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  3. Budamate 400 Transhaler

Budamate 400 Transhaler, Pack of 1 INHALER
Budamate 400 Transhaler, Pack of 1 INHALER
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Budamate 400 Transhaler is used to treat asthma and chronic obstructive pulmonary disease (COPD). It contains Budesonide and Formoterol, which work by reducing the swelling and relaxing air passages in the lungs, making it easier to breathe. Some people may experience side effects such as fungal infection in the mouth, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, back pain, increased heart rate, and trembling. Before starting this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

BUDESONIDE-400MCG + FORMOTEROL-6MCG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Budamate 400 Transhaler

Budamate 400 Transhaler is used to treat asthma and chronic obstructive pulmonary diseases (COPD). It helps prevent and treat difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness associated with asthma and COPD.

Budamate 400 Transhaler contains Budesonide and Formoterol. Budesonide reduces the swelling of the airways, and Formoterol works by relaxing and opening air passages in the lungs, making it easier to breathe.

Some people may experience fungal infection in the mouth, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, back pain, increased heart rate, and trembling. If the side effects persist or worsen, please consult your doctor.

Do not take Budamate 400 Transhaler if you are allergic to any of its components. If you are pregnant or breastfeeding, consult your doctor before using Budamate 400 Transhaler. Keep your doctor informed about your medications and medical conditions to prevent any potential interactions.

Uses of Budamate 400 Transhaler

Budamate 400 Transhaler is used in the treatment of Asthma and Chronic Obstructive Pulmonary Disease (COPD). The detailed uses of Budamate 400 Transhaler are as follows:

  • Asthma management: Budamate 400 Transhaler is widely prescribed for asthma patients to reduce inflammation and prevent asthma attacks. It works by relaxing airway muscles, easing breathing and providing effective relief.
  • COPD treatment: Budamate 400 Transhaler is highly effective in managing chronic obstructive pulmonary disease (COPD), a progressive lung condition. It helps alleviate symptoms like breathlessness and wheezing, ensuring better respiratory function.
  • Maintenance therapy: It is used as regular maintenance therapy and as needed in response to symptoms.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Hold Budamate 400 Transhaler with the mouthpiece downwards. Put the mouthpiece between your teeth and seal the lips around it. Then, press down on the inhaler once to release the medication. Breathe in slowly and hold your breath for 5 to 10 seconds. Breathe out slowly. Repeat the process until you have inhaled the number of puffs prescribed by the doctor.
  • Rinse your mouth with water and spit it out after using Budamate 400 Transhaler to avoid fungal infections in the mouth and throat.

Medicinal Benefits

  • Budamate 400 Transhaler is a combination inhalation therapy that contains Budesonide (an inhaled corticosteroid) and Formoterol (a long-acting beta-2 adrenergic agonist).
  • This combination offers both anti-inflammatory and bronchodilator actions, providing comprehensive control over respiratory conditions such as Asthma and Chronic Obstructive Pulmonary Disease (COPD).
  • Budesonide reduces airway inflammation, while Formoterol helps to relax the airway muscles, leading to improved airflow and reduced breathlessness.
  • Budamate 400 Transhaler is used as a regular maintenance therapy for individuals with asthma where the use of inhaled corticosteroids and long-acting beta-agonists (LABA) is appropriate.
  • It reduces airway inflammation and prevents bronchospasm, thereby minimising the frequency and severity of asthma attacks.
  • Helps maintain long-term asthma control, improves lung function, and enhances quality of life.
  • Budamate 400 Transhaler is also indicated for the regular treatment of moderate to severe COPD in patients who experience frequent symptoms and have a history of exacerbation.
  • Budamate 400 Transhaler decreases the rate and severity of COPD exacerbations and maintains day-to-day function.

How Budamate 400 Transhaler Works

Budamate 400 Transhaler contains budesonide (corticosteroid) and formoterol (bronchodilator). Budesonide prevents the release of certain chemicals responsible for causing inflammatory reactions. Formoterol fumarate relaxes and widens the respiratory airway muscles, making it easier to breathe. Together, Budamate 400 Transhaler helps treat asthma and COPD.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Budamate 400 Transhaler

Do not use Budamate 400 Transhaler in more doses or more often than prescribed. Symptoms of overdose include tremor, headache, and tachycardia (fast heartbeat). If you experience any of these symptoms or suspect an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not use Budamate 400 Transhaler if you are allergic to any of its components.
  • If you are pregnant or breastfeeding, it is advised to inform your doctor before using Budamate 400 Transhaler.
  • Budamate 400 Transhaler is not recommended for children below 6 years of age.
  • If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning that lasts longer than usual, please consult a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment.
  • Regular monitoring of potassium levels is recommended while taking Budamate 400 Transhaler, as it may cause low potassium levels in the blood.
  • Avoid contact with people who have infections or who are sick, as Budamate 400 Transhaler may weaken the immune system, causing infections to be easily contracted.
  • If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver or adrenal gland problems, inform your doctor before using Budamate 400 Transhaler.

Drug-Drug Interactions

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BudesonideMifepristone
Critical
BudesonideRibociclib
Critical

Drug-Drug Interactions

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BudesonideMifepristone
Critical
How does the drug interact with Budamate 400 Transhaler:
Using mifepristone together with Budamate 400 Transhaler may significantly reduce the effects of Budamate 400 Transhaler.

How to manage the interaction:
Taking Budamate 400 Transhaler with Mifepristone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
BudesonideRibociclib
Critical
How does the drug interact with Budamate 400 Transhaler:
Coadministration of Budamate 400 Transhaler and Ribociclib may increase the absorption of the medication from Budamate 400 Transhaler into the blood stream.

How to manage the interaction:
Taking Ribociclib with Budamate 400 Transhaler can cause an interaction, consult a doctor before taking it. Consult a doctor if experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not stop using any medications without talking to a doctor.
FormoterolEpinephrine
Severe
How does the drug interact with Budamate 400 Transhaler:
Using epinephrine together with Budamate 400 Transhaler may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Budamate 400 Transhaler and Epinephrine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolNadolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Taking nadolol with Budamate 400 Transhaler together could decrease the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Budamate 400 Transhaler and Nadolol, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolPropranolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Coadministration of propranolol with Budamate 400 Transhaler can reduce the effects of both medications.

How to manage the interaction:
Although taking propranolol and Budamate 400 Transhaler together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolLevobunolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Using Budamate 400 Transhaler together with levobunolol can reduce the effects of both medications.

How to manage the interaction:
Taking Budamate 400 Transhaler with Levobunolol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolCarteolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Taking carteolol with Budamate 400 Transhaler can reduce the effects of both drugs.

How to manage the interaction:
Although there is an interaction between Carteolol and Budamate 400 Transhaler, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FormoterolMetipranolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Using Budamate 400 Transhaler together with metipranolol can reduce the effects of both medications.

How to manage the interaction:
Although there is an interaction between Budamate 400 Transhaler and metipranolol, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolPenbutolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Using Budamate 400 Transhaler together with penbutolol can reduce the effect of both medications.

How to manage the interaction:
There may be a possibility of interaction between Penbutolol and Budamate 400 Transhaler, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolRibociclib
Severe
How does the drug interact with Budamate 400 Transhaler:
Taking ribociclib together with Budamate 400 Transhaler can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Budamate 400 Transhaler with Ribociclib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, contact your doctor right away. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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BUDESONIDE-400MCG+FORMOTEROL-6MCGFruit juices, Fruits
Moderate

Drug-Food Interactions

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BUDESONIDE-400MCG+FORMOTEROL-6MCGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Budamate 400 Transhaler levels in your body can grow due to grapefruit, which will result in more side effects. While using Budamate 400 Transhaler, you must stay away from consuming grapefruits and grapefruit juice. In case of any unusual side effects, consult a doctor. Do not discontinue any medication without consulting a doctor.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice as they may worsen asthma symptoms.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of the Budamate 400 Transhaler and irritate the lungs, worsening breathing problems.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Budamate 400 Transhaler Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

The interaction of Budamate 400 Transhaler with alcohol is unknown. Please consult a doctor before consuming alcohol with Budamate 400 Transhaler.

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Pregnancy

Consult your doctor

The safety of Budamate 400 Transhaler in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Budamate 400 Transhaler is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

bannner image

Driving

Safe if prescribed

Budamate 400 Transhaler usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Budamate 400 Transhaler with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Budamate 400 Transhaler in patients with Kidney problems, please consult a doctor.

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Children

Consult your doctor

Budamate 400 Transhaler is not recommended for children below 6 years as the safety and effectiveness were not established. However, please consult a doctor before giving Budamate 400 Transhaler to children.

Have a query?

FAQs

Budamate 400 Transhaler is used to treat asthma and chronic obstructive pulmonary disease (COPD).

Yes, Budamate 400 Transhaler may cause fungal infection in the mouth (oral thrush) as a common side effect. It is not necessary for everyone taking Budamate 400 Transhaler to experience this side effect. However, to avoid such side effects, brush your teeth or rinse your mouth with water after using Budamate 400 Transhaler every time.

Budamate 400 Transhaler should be used with caution in osteoporosis (low bone density resulting in weak and brittle bones) patients, as it may worsen the condition. Therefore, inform your doctor if you have osteoporosis before taking Budamate 400 Transhaler so that the dose may be adjusted or an alternate medicine may be prescribed.

No, you are not recommended to take ketoconazole or other antifungal drugs such as itraconazole, posaconazole and voriconazole with Budamate 400 Transhaler as co-administration of these medicines may increase the absorption of Budamate 400 Transhaler into the bloodstream and increase the risk of adverse effects such as high blood pressure, weight gain, depression, muscle weakness, swelling, acne, skin thinning, cataracts, excessive growth of facial or body hair, stretch marks, high blood glucose levels, menstrual irregularities, loss of bone density, easy bruising and abnormal distribution of body fat, especially in the waist, back, neck and face, neck. However, please consult a doctor before using other medicines with Budamate 400 Transhaler.

You are not recommended to take more than the prescribed dose of Budamate 400 Transhaler as it may cause adverse effects such as a fast heartbeat, trembling or headache. However, if you experience any of these symptoms while taking Budamate 400 Transhaler, please consult a doctor immediately.

You are not recommended to stop taking Budamate 400 Transhaler without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Budamate 400 Transhaler for as long as your doctor has prescribed it, and if you experience any difficulty while taking Budamate 400 Transhaler, please consult your doctor.

Budamate 400 Transhaler does not relieve a sudden asthma attack. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

Throat irritation or pain, oral thrush (fungal infection), respiratory tract infections, low potassium level and sinusitis (sinus inflammation) are some of the common side effects of Budamate 400 Transhaler, which might occur in some patients.

In rare cases, Budamate 400 Transhaler may cause a low potassium level. So if you experience tiredness, muscle cramps, weakness, abnormal heart rhythms (arrhythmias) and constipation, contact a doctor for advice.

People with heart problems (including high blood pressure, chest pain, fast heartbeat, fits (seizures), thyroid problems, diabetes, immune system problems, weak bones or osteoporosis, eye problems (glaucoma, cataracts) and liver problems should consult a doctor before using Budamate 400 Transhaler.

Yes, Budamate 400 Transhaler is a combination of two drugs: Budesonide (a corticosteroid) and Formoterol (LABA—long-acting beta-agonists or bronchodilators).

No, taking more than the prescribed dose may not be more effective; it may raise the possibility of experiencing severe adverse reactions.

Rinse your mouth with water after each dose to help prevent infection. Do not swallow the water after rinsing.

Before taking the Budamate 400 Transhaler, let your doctor know about all your medical conditions, sensitivities, and all the medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

You may start to feel better after a couple of weeks. But it can take a month or more to work fully.

It's possible that your immune system is not strong enough to receive a live vaccine while you're taking Budamate 400 Transhaler. If you need vaccinations, inform the healthcare professional that you're taking Budamate 400 Transhaler.

It depends on your health condition. As directed by your physician, you will need to use it for longer to keep symptoms under control.

The safety of Budamate 400 Transhaler in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

Store it at room temperature and away from sunlight, excess heat and moisture (not in the bathroom). Please dispose of the inhaler three months after you remove it from the foil overwrap or when the dose indicator reads 0), whichever comes first.

Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. Symptoms include wheezing (a whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - BUD0033

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 1, 2025 | 6:20 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021929s013lbl.pdf
  2. https://www.drugs.com/cdi/budesonide-and-formoterol.html

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