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  3. Ceftolon-SB 1.5 Injection 1's

Ceftolon-SB 1.5 Injection 1's, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ceftolon-SB 1.5 Injection is used to treat bacterial infections. It contains Ceftriaxone and Sulbactam which work by inhibiting the growth of infection-causing bacteria. In some cases, this medicine may cause side effects such as pain and swelling at the injection site, skin rash, diarrhoea, nausea, vomiting and black/tarry stools. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

CEFTRIAXONE-1000MG + SULBACTAM-500MG

Manufacturer/Marketer :

Intra Life Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Ceftolon-SB 1.5 Injection

Ceftolon-SB 1.5 Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Ceftolon-SB 1.5 Injection is a combination of two medicines: Ceftriaxone and Sulbactam. Ceftriaxone is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (ceftriaxone).

Ceftolon-SB 1.5 Injection will be administered by a healthcare professional, so do not self-administer. The common side effects of Ceftolon-SB 1.5 Injection include pain and swelling at the injection site, skin rash, diarrhea, nausea, vomiting and black/tarry stools. These side effects are usually mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take Ceftolon-SB 1.5 Injection if you are allergic to penicillin or any cephalosporin antibiotic or its contents. Before taking Ceftolon-SB 1.5 Injection, inform your doctor if you have kidney problems, liver disease, diabetes or using other antibiotics. Do not discontinue or abruptly stop using Ceftolon-SB 1.5 Injection as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). Before taking Ceftolon-SB 1.5 Injection, inform your doctor if you have an electrolyte imbalance, seizures, or gastrointestinal diseases. Ceftolon-SB 1.5 Injection is probably safe when used in children, pregnant women, breastfeeding mothers and the elderly. Ceftolon-SB 1.5 Injection may not interact with alcohol. Ceftolon-SB 1.5 Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Ceftolon-SB 1.5 Injection

Treatment of Bacterial infections.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Ceftolon-SB 1.5 Injection will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Ceftolon-SB 1.5 Injection contains Ceftriaxone and Sulbactam. Ceftriaxone is a cephalosporin antibiotic, whereas Sulbactam is a beta-lactamase inhibitor. Ceftolon-SB 1.5 Injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple serious bacterial infections, including infections of the bloodstream (septicemia), bones (osteomyelitis), the heart valves (endocarditis), the membranes protecting the brain (meningitis), acute bacterial otitis media (infection of the middle ear) and the lining of the abdomen (peritonitis) and to prevent and treat infections following surgeries.

How Ceftolon-SB 1.5 Injection Works

Ceftolon-SB 1.5 Injection is a combination of two medicines: Ceftriaxone and Sulbactam. Ceftriaxone is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (ceftriaxone).

Storage

stored at room temperature below 30°C

What if I have taken an overdose of Ceftolon-SB 1.5 Injection

Since Ceftolon-SB 1.5 Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience symptoms of overdose such as nausea, vomiting, and diarrhoea.

Drug Warnings

It is not recommended to take Ceftolon-SB 1.5 Injection if you are allergic to penicillin, any cephalosporin antibiotic, or its contents. Before taking Ceftolon-SB 1.5 Injection, inform your doctor if you have kidney problems, liver disease, diabetes or using other antibiotics. Do not discontinue or abruptly stop using Ceftolon-SB 1.5 Injection as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). Before taking Ceftolon-SB 1.5 Injection, inform your doctor if you have an electrolyte imbalance, seizures, or gastrointestinal diseases. Ceftolon-SB 1.5 Injection is probably safe when used in children, pregnant women, breastfeeding mothers and the elderly. Ceftolon-SB 1.5 Injection may not interact with alcohol. Ceftolon-SB 1.5 Injection may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Alterations in prothrombin time (a test used to check for bleeding problems) have been reported in patients receiving this medicine. Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile, and you may experience severe diarrhoea.

Drug-Drug Interactions

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CeftriaxoneCalcium chloride
Critical
CeftriaxoneCalcium gluconate
Critical

Drug-Drug Interactions

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CeftriaxoneCalcium chloride
Critical
How does the drug interact with Ceftolon-SB 1.5 Injection:
Co-administration of Calcium chloride with Ceftolon-SB 1.5 Injection can increase the risk of side effects.

How to manage the interaction:
Taking Ceftolon-SB 1.5 Injection with Calcium chloride is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCalcium gluconate
Critical
How does the drug interact with Ceftolon-SB 1.5 Injection:
Co-administration of Calcium gluconate with Ceftolon-SB 1.5 Injection can increase the risk of adverse effects.

How to manage the interaction:
Taking Ceftolon-SB 1.5 Injection with Calcium gluconate is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCholera, live attenuated
Severe
How does the drug interact with Ceftolon-SB 1.5 Injection:
Taking the cholera vaccine after or along with Ceftolon-SB 1.5 Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Ceftolon-SB 1.5 Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. To ensure adequate vaccine response, you should not receive cholera vaccine, live until at least 14 days after you complete your antibiotic therapy. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Ceftolon-SB 1.5 Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid alcoholic beverages with Ceftolon-SB 1.5 Injection as they can make you dehydrated and may affect your sleep.  This can make it harder for your body to aid the Ceftolon-SB 1.5 Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Ceftolon-SB 1.5 Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advisable to avoid alcohol consumption to prevent unintended side effects.

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Pregnancy

Caution

Ceftolon-SB 1.5 Injection is not recommended for use in pregnancy unless absolutely necessary. Inform your doctor if you are pregnant. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Ceftolon-SB 1.5 Injection is not recommended for use in breastfeeding unless absolutely necessary. Inform your doctor if you are breastfeeding. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Ceftolon-SB 1.5 Injection may decrease your alertness and vision or make you sleepy and dizzy. Do not drive if these symptoms occur after receiving this medicine.

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Liver

Caution

Ceftolon-SB 1.5 Injection should be used with caution if you have liver function impairment due to the increased risk of worsening your condition. Regular monitoring of liver function tests, appropriate dose adjustments or replacement with a suitable alternative medicine may be required in some cases based on your clinical condition.

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Kidney

Caution

Ceftolon-SB 1.5 Injection should be used with caution if you have a history of renal function impairment due to the increased risk of severe side effects. Close monitoring of kidney function, appropriate dose adjustments or replacement with alternative medicine may be required in some cases based on your clinical condition.

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Children

Caution

Ceftolon-SB 1.5 Injection is probably safe when used in children. However, your doctor may adjust the dose based on age, body weight and health condition of your child.

Have a query?

FAQs

Ceftolon-SB 1.5 Injection is used to treat bacterial infections.

Ceftolon-SB 1.5 Injection contains Ceftriaxone and Sulbactam. Ceftriaxone reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme bacteria produce to destroy antibiotics. Sulbactam enhances the activity of ceftriaxone.

Common side effects of Ceftolon-SB 1.5 Injection are pain and swelling at the injection site, skin rash, diarrhea, nausea, vomiting and black/tarry stools. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.

Ceftolon-SB 1.5 Injection should be avoided in conditions like gastrointestinal diseases, liver diseases, kidney diseases, seizure disorders, bleeding disorders, antibiotic resistance and bleeding disorders.

Do not stop taking Ceftolon-SB 1.5 Injection suddenly because your symptoms may improve before the infection is completely cured. Complete the full course of treatment even if you feel better.

People allergic to penicillin should not take Ceftolon-SB 1.5 Injection as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Ceftolon-SB 1.5 Injection contains ceftriaxone, which has a similar structure to that of penicillin.

Ceftolon-SB 1.5 Injection may cause allergic reactions, such as skin rashes, swelling, difficulty breathing, or in rare cases, anaphylaxis (a severe, rapid allergic reaction). If you have a history of allergies to antibiotics, please inform your doctor before using Ceftolon-SB 1.5 Injection.

Ceftolon-SB 1.5 Injection may cause diarrhoea as a side effect. Like other antibiotics, it can disrupt the normal balance of bacteria in your gut. To help manage antibiotic-related diarrhoea, make sure to stay hydrated, consider taking probiotics, avoid dairy, and limit high-fibre foods. If diarrhoea is severe or persistent, please consult your doctor.

Ceftolon-SB 1.5 Injection usually starts working within a few hours after you take it. However, you will likely notice an improvement in your symptoms within the first few days of treatment, depending on the severity of the infection.

If you don't get better after using Ceftolon-SB 1.5 Injection, it could mean that the infection is resistant to the antibiotic or there might be complications. Please contact your doctor so they can assess your condition and adjust your treatment if needed. The doctor may test for antibiotic resistance, try a different antibiotic, or investigate other possible causes.

Country of origin

India

Manufacturer/Marketer address

61/C, 1st Floor, 6th Main Road, 4th Phase, 7th Block, B.S.K. 3rd Stage, Bangalore - 560 085
Other Info - CEF1758

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:48 AM IST

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Reference

  1. https://www.csciencedirect.com/topics/chemistry/sulbactam
  2. https://www.medicines.org.uk/emc/product/1361/smpc#PRODUCTINFO

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