CARDULES PLUS 10MG TABLET

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Composition:ATENOLOL-50MG+NIFEDIPINE-10MG

Prescription Medicine

CARDULES PLUS 10MG TABLET is used to treat hypertension (high blood pressure). It helps relax blood vessels and supports smooth blood flow. This lowers blood pressure and reduces cardiac strain. It reduces the risk of cardiovascular complications and supports heart health.

Written By Veda Maddala , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

ATENOLOL-50MG+NIFEDIPINE-10MG

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About CARDULES PLUS 10MG TABLET

CARDULES PLUS 10MG TABLET is used to treat hypertension (high blood pressure). Hypertension is a condition in which the blood exerts high pressure (force exerted by circulating blood) against the walls of blood vessels.

CARDULES PLUS 10MG TABLET contains atenolol and nifedipine, which work together to control high blood pressure. It helps relax blood vessels and improves blood flow throughout the body. It also supports better heart function and helps prevent chest pain.

Take CARDULES PLUS 10MG TABLET as advised by a doctor. You may experience nausea, tiredness, stomach upset/constipation, cold hands or feet, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, sleepiness, palpitations (pounding of the heart), and swelling of the ankles or feet. Talk to your doctor if you experience these side effects persistently.

Do not stop taking CARDULES PLUS 10MG TABLET without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of CARDULES PLUS 10MG TABLET can be prescribed accordingly. Reduce the amount of table salt (sodium chloride) in your diet.

Uses of CARDULES PLUS 10MG TABLET

CARDULES PLUS 10MG TABLET is used to treat hypertension (high blood pressure) and manage heart conditions. The detailed uses of CARDULES PLUS 10MG TABLET are as follows:

Hypertension: CARDULES PLUS 10MG TABLET lowers high blood pressure and minimises the risk of heart-related complications.

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Directions for Use

Take CARDULES PLUS 10MG TABLET with or without food or as advised by a doctor.
Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
Swallow the medicine as a whole with glass of water.
Do not crush, break, or chew it.

Key Benefits

Helps control and lower high blood pressure.
Reduces strain on the heart and blood vessels.
Supports better heart function.
Helps reduce the risk of serious cardiovascular events.
Promotes stable and steady heart function.
Helps reduce chest discomfort.
Lowers the frequency of angina (chest pain) episodes.

How CARDULES PLUS 10MG TABLET Works

CARDULES PLUS 10MG TABLET contains Atenolol (beta-blocker) and Nifedipine (calcium channel blocker). Atenolol works by reducing heart rate and improving the heart's efficiency in pumping blood throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

Storage

Store in a cool and dry place away from sunlight

Side effects of Cardules Plus 10mg Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Slow Heart Rate

Exercising regularly helps lower the risk of heart problems.
Maintain a healthy diet, including vegetables and fruits.
Rest well; get enough sleep.
Manage stress with yoga and meditation.
Limit alcohol and smoking.

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Abnormally Low Body Temperature

Gastrointestinal Discomfort

Eat slowly and chew your food well to avoid swallowing air, which can make stomach pain worse.
Instead of going long periods without eating, try having smaller meals or snacks throughout the day to stop too much stomach acid from building up and causing pain.
Stay away from fatty, fried, or spicy foods. Instead, eat more healthy, fibre-rich foods.
Drink plenty of water to help with digestion and avoid soda or alcohol, which can make stomach pain worse.
Try to manage stress with relaxation techniques, and see a doctor if stress leads to chronic stomach pain.
Try antacids or medications like proton pump inhibitors to protect your stomach.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Restlessness

Restlessness is related to mental health and needs medical attention if it's severe.
Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
Prevent smoking as it can impact your calmness of body and mind.
Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

What if I have taken an overdose of CARDULES PLUS 10MG TABLET

Do not take more than the prescribed dose of CARDULES PLUS 10MG TABLET as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not use CARDULES PLUS 10MG TABLET if you are allergic to CARDULES PLUS 10MG TABLET or any of its components.
Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems, and adrenal gland diseases.
Let your doctor know if you have anuria (kidneys aren't producing urine), a fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease that causes scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders, or asthma before starting CARDULES PLUS 10MG TABLET.
It is essential to let your doctor know if you are a breastfeeding mother before using CARDULES PLUS 10MG TABLET since Indapamide may pass into the breast milk.
Please ask your doctor if you plan to conceive or are pregnant before using CARDULES PLUS 10MG TABLET.
CARDULES PLUS 10MG TABLET can increase the chances of light-headedness, so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.
CARDULES PLUS 10MG TABLET is not recommended for people under 18 years of age.

Drug-Drug Interactions

NifedipineCarbamazepine

Critical

NifedipinePhenobarbital

Severe

Drug-Drug Interactions

NifedipineCarbamazepine

Critical

How does the drug interact with Cardules Plus 10mg Tablet:
Coadministration of Cardules Plus 10mg Tablet with Carbamazepine can reduce the blood levels of Cardules Plus 10mg Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Cardules Plus 10mg Tablet with Carbamazepine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

NifedipinePhenobarbital

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Phenobarbital can drastically lower Cardules Plus 10mg Tablet levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Cardules Plus 10mg Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

NifedipineEnzalutamide

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Taking Enzalutamide with Cardules Plus 10mg Tablet may decrease the blood levels of Cardules Plus 10mg Tablet, which may make Cardules Plus 10mg Tablet less effective in treating your condition.

How to manage the interaction:
Although taking Enzalutamide and Cardules Plus 10mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

NifedipineRifapentine

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Coadministration of Cardules Plus 10mg Tablet with Rifapentine can reduce the metabolism and increase the levels of Cilostazol in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Taking Cardules Plus 10mg Tablet with Rifapentine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of drowsiness, dizziness, confusion, headache, fever, chills, excessive sweating, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

NifedipineMorphine

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Coadministration of Cardules Plus 10mg Tablet and Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Cardules Plus 10mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

NifedipineItraconazole

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Cardules Plus 10mg Tablet's blood levels can rise when itraconazole and Cardules Plus 10mg Tablet are taken together.

How to manage the interaction:
Cardules Plus 10mg Tablet and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you develop dizziness or fainting, unexpected swelling of the hands, ankles, or feet, chest pain, or difficulty breathing, consult a doctor. Never discontinue taking a medication without consulting a doctor.

NifedipineRifampicin

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Coadministration of Cardules Plus 10mg Tablet with rifampicin can decrease the blood levels of Cardules Plus 10mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Cardules Plus 10mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

NifedipinePrimidone

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Coadministration of Cardules Plus 10mg Tablet with primidone may decrease the blood levels of Cardules Plus 10mg Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Cardules Plus 10mg Tablet with Primidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

NifedipineRifabutin

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Coadministration of Cardules Plus 10mg Tablet with Rifabutin may significantly reduces the blood levels of Cardules Plus 10mg Tablet which may make the medication less effective.

How to manage the interaction:
Taking Cardules Plus 10mg Tablet with Rifabutin together is usually avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

NifedipineVenetoclax

Severe

How does the drug interact with Cardules Plus 10mg Tablet:
Using Venetoclax together with Cardules Plus 10mg Tablet may significantly increase the blood levels and effects of Venetoclax.

How to manage the interaction:
Although there is a possible interaction between Cardules Plus 10mg Tablet and Venetoclax, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your blood cells. Your doctor can recommend other options that won't cause any problems. If you notice any of these symptoms - like feeling sick, kidney problems, or stomach issues - make sure to call a doctor right away. They can help you with things like tiredness, anemia, or bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Diet:

Limit salt intake to 2300 mg per day or less, ideally 1500 mg.
Include omega-3–rich foods to support heart health.
Use healthy cooking oils like olive, soybean, canola, or coconut oil.

Weight and Activity:

Maintain a healthy body weight with a BMI (body mass index) between 19.5 and 24.9
Exercise for at least 150 minutes per week, such as 30 minutes on most days.

Habits:

Limit alcohol to one drink per day for women and two for men.
Quit smoking to reduce heart disease risk.

Stress and Monitoring:

Manage stress by spending time with loved ones and practising relaxation.
Monitor blood pressure daily and consult your doctor if fluctuations occur.

Habit Forming

Therapeutic Class

[ANTI- HYPERTENSIVES]

Alcohol

Unsafe

Alcohol may lower your blood pressure. It would help if you avoided or limit consuming alcohol whilst taking this medicine.

Pregnancy

Unsafe

CARDULES PLUS 10MG TABLET contains atenolol, a category D pregnancy drug, and it may cause fetal defects in the baby.

Breast Feeding

Unsafe

Do not take CARDULES PLUS 10MG TABLET as it may pass through the breast milk.

Driving

Unsafe

CARDULES PLUS 10MG TABLET may cause side effects such as dizziness, drowsiness, which could affect your ability to drive.

Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before using CARDULES PLUS 10MG TABLET.

Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before using CARDULES PLUS 10MG TABLET.

Children

Unsafe

CARDULES PLUS 10MG TABLET is not recommended for use in people below 18 years of age.

Heart

Safe if prescribed

CARDULES PLUS 10MG TABLET is generally safe for heart patients if prescribed, but should be used under medical supervision.

Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as CARDULES PLUS 10MG TABLET may increase the risk of side effects.

FAQs

What is the use of CARDULES PLUS 10MG TABLET?

CARDULES PLUS 10MG TABLET is used to treat hypertension (high blood pressure).

How does CARDULES PLUS 10MG TABLET work?

CARDULES PLUS 10MG TABLET consists of Atenolol and Nifedipine medicines. Atenolol is a beta-blocker and treats high blood pressure, angina (chest pain), and uneven heartbeats (arrhythmias) by reducing the heart rate and making the heart pump blood throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

In what conditions should I stay cautious while using CARDULES PLUS 10MG TABLET?

It is advised to consult your doctor before taking CARDULES PLUS 10MG TABLET if you have a history of severe kidney or liver diseases, low potassium levels (hypokalaemia), diabetes, gout, abnormal heart rhythms, thyroid disorders and asthma.

Can CARDULES PLUS 10MG TABLET cause sudden drop in blood pressure ?

Yes, CARDULES PLUS 10MG TABLET contains nifedipine, which can cause a sudden drop in blood pressure, especially when you start taking CARDULES PLUS 10MG TABLET, to avoid a sudden drop, please get up gently when sitting down to avoid dizziness.

Do I need to take CARDULES PLUS 10MG TABLET even if my blood pressure becomes normal?

Even though your blood pressure becomes normal after using CARDULES PLUS 10MG TABLET, it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

What if I forgot to take CARDULES PLUS 10MG TABLET?

If you forget to take CARDULES PLUS 10MG TABLET at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In

Other Info - CAR0003

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Mar 13, 2026 | 8:42 AM IST

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