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compositionComposition:CLOFAZIMINE-100MG
prescription
Prescription Medicine
info
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Clofros 100 Capsule is used to treat leprosy (infectious disease-causing skin lesions and nerve damage). It contains Clofazimine, which works by inhibiting the growth of disease-causing organisms (Mycobacterium leprae) in the body. In some cases, this medicine may cause side effects such as stomach and epigastric pain, diarrhoea, nausea, and vomiting.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLOFAZIMINE-100MG

Manufacturer/Marketer :

Sangrose Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Clofros 100 Capsule

Clofros 100 Capsule is used to treat Leprosy (infectious disease-causing skin lesions and nerve damage). Leprosy, commonly known as Hansen's disease, is caused by Mycobacterium leprae, which is a chronic infectious disease. The illness mostly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory system, and the eyes. Leprosy can affect anyone at any age, from infancy to old age.

Clofazimine is the active component in Clofros 100 Capsule. It works by inhibiting the growth of disease-causing organisms (Mycobacterium) in the body. Thus, Clofros 100 Capsule aids in the treatment of Leprosy.

Take Clofros 100 Capsule daily at the same time to ensure better efficacy. The dose and duration of Clofros 100 Capsule can vary depending on your condition and the severity of the infection. In some situations, you may experience symptoms such as stomach and epigastric pain, diarrhoea, nausea, and vomiting. These negative impacts do not necessitate medical treatment and will gradually subside. However, if you are experiencing these undesirable effects frequently, you should consult your doctor.

Continue using Clofros 100 Capsule for as long as your doctor has prescribed it to treat your illness effectively. Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with Clofros 100 Capsule. Clofros 100 Capsule may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking Clofros 100 Capsule. If pregnant or breastfeeding, consult your doctor before using Clofros 100 Capsule. Do not use Clofros 100 Capsule in more than specified doses or for an extended time. Before taking Clofros 100 Capsule, inform your doctor about your medical history and any other medications you currently use to rule out possible side effects.

Uses of Clofros 100 Capsule

Clofros 100 Capsule is used in the treatment of Leprosy. The detailed use of Clofros 100 Capsule is as follows:

  • Lepromatous Leprosy: Clofros 100 Capsule is especially effective in cases resistant to dapsone or complicated by erythema nodosum leprosum.

Key Benefits

Clofros 100 Capsule contains Clofazimine, an antileprotic drug used in treating Leprosy in conjunction with other medications. It works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy. The doctor may prescribe Clofros 100 Capsule to treat various bacterial infections due to Mycobacterium.

Side effects of Clofros 100 Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid triggering foods like spicy and fatty foods.
  • Eat smaller meals and digestible foods.
  • Regular exercise can improve gastrointestinal health.
  • Avoid sleeping immediately after eating as it can worsen digestion and lead to discomfort.
  • Drink plenty of water to stay hydrated.
  • Manage stress through relaxation techniques.

Directions for Use

  • Clofros 100 Capsule should be taken with food or milk to enhance its absorption and reduce gastrointestinal side effects.
  • It is recommended to take Clofros 100 Capsule once daily or as advised by your doctor.
  • Chew the tablet completely before swallowing.
  • Do not swallow it as a whole.

How Clofros 100 Capsule Works

Clofazimine is the active component in Clofros 100 Capsule. It works by inhibiting the growth of disease-causing organisms (Mycobacterium) in the body. Thus, Clofros 100 Capsule aids in the treatment of Leprosy.
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Alcohol

Caution

It is not known whether Clofros 100 Capsule interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Consult your doctor; there has been no significant research on the use of Clofros 100 Capsule in pregnant women.

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Breast Feeding

Caution

Consult your doctor; there has been no significant research on the use of Clofros 100 Capsule in breastfeeding/nursing moms.

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Driving

Caution

Clofros 100 Capsule can occasionally cause dizziness/drowsiness. Therefore, drive only if you are alert after taking Clofros 100 Capsule.

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Liver

Caution

Rarely, Clofros 100 Capsule may cause liver damage. Caution should be exercised while using Clofros 100 Capsule in patients with severe liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using Clofros 100 Capsule in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Clofros 100 Capsule should be used with caution in children, only when prescribed by a child specialist.

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Heart

Unsafe

Clofros 100 Capsule should not be taken if you have pre-existing heart disease. Consult your doctor before use if you have any medical conditions or concerns.

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Geriatrics

Caution

Limited information is available regarding the usage of Clofros 100 Capsule in elders, so please consult a doctor if you have any concerns.

What if I have taken an overdose of Clofros 100 Capsule

Take Clofros 100 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach and blueberries.

  • Consuming food rich in probiotics helps develop the immune system against allergies.

  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs and nuts.

  • Avoid consuming foods with excess sugar, as it may flare up inflammation.

  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.

  • Reducing stress and maintaining a good sleep cycle would be helpful.

  • Avoid getting in contact with harsh soaps, detergents and rough fabrics.

health query

Have a query?

How Soon It Starts Working

The time required for Clofros 100 Capsule to start to work: The exact onset time of Clofros 100 Capsule has not been clinically established. The time for which the effects of Clofros 100 Capsule last: The duration of Clofros 100 Capsule’s effect is clinically not established.

What if you forget to take Clofros 100 Capsule

If you forget to take a dose of Clofros 100 Capsule, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Clofros 100 Capsule out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with Clofros 100 Capsule. Clofros 100 Capsule may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking Clofros 100 Capsule. If pregnant or breastfeeding, consult your doctor before using Clofros 100 Capsule. Do not use Clofros 100 Capsule in more than specified doses or for an extended time. Before taking Clofros 100 Capsule, inform your doctor about your medical history and any other medications you currently use to rule out possible side effects. Sun lamps should be avoided. Clofazimine may increase your skin's sensitivity to sunlight or sunlamps. Therefore, wear protective clothing when exposed to direct sunlight and apply sunscreen with an SPF of at least 15.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Clofros 100 Capsule may interact with antibiotics (e.g. azithromycin, trimethoprim, sulfamethoxazole, and trimethoprim) and antacids (e.g. aluminium hydroxide, magnesium hydroxide, and simethicone).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Brief your doctor if you have a medical history of allergic reactions to medicines, GI effects, or renal dysfunction before taking Clofros 100 Capsule.

ClofazimineMesoridazine
Critical
ClofazimineThioridazine
Critical

Drug-Drug Interactions

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ClofazimineMesoridazine
Critical
How does the drug interact with Clofros 100 Capsule:
When Clofros 100 Capsule is taken with Mesoridazine, it can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Using Clofros 100 Capsule with Mesoridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineThioridazine
Critical
How does the drug interact with Clofros 100 Capsule:
When Clofros 100 Capsule is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Clofros 100 Capsule with Thioridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineZiprasidone
Critical
How does the drug interact with Clofros 100 Capsule:
Taking Clofros 100 Capsule with Ziprasidone can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Clofros 100 Capsule with Ziprasidone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDofetilide
Critical
How does the drug interact with Clofros 100 Capsule:
When Clofros 100 Capsule is taken with Dofetilide, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Clofros 100 Capsule with Dofetilide is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineCisapride
Critical
How does the drug interact with Clofros 100 Capsule:
When Clofros 100 Capsule is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Clofros 100 Capsule with Cisapride is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDronedarone
Critical
How does the drug interact with Clofros 100 Capsule:
When Clofros 100 Capsule is taken with Dronedarone, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Clofros 100 Capsule with Dronedarone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineArsenic trioxide
Severe
How does the drug interact with Clofros 100 Capsule:
Co-administration of arsenic trioxide with Clofros 100 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking arsenic trioxide with Clofros 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineVemurafenib
Severe
How does the drug interact with Clofros 100 Capsule:
Co-administration of vemurafenib with Clofros 100 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking vemurafenib with Clofros 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineDolasetron
Severe
How does the drug interact with Clofros 100 Capsule:
Co-administration of dolasetron with Clofros 100 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking dolasetron with Clofros 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineDisopyramide
Severe
How does the drug interact with Clofros 100 Capsule:
Co-administration of disopyramide with Clofros 100 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking disopyramide with Clofros 100 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTILEPROTICS]

FAQs

Clofros 100 Capsule is used to treat Leprosy (infectious disease-causing skin lesions and nerve damage).
Clofros 100 Capsule works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy.
To treat your illness effectively, continue taking Clofros 100 Capsule for as long as your doctor has prescribed it. Talk to the doctor if you have any concerns.
The common side effects of Clofros 100 Capsule include stomach and epigastric pain, diarrhoea, nausea, and vomiting. If you are experiencing these side effects frequently, please consult your doctor.
Clofros 100 Capsule may cause skin discoloration within a few weeks of use, ranging from orange-pink to brownish-black. This discoloration is generally reversible after stopping the medication, but it may take several months or even years for the skin to return to its normal appearance. If the skin discoloration significantly affects your mood or causes distress, please consult your doctor immediately.
Clofros 100 Capsule should not be used by individuals who are allergic to any of its ingredients. It should also be avoided by patients with severe liver or kidney dysfunction, as it may worsen these conditions.
Clofros 100 Capsule is generally safe when used at the dose and for the duration prescribed by your doctor. However, if you experience any unusual symptoms after taking Clofros 100 Capsule, please report them to your doctor.
If you forget to take a dose of Clofros 100 Capsule, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 19500Slr010 Lamprene Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. ScienceDirect Topics. Clofazimine - Research & Medical Applications Summary. Amsterdam, Netherlands: Elsevier; 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Center for Biotechnology Information (NCBI). Nbk501304 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Clofazimine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. ScienceDirect ScienceDirect. [Accessed on 01 Apr. 2019]Check here
  6. Clofazimine [Prescribing Information]. 2019. [Accessed on 25 Jul. 2024]Check here
  7. Clofazimine [Prescribing Information]. [Accessed on 04 Nov. 2025]Check here

Country of origin

India
Other Info - CL30475
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