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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Celdach 100 Inj is used to treat Colon and rectal cancer. It contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer. Sometimes, Celdach 100 Inj may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

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Whats That

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Composition :

OXALIPLATIN-100MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Celdach 100 Inj

Celdach 100 Inj belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer).

Celdach 100 Inj contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.

In some cases, Celdach 100 Inj may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Celdach 100 Inj if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Celdach 100 Inj. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Celdach 100 Inj

Celdach 100 Inj is used in the treatment of Colon and rectal cancer. The detailed uses of Celdach 100 Inj are as follows:<br/>• Stage III colon cancer: Celdach 100 Inj is used to treat colon cancer after surgical removal of the tumor, to reduce the risk of recurrence.<br/>• Advanced or metastatic colorectal cancer: Celdach 100 Inj is used to treat metastatic colorectal cancer as part of first-line or second-line therapy.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Celdach 100 Inj will be administered by a nurse or doctor.• Do not self-administer.

Medicinal Benefits

Celdach 100 Inj contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Celdach 100 Inj works by killing the cancer cells. Thereby, it helps treat cancer. Celdach 100 Inj may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

How Celdach 100 Inj Works

Celdach 100 Inj contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep Celdach 100 Inj out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Celdach 100 Inj
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.

What if I have taken an overdose of Celdach 100 Inj

As Celdach 100 Inj is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Celdach 100 Inj may cause chest pain, diarrhea, numbness or tingling in the fingers or toes, slowed breathing, slowed heartbeat, shortness of breath, tightening of the throat, vomiting, and wheezing.

Drug Warnings

Do not use Celdach 100 Inj if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Celdach 100 Inj:
Combining Celdach 100 Inj with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Celdach 100 Inj with Ziprasidone is not recommended, please consult your doctor before taking it.
How does the drug interact with Celdach 100 Inj:
Taking Tofacitinib with Celdach 100 Inj may increase the risk of infection.

How to manage the interaction:
Although taking Celdach 100 Inj and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
How does the drug interact with Celdach 100 Inj:
Co-administration of Celdach 100 Inj with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Although taking Celdach 100 Inj and Clozapine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Celdach 100 Inj:
The combined use of Celdach 100 Inj and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Celdach 100 Inj and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Celdach 100 Inj:
Using ivabradine together with Celdach 100 Inj can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Celdach 100 Inj and Ivabradine, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Celdach 100 Inj:
The combined use of Celdach 100 Inj and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of oxalipatin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Celdach 100 Inj:
Combining Cladribine with Celdach 100 Inj can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Celdach 100 Inj and Cladribine, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Celdach 100 Inj:
Using Moxifloxacin together with Celdach 100 Inj can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Celdach 100 Inj and Moxifloxacin, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat). Do not stop using any medications without a doctor's advice.
How does the drug interact with Celdach 100 Inj:
Taking Celdach 100 Inj with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Celdach 100 Inj and Ceritinib, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Celdach 100 Inj:
Using chloroquine together with Celdach 100 Inj can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Celdach 100 Inj together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY
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Alcohol

Consult your doctor

It is not known if alcohol affects Celdach 100 Inj. Please consult your doctor.

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Pregnancy

Unsafe

Celdach 100 Inj may cause foetal harm. Therefore, avoid becoming pregnant during treatment with Celdach 100 Inj.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Celdach 100 Inj and for three months after the last dose.

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Driving

Caution

Celdach 100 Inj may cause dizziness or vision problems. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Celdach 100 Inj.

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Kidney

Caution

Celdach 100 Inj should not be used if you have severe kidney disease. If you have mild or moderate kidney disease, inform your doctor before receiving Celdach 100 Inj.

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Children

Unsafe

Celdach 100 Inj is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Celdach 100 Inj is used to treat Colon and rectal cancer.

Celdach 100 Inj works by killing the cancer cells. Thereby, it helps treat cancer.

Celdach 100 Inj may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with Celdach 100 Inj.

Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of Celdach 100 Inj. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.

Celdach 100 Inj may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with Celdach 100 Inj.

Celdach 100 Inj is administered to you through an intravenous (IV) infusion. A healthcare professional usually gives it in a clinical setting.

The common side effects of Celdach 100 Inj are mild nausea, vomiting, diarrhoea, headache, peripheral neuropathy, fatigue, back pain, and stomach pain. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - CEL0207

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