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  3. Capmide 40 Softgel Capsule 4's

Capmide 40 Softgel Capsule 4's, Pack of 4 CapsuleS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Capmide 40 Softgel Capsule is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Composition :

ENZALUTAMIDE-40MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Capmide 40 Softgel Capsule

Capmide 40 Softgel Capsule belongs to a group of medicines known as androgen receptor inhibitors. It is used to treat prostate cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Capmide 40 Softgel Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Use this medicine as directed by your doctor. You may sometimes experience trouble breathing (pneumonia), weakness or feeling more tired than usual, back pain, diarrhoea, pain in your joints, swelling (in your hands, arms, legs or feet), muscle or bone pain, muscle weakness, headache, cold-like symptoms, dizziness, high blood pressure and trouble falling or staying asleep (insomnia). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Enzalutamide is only for use in men. Men using this Capmide 40 Softgel Capsule must use effective birth control whenever they have sex during your treatment and for three months after their final dose. In rare cases, Capmide 40 Softgel Capsule may cause seizures, so tell your doctor if you have or have ever had seizures. Because of the risk of seizure associated with Capmide 40 Softgel Capsule use, patients should be advised of the risk of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Consumption of alcohol is strictly avoided.

Uses of Capmide 40 Softgel Capsule

Capmide 40 Softgel Capsule is used in the treatment of Prostate Cancer. The detailed uses of Capmide 40 Softgel Capsule are as follows:<br/> • Metastatic castration-resistant prostate cancer (mCRPC): Capmide 40 Softgel Capsule is used to treat prostate cancer that continues to progress despite low testosterone levels. It is typically prescribed when the cancer has spread to other parts of the body and no longer responds to hormone therapy.<br/> • Non-metastatic castration-resistant prostate cancer (nmCRPC): Capmide 40 Softgel Capsule is used in patients whose prostate cancer has not yet spread but is no longer responding to medical or surgical treatments that lower testosterone.<br/> • Hormone-sensitive metastatic prostate cancer: Capmide 40 Softgel Capsule is used in combination with androgen deprivation therapy (ADT) to treat prostate cancer that has spread but still responds to hormone-lowering treatments.<br/>

Directions for Use

  • Capmide 40 Softgel Capsule can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Capmide 40 Softgel Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Capmide 40 Softgel Capsule contains Enzalutamide, which belongs to a group of medicines known as androgen receptor inhibitors. Most prostate cancers require testosterone to grow. In men, the testicles produce the majority of testosterone. Adrenal glands (Just above each kidney) produce a small quantity of testosterone. Enzalutamide is preventing testosterone from reaching cancer cells in the prostate. This can inhibit the growth of the cancer and even cause it to shrink.

How Capmide 40 Softgel Capsule Works

Capmide 40 Softgel Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Storage

• Store in a cool and dry place away from sunlight.• Keep Capmide 40 Softgel Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Capmide 40 Softgel Capsule
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.

What if I have taken an overdose of Capmide 40 Softgel Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Capmide 40 Softgel Capsule may include seizures. Seek immediate medical attention if you observe any symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Capmide 40 Softgel Capsule if you are allergic or hypersensitive to any component present in it. You must take Enzalutamide according to the instructions your doctor or pharmacist gives you. You must take Enzalutamide exactly as prescribed by your doctor or pharmacist. You must take the correct dose, not more or less. Consult your healthcare team before discontinuing Capmide 40 Softgel Capsule or missing a dose. Talk to your doctor before taking Capmide 40 Softgel Capsule if you have severe allergic reactions to medicines or foods or suffer from any medical illness. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Drug-Drug Interactions

verifiedApollotooltip
EnzalutamideRanolazine
Critical
EnzalutamideZiprasidone
Critical

Drug-Drug Interactions

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EnzalutamideRanolazine
Critical
How does the drug interact with Capmide 40 Softgel Capsule:
Taking Capmide 40 Softgel Capsule may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Capmide 40 Softgel Capsule with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideZiprasidone
Critical
How does the drug interact with Capmide 40 Softgel Capsule:
Taking Capmide 40 Softgel Capsule with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Capmide 40 Softgel Capsule with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideLurasidone
Critical
How does the drug interact with Capmide 40 Softgel Capsule:
Co-administration of Lurasidone with Capmide 40 Softgel Capsule may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Capmide 40 Softgel Capsule is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideDronedarone
Critical
How does the drug interact with Capmide 40 Softgel Capsule:
Co-administration of Capmide 40 Softgel Capsule and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Capmide 40 Softgel Capsule and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideRegorafenib
Critical
How does the drug interact with Capmide 40 Softgel Capsule:
Taking Capmide 40 Softgel Capsule with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Capmide 40 Softgel Capsule with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideMoxifloxacin
Severe
How does the drug interact with Capmide 40 Softgel Capsule:
Using Moxifloxacin together with Capmide 40 Softgel Capsule can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Capmide 40 Softgel Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience feeling dizziness, shortness of breath, or heart palpitations, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
EnzalutamideTofacitinib
Severe
How does the drug interact with Capmide 40 Softgel Capsule:
Co-administration of Capmide 40 Softgel Capsule and Tofacitinib may decrease the blood levels of Tofacitinib, which may make Tofacitinib less effective.

How to manage the interaction:
Although taking Capmide 40 Softgel Capsule and Tofacitinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
EnzalutamideApremilast
Severe
How does the drug interact with Capmide 40 Softgel Capsule:
Coadministration of Capmide 40 Softgel Capsule with apremilast may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Apremilast and Capmide 40 Softgel Capsule together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
EnzalutamideLapatinib
Severe
How does the drug interact with Capmide 40 Softgel Capsule:
When Lapatinib is taken with Capmide 40 Softgel Capsule, this could reduce the effects of lapatinib and its blood levels. Additionally, taking these medications together may enhance Capmide 40 Softgel Capsule's effects and blood levels.

How to manage the interaction:
Co-administration of Capmide 40 Softgel Capsule with Lapatinib can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms - like Seizures, exhaustion, fatigue, constipation, discomfort in the muscles or bones, hot flushes, swelling, tingling or prickling, headaches, dizziness, sleeplessness, anxiety, and increased blood pressure, consult a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideEverolimus
Severe
How does the drug interact with Capmide 40 Softgel Capsule:
Taking Capmide 40 Softgel Capsule with Everolimus may decrease the blood levels of Everolimus, which may make Everolimus less effective in treating the condition.

How to manage the interaction:
Although taking Capmide 40 Softgel Capsule and Everolimus together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Capmide 40 Softgel Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Capmide 40 Softgel Capsule.

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Pregnancy

Not applicable

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Not applicable

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Unsafe

Capmide 40 Softgel Capsule may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

bannner image

Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

bannner image

Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

bannner image

Children

Unsafe

The safety and effectiveness of Capmide 40 Softgel Capsule in pediatric patients have not been established.

Have a query?

FAQs

Capmide 40 Softgel Capsule is used to treat prostate cancer in men.

Most prostate cancers require testosterone to grow. Capmide 40 Softgel Capsule contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Capmide 40 Softgel Capsule can slow the cancer&#039;s growth and cause it to shrink.

Capmide 40 Softgel Capsule is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.

In some cases, Capmide 40 Softgel Capsule may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.

Enzalutamide, a prostate cancer medication, is used to treat prostate cancer.

Seizures may occur in patients receiving Capmide 40 Softgel Capsule. So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.

Yes, Enzalutamide was generally a well-tolerated medication. Take Capmide 40 Softgel Capsule pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Capmide 40 Softgel Capsule unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Capmide 40 Softgel Capsule therapy or adjust your Capmide 40 Softgel Capsule dose.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CAP0231

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 23, 2025 | 8:42 AM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a612033.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203415lbl.pdf
  3. https://aarkpharma.com/product/obnyx-enzalutamide-price-in-india/
  4. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/enzalutamide
  5. https://www.drugs.com/drug-interactions/enzalutamide-index.html

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