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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Canrib Tablet 60's is used to treat various cancers, including ovarian, breast, pancreatic, and prostate. It contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage. Avoid taking this medication if you are pregnant or breastfeeding because this can cause harmful effects on the unborn baby. Both women and men using this should use birth control to avoid pregnancy.

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Whats That

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Composition :

OLAPARIB-100MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Canrib Tablet 60's

Canrib Tablet 60's is an 'anti-cancer' drug used to treat various cancers, including ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.

Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

To treat your condition effectually, continue taking Canrib Tablet 60's for as long as your doctor has prescribed. Do not stop using the Canrib Tablet 60's midway. Talk to your doctor before taking Canrib Tablet 60's if you have severe allergic reactions to Canrib Tablet 60's or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Canrib Tablet 60's if you are pregnant or breastfeeding because this Canrib Tablet 60's can cause harmful effects on the unborn baby. Both women and men using this Canrib Tablet 60's should use birth control to avoid pregnancy. While on Canrib Tablet 60's treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.

Uses of Canrib Tablet 60's

Canrib Tablet 60's is used in the treatment of Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. The detailed uses of Canrib Tablet 60's are as follows:<br/>• Ovarian Cancer: Canrib Tablet 60's helps in maintenance treatment for advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer after response to platinum-based chemotherapy and especially effective in patients with BRCA mutations or homologous recombination deficiency (HRD).<br/>• Breast Cancer: Canrib Tablet 60's is used for HER2-negative, BRCA-mutated metastatic or high-risk early breast cancer and used after chemotherapy and sometimes endocrine therapy.<br/>• Pancreatic Cancer: Canrib Tablet 60's helps in maintenance treatment for germline BRCA-mutated metastatic pancreatic cancer that hasn’t progressed after platinum-based chemotherapy.<br/>• Prostate Cancer: Canrib Tablet 60's is for BRCA-mutated metastatic castration-resistant prostate cancer, often after prior hormonal therapy.<br/>

Directions for Use

• Canrib Tablet 60's can be taken with or without food as prescribed by your doctor.• It is usually taken twice a day in the morning and evening, or as prescribed by your doctor.• Swallow the medicine as a whole with a glass of water.• Do not break, crush or chew Canrib Tablet 60's.

Medicinal Benefits

Canrib Tablet 60's belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate.  Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

How Canrib Tablet 60's Works

Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Canrib Tablet 60's out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Canrib Tablet 60's

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Canrib Tablet 60's or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Canrib Tablet 60's for as long as your doctor has prescribed. Do not stop Canrib Tablet 60's midway. Talk to your doctor before taking Canrib Tablet 60's if you have severe allergic reactions to Canrib Tablet 60's or other medicines or suffer from any medical illness. Avoid taking Canrib Tablet 60's if you are pregnant or breastfeeding because this Canrib Tablet 60's can cause harmful effects on the unborn baby. Both women and men using this Canrib Tablet 60's should use birth control to avoid pregnancy. Do not start Canrib Tablet 60's unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Canrib Tablet 60's and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Canrib Tablet 60's.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Canrib Tablet:
Taking Canrib Tablet with rifampicin can decrease the blood levels of Canrib Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Canrib Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Canrib Tablet:
Taking Armodafinil and Canrib Tablet may reduce the blood levels of Canrib Tablet, which may reduce the effect of Canrib Tablet.

How to manage the interaction:
Although there is a possible interaction between Armodafinil and Canrib Tablet, you can take these medicines together if prescribed by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without consulting a doctor.
How does the drug interact with Canrib Tablet:
Using adalimumab together with Canrib Tablet may increase the risk of infections.

How to manage the interaction:
Combining adalimumab and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
OlaparibMitotane
Severe
How does the drug interact with Canrib Tablet:
Using Mitotane together with Canrib Tablet can reduce the blood levels of Canrib Tablet.

How to manage the interaction:
Although taking Canrib Tablet and Mitotane together can evidently cause an interaction, it can be taken if your doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Canrib Tablet:
Using Posaconazole and Canrib Tablet can increase the blood levels of Canrib Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort.

How to manage the interaction:
Although there is an interaction between posaconazole and Canrib Tablet, it can be taken if advised by a doctor. However, if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.
OlaparibCobicistat
Severe
How does the drug interact with Canrib Tablet:
Using Cobicistat and Canrib Tablet can increase the blood levels of Canrib Tablet.This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Cobicistat and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Canrib Tablet:
Combining Canrib Tablet with Modafinil may significantly reduce the blood levels of Canrib Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Canrib Tablet and Modafinil, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Canrib Tablet:
Using Dronedarone and Canrib Tablet can increase the blood levels of Canrib Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Dronedarone and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibBCG vaccine
Severe
How does the drug interact with Canrib Tablet:
Combining BCG vaccine with Canrib Tablet can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Canrib Tablet and BCG vaccine, you can take these medicines together if prescribed by your doctor. If you notice any signs of infection, it's important to contact your doctor right away. They can provide the necessary help and treatment to address the issue. Do not discontinue any medications without first consulting your doctor.
OlaparibConivaptan
Severe
How does the drug interact with Canrib Tablet:
Using Conivaptan and Canrib Tablet can increase the blood levels of Canrib Tablet.This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Conivaptan and Canrib Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Canrib Tablet 60's.

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Pregnancy

Unsafe

Canrib Tablet 60's should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Canrib Tablet 60's and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Unsafe

Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.

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Driving

Caution

Canrib Tablet 60's may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Canrib Tablet 60's in pediatric patients have not been established.

Have a query?

FAQs

Canrib Tablet 60's is used to treat ovarian, breast, pancreatic, and prostate cancers.

Canrib Tablet 60's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Canrib Tablet 60's.

Yes, Canrib Tablet 60's can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Canrib Tablet 60's is not a traditional chemotherapy pill. It's a targeted therapy, also known as a PARP inhibitor, which works differently from chemotherapy.

When taking Canrib Tablet 60's, avoid or limit foods high in grapefruit or grapefruit juice, as these can interact with the medication. Additionally, consult your doctor or pharmacist for personalized dietary advice.

The duration of Canrib Tablet 60's treatment can vary depending on the type of cancer being treated and the patient's response to the medication. Generally, Canrib Tablet 60's is taken until disease progression, unacceptable toxicity, or completion of a specified treatment period. Therefore, follow your doctor's instructions carefully.

Before taking Canrib Tablet 60's, inform your doctor about all your medical conditions, sensitivities, and medications. Also, mention if you're pregnant, planning to become pregnant, or breastfeeding. This will ensure safe use and help avoid any potential interactions.

Canrib Tablet 60's can interact with other medications, so do not use any other medications unless your doctor advises. Your doctor will check for potential interactions and advise you on how to take them safely with Canrib Tablet 60's.

No, Canrib Tablet 60's is not recommended for use during pregnancy and breastfeeding, and it causes unwanted side effects. However, please consult your doctor if you have any concerns.

The common side effects of Canrib Tablet 60's are feeling very tired, pale skin, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Please consult your doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Adley Formulation, Sco- 42, Sector 12, Panchkula-134112, Haryana, India
Other Info - CAN0758

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