sleepy and slow your reflexes, so avoid these tasks during your treatment.
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How Soon It Starts Working

  • The time required for Cloneon Injection 1 ml to start to work: The time required for Cloneon Injection 1 ml to show its action is unknown.
  • The time for which the effects of Cloneon Injection 1 ml last: The duration of action for Cloneon Injection 1 ml is unknown.

What if you forget to take Cloneon Injection 1 ml

Since this medicine is given by a healthcare provider in a clinic or hospital, it is unlikely that you will miss a dose. However, if you miss an appointment or suspect your infusion has stopped, contact your healthcare provider immediately to get instructions. Do not try to make up for a missed dose by increasing the amount yourself.

Storage

•Store Cloneon Injection 1 ml injection vials at room temperature, specifically between 20°C and 25°C (68°F and 77°F).

Drug Warnings

  • Check the solution: Always inspect the liquid in the vial or infusion bag before use; do not use it if it is cloudy, discoloured, or contains particles.
  • Do not stop suddenly: Never stop using this medicine abruptly, as this can cause a rapid, dangerous rise in your blood pressure.
  • Monitor your pump: If you use a portable infusion pump at home, make sure you know how it works and how to contact your nurse if the alarm sounds.
  • Track your blood pressure: Check your blood pressure and heart rate regularly as advised by your doctor to ensure they stay in a safe range.
  • Keep a medical card: Carry a card or wear a medical alert bracelet stating that you are receiving an epidural infusion of Cloneon Injection 1 ml in case of an emergency.

Drug-Drug Interactions

verifiedApollotooltip
  • Opioids and sedatives: Combining these with Cloneon Injection 1 ml can lead to severe drowsiness, deep sedation, and dangerous breathing difficulties.
  • Blood pressure medications: Taking other medicines that lower blood pressure can cause your pressure to drop too low, resulting in severe dizziness.
  • Beta-blockers: Using these heart medications together with Cloneon Injection 1 ml can cause your heart rate to slow down to an unsafe level.
  • Tricyclic antidepressants: These medicines can reduce the effectiveness of Cloneon Injection 1 ml in controlling your pain.
ClonidineClomipramine
Severe
ClonidinePindolol
Severe

Drug-Drug Interactions

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ClonidineClomipramine
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Clomipramine may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although taking clomipramine and Cloneon Injection 1 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ClonidinePindolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Pindolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Pindolol, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor.
ClonidineTrimipramine
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Trimipramine may increase the risk and severity of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Trimipramine, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not discontinue the medication without consulting a doctor.
ClonidineEsmolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
The combination of esmolol and Cloneon Injection 1 ml may reduce your blood pressure and lower your heart rate.

How to manage the interaction:
Although there is a possible interaction between Esmolol and Cloneon Injection 1 ml, you can take these medicines together if prescribed by a doctor. However, if you may experience a sluggish heartbeat, headaches, dizziness, or the sensation of passing out, consult the doctor. Do not discontinue any medications without consulting the doctor.
ClonidineAtenolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Atenolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Atenolol, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not discontinue the medication without consulting a doctor.
ClonidineSodium oxybate
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml can enhance the sedative effects of Sodium oxybate on the central nervous system.

How to manage the interaction:
Co-administration of Cloneon Injection 1 ml with Sodium oxybate can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and be aware of any changes. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
ClonidineNadolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Nadolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Nadolol, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not discontinue the medication without consulting a doctor.
ClonidineProtriptyline
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Protriptyline may increase the risk and severity of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Protriptyline, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not discontinue the medication without consulting a doctor.
ClonidineDoxepin
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Doxepin may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Doxepin, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not stop using any medications without consulting your doctor.
ClonidineAmitriptyline
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Amitriptyline may increase the risk and severity of increased side effects.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Amitriptyline, you can take these medicines together if prescribed by a doctor. However, contact a doctor if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache, or heart palpitations. Do not stop any medication without doctor's advise.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol entirely, as it severely increases the drowsy and calming effects of this medicine, which can be dangerous.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Cloneon Injection 1 ml belongs to a class of medicines called antihypertensives used to treat hypertension (high blood pressure). Besides this, Cloneon Injection 1 ml is also used alone or in combination with opiate medicines for the treatment of severe pain in cancer patients which is not sufficiently relieved by opioid analgesics alone.
Cloneon Injection 1 ml relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke. Cloneon Injection 1 ml prevents the transmission of pain signals to the brain, thereby provides relief from pain.
Dry mouth could be a side effect of Cloneon Injection 1 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Postural hypotension could be a side-effect of Cloneon Injection 1 ml. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.
Please consult your doctor before taking other medicines with Cloneon Injection 1 ml. Particularly, inform your doctor if you are taking medicines used to treat high blood pressure, heart problems, depression, mood swings, or pain relievers.
Cloneon Injection 1 ml injection is primarily used to manage severe cancer pain that is not completely relieved by standard opioid pain medications alone. It is typically given in combination with other pain relievers. Talk to your doctor to see if this treatment is suitable for you.
This parenteral medicine is given as an injection or a continuous infusion into the epidural space around your spinal cord. Because it requires specialised placement, it is always given by a trained healthcare professional in a clinic or hospital setting. Talk to your doctor if you have questions about how it will be administered.
No, you must never stop this medicine suddenly. Doing so can cause a rapid, dangerous rise in blood pressure, along with symptoms like nervousness, headache, and shaking. Your healthcare provider will help you slowly reduce your dose if you need to stop. Talk to your doctor before making any changes.
Yes, drowsiness, sleepiness, and tired feelings are very common when receiving this medicine. You should avoid activities that require you to be alert, such as driving or operating machinery, while on this medication. Talk to your doctor if you find the sleepiness difficult to manage.
Dizziness is often caused by a temporary drop in blood pressure. Try to sit or lie down immediately, and stand up very slowly when you feel better. Talk to your doctor or pharmacist if the dizziness continues or is accompanied by fainting.
No, you should avoid alcohol completely while using this medicine. Alcohol can increase the sedative effects of the medication, making you extremely drowsy and slowing your breathing to a dangerous level. Talk to your doctor if you need support with avoiding alcohol.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides it is absolutely necessary. It can affect the baby's heart rate and blood pressure. Talk to your doctor to discuss safer pain management options during this time.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - CLO0138
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