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compositionComposition:BUSERELIN-1MG
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Busarlin Injection 7 ml is indicated in women for the treatment of infertility and endometriosis. This medicine is also indicated in the treatment of prostate cancer (cancer of the prostate gland) in men who have not had testicles removed by surgery. It contains Buserelin, a synthetic version of the hormone that naturally occurs in the body. It works by stopping the production of natural hormones that control ovulation. It helps relieve symptoms of endometriosis by reducing the production of female sex hormones by acting on the pituitary gland. This medicine helps treat prostate cancer by reducing the production of testosterone and helps to stop the growth of cancer cells.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BUSERELIN-1MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Busarlin Injection 7 ml

Busarlin Injection 7 ml is an injectable prescription medication used to manage hormone-sensitive conditions, including advanced prostate cancer, endometriosis, and uterine fibroids. It is also utilised in assisted reproductive technologies, such as in vitro fertilisation (IVF), to regulate ovulation. By controlling the production of specific hormones in the body, this medicine helps reduce symptoms and slow the progression of these conditions.

Since this medication is given as an injection, food intake does not affect how it is absorbed. It must be injected consistently at the exact times directed by your healthcare provider to ensure your hormone levels remain stable. Making certain lifestyle adjustments, such as eating a nutrient-rich diet and engaging in regular physical activity, can further support your treatment outcomes.

While taking Busarlin Injection 7 ml, some people may experience mild side effects like hot flashes, headaches, or mild irritation at the injection site. However, if you experience more serious symptoms, such as severe mood changes, visual disturbances, or signs of an allergic reaction, you should consult your doctor immediately.

Before starting this medication, talk to your doctor if you have a history of depression, diabetes, high blood pressure, or bone thinning (osteoporosis). Do not take this if you are pregnant, breastfeeding, or experiencing unexplained vaginal bleeding.

This medicine can interact with certain other treatments, alcohol, and tobacco, which may increase your risk of side effects or lower the drug's effectiveness. Specific patient groups, including pregnant women, breastfeeding mothers, and elderly individuals, must consult their doctor to discuss the safety of this medication before use.

Uses of Busarlin Injection 7 ml

Busarlin Injection 7 ml may be prescribed to manage the following conditions:

  • Prostate Cancer: It lowers the production of testosterone, which helps slow down or stop the growth of hormone-dependent cancer cells in the prostate.
  • Endometriosis: It reduces estrogen levels, helping to shrink abnormal uterine tissue growing outside the womb and relieve chronic pelvic pain.
  • Uterine Fibroids: It decreases estrogen levels to shrink non-cancerous growths in the uterus, helping to reduce heavy menstrual bleeding and pelvic pressure.
  • Infertility Treatment (IVF): It temporarily suppresses your body's natural hormone cycle, allowing fertility specialists to precisely control and stimulate ovulation.

Key Benefits

Busarlin Injection 7 ml is a gonadotropin-releasing hormone (GnRH) analogue used to manage certain hormone-dependent conditions, including endometriosis, uterine fibroids, and advanced prostate cancer. It is also used in some assisted reproductive treatment protocols to regulate ovulation.

  • Helps Manage Endometriosis: Suppresses ovarian hormone production, which may reduce endometriosis-related pelvic pain and other symptoms.
  • Helps Reduce Fibroid-Related Symptoms: May reduce the size of uterine fibroids and help relieve heavy menstrual bleeding and related symptoms.
  • Supports Prostate Cancer Treatment: Reduces testosterone production, helping slow the growth of hormone-dependent prostate cancer and potentially relieve associated symptoms.
  • Helps Regulate Fertility Treatment Cycles: In assisted reproductive treatment, it can help control the timing of ovulation and support planned egg retrieval.
  • Provides Hormonal Disease Control: By suppressing the production of sex hormones, it helps manage conditions that depend on these hormones for their growth or activity.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Busarlin Injection 7 ml will be administered by a healthcare professional.
  • If you have been prescribed Busarlin Injection 7 ml to use at home, check the label for directions and use it as advised by the doctor. Choose an injection site such as the thigh, upper arm, or abdomen, pinch the skin, and inject the advised dose at a 45-degree angle slowly and steadily.
  • Rotate the injection site every time.
  • Do not inject into skin that is red, bruised, or hard.
  • Do not reuse or share needles.

How Busarlin Injection 7 ml Works

Busarlin Injection 7 ml contains buserelin. It belongs to a class of medicines called gonadotropin-releasing hormone (GnRH) analogues. It works by acting directly on the pituitary gland in the brain. When you first start using the medicine, it causes a brief, temporary increase in the hormones that stimulate the ovaries or testicles. With continuous use, however, the medicine desensitises the pituitary gland. This action stops the signals that tell your body to produce sex hormones. Consequently, oestrogen levels in women and testosterone levels in men drop significantly. Because conditions like prostate cancer, endometriosis, and uterine fibroids rely on these hormones to grow, lowering their levels helps control the disease and ease your symptoms.
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Alcohol

Consult your doctor

It is unknown if Busarlin Injection 7 ml interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Busarlin Injection 7 ml is not recommended during pregnancy as it may be harmful to the developing baby. Please consult the doctor if you are pregnant, think you may be pregnant or become pregnant while on treatment with Busarlin Injection 7 ml.

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Breast Feeding

Unsafe

Breastfeeding is not recommended during treatment with Busarlin Injection 7 ml as it might pass into the mother’s milk.

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Driving

Caution

Busarlin Injection 7 ml may cause dizziness, drowsiness, or blurred eyesight. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Limited information is available. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Limited information is available. Please consult the doctor if you have a kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Limited information is available. Please consult the doctor if you have any concerns.

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Heart

Caution

Busarlin Injection 7 ml may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Busarlin Injection 7 ml.

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Geriatrics

Caution

Busarlin Injection 7 ml should be used with caution in geriatric patients due to increased risk of age-related side effects. Therefore, please consult your doctor before giving Busarlin Injection 7 ml to elderly individuals.

What if I have taken an overdose of Busarlin Injection 7 ml

If you suspect an overdose, seek immediate medical attention or contact your local poison control centre. Watch for symptoms such as extreme fatigue, severe dizziness, or intense headache.

Diet & Lifestyle Advise

  • Support Your Bones: Because this medicine lowers sex hormone levels, it can lead to bone thinning. Ensure your diet includes plenty of calcium and vitamin D from dairy products, leafy greens, or supplements as recommended by your doctor.
  • Incorporate Weight-Bearing Exercise: Engage in regular, moderate weight-bearing exercises like brisk walking, jogging, or resistance training to help keep your bones strong.
  • Manage Hot Flashes: Dress in removable layers, keep your bedroom cool, and limit triggers like hot drinks, spicy foods, caffeine, and alcohol.
  • Monitor Heart Health: Hormone-suppressing therapies can occasionally affect your cholesterol and blood pressure. Eat a heart-healthy diet rich in whole grains, lean proteins, and vegetables, and get your blood pressure checked regularly.
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Have a query?

How Soon It Starts Working

The time required for Busarlin Injection 7 ml to start to work: The time required for Busarlin Injection 7 ml to show its action is not clinically established. The time for which the effects of Busarlin Injection 7 ml last: The duration of action for Busarlin Injection 7 ml is not clinically established.

What if you forget to take Busarlin Injection 7 ml

Inject the missed dose as soon as you remember. However, if it is nearly time for your next scheduled injection, skip the missed dose and continue with your regular schedule. Do not inject a double dose to make up for a forgotten one. Talk to your doctor or pharmacist if you frequently miss doses.

Storage

• Depending on the specific product guidelines, keep it either at room temperature (below 25°C/77°F) or in the refrigerator (between 2°C and 8°C).
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the Injection Before Use: Do not use the solution if it appears cloudy, discoloured, or contains visible particles.
  • Use Injection Sites as Directed: If you are administering repeated injections, follow your healthcare provider's instructions on changing injection sites to reduce local irritation or tissue damage.
  • Never Reuse Needles or Syringes: Use a new sterile needle and syringe for each injection and dispose of used sharps safely.
  • Monitor Blood Sugar if You Have Diabetes: Busarlin Injection 7 ml may affect glucose control in some people. Check your blood sugar as advised by your doctor and report significant changes.
  • Attend Regular Follow-Ups: Keep scheduled appointments so your doctor can monitor your response to treatment and, when appropriate, assess bone health and other effects of prolonged hormone suppression.

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines before using Busarlin Injection 7 ml:

  • Diabetes medications (including insulin and oral drugs): Busarlin Injection 7 ml may reduce the effectiveness of these medications, which can lead to high blood sugar levels.
  • Medicines that affect heart rhythm (such as antiarrhythmics): Combining these treatments can increase the risk of developing abnormal heart rhythms.

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verifiedApollotooltip

Certain foods, drinks, and lifestyle habits may affect your treatment with Busarlin Injection 7 ml:

  • Alcohol and smoking: Consuming alcohol or smoking while using this medicine can accelerate bone thinning and worsen side effects like hot flashes.

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Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Busarlin Injection 7 ml is used to treat Infertility, Endometriosis, and Prostate cancer.
Busarlin Injection 7 ml works by stopping the production of natural hormones that control ovulation and relieves symptoms of endometriosis by reducing the production of female sex hormones. It reduces the production of testosterone, thereby preventing the growth of prostate cancer.
Busarlin Injection 7 ml might cause menopausal symptoms such as hot flushes, dry vagina, increased sweating, loss of sex drive, or painful sexual intercourse in women. If these symptoms become serious or last longer than a few days, consult a doctor.
Busarlin Injection 7 ml might increase the risk of osteoporosis if used for a longer duration due to a lowering in the amount of bone mineral. However, this effect is reversible when the treatment is stopped. Consult a doctor if you experience bone or muscle discomfort, such as shoulder stiffness or pain that lasts longer than a few days.
Busarlin Injection 7 ml may increase the risk of heart rhythm problems. Inform the doctor if you have heart or blood vessel problems, including arrhythmia (heart rhythm problems), or if you are being treated with medicines for these conditions.
Busarlin Injection 7 ml may cause muscle or bone pain, including pain in the back or jaw. Consult the doctor if you experience muscle or bone pain; the doctor may prescribe painkillers.
You should call your doctor right away if you experience signs of allergic reactions such as rash, itching, hives, blisters and difficulty breathing. Also, inform your doctor if you experience chest pain, severe headache, fast/irregular heartbeat, severe dizziness, severe vomiting and vision changes.
A tumour flare reaction (TFR) is an immune response that can occur during cancer treatment, particularly with immunomodulatory drugs or immune checkpoint inhibitors. Yes, you may experience a tumour flare reaction (TFR) while on treatment with Busarlin Injection 7 ml. During the first month of Busarlin Injection 7 ml treatment, you might notice an increase in symptoms such as painful or difficult urination, blood in urine, weakness in your legs or sudden back or trunk pain. These are temporary and gradually reduce. However, if these symptoms persist, please contact your doctor immediately.
Yes, Busarlin Injection 7 ml can cause weight gain in some patients. It’s important to maintain a balanced diet by eating fruits, vegetables, whole grains, and lean proteins. Avoid processed foods, sugary snacks, and high-calorie beverages. Engage in regular physical activity.
As a diabetic, it's important to take extra precautions while using Busarlin Injection 7 ml as it may reduce the effect of drugs used to treat diabetes. Therefore, blood glucose levels should be checked regularly in diabetic patients. Be aware of symptoms like increased thirst, frequent urination, and unexplained weight changes, as these could indicate changes in your blood sugar levels. Consult your doctor if you have any concerns.
Yes, loss of interest in sexual activity is a side effect of Busarlin Injection 7 ml. Please consult your doctor if you experience this side effect.
Feeling exhausted is a common side effect of Busarlin Injection 7 ml. Take some rest and stay hydrated by drinking plenty of water. Consult your doctor if this side effect persists.
The interaction of alcohol with Busarlin Injection 7 ml is unknown. If you have any concerns, please discuss with your doctor.
The common side effects of Busarlin Injection 7 ml are diarrhoea, constipation, nausea, vomiting, abdominal pain, and headache. If any of these side effects persist or worsen, please consult your doctor.
For most patients, normal hormone production and fertility gradually return within a few weeks to several months after stopping the medication. Talk to your doctor to discuss your specific fertility timeline and reproductive plans.
Yes, many patients can safely inject this medication at home after receiving proper, thorough injection training from their healthcare provider. Do not attempt to self-inject until you feel completely confident in the process. Talk to your doctor or pharmacist if you need further guidance.
Yes, because this medicine temporarily lowers your sex hormone levels, mood swings, anxiety, and depressive feelings are recognised side effects. If you experience severe mood shifts, persistent sadness, or anxiety, talk to your doctor immediately.
Yes, even though this medicine is used to suppress hormone levels, it is not a reliable method of contraception. You must use a reliable, non-hormonal birth control method, such as condoms, during your treatment. Talk to your doctor to determine the best option for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - BUS0048
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