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About Cleft 20 Tablet
Cleft 20 Tablet is used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales).
Cleft 20 Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling.
Take Cleft 20 Tablet at the same time every day as prescribed by your doctor. In some cases, Cleft 20 Tablet may cause common side effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Cleft 20 Tablet if you are pregnant or planning for pregnancy, as Cleft 20 Tablet may cause serious congenital disabilities. Cleft 20 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Cleft 20 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol along with Cleft 20 Tablet as it could lead to increased dizziness and liver damage. Cleft 20 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Uses of Cleft 20 Tablet
Directions for Use
Medicinal Benefits
Cleft 20 Tablet belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Cleft 20 Tablet is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.
How Cleft 20 Tablet Works
Storage
What if I have taken an overdose of Cleft 20 Tablet
Drug Warnings
Do not take Cleft 20 Tablet if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Cleft 20 Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Cleft 20 Tablet if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Cleft 20 Tablet may cause dizziness, so drive with caution. Cleft 20 Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
Performing yoga may also help in improving joint flexibility and pain management.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Acupuncture, massage and physical therapy may also be helpful.
Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
Avoid smoking and alcohol consumption.
Habit Forming
Therapeutic Class
Product Substitutes
Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Cleft 20 Tablet . Alcohol intake, along with Cleft 20 Tablet , may cause liver disease.
Pregnancy
Unsafe
It is not recommended to take Cleft 20 Tablet while you are pregnant. Cleft 20 Tablet may cause serious birth defects.
Breast Feeding
Unsafe
It is not recommended to take Cleft 20 Tablet while you are breastfeeding. Cleft 20 Tablet passes into breast milk.
Driving
Caution
Cleft 20 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.
Liver
Caution
Please consult your doctor if you have liver impairment before taking Cleft 20 Tablet .
Kidney
Caution
Please consult your doctor if you have kidney impairment before taking Cleft 20 Tablet .
Children
Unsafe
Cleft 20 Tablet is not approved for children under the age of 18 years.
Have a query?
Cleft 20 Tablet is used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis.
Cleft 20 Tablet is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).
Cleft 20 Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Cleft 20 Tablet . Take Cleft 20 Tablet for as long as your doctor has prescribed to treat your condition effectually.
Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).
The best time to take leflunomide is usually in the morning, with food, to help minimize stomach upset. However, following your doctor's specific instructions for taking leflunomide is essential, as the optimal timing may vary depending on your needs and health status.
Cleft 20 Tablet is not a steroid. It contains leflunomide, which is an immunomodulatory medication used to treat rheumatoid arthritis and psoriatic arthritis. Leflunomide works by reducing inflammation and slowing the progression of the disease.
Cleft 20 Tablet may cause weight loss as a side effect. This weight loss is usually insignificant and may be due to a loss of appetite. If you experience significant weight loss, it is essential to consult your doctor.
Patients taking leflunomide should notify their doctor if they experience any unusual symptoms, side effects, or concerns. They should also keep their doctor informed about any changes in their health or medications.
Cleft 20 Tablet takes a long time to be eliminated from your body. It is generally recommended to wait at least 2 years after stopping Cleft 20 Tablet before planning a pregnancy. It is essential to consult your healthcare provider for personalized advice and to discuss the best plan for pregnancy after stopping Cleft 20 Tablet .
While taking leflunomide, it's reassuring to know that the risk of cancer is extremely low. Although there's a slight increase in the risk of certain types of cancer, such as lymphoma, this is very rare. Your healthcare provider will closely monitor you and address any concerns. Regular check-ups make you feel confident and safe while managing your condition with leflunomide.
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