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compositionComposition:BRIVARACETAM-10MG
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Prescription Medicine
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Brivapride 10 Injection 5 ml is used to treat Partial-onset seizures. It contains Brivaracetam, which reduces the electrical impulses and decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures. Common side effects include somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea, and vomiting. Inform your doctor if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BRIVARACETAM-10MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Brivapride 10 Injection 5 ml

Brivapride 10 Injection 5 ml is a prescription intravenous medicine used to treat partial-onset seizures in adults and children. In many countries, the intravenous formulation is approved for patients 4 years of age and older when oral treatment is temporarily not feasible. It helps control abnormal electrical activity in the brain and is commonly used when oral levetiracetam cannot be taken temporarily, such as during hospitalisation, surgery, or when swallowing is difficult. This medicine helps maintain seizure control until oral treatment can be resumed.

To achieve the best results, you should receive Brivapride 10 Injection 5 ml exactly as prescribed by your doctor, usually twice daily at evenly spaced intervals. Since it is administered directly into a vein, food does not affect its absorption. Maintaining a regular sleep schedule, managing stress, and taking your seizure medicines consistently can further improve seizure control.

While receiving this medicine, you may experience mild side effects such as drowsiness, dizziness, headache, or nausea. However, seek immediate medical attention if you develop severe mood changes, depression, suicidal thoughts, severe allergic reactions, or difficulty breathing.

Before receiving this medicine, tell your doctor if you have kidney disease, liver disease, depression, or any other mental health condition. Do not receive this medicine if you have previously experienced a severe allergic reaction (hypersensitivity) to Brivapride 10 Injection 5 ml or any of its ingredients (excipients). Tell your doctor if you have ever had an allergic reaction to this medicine. 

This medicine may interact with alcohol and other medicines that cause drowsiness, increasing the risk of excessive sleepiness and impaired alertness. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor before starting treatment to ensure this medicine is appropriate for you.

Uses of Brivapride 10 Injection 5 ml

Your doctor may prescribe Brivapride 10 Injection 5 ml to treat the following condition:

  • Partial-onset seizures: Helps reduce the frequency and severity of focal seizures by controlling abnormal electrical activity in the brain.

Key Benefits

Brivapride 10 Injection 5 ml helps provide reliable seizure control when oral medication cannot be taken. Because it is administered directly into a vein, it maintains therapeutic drug levels quickly, helping prevent breakthrough seizures during hospitalisation or temporary inability to swallow medicines.

  • Maintains seizure control: Helps prevent partial-onset seizures when oral treatment is temporarily not possible.
  • Rapid and reliable treatment: Direct intravenous administration allows the medicine to begin working quickly without depending on absorption through the digestive tract.
  • Supports uninterrupted epilepsy management: Ensures continuous seizure treatment during surgery, severe illness, or recovery until oral medication can be restarted.
  • Helps reduce seizure-related complications: Consistent seizure control lowers the risk of injury, prolonged seizures, and disruption to daily activities.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Brivapride 10 Injection 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Brivapride 10 Injection 5 ml Works

Brivapride 10 Injection 5 ml contains brivaracetam, belongs to a class of medicines called antiepileptic drugs (AEDs). It works by binding to a protein in the brain called synaptic vesicle protein 2A (SV2A), which helps regulate communication between nerve cells. By modifying the release of chemical messengers between neurons, Brivapride 10 Injection 5 ml stabilises abnormal electrical activity in the brain and reduces the likelihood of uncontrolled nerve firing that leads to seizures. This helps prevent seizures while allowing normal brain function to continue.
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects, such as dizziness and sleepiness.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Inform your doctor before receiving Brivapride 10 Injection 5 ml if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There has been no significant research on using Brivapride 10 Injection 5 ml in breastfeeding/nursing moms. So, let your doctor know if you are a nursing mother before taking Brivapride 10 Injection 5 ml; your doctor will decide whether Brivapride 10 Injection 5 ml can be taken by breastfeeding mothers.

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Driving

Unsafe

Brivapride 10 Injection 5 ml may cause somnolence (excess sleepiness) and fatigue (feeling overtired). It impacts your daily activities; hence, avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Dose adjustments are recommended for patients with hepatic impairment. So inform your doctor before receiving Brivapride 10 Injection 5 ml if you have a history of liver impairments.

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Kidney

Caution

Brivapride 10 Injection 5 ml is recommended not to be used in end-stage renal disease patients undergoing dialysis. Inform your doctor before receiving Brivapride 10 Injection 5 ml if you have a history of kidney diseases/conditions.

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Children

Safe if prescribed

Brivapride 10 Injection 5 ml is safe for use in children if prescribed by the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Heart

Safe if prescribed

Brivapride 10 Injection 5 ml is generally considered safe for heart patients. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Brivapride 10 Injection 5 ml is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Brivapride 10 Injection 5 ml

Because this medicine is administered under medical supervision, overdose is uncommon. However, if an overdose is suspected, seek immediate medical attention. Symptoms may include extreme drowsiness, confusion, agitation, slowed breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Maintain a regular sleep schedule: Sleep deprivation can increase the risk of seizures.
  • Avoid alcohol: Alcohol may reduce seizure control and increase dizziness and drowsiness.
  • Take seizure medicines consistently: Never skip doses or stop treatment without consulting your doctor.
  • Manage stress: Practice relaxation techniques such as meditation, yoga, or deep breathing, as stress can trigger seizures.
  • Keep a seizure diary: Record seizure episodes, possible triggers, and medication adherence to help your doctor optimize treatment.
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How Soon It Starts Working

The time required for Brivapride 10 Injection 5 ml to start to work: The exact onset time of Brivapride 10 Injection 5 ml has not been clinically established.

The time for which the effects of Brivapride 10 Injection 5 ml last: The duration of Brivapride 10 Injection 5 ml’s effect is clinically not established.

What if you forget to take Brivapride 10 Injection 5 ml

Because this medicine is usually administered by a healthcare professional, missed doses are uncommon. If you miss an appointment for your injection, contact your healthcare provider as soon as possible to arrange another appointment. Do not receive a double dose to make up for a missed dose.

Storage

• Store Brivapride 10 Injection 5 ml at controlled room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Inspect the solution: Do not use the injection if it appears cloudy, discoloured, or contains visible particles.
  • Do not stop treatment suddenly: Abrupt discontinuation may increase the risk of seizures or status epilepticus.
  • Monitor mood changes: Inform your doctor immediately if you experience depression, anxiety, aggression, or suicidal thoughts.
  • Avoid driving until you know its effects: This medicine may cause dizziness or drowsiness, especially when treatment is started.
  • Keep follow-up appointments: Regular monitoring helps your doctor assess seizure control and determine when to transition back to oral medication.

verifiedApollotooltip
  • Sedatives, opioid pain medicines, sleeping pills, or anti-anxiety medicines: May increase drowsiness, dizziness, and impaired alertness.
  • Methotrexate: No clinically significant interaction has been established with Brivapride 10 Injection 5 ml. Always inform your doctor about all medicines you are taking so they can assess potential interactions.
  • Other antiepileptic medicines: Although significant interactions are uncommon, dose adjustments may occasionally be required based on clinical response.

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verifiedApollotooltip
  • Alcohol: Avoid alcohol during treatment, as it may increase drowsiness, impair coordination, and reduce seizure control.

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Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

[ANTICONVULSANT]

FAQs

Brivapride 10 Injection 5 ml is used to treat Partial-onset seizures.
Brivapride 10 Injection 5 ml contains Brivaracetam, an antiepileptic, which works by suppressing the abnormal activity in the brain and prevents the spread of electrical signals that cause seizures.
To treat your condition effectually, continue taking Brivapride 10 Injection 5 ml for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Brivapride 10 Injection 5 ml; your doctor will gradually reduce the dose to avoid precipitating seizures.
Brivapride 10 Injection 5 ml may cause suicidal thoughts such as killing or harming yourself. People taking Brivapride 10 Injection 5 ml should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.
Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.
Brivapride 10 Injection 5 ml intravenous injection is typically administered by a trained healthcare professional in a hospital or clinical setting. Home administration is not routine and should only occur if specifically recommended and supervised by your healthcare team in accordance with local medical practice.
Mild drowsiness is a common side effect when starting Brivapride 10 Injection 5 ml. Avoid driving or performing tasks that require alertness until you know how the medicine affects you. Talk to your doctor if the sleepiness does not improve.
Because it is injected directly into a vein, Brivapride 10 Injection 5 ml enters your bloodstream immediately and starts working quickly to help stabilise brain activity. Talk to your doctor for more details about your specific response.
Seizure control is vital during pregnancy, but Brivapride 10 Injection 5 ml should only be used if the potential benefits outweigh the risks. If you are pregnant or planning to become pregnant, talk to your doctor immediately.
Yes, some people using Brivapride 10 Injection 5 ml may experience mood changes, irritability, or depression. If you or your family notice any unusual behavioural changes, contact your doctor right away.
Yes, Brivapride 10 Injection 5 ml can interact with certain other seizure drugs. Your doctor will review your complete medication list to ensure all your treatments work safely together. Talk to your doctor or pharmacist.
Do not use the injection if the liquid is cloudy, discoloured, or contains any particles. Discard the vial safely and use a new one. Talk to your pharmacist if you need advice on replacement vials.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - BRI0631
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