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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cloff Dry Syrup is used to treat a wide range of bacterial infections. It contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. Thus, it helps prevent infections. Common side effects of Cloff Dry Syrup are feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping.

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Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Cloff Dry Syrup

Cloff Dry Syrup belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Cloff Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Dry Syrup helps in the prevention of infections.

Like all medicines, Cloff Dry Syrup may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Cloff Dry Syrup unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Cloff Dry Syrup

Cloff Dry Syrup is used in the treatment of Bacterial infections. The detailed uses of Cloff Dry Syrup are as follows:<br/>• Respiratory Tract Infections: Cloff Dry Syrup is prescribed to treat infections like bronchitis and community-acquired pneumonia. It works by stopping the growth of bacteria in the lungs and airways, helping relieve symptoms such as cough, fever, and breathing difficulty.<br/>• Ear, Nose, and Throat Infections: Cloff Dry Syrup is effective in managing conditions like otitis media (middle ear infection), sinusitis, pharyngitis, and tonsillitis. It helps reduce inflammation, ear pain, sore throat, and fever by eliminating the causative bacteria.<br/>• Skin and Soft Tissue Infections: Cloff Dry Syrup treats mild to moderate skin infections such as cellulitis, impetigo, and infected wounds. It works by targeting the bacteria responsible, reducing redness, swelling, and promoting healing.<br/>• Dental and Oral Infections: Cloff Dry Syrup may be used to treat bacterial infections in the teeth and gums, such as dental abscesses, by controlling bacterial growth and reducing pain and swelling.<br/>• Infections in Immunocompromised Children: Cloff Dry Syrup can be used to treat or prevent infections like Mycobacterium avium complex (MAC) in children with weakened immune systems, such as those with HIV.<br/>

Directions for Use

• Cloff Dry Syrup can be administered with or without food as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.• Shake well before use.

Medicinal Benefits

Cloff Dry Syrup belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

How Cloff Dry Syrup Works

Cloff Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Dry Syrup helps in the prevention of infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cloff Dry Syrup out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cloff Dry Syrup 30 ml
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Cloff Dry Syrup

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Cloff Dry Syrup may include severe stomach pain, nausea, vomiting, and diarrhea. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before using Cloff Dry Syrup, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Cloff Dry Syrup unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Cloff Dry Syrup in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Cloff Dry Syrup and iron supplements and antacids.

Drug-Drug Interactions

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ClarithromycinLomitapide
Critical

Drug-Drug Interactions

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ClarithromycinLomitapide
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Lomitapide is taken with Cloff Dry Syrup 30 ml, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Dry Syrup 30 ml:
Co-administration of Cloff Dry Syrup 30 ml and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinConivaptan
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Cloff Dry Syrup 30 ml is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinFlibanserin
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
When Flibanserin is taken with Cloff Dry Syrup 30 ml, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Dry Syrup 30 ml:
When Alfuzosin and Cloff Dry Syrup 30 ml can increase the risk or severity of side effects like low blood pressure or irregular heart rates.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with alfuzosin is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, or chest discomfort, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
Co-administration of Bepridil with Cloff Dry Syrup 30 ml may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloff Dry Syrup 30 ml:
Taking Cloff Dry Syrup 30 ml with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Dry Syrup 30 ml:
Taking Cloff Dry Syrup 30 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Cloff Dry Syrup 30 ml and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinDroperidol
Critical
How does the drug interact with Cloff Dry Syrup 30 ml:
Co-administration of Droperidol with Cloff Dry Syrup 30 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloff Dry Syrup 30 ml:
Co-administration of Cloff Dry Syrup 30 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Cloff Dry Syrup 30 ml and Simvastatin together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Cloff Dry Syrup to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Cloff Dry Syrup.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Cloff Dry Syrup can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

Have a query?

FAQs

Cloff Dry Syrup is used to treat Bacterial infections.

Cloff Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Dry Syrup helps in the prevention of infections.

After taking antibiotics such as Cloff Dry Syrup, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Cloff Dry Syrup treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.

No, Cloff Dry Syrup is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor&#039;s advice only.

Side effects are rare with Cloff Dry Syrup and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA.
Other Info - CLO1038

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