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  3. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection 1's

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Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection 1's, Pack of 1 INJECTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection belongs to the class of monoclonal antibodies used in the post-exposure treatment of mild to moderate respiratory illness caused by coronavirus infection. This combination medicine works by blocking the spike protein of the virus from attaching to the human receptor cell, thereby arresting the progress of the disease. Common side effects include nausea, diarrhoea, indigestion, vomiting, pain and soreness at the injection site.
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Composition :

CASIRIVIMAB-1200MG + IMDEVIMAB-1200MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection belongs to the group of monoclonal antibodies used in the post-exposure treatment of mild to moderate respiratory illness caused by COVID-19 in people aged 12 years or older, weighing at least 40kgs. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is used in non-hospitalised cases of COVID-19 that are at risk of progressing to severe disease. 

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection contains Casirivimab and Imdevimab which work by using proteins (monoclonal antibodies) that mimic the natural immune system of the body and fight off the harmful virus. They block the virus attachment and entry into the human cells, thereby preventing the progression of the illness.

A qualified healthcare professional will administer Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection. Do not self-administer. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection may cause certain common side effects such as redness, pain and soreness at the injection site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is not authorized for use in patients who require oxygen therapy or hospitalisation due to COVID-19.

Uses of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is used in the treatment of COVID-19. The detailed uses of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection are as follows:<br/>• Treatment of mild-to-moderate COVID-19: Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is used in the treatment of mild-to-moderate COVID-19 in adults and adolescents.<br/>• Post-exposure prophylaxis: Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is used post-exposure prophylaxis for individuals who are at high risk.<br/>

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Directions for Use

• Follow your doctor's instructions regarding dose and timing of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection for optimal results.• Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection contains monoclonal antibodies used in the post-exposure treatment of mild to moderate disease caused by SARS-CoV-2. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection works by using monoclonal proteins to imitate the natural defence mechanism of the body. The COVID virus contains a capsid with spike proteins, through which it penetrates into the body cells to cause infection. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection binds to the spike protein of the virus. Thereby blocking the spike protein of the virus from attaching to the human receptor cell and arresting the progress of the disease. Hence, Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection finds use in preventing the progression of mild to moderate covid cases to severe cases requiring hospitalisation. Thus, Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection finds use in reducing rates of hospitalisation. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection may also be used as post-exposure prophylaxis of coronavirus disease in people who are not fully vaccinated against COVID-19, people with immunocompromising conditions, and in those who are at high risk of being exposed to someone with COVID-19.

How Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection Works

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection contains Casirivimab and Imdevimab which work by using proteins (monoclonal antibodies) that mimic the natural immune system of the body and fight off the harmful virus. They block the virus attachment and entry into the human cells, thereby preventing the progression of the illness.

Storage

Store in a refrigerator between 2-8 degrees Celsius. Protect from light. Do not freeze. Do not shake. Keep out of reach of children.

What if I have taken an overdose of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is administered by a healthcare professional, so the risk of an overdose is low. However, if you experience any unusual symptoms, seek immediate medical attention.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed if you suffer from any chronic diseasea such as HIV, asthma, cancer, liver disease, kidney problems, heart disease, neurodevelopmental disorders, sickle cell disease or if you have recently had surgery, gastrostomy, tracheostomy or positive pressure ventilation. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor especially if you are on any radiotherapy, immunosuppressant drugs, blood thinners or any other medicines. Consult your doctor if you are planning to get pregnant or are breastfeeding. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is not meant for use as vaccination and in severe hospitalised cases.

Diet & Lifestyle Advise

  • Keep a healthy state of mind. Fear is one of the biggest causes of decreased immunity. See a therapist when you feel overwhelmed.
  • Meditation, music and yoga have also proven very effective in helping with mental health.
  • Keep yourself at a safe distance from people.
  • Always sneeze or cough into your elbow and keep a handkerchief on you.
  • Wash your hands with soap and water and keep yourself clean.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.
  • Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.
  • Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.

Habit Forming

No

Therapeutic Class

MONOCLONAL ANTIBODIES
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Alcohol

Caution

It is not recommended to consume alcohol with Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Not enough studies exist to ascertain the effect of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection on pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Not enough studies exist to ascertain the effect of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection on nursing. Please consult your doctor in case of any concerns.

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Driving

Caution

It is not known if Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection affects your ability to drive. Drive only if you are alert.

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Liver

Caution

Exercise caution before using Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Caution

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is not recommended for use in children below 12years. Please consult your doctor if you have any concerns.

FAQs

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection belongs to the group of monoclonal antibodies used in the post-exposure treatment of mild to moderate respiratory illness caused by COVID-19 in people aged 12 years or older, weighing at least 40kgs. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is used in non-hospitalised cases of COVID-19 that are at risk of progressing to severe disease.

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection works by inducing an antibody response in the body by instilling monoclonal antibodies that mimic the natural defences of the body and block the spike protein of the virus from attaching to body cells, thus arresting the progression of the disease.

Advanced age, obesity, chronic kidney disease, lung disease, sickle cell disease, neurodevelopmental disorders (for example cerebral palsy) and diseases of metabolism are high-risk factors for disease progression.

Not enough literature exists to ascertain the effects of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection on fertility. Please consult your doctor in case of any concerns.

Covid-19 spreads through respiratory droplets when in close or direct contact with an infected person. The virus can spread through an infected person’s sneeze or cough. The virus can also be transmitted by touching any contaminated surfaces and then touching the nose, mouth or eyes without washing the hands.

Vaccines stimulate the body to make its own antibodies against infection. On the other hand, monoclonal antibodies deliver lab-made antibodies against the virus.

Patients with a high risk of developing COVID-19 disease means, those who have certain underlying medical conditions or factors that make them more likely to experience serious illness if they contract COVID-19. These conditions include advanced age, obesity, chronic kidney disease, lung disease, sickle cell disease, neurodevelopmental disorders (for example cerebral palsy) and diseases of metabolism.

An antibody cocktail is a combination of two or more monoclonal antibodies which are separately available but are mixed together. Hence, the name cocktail.

Before taking Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection, inform your doctor if you are allergic to Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection, if you are using prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products. Also, inform your doctor if you have been vaccinated against COVID-19. Discuss the severity and duration of your COVID-19 symptoms to ensure the treatment is appropriate for your condition and also let your doctor know if you are breastfeeding, pregnancy or planning pregnancy.

Monoclonal antibodies are proteins made in a laboratory meant to stimulate immune system. Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection is a treatment that contains two monoclonal antibodies. These antibodies work together to neutralize the SARS-CoV-2 virus by binding to different parts of the virus's spike protein, preventing it from entering human cells.

Monoclonal antibodies neutralize SARS-CoV-2 by binding to its spike protein, preventing virus entry into human cells and reducing viral load, potentially alleviating symptoms and reducing disease severity.

Monoclonal antibody therapy for COVID-19 should be administered as soon as possible and within 5-7 days of symptom onset. Starting the treatment early in the course of the infection is crucial for it to be effective in reducing the risk of severe illness, hospitalization, and death.

Certain individuals should avoid monoclonal antibody therapy for COVID-19, including those who, are allergic to monoclonal antibody treatment, having severe or critical COVID-19 requiring hospitalization, who are seropositive for SARS-CoV-2 antibodies, indicating previous infection. And inform your doctor if you are breastfeeding, pregnant or planning pregnancy. It's important to discuss your medical history and any concerns with your doctor before starting treatment. They can help determine if monoclonal antibody therapy is safe and appropriate for you.

Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection can be administered either intravenously (into a vein) or subcutaneously (under the skin) by a trained healthcare professional in a hospital. Do not self-administer.

If you have high blood pressure and diabetes, you are recommended to take the advice of your doctor before taking Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection. To avoid potential interactions.

The common side effects of Casirivimab / Imdevimab Combo Pack 2400 mg (Regn-COV2) Injection are redness, pain and soreness at the injection site. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CAS0159

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:56 AM IST

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Reference

  1. https://en.wikipedia.org/wiki/Casirivimab/imdevimab
  2. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-monoclonal-antibodies-treatment-covid-19
  3. https://www.regeneron.com/medicines/casirivimab-imdevimab
  4. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00382-5/fulltext
  5. https://www.regeneron.com/downloads/treatment-covid19-eua-fact-sheet-for-hcp.pdf
  6. https://www.regeneron.com/downloads/treatment-covid19-eua-fact-sheet-for-hcp.pdf
  7. https://www.regeneron.com/downloads/treatment-covid19-eua-fact-sheet-for-patient.pdf

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