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  3. C-Zone-TZ Injection 1.125 gm

C-Zone-TZ Injection 1.125 gm, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

C-Zone-TZ Injection 1.125 gm is an antibiotic medicine used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, and bone and joint infections. It contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, they help to treat bacterial infections.

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Composition :

CEFOPERAZONE-1000MG + TAZOBACTAM-125MG

Manufacturer/Marketer :

Rx Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About C-Zone-TZ Injection 1.125 gm

C-Zone-TZ Injection 1.125 gm belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, and bone and joint infections.

C-Zone-TZ Injection 1.125 gm contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, C-Zone-TZ Injection 1.125 gm helps to treat bacterial infections.

In some cases, C-Zone-TZ Injection 1.125 gm may cause side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of C-Zone-TZ Injection 1.125 gm in children below 12 years has not been established. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of C-Zone-TZ Injection 1.125 gm

C-Zone-TZ Injection 1.125 gm is used in the treatment of various moderate to severe bacterial infections. The detailed uses of C-Zone-TZ Injection 1.125 gm are as follows:<br/>• Treats gynaecological infections: C-Zone-TZ Injection 1.125 gm is effective in managing pelvic infections, including pelvic inflammatory disease and post-surgical infections in female reproductive organs.<br/>• Manages urinary tract infections (UTIs): C-Zone-TZ Injection 1.125 gm helps eliminate bacteria causing lower and upper UTIs, including complicated cases.<br/>• Prevents and treats postoperative infections: C-Zone-TZ Injection 1.125 gm is used to prevent and control infections that may arise after surgical procedures.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• C-Zone-TZ Injection 1.125 gm will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

C-Zone-TZ Injection 1.125 gm belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, bone and joint infections, and gonorrhoea. C-Zone-TZ Injection 1.125 gm contains Cefoperazone (cephalosporin antibiotic) and Tazobactam (beta-lactamase inhibitor). Cefoperazone kills the bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, C-Zone-TZ Injection 1.125 gm helps to treat bacterial infections.

How C-Zone-TZ Injection 1.125 gm Works

C-Zone-TZ Injection 1.125 gm contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, C-Zone-TZ Injection 1.125 gm helps to treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep C-Zone-TZ Injection 1.125 gm out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of C-Zone-TZ Injection 1.125 gm

As C-Zone-TZ Injection 1.125 gm is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of C-Zone-TZ Injection 1.125 gm may include neurological effects, including seizures.

Drug Warnings

Do not receive C-Zone-TZ Injection 1.125 gm if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of C-Zone-TZ Injection 1.125 gm in children below 12 years has not been established. Let the doctor know if you take prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical
CefoperazoneRifampicin
Severe

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical
How does the drug interact with C-Zone-TZ Injection 1.125 gm:
When BCG vaccine is used with C-Zone-TZ Injection 1.125 gm, its effectiveness may be reduced.

How to manage the interaction:
Taking C-Zone-TZ Injection 1.125 gm with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor
CefoperazoneRifampicin
Severe
How does the drug interact with C-Zone-TZ Injection 1.125 gm:
Taking C-Zone-TZ Injection 1.125 gm and Rifampicin together may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between C-Zone-TZ Injection 1.125 gm and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotics and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

C-Zone-TZ Injection 1.125 gm Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid/limit the consumption of alcohol.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving C-Zone-TZ Injection 1.125 gm. C-Zone-TZ Injection 1.125 gm should be used during pregnancy only if clearly needed.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving C-Zone-TZ Injection 1.125 gm. C-Zone-TZ Injection 1.125 gm should be used with caution in breastfeeding women.

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Driving

Consult your doctor

It is not known if C-Zone-TZ Injection 1.125 gm affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving C-Zone-TZ Injection 1.125 gm.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving C-Zone-TZ Injection 1.125 gm.

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Children

Caution

The safety and effectiveness of C-Zone-TZ Injection 1.125 gm in children below 12 years has not been established.

Have a query?

FAQs

C-Zone-TZ Injection 1.125 gm is used to treat Bacterial infections.

C-Zone-TZ Injection 1.125 gm works by inhibiting nucleopeptide synthesis in the bacterial cell wall. It also helps decrease bacterial resistance.

Pseudomembranous colitis, a severe inflammation of the inner lining of the large intestine, has been reported using cephalosporin antibiotics. Therefore, it is necessary to consider its diagnosis in patients who develop diarrhoea associated with antibiotic use.

Dyspepsia (indigestion) might be a side effect of C-Zone-TZ Injection 1.125 gm. To prevent indigestion, eat smaller, more frequent meals and chew your food slowly and thoroughly. However, if the condition persists or worsens, consult the doctor.

C-Zone-TZ Injection 1.125 gm may cause common side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

You should take C-Zone-TZ Injection 1.125 gm for as long as your doctor prescribes it, depending on the type and severity of your infection. It is typically taken for 4 to 14 days. If your symptoms do not improve or get worse, please contact your doctor immediately.

The use of C-Zone-TZ Injection 1.125 gm does not typically cause diarrhoea. However, if you experience diarrhoea unusually or have concerns, please consult your doctor.

C-Zone-TZ Injection 1.125 gm usually starts working within a few hours after taking it. However, the full effect may take a few days, depending on the infection and how your body responds to the medication. Always follow your doctor's instructions and let them know if you do not see any improvement in your symptoms.

If you don't get better after using C-Zone-TZ Injection 1.125 gm, it could be because the infection is resistant to the medication or there might be another underlying cause. Let your doctor know so they can adjust your dose or treatment, check for antibiotic resistance, or look into other possible causes. Always follow your doctor's advice and never stop the medication without consulting them first.

No, you should not stop taking C-Zone-TZ Injection 1.125 gm just because you feel better. It's important to finish the entire course of antibiotics as prescribed by your doctor, even if you start feeling better. Stopping early could cause the infection to return or make the bacteria resistant to the medication.

Country of origin

India

Manufacturer/Marketer address

487/25, First Floor, National Market, Opposite Prachin Shiv Mandir, Peeragarhi, New Delhi-110087, Delhi, India
Other Info - CZO0005

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:07 AM IST

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Reference

  1. https://www.biocon.com/docs/domestic-market-pi/ccd/CEGAVA%20TZ%201-125g%20-PI.pdf
  2. https://wellonapharma.com/product/finished/cefoperazone-and-tazobactam-injection
  3. https://www.arlakbiotech.com/product/cefoperazone-1000mg-tazobactam-125mg-tyzone-t-inj/

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