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compositionComposition:DIAZEPAM-10MG
prescription
Prescription Medicine
info
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Calmpose Injection 5 x 2 ml belongs to the class of benzodiazepines. It is used in the treatment of anxiety, muscle spasms, epilepsy/fits, sedation during surgery or dental procedures, and alcohol withdrawal syndrome. This medication relieves anxiety by raising the gamma-aminobutyric acid (GABA), a calming chemical mediator. Common side effects include drowsiness, fatigue, confusion, unsteadiness, or dizziness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

DIAZEPAM-10MG

Manufacturer/Marketer :

Ranbaxy Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Calmpose Injection 5 x 2 ml

Calmpose Injection 5 x 2 ml is a prescription injection used to treat severe anxiety, acute seizures, and muscle spasms. It is also commonly used to manage severe symptoms of alcohol withdrawal and to help calm patients immediately before medical procedures. This medication belongs to a group of drugs that help calm overactive nerve signals in the brain.

Because this medication is given as an injection, it is typically used for short-term or emergency treatment rather than on a daily, long-term schedule. Your healthcare provider will determine how often you need it to ensure safe and consistent results. Since it is injected directly into your body, food does not affect how well it works, but limiting caffeine and managing stress can greatly improve your treatment outcomes.

While this medicine is highly effective, it can cause common side effects like drowsiness, muscle weakness, and a feeling of unsteadiness. Most of these effects are mild and temporary, but you must contact your doctor immediately if you experience serious issues such as unusually slow breathing, severe confusion, or yellowing of your eyes or skin.

Do not take this if you have severe breathing difficulties, sleep apnea, myasthenia gravis, or severe liver damage. Before you receive this medication, tell your doctor if you have a history of kidney disease, depression, or struggles with alcohol or drug abuse, as these conditions require extra care.

This medicine interacts strongly with alcohol and other sedatives, which can dangerously slow your breathing and brain activity. If you are pregnant, breastfeeding, or an older adult, you must consult your doctor before receiving this treatment, as special precautions or lower doses are often necessary to keep you safe.

Uses of Calmpose Injection 5 x 2 ml

Your doctor may prescribe Calmpose Injection 5 x 2 ml to treat the following conditions:

  • Severe Anxiety: Helps calm the brain and nervous system quickly during acute panic or severe anxiety states.
  • Acute Seizures: Helps control and stop active, prolonged seizures or fits rapidly.
  • Severe Muscle Spasms: Relaxes tense, painful muscles caused by nervous system disorders or local trauma.
  • Alcohol Withdrawal Symptoms: Eases severe agitation, tremors, and hallucinations during the early stages of stopping alcohol.
  • Pre-Surgery Sedation: Helps calm patients and reduce anxiety immediately before a medical procedure or surgery.

Key Benefits

  • Rapid emergency relief: Because it is injected directly into the body, it enters your system immediately to halt active seizures or severe panic attacks.
  • Effective muscle relaxation: It eases painful, severe muscle stiffness and spasms, helping you move more comfortably.
  • Calming effect: It helps calm intense agitation and anxiety, making medical procedures much easier to undergo.
Side effects of Calmpose Injection 5 x 2 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Calmpose Injection 5 x 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Calmpose Injection 5 x 2 ml Works

Calmpose Injection 5 x 2 ml works by targeting specific chemical messengers in your brain. It enhances the activity of a natural calming substance called gamma-aminobutyric acid, or GABA. GABA acts as a natural brake system for your nerves, slowing down overactive electrical signals in the brain. When GABA activity is boosted, it helps quiet down excessive brain activity. This action helps to relieve severe anxiety, stop active seizures, and relax tight or spasming muscles throughout your body.
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Alcohol

Unsafe

Intake of alcohol can increase the side effects of Calmpose Injection 5 x 2 ml , like dizziness, drowsiness, and difficulty concentrating. In a few cases, people may also experience impaired thinking and judgment. Hence, avoid consuming alcohol while being treated with Calmpose Injection 5 x 2 ml .

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Pregnancy

Unsafe

Calmpose Injection 5 x 2 ml is recommended in pregnancy if clearly necessary, Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Calmpose Injection 5 x 2 ml .

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Breast Feeding

Unsafe

Calmpose Injection 5 x 2 ml may not be recommended in breastfeeding as it may harm your infant. Inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Calmpose Injection 5 x 2 ml .

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Driving

Unsafe

Calmpose Injection 5 x 2 ml may cause a reduction in mental awareness, affect concentration and may cause dizziness. Hence, avoid driving after receiving Calmpose Injection 5 x 2 ml .

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Liver

Unsafe

Calmpose Injection 5 x 2 ml is not recommended for use in people with severe liver disease. Inform your doctor if you have a history of liver disease or an ongoing liver problem. Your doctor may adjust the dose of Calmpose Injection 5 x 2 ml if necessary.

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Kidney

Caution

Inform your doctor if you have kidney problems or a history of kidney disease. Your doctor may adjust your dose depending upon your kidney condition.

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Children

Caution

The safety and effectiveness of Calmpose Injection 5 x 2 ml in neonates (30 days or less) have not been established. Your paediatrician will recommend this medicine based on the condition of your child.

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Heart

Caution

Inform your doctor if you have heart disease. Your doctor may adjust your dose depending upon your heart condition.

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Geriatrics

Consult your doctor

Limited information available about the use of Calmpose Injection 5 x 2 ml in geriatric patients. Please consult your physician.

What if I have taken an overdose of Calmpose Injection 5 x 2 ml

If you suspect an overdose, seek emergency medical care immediately. Signs of an overdose may include extreme drowsiness, slow reflexes, shallow or slow breathing, severe confusion, or loss of consciousness.

Diet & Lifestyle Advise

  • Avoid alcohol entirely: Combining alcohol with this medication can cause dangerously slow breathing, severe drowsiness, or even death.
  • Limit caffeine intake: Reduce your consumption of coffee, tea, and energy drinks, as caffeine can interfere with the calming effects of the medication.
  • Avoid hazardous activities: Do not drive, operate heavy machinery, or participate in dangerous activities until you are certain the sedative effects of the injection have completely worn off.
  • Maintain a symptom or anxiety diary: Track your symptoms, when they occur, and when you receive your injections. Sharing this information helps your doctor adjust your treatment plan effectively.

Health Queries

Can Calmpose Injection be used for mental depression?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

No. Calmpose Injection is used to treat conditions such as anxiety, muscle spasms, epilepsy or seizures, and alcohol withdrawal symptoms. It may also be used as a sedative before certain surgical or dental procedures. It is not indicated for the treatment of depression. If you are experiencing symptoms of depression, consult a psychiatrist or healthcare professional for proper evaluation and appropriate treatment. Self-medication is not recommended.
health query

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How Soon It Starts Working

The time required for Calmpose Injection 5 x 2 ml to start to work: Calmpose Injection 5 x 2 ml ideally shows its action within 1 to 3 minutes after administration. The time for which the effects of Calmpose Injection 5 x 2 ml last: The duration of action for Calmpose Injection 5 x 2 ml is clinically unknown.

What if you forget to take Calmpose Injection 5 x 2 ml

Since this medicine is usually given by a healthcare provider in specific medical situations, a missed dose is uncommon. However, if you are receiving this treatment on a set schedule and miss an appointment, contact your healthcare provider immediately to get instructions. Do not receive a double dose to make up for a missed one.

Storage

• Keep this medication stored at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the medicine before use: Healthcare professionals should ensure the injection solution is clear and free from visible particles or discolouration. Do not use the vial or ampoule if the solution appears cloudy, contains sediment, or the container is damaged.
  • Rotate injection sites: If Calmpose Injection 5 x 2 ml is given by intramuscular injection, rotate the injection site with each dose to help minimise pain, tissue irritation, and local reactions.
  • Use only as prescribed: This medicine may cause physical dependence if used for prolonged periods. It is generally intended for short-term or emergency use and should be used only under close medical supervision.
  • Watch for excessive drowsiness or breathing problems: Tell a family member or caregiver that you are receiving this medicine so they can seek urgent medical attention if you become unusually sleepy, difficult to wake, or develop slow or difficult breathing.
  • Do not stop treatment abruptly: If you have been receiving Calmpose Injection 5 x 2 ml regularly, do not discontinue it suddenly. Your doctor will gradually reduce the dose when appropriate to help prevent withdrawal symptoms, such as anxiety, tremors, or seizures.

Drug-Drug Interactions

verifiedApollotooltip
  • Opioid pain relievers or cough medicines: Taking these with Calmpose Injection 5 x 2 ml can lead to severe drowsiness, breathing failure, coma, or death.
  • Other sleeping medicines or anxiety drugs: Can cause extreme sedation and dangerously slow your central nervous system.
  • Stomach acid reducers (like cimetidine): May slow down how your body clears this medicine, increasing the risk of side effects.
DiazepamCodeine
Severe
DiazepamRemifentanil
Severe

Drug-Drug Interactions

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DiazepamCodeine
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Calmpose Injection 5 x 2 ml with codeine may cause serious side effects.

How to manage the interaction:
Consult your doctor if you are using Calmpose Injection 5 x 2 ml and codeine. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
DiazepamRemifentanil
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Remifentanil with Calmpose Injection 5 x 2 ml can increase the seriousness of side effects.

How to manage the interaction:
Although taking Calmpose Injection 5 x 2 ml and Remifentanil together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your health and talk to your doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
DiazepamHydrocodone
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Calmpose Injection 5 x 2 ml with hydrocodone may cause serious side effects.

How to manage the interaction:
Although there is a possible interaction, Calmpose Injection 5 x 2 ml should be taken with hydrocodone if prescribed by the doctor. Your doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
DiazepamDroperidol
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Droperidol can enhance the sedative effects of Calmpose Injection 5 x 2 ml causing excessively slow heart rate and low blood pressure, and using it with Calmpose Injection 5 x 2 ml may increase those risks.

How to manage the interaction:
Taking Calmpose Injection 5 x 2 ml with Droperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - a very slow heart rate, low blood pressure, an irregular heartbeat, sudden dizziness, feeling lightheaded, fainting, or a strange heartbeat - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
DiazepamKetamine
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Calmpose Injection 5 x 2 ml with Ketamine can increase the risk of CNS depression.

How to manage the interaction:
Taking Ketamine with Calmpose Injection 5 x 2 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DiazepamTramadol
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Calmpose Injection 5 x 2 ml with tramadol may cause serious side effects like respiratory distress or coma.

How to manage the interaction:
Consult the doctor if you are taking Calmpose Injection 5 x 2 ml and tramadol. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
DiazepamMethadone
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking of Calmpose Injection 5 x 2 ml with methadone may cause serious side effects like respiratory distress.

How to manage the interaction:
Although there is a possible interaction, Calmpose Injection 5 x 2 ml should be taken with methadone only if prescribed by the doctor. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
DiazepamFentanyl
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Calmpose Injection 5 x 2 ml and fentanyl together can increase the risk of side effects.

How to manage the interaction:
Although taking Fentanyl together with Calmpose Injection 5 x 2 ml can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you have sleepiness, difficulty concentrating, and impaired judgment. Do not stop taking any medication without consulting your doctor.
DiazepamOlanzapine
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Calmpose Injection 5 x 2 ml together with olanzapine can cause low blood pressure, weak pulse, shallow breathing, muscle weakness, drowsiness, dizziness and slurred speech.

How to manage the interaction:
Combining Olanzapine and Calmpose Injection 5 x 2 ml can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you. Do not stop using any medications without first talking to your doctor.
DiazepamSufentanil
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Sufentanil with Calmpose Injection 5 x 2 ml can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Calmpose Injection 5 x 2 ml with Sufentanil can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: May interfere with how your body processes this medicine, leading to higher levels in your blood and increased side effects.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Yes

Therapeutic Class

[ANXIOLYTICS]

FAQs

Calmpose Injection 5 x 2 ml belongs to a group of medications called benzodiazepine used to treat anxiety, muscle spasms, and epilepsy/seizures/fits. It can also be used as a sedative during surgery or dental procedure. Besides this, it is also used to manage alcohol withdrawal symptoms like agitation, tremor, or hallucinations.
Calmpose Injection 5 x 2 ml works by increasing levels of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps to relieve anxiety and stops seizure attacks (fits), and relaxes tense muscles.
Using Calmpose Injection 5 x 2 ml in patients with sleep apnoea syndrome (a condition where breathing stops for a short period of time when a person is sleeping) is contraindicated. So, it is advisable to inform the doctor if you are suffering from sleep apnoea syndrome.
Caffeine is a stimulant that may reduce the calming effects of Calmpose Injection 5 x 2 ml . So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea, cola or chocolate that contain caffeine. Avoid grapefruit juice as it may increase the amount of Calmpose Injection 5 x 2 ml in blood.
Calmpose Injection 5 x 2 ml usage is not recommended in people with hypersensitivity to diazepam, people with a phobia (a fear of a particular object or situation), difficulty breathing, porphyria (a disorder of the blood), sleep apnoea syndrome, acute narrow-angle glaucoma, and open-angle glaucoma unless the patient is receiving appropriate treatment.
No, you should not drive or operate machinery after receiving this medicine. It can cause heavy drowsiness, dizziness, and slow reflexes that make driving unsafe for several hours. Talk to your doctor about when it is safe for you to drive again.
This medicine is generally not recommended during pregnancy, especially during the first trimester or close to delivery, as it may harm the unborn baby. However, in emergency situations like severe seizures, your doctor will weigh the risks and benefits. Talk to your doctor if you are pregnant or planning to become pregnant.
No, you should completely avoid alcohol while this medicine is in your system. Combining alcohol with this injection can lead to dangerous sedation, severe breathing problems, or coma. Talk to your doctor if you have concerns about alcohol.
Yes, this medication belongs to a class of drugs that can be habit-forming, especially with prolonged use. It is typically prescribed for short-term or emergency situations to minimise this risk and is given under close medical supervision. Talk to your doctor if you have a history of substance abuse or are concerned about dependency.
Mild pain, swelling, or redness at the injection site is common and usually goes away on its own. If the pain becomes severe, does not improve, or if you notice signs of infection like warmth or pus, talk to your doctor right away.
Older adults are more sensitive to the sedative effects of this medicine, which can increase their risk of confusion, severe drowsiness, and accidental falls. Doctors often prescribe a lower dose and monitor elderly patients closely. Talk to your doctor for personalised guidance.
This medicine is processed slowly by the liver and can remain in your body for several days, although its active calming effects usually wear off much sooner. Talk to your doctor to understand how long it may affect you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6274 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 020124S032Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). About Diazepam - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Diazepam Diazepam. 2013. [Accessed on 22 Mar. 2019]Check here
  5. Jaberpreet S. Dhaliwal, Alan Rosani, Abdolreza Saadabadi. Diazepam. National Centre for Biotechnology. NLM. National Institute of Health. Statpearls. May 2022. [Accessed on 10th September 2022]Check here
  6. Accord. Electronic Medicines Compendium. [Revised in August 2020] [Accessed on 10th September 2022]Check here
  7. Accord. Electronic Medicines Compendium. [Revised in September 2019] [Accessed on 10th September 2022]Check here

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - CAL0054

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