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compositionComposition:CEFOTAXIME-1000MG
prescription
Prescription Medicine
info
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Ceftox 1 gm Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria and thereby helps reduce various bacterial infections like lung, skin, soft tissue, urinary tract, genital tract, heart valves, spine, brain, abdomen and blood infections. It helps by inhibiting the bacterial cell synthesis and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CEFOTAXIME-1000MG

Manufacturer/Marketer :

Laborate Pharmaceuticals India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Ceftox 1 gm Injection

Ceftox 1 gm Injection is an injectable antibiotic used to treat a wide variety of severe bacterial infections. It is prescribed for serious, deep-seated conditions such as infections of the brain (meningitis), lungs (pneumonia), abdomen, skin, and urinary tract.

Since this medicine is given as an injection, a healthcare provider will typically inject it at regular intervals throughout the day to keep a steady level in your body. It is vital to complete your full treatment course exactly as prescribed, regardless of food intake, to ensure the infection is completely cleared. Getting plenty of rest and staying well-hydrated are helpful lifestyle practices that support your body's recovery.

Common side effects of this medication include pain or swelling at the injection site, mild diarrhoea, and feeling sick to your stomach. You should contact your doctor immediately if you experience severe, watery diarrhoea, skin rashes, or sudden difficulty breathing.

Before you begin treatment, tell your doctor if you have kidney disease, stomach disorders like colitis, or a history of drug allergies. Do not take this if you have ever had a life-threatening allergic reaction to similar cephalosporin or penicillin antibiotics.

Some medications, such as strong water pills, can increase the risk of kidney damage when used alongside Ceftox 1 gm Injection. Speak with your healthcare provider if you are pregnant, breastfeeding, or managing health conditions as an older adult, as your dose may need to be carefully adjusted.

Uses of Ceftox 1 gm Injection

Ceftox 1 gm Injection helps treat serious bacterial infections by stopping the growth of harmful bacteria throughout the body. Your doctor may recommend it for the following conditions:

  • Brain infections (Meningitis): Ceftox 1 gm Injection helps by crossing into the brain and spinal fluids to eliminate the bacteria causing dangerous inflammation.
  • Lung infections (Pneumonia): Ceftox 1 gm Injection fights severe respiratory tract infections by stopping the growth of bacteria in the lungs.
  • Abdominal infections (Peritonitis): Ceftox 1 gm Injection helps treat peritonitis, an infection inside the abdomen, by targeting the bacteria causing the infection.
  • Urinary tract infections (UTIs): Ceftox 1 gm Injection clears complicated infections in the kidneys and bladder by eliminating the causative bacteria.
  • Skin and soft tissue infections: Ceftox 1 gm Injection stops the spread of bacteria in deep skin layers, muscles, and surgical wounds.
  • Bloodstream infections (Sepsis): Ceftox 1 gm Injection works rapidly throughout the body to clear bacteria from the blood, preventing life-threatening complications.

Key Benefits

Because Ceftox 1 gm Injection is injected directly into a vein or muscle, it enters your bloodstream immediately. This rapid delivery helps control severe, fast-spreading infections much quicker than oral antibiotics can. Key benefits of this treatment include:

  • Rapid symptom relief: Patients often notice a significant reduction in fever, pain, and inflammation within the first few days of treatment.
  • High effectiveness: It successfully treats complex bacterial strains that may be resistant to other common medicines.
  • Surgical protection: When used before certain surgeries, it helps prevent infections from developing at the surgical site.
Side effects of Ceftox 1 gm Injection
  • Drink plenty of water to stay hydrated.
  • Avoid foods that can cause black stools, such as liquorice, blueberries, and iron-rich foods.
  • Practice stress-reducing techniques like meditation, deep breathing, or yoga to help minimize stress-related digestive issues.
  • Avoid taking medications that can cause black stools, such as iron supplements or bismuth subsalicylate.
  • Monitor your stool colour, consistency, and frequency to identify any changes or patterns.
  • Seek medical attention if you experience persistent or severe black stools, abdominal pain, or other symptoms.
  • Get tested if your doctor suspects an underlying condition, such as gastrointestinal bleeding or ulcers.
  • Make lifestyle changes, such as getting regular exercise and quitting smoking, to help improve overall digestive health.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Ceftox 1 gm Injection will be administered by the doctor.
  • Do not self-administer.

How Ceftox 1 gm Injection Works

Ceftox 1 gm Injection contains cefotaxime; it is a third-generation cephalosporin antibiotic with activity against a wide range of bacteria, particularly many gram-negative bacteria, as well as some gram-positive bacteria. Doctors may choose it when a serious bacterial infection requires an injectable antibiotic with broad coverage, especially when the specific bacteria causing the infection are not yet known. Ceftox 1 gm Injection works by preventing bacteria from forming their protective cell walls. Without a strong cell wall, the bacteria become weak, rupture, and die. This action specifically targets bacterial cells without harming human cells, as human cells do not have cell walls. By eliminating the bacteria causing the infection, Ceftox 1 gm Injection helps your body's immune system clear the remaining infection and supports the healing process.
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Alcohol

Caution

It is unknown whether alcohol affects Ceftox 1 gm Injection. However, it is best to avoid or limit alcohol consumption as a precaution.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ceftox 1 gm Injection.

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Breast Feeding

Caution

Inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Ceftox 1 gm Injection.

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Driving

Caution

Ceftox 1 gm Injection may cause a reduction in mental awareness; thus, avoid using machinery or driving unless you are alert.

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Liver

Caution

Ceftox 1 gm Injection to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Ceftox 1 gm Injection to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Ceftox 1 gm Injection should be used in children only if recommended by a child specialist.

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Heart

Caution

Ceftox 1 gm Injection is generally safe for heart patients but should be given with caution. Rapid IV administration may affect heart rhythm, so medical supervision is essential.

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Geriatrics

Caution

Geriatric patients can receive Ceftox 1 gm Injection, but with careful monitoring. Older adults may have reduced kidney function, so dosage adjustments and supervision are important to avoid side effects.

What if I have taken an overdose of Ceftox 1 gm Injection

Because this medication is usually administered by a healthcare professional, an overdose is highly unlikely. However, if you suspect you have received too much or experience severe muscle twitching or seizures, seek immediate emergency medical care.

Diet & Lifestyle Advise

  • Support your gut: Consider eating probiotic-rich foods like yoghurt or taking a probiotic supplement a few hours after your injection to help restore healthy gut bacteria.
  • Drink plenty of water: Stay well-hydrated to help your kidneys process and safely clear the medication from your body.
  • Prioritise rest: Allow your body time to heal by avoiding strenuous activities and getting 7–9 hours of sleep each night.
  • Eat balanced meals: Focus on nutrient-dense foods, including lean proteins, fruits, and vegetables, to help rebuild your immune strength.
health query

Have a query?

How Soon It Starts Working

The time required for Ceftox 1 gm Injection to start to work: The time required for Ceftox 1 gm Injection to show its action is unknown. The time for which the effects of Ceftox 1 gm Injection last: The effect of Ceftox 1 gm Injection lasts for 24 hours.

What if you forget to take Ceftox 1 gm Injection

If you miss a dose of Ceftox 1 gm Injection, contact your healthcare provider immediately for instructions. Do not receive a double dose to make up for a missed one.

Storage

•Store the dry powder vials of Ceftox 1 gm Injection at 20°C to 25°C, protected from direct light and moisture.•Keep out of the reach of children and pets.

Drug Warnings

  • Inspect the liquid: Always check the mixed solution before injecting; do not use it if it is cloudy, discoloured, or contains visible particles.
  • Rotate injection sites: Change the exact spot where you inject each time to prevent pain, hard lumps, or tissue damage.
  • Never reuse needles: Use a sterile needle and syringe for every single injection, and discard them immediately in a sharps container.
  • Do not stop early: Complete the full course of treatment even if you feel completely recovered, as stopping early can cause the infection to return and resist future treatments.
  • Avoid self-treating diarrhoea: If you develop severe, watery diarrhoea, do not take over-the-counter anti-diarrhoeal medicines. Contact your doctor immediately.

Drug-Drug Interactions

verifiedApollotooltip
  • Aminoglycoside antibiotics: Combining these with Ceftox 1 gm Injection may increase the risk of kidney damage.
  • Strong diuretics (water pills like furosemide): May increase the likelihood of kidney problems.
  • Probenecid: Can slow down how quickly your kidneys remove Ceftox 1 gm Injection from your body, raising the levels of the medicine in your blood.
  • Typhoid vaccine: This antibiotic may decrease the effectiveness of live bacterial vaccines.

 

CeftriaxoneCalcium chloride
Critical
CeftriaxoneCalcium gluconate
Critical

Drug-Drug Interactions

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CeftriaxoneCalcium chloride
Critical
How does the drug interact with Ceftox 1 gm Injection:
Co-administration of Calcium chloride with Ceftox 1 gm Injection can increase the risk of side effects.

How to manage the interaction:
Taking Ceftox 1 gm Injection with Calcium chloride is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCalcium gluconate
Critical
How does the drug interact with Ceftox 1 gm Injection:
Co-administration of Calcium gluconate with Ceftox 1 gm Injection can increase the risk of adverse effects.

How to manage the interaction:
Taking Ceftox 1 gm Injection with Calcium gluconate is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCholera, live attenuated
Severe
How does the drug interact with Ceftox 1 gm Injection:
Taking the cholera vaccine after or along with Ceftox 1 gm Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Ceftox 1 gm Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. To ensure adequate vaccine response, you should not receive cholera vaccine, live until at least 14 days after you complete your antibiotic therapy. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

There are no known major interactions between Ceftox 1 gm Injection and specific foods, as this medication is injected and bypasses the digestive system.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Ceftox 1 gm Injection belongs to a class of drugs known as cephalosporin antibiotics used to treat various bacterial infections such as lung, skin, soft tissue, urinary tract, genital tract, heart valves, spine, brain, abdomen and blood infections. Apart from that, it may also be used to prevent infection before surgery, as well as during and after a caesarean section to prevent infections.
Ceftox 1 gm Injection exerts its bactericidal action by inhibiting bacterial cell wall synthesis, thus killing the bacteria. As a result, it treats bacterial infections.
Inform the doctor if you do not feel better after completing the whole course of treatment. You must also notify your doctor if your symptoms worsen while using this medication.
Ceftox 1 gm Injection is an antibiotic used to treat bacterial infections only. Ceftox 1 gm Injection does not treat a viral infection like the flu or a common cold.
Ceftox 1 gm Injection may cause diarrhoea as a side effect. If you have diarrhoea or soft stools, consult your doctor. Do not use anti-diarrheal medicine unless the doctor tells you to.
You are recommended to take Ceftox 1 gm Injection for as long as it is advised by your doctor for effective results. If your symptoms continue or worsen, seek further advice from your doctor.
Inappropriate use of antibiotics means using them when they are not necessary, such as for viral infections (like colds or the flu), stopping the treatment early, or using the wrong antibiotic for a specific infection. This can lead to antibiotic resistance.
Antibiotic resistance occurs when bacteria change in a way that reduces the effectiveness of antibiotics. As a result, the drugs no longer kill the bacteria, making infections more difficult to treat. This resistance can develop from overusing or misusing antibiotics, like taking them unnecessarily or not finishing the prescribed course.
No, Ceftox 1 gm Injection is not the same as penicillin. Ceftox 1 gm Injection contains ceftriaxone, a cephalosporin antibiotic, while penicillin belongs to a different class of antibiotics. Both treat bacterial infections, but they work in different ways.
Ceftox 1 gm Injection is effective when taken as per the dose advised by your doctor for the recommended duration. Even if you start feeling better, do not stop the treatment early. Stopping it early may cause the symptoms to return or worsen.
Ceftox 1 gm Injection will only be administered by a healthcare professional. Do not self-administer.
Ceftox 1 gm Injection usually begins to work shortly after you start taking it. However, it may take few days to eliminate all harmful bacteria and improve your symptoms.
Ceftox 1 gm Injection causes side fever, nausea, vomiting, dizziness, soft stools or diarrhoea, skin rash, swelling, tenderness, or pain at the site of injection. These do not require any medical treatment as they will gradually reduce over time. However, please contact a doctor if these side effects persist or worsen.
While alcohol does not directly stop Ceftox 1 gm Injection from working, it can dehydrate your body and strain your organs while you are fighting an infection. It is best to avoid alcohol during treatment. Talk to your doctor.
Ceftox 1 gm Injection is generally used during pregnancy only when clearly needed and prescribed by a physician. Your doctor will weigh the benefits against any potential risks to the baby. Talk to your doctor.
Yes, like many strong antibiotics, Ceftox 1 gm Injection can disrupt the natural balance of bacteria in your body, which may lead to oral thrush or a vaginal yeast infection. Talk to your doctor if you notice unusual white patches in your mouth or itching.
Yes, Ceftox 1 gm Injection may be used in newborns, including premature infants, and children to treat serious bacterial infections such as sepsis and meningitis. In neonates and premature infants, the dose and dosing interval are carefully determined by the doctor based on the baby's age, weight, kidney function, and severity of infection. Talk to your doctor for specific advice about your child's treatment.
If you are receiving Ceftox 1 gm Injection for an extended period, your doctor may order regular blood and kidney function tests to monitor how your body is handling the medication. Talk to your doctor.

Disclaimer

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.12713 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A682765 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Cefotaxime Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Cefotaxime Cefotaxime. 2015. [Accessed on 29 Mar. 2019]Check here
  6. Cefotaxime 500mg, 1g Powder for solution for injection or infusion PL 29831/0030 — Summary of Product Characteristics (SmPC) — (emc) [Internet]. Medicines.org.uk; 2025 [Accessed on 29 September 2025]Check here
  7. CP Pharmaceuticals Ltd; Electronic Medicines Compendium (EMC) [Revised on March 2024] [Accessed on 18th May 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - CEF1654
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