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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
BUPRIGESIC 0.6MG INJECTION is used to treat opioid dependence (addiction to opioid drugs). It contains Buprenorphine which prevents withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It may also provide pain relief by acting on specific receptors in the brain. This medicine may sometimes cause side effects such as dry mouth, vomiting, blurred vision, constipation, dizziness, tiredness and injection site reactions. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

BUPRENORPHINE-0.6MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About BUPRIGESIC 0.6MG INJECTION

BUPRIGESIC 0.6MG INJECTION belongs to a class of drugs called 'opioid analgesic' primarily used to treat opioid addiction (narcotics) like morphine, heroin, etc. In some cases, it is also used to treat, prevent and treat moderate to severe pain. Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behaviour and leads to an inability to control the use of a legal or illegal drug or medication.

BUPRIGESIC 0.6MG INJECTION contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

BUPRIGESIC 0.6MG INJECTION will be administered by a trained healthcare professional. Hence, do not self-administer. This medicine may cause certain side effects such as dry mouth, vomiting, blurred vision, constipation, dizziness, tiredness and injection site reactions. Most of these side effects of BUPRIGESIC 0.6MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

BUPRIGESIC 0.6MG INJECTION should be avoided if you are allergic to it. Do not use BUPRIGESIC 0.6MG INJECTION if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. This medicine is not recommended for children below 18 years of age. BUPRIGESIC 0.6MG INJECTION is a habit-forming drug, and there is a risk of dependence on BUPRIGESIC 0.6MG INJECTION. Hence, do not stop receiving BUPRIGESIC 0.6MG INJECTION without consulting a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feeling. BUPRIGESIC 0.6MG INJECTION may decrease fertility in men and women. Do not consume alcohol with BUPRIGESIC 0.6MG INJECTION as it may increase the risk of side effects. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease before starting treatment with BUPRIGESIC 0.6MG INJECTION.

Uses of BUPRIGESIC 0.6MG INJECTION

Treatment of Opioid (drug) addiction, Pain.

Directions for Use

• Your doctor will determine the dosage and timing of BUPRIGESIC 0.6MG INJECTION based on your medical condition.• BUPRIGESIC 0.6MG INJECTION is administered subcutaneously (under the skin) by a healthcare professional in a medical setting.• Do not self-administer it.

Medicinal Benefits

The BUPRIGESIC 0.6MG INJECTION contains Buprenorphine as a substitution (replacement) treatment in patients addicted to opioid drugs (heroin and morphine, etc.). It prevents or reduces the unpleasant withdrawal symptoms experienced when addicts stop using opioid drugs. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, BUPRIGESIC 0.6MG INJECTION has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses. 

How BUPRIGESIC 0.6MG INJECTION Works

BUPRIGESIC 0.6MG INJECTION contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Storage

Keep BUPRIGESIC 0.6MG INJECTION out of the sight and reach of children.

What if I have taken an overdose of BUPRIGESIC 0.6MG INJECTION

Overdose of BUPRIGESIC 0.6MG INJECTION may cause narrowing or widening of the pupils (black circles in the centre of the eye), slowed/shallow/difficulty breathing, extreme sleepiness or drowsiness, unable to respond or wake up, coma (loss of consciousness for a period of time), and slow heartbeat. Since BUPRIGESIC 0.6MG INJECTION is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any of these symptoms.

Drug Warnings

Please do not stop receiving BUPRIGESIC 0.6MG INJECTION suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to BUPRIGESIC 0.6MG INJECTION or any other medicines, please tell your doctor.  Do not use BUPRIGESIC 0.6MG INJECTION if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. BUPRIGESIC 0.6MG INJECTION is not recommended for children below 18 years of age.  Avoid consuming alcohol with BUPRIGESIC 0.6MG INJECTION as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. BUPRIGESIC 0.6MG INJECTION should be used with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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How does the drug interact with Buprigesic 0.6mg Injection:
Taking Ziprasidone with Buprigesic 0.6mg Injection can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Buprigesic 0.6mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
BuprenorphineAlvimopan
Critical
How does the drug interact with Buprigesic 0.6mg Injection:
Using alvimopan together with Buprigesic 0.6mg Injection can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Buprigesic 0.6mg Injection is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Buprigesic 0.6mg Injection:
Taking Buprigesic 0.6mg Injection with chlorpromazine can increase the risk of serious side effects.

How to manage the interaction:
Taking Buprigesic 0.6mg Injection with chlorpromazine can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
BuprenorphinePhensuximide
Severe
How does the drug interact with Buprigesic 0.6mg Injection:
Using Buprigesic 0.6mg Injection together with Phensuximide can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Phensuximide and Buprigesic 0.6mg Injection, but it can be taken if prescribed by a doctor. Doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Buprigesic 0.6mg Injection:
When Buprigesic 0.6mg Injection is used with lamotrigine, it may possibly lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of Buprigesic 0.6mg Injection alongside lamotrigine can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 0.6mg Injection:
Coadministration of Buprigesic 0.6mg Injection with Tizanidine may increase the risk of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Coadministration of Buprigesic 0.6mg Injection with Tizanidine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, dizziness, palpitations, or sweating, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 0.6mg Injection:
Using Buprigesic 0.6mg Injection together with Ethosuximide may cause central nervous system depression can lead to serious side effects (respiratory distress).

How to manage the interaction:
Concomitant administration of Buprigesic 0.6mg Injection alongside ethosuximide can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these drugs effect you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 0.6mg Injection:
Using Pregabalin together with Buprigesic 0.6mg Injection causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprigesic 0.6mg Injection and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 0.6mg Injection:
Using arsenic trioxide together with Buprigesic 0.6mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Arsenic trioxide with Buprigesic 0.6mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. If you experience an irregular heart rhythm, a heart condition, a condition called congenital long qt syndrome, problems with your heart's electrical system, severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Buprigesic 0.6mg Injection:
The combination of Buprigesic 0.6mg Injection and midazolam can result in central nervous system depression (slowing of the body's neurological functioning).

How to manage the interaction:
Concomitant administration of Buprigesic 0.6mg Injection along with Midazolam can result in an interaction. However, it can be taken if a doctor has advised it. If you experience any symptoms of breathing problems and unconsciousness, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as swimming or walking.
  • Drink plenty of water while on treatment with BUPRIGESIC 0.6MG INJECTION to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while receiving BUPRIGESIC 0.6MG INJECTION.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS
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Alcohol

Unsafe

BUPRIGESIC 0.6MG INJECTION may cause dizziness, drowsiness, blurred vision, or impaired thinking in some people. Alcohol consumption may even worsen these effects. Hence, do not consume alcohol while on treatment with this medicine.

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Pregnancy

Unsafe

BUPRIGESIC 0.6MG INJECTION is not recommended during pregnancy as it may cause life-threatening withdrawal symptoms in the newborn. Hence, inform your doctor before administering BUPRIGESIC 0.6MG INJECTION if you are pregnant or planning pregnancy. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it passes into breastmilk and may cause sleepiness and decreased heart rate in your infant. It is not recommended for use in breastfeeding. Hence, if you are breastfeeding, inform your doctor before receiving BUPRIGESIC 0.6MG INJECTION. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

BUPRIGESIC 0.6MG INJECTION may cause dizziness, blurred vision or drowsiness in some people. It is an offence to drive if BUPRIGESIC 0.6MG INJECTION affects you. Therefore, avoid driving if you feel drowsy, dizzy or experience vision problems after administration of BUPRIGESIC 0.6MG INJECTION.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving BUPRIGESIC 0.6MG INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving BUPRIGESIC 0.6MG INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

BUPRIGESIC 0.6MG INJECTION is not recommended for use in children below 18 years of age as the safety and effectiveness have not been established.

Have a query?

FAQs

BUPRIGESIC 0.6MG INJECTION is used to treat opioid addiction.

BUPRIGESIC 0.6MG INJECTION consists of Buprenorphine is an opioid partial agonist. It prevents withdrawal symptoms in patients who stop receiving opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

Yes, BUPRIGESIC 0.6MG INJECTION may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience any difficulty while receiving BUPRIGESIC 0.6MG INJECTION, do not stop administration suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Chronic use of opioids may cause reduced fertility (ability to have children) in females and males of reproductive potential. It is not known whether these effects on fertility are reversible. However, it is essential to talk to your doctor before starting treatment with BUPRIGESIC 0.6MG INJECTION if you think you may want to have a baby in the future.

No, you are not recommended to use BUPRIGESIC 0.6MG INJECTION with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with BUPRIGESIC 0.6MG INJECTION may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before receiving BUPRIGESIC 0.6MG INJECTION with other medicines.

Yes, BUPRIGESIC 0.6MG INJECTION may cause addiction, especially if used for a prolonged time. Therefore, BUPRIGESIC 0.6MG INJECTION should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. BUPRIGESIC 0.6MG INJECTION should be administered only as advised by a doctor as overuse, or misuse of BUPRIGESIC 0.6MG INJECTION can lead to overdose or death.

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - BUP0006

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