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compositionComposition:IBANDRONIC ACID-6MG
prescription
Prescription Medicine
info
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Bondronat 6 mg Injection 6 ml contains ibandronic acid mainly used in the treatment of post-menopausal osteoporosis. It belongs to the class of bisphosphonates which mainly works by suppressing the activity of osteoclasts and thereby makes the bone stronger. Sometimes, it may cause side effects like joint pain, back pain, headache, injection site reactions, and abdominal pain.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IBANDRONIC ACID-6MG

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bondronat 6 mg Injection 6 ml

Bondronat 6 mg Injection 6 ml is a prescribed injection used to treat osteoporosis in women after menopause. Its primary medical purpose is to help increase bone mineral density, making your bones thicker and less likely to break. By strengthening the overall bone structure, it helps protect you from painful fractures, especially in the spine.

Your healthcare provider will schedule your injections at regular intervals to ensure consistent protection for your bones. It is highly important to attend every scheduled appointment to keep your treatment working effectively. Because this medicine is injected directly, food intake does not interfere with how it works, though maintaining a balanced lifestyle with healthy habits remains essential for the best results.

While this medicine is highly effective, some people may experience mild, temporary side effects such as flu-like symptoms, headaches, or back pain. However, you must contact your doctor immediately if you experience serious issues like severe pain in your jaw, unusual hip or thigh pain, or signs of a severe allergic reaction.

Before starting this treatment, always talk to your doctor if you have kidney disease, low blood calcium levels, or upcoming major dental work. Do not take this if you have untreated low blood calcium levels or severe kidney damage. This medicine is also not suitable for pregnant or breastfeeding women.

It is important to inform your doctor about all other medicines you take, as some drugs can harm your kidneys when combined with this treatment. Lifestyle habits like smoking and excessive alcohol consumption should be avoided, as they can weaken your bones. If you are an older adult, discuss the specific risks and benefits with your healthcare team to ensure this treatment is safe for you.

Uses of Bondronat 6 mg Injection 6 ml

Bondronat 6 mg Injection 6 ml is used to treat osteoporosis in women after menopause. The detailed uses of Bondronat 6 mg Injection 6 ml are as follows:

  • Postmenopausal osteoporosis: Bondronat 6 mg Injection 6 ml helps slow down the natural process of bone loss, increasing bone thickness and significantly reducing the risk of spinal fractures in women after menopause.
  • Preservation of bone mass: It helps protect and maintain skeletal strength in individuals who are at a very high risk of bone thinning and fractures.

Key Benefits

Bondronat 6 mg Injection 6 ml helps strengthen bones and reduce the risk of fractures by improving bone density. With regular use as prescribed, it provides long-term protection for your skeletal system and supports an active, independent lifestyle.

  • Strengthens Bones: By increasing bone density, this medicine helps strengthen bones, reduce the risk of fractures, and support long-term skeletal health.
  • Supports Mobility and Independence: Stronger bones help maintain better posture, improve physical stability, and allow you to perform daily activities with greater confidence and comfort.
  • Convenient Long-Term Treatment: Because this medicine is administered as an injection at scheduled intervals, it offers a convenient alternative to frequent oral bone medications and supports consistent osteoporosis management.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Bondronat 6 mg Injection 6 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Bondronat 6 mg Injection 6 ml Works

Our bones are living tissues that constantly break down and rebuild. In osteoporosis, the cells that break down bone work faster than the cells that build it, leading to weak, porous bones. Bondronat 6 mg Injection 6 ml contains ibandronic acid, which belongs to a class of medicines that target and temporarily slow down these bone-clearing cells. By reducing the rate at which bone is broken down, the medicine allows your body's natural bone-building processes to catch up. Over time, this rebalances the bone cycle, resulting in increased bone mineral density and a much stronger skeletal structure that is highly resistant to fractures.
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Alcohol

Caution

It is not known if alcohol affects Bondronat 6 mg Injection 6 ml. Please consult your doctor.

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Pregnancy

Caution

Bondronat 6 mg Injection 6 ml is indicated for use in postmenopausal women. Consult your doctor if you are pregnant. Your doctor will prescribe Bondronat 6 mg Injection 6 ml only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Bondronat 6 mg Injection 6 ml passes into breast milk. Inform your doctor before taking this medicine if you are breastfeeding.

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Driving

Safe if prescribed

Bondronat 6 mg Injection 6 ml has no or negligible influence on the ability to drive.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Bondronat 6 mg Injection 6 ml is not recommended for people with severe renal impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Bondronat 6 mg Injection 6 ml is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Bondronat 6 mg Injection 6 ml should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Bondronat 6 mg Injection 6 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Bondronat 6 mg Injection 6 ml to geriatric patients. Your doctor will prescribe Bondronat 6 mg Injection 6 ml if the benefits outweigh the risks.

What if I have taken an overdose of Bondronat 6 mg Injection 6 ml

Because this medication is administered under strict clinical supervision by a healthcare professional, an overdose is highly unlikely. However, if you suspect an error or experience severe, unusual symptoms, seek immediate medical attention.

Diet & Lifestyle Advise

  • Optimise calcium and vitamin D intake: Your body requires these essential nutrients to build and maintain strong bones. Talk to your doctor or pharmacist about whether you need daily supplements.
  • Perform weight-bearing exercises: Activities like walking, light jogging, or using resistance bands help stimulate bone strength and improve balance to prevent falls.
  • Avoid smoking: Smoking speeds up bone loss and can reduce the overall benefits of your bone-strengthening treatments.
  • Limit alcohol consumption: High alcohol intake can interfere with bone growth and increase your risk of slipping or falling.
  • Maintain excellent oral hygiene: Brush and floss daily, and visit your dentist regularly, as good oral health minimises the rare risk of jaw bone complications.
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How Soon It Starts Working

The time required for Bondronat 6 mg Injection 6 ml to start to work: The onset time of Bondronat 6 mg Injection 6 ml has not been clinically established. The time for which the effects of Bondronat 6 mg Injection 6 ml last: The duration of Bondronat 6 mg Injection 6 ml’s effect is clinically not established.

What if you forget to take Bondronat 6 mg Injection 6 ml

If you miss an appointment for your injection, contact your doctor or healthcare clinic as soon as possible to reschedule. Do not attempt to receive a double dose to make up for a missed appointment.

Storage

•This medicine must be stored at a controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F).
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Ensure your healthcare provider inspects the injection vial before use; the liquid must be completely clear and colourless, without any floating particles.
  • Inform your dentist or oral surgeon that you are receiving Bondronat 6 mg Injection 6 ml injections before undergoing any dental procedures, especially tooth extractions.
  • Keep all your scheduled blood test appointments so your doctor can regularly check your kidney function and blood calcium levels.
  • Stay well-hydrated by drinking plenty of water on the day of your scheduled injection to help protect your kidneys.
  • Promptly report any new or unusual pain in your hip, thigh, or groin to your healthcare provider, as this requires immediate evaluation.

Drug-Drug Interactions

verifiedApollotooltip

  • Aminoglycoside antibiotics: Combining these medications with Bondronat 6 mg Injection 6 ml can cause your blood calcium levels to drop dangerously low.
  • Kidney-harming medicines: Taking certain strong pain relievers (like NSAIDs) or specific antibiotics alongside this injection can increase your risk of kidney damage.
Ibandronic acidSirolimus
Severe
Ibandronic acidTenofovir alafenamide
Severe

Drug-Drug Interactions

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Ibandronic acidSirolimus
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Sirolimus and Bondronat 6 mg Injection 6 ml may cause an increase in the risk or severity of kidney damage.

How to manage the interaction:
Although taking Bondronat 6 mg Injection 6 ml and Sirolimus together may lead to an interaction, it can be taken if a doctor has suggested it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medication without consulting a doctor.
Ibandronic acidTenofovir alafenamide
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Tenofovir alafenamide with Bondronat 6 mg Injection 6 ml can increase the risk of kidney damage.

How to manage the interaction:
Taking Bondronat 6 mg Injection 6 ml with Tenofovir alafenamide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medications without consulting a doctor.
Ibandronic acidTacrolimus
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Taking Tacrolimus and Bondronat 6 mg Injection 6 ml together may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tacrolimus and Bondronat 6 mg Injection 6 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Ibandronic acidCidofovir
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Cidofovir with Bondronat 6 mg Injection 6 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Bondronat 6 mg Injection 6 ml and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Ibandronic acidIohexol
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Iohexol with Bondronat 6 mg Injection 6 ml may increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Bondronat 6 mg Injection 6 ml and Iohexol, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Ibandronic acidHuman immunoglobulin
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Human immunoglobulin with Bondronat 6 mg Injection 6 ml may raise the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Human immunoglobulin and Bondronat 6 mg Injection 6 ml, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Ibandronic acidDeferasirox
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Deferasirox with Bondronat 6 mg Injection 6 ml (oral form) may raise your chance of experiencing gastrointestinal (stomach & intestine) bleeding and ulcers.

How to manage the interaction:
Co-administration of Bondronat 6 mg Injection 6 ml with Deferasirox can result in an interaction, but it can be taken if a doctor has advised it. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's essential to consult a doctor. Do not stop using any medications without a doctor's advice.
Ibandronic acidMetrizamide
Severe
How does the drug interact with Bondronat 6 mg Injection 6 ml:
Co-administration of Metrizamide with Bondronat 6 mg Injection 6 ml may increase the risk or severity of kidney damage

How to manage the interaction:
Taking Bondronat 6 mg Injection 6 ml with Metrizamide together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Bondronat 6 mg Injection 6 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BONE ENHANCERS]

FAQs

Bondronat 6 mg Injection 6 ml belongs to the group of medications called "bisphosphonates" used to prevent post-menopausal osteoporosis.
Bondronat 6 mg Injection 6 ml suppresses the activity of osteoclasts and makes the bone stronger. It increases bone mass and helps reduce the chance of having a fracture.
Bondronat 6 mg Injection 6 ml may cause osteonecrosis (bone damage) of the jaw. A full dental check-up is advised before starting Bondronat 6 mg Injection 6 ml. Consult your doctor immediately if you experience symptoms such as pain, swelling, redness of the gums, numbness or heaviness in the jaw, and loose teeth. If you are undergoing any dental work, inform the doctor that you are taking Bondronat 6 mg Injection 6 ml.
Bondronat 6 mg Injection 6 ml may cause unusual fractures of the thigh bone. Consult your doctor if you experience unusual pain in the hip, thigh or groin.
Bondronat 6 mg Injection 6 ml may lower the calcium levels in the blood. Call your doctor immediately if you notice symptoms such as spasms, twitches, or cramps in the muscle, numbness, or tingling sensation in the fingers, toes or around the mouth.
Bondronat 6 mg Injection 6 ml may cause flu-like symptoms such as fever, chills, fatigue, bone, joint, or muscle pain within 3 days after receiving Bondronat 6 mg Injection 6 ml. They usually get better within 24-48 hours. However, if the condition persists or worsens, consult a doctor.
Your doctor will establish a personalised injection schedule that is right for your bone density needs. Talk to your doctor to understand your specific treatment plan.
If you have severe kidney disease, this medicine may not be safe for you. Your healthcare provider will perform a blood test to check your kidney function before administering each dose. Talk to your doctor if you have concerns.
No, you do not need to fast. Because this medicine is injected directly into a vein, food and drinks do not interfere with how it is absorbed by your body. Talk to your doctor or pharmacist for more details.
Mild, flu-like symptoms are common after the first injection and usually go away on their own within a few days. You can consult your pharmacist about safe over-the-counter remedies to help you feel better. Talk to your doctor if the symptoms do not improve.
Yes, your doctor will likely advise you to take daily calcium and vitamin D supplements to provide the raw materials your body needs to rebuild your bones. Talk to your doctor to get the correct daily dosage recommendation.
No, this medicine is not recommended for use during pregnancy or while breastfeeding, as it may harm the developing baby. If you suspect you are pregnant, talk to your doctor immediately.

Disclaimer

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Reference

  1. U.S. Food and Drug Administration (FDA). 021858S020Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. DailyMed Database. Lookup.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Ibandronicacid(Cb) - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Ibandronate Oral Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Ibandronic acid. 2011. [Accessed on 02 Apr. 2019]Check here
  6. Ibandronic acid. 2003. [Accessed on 02 Apr. 2019]Check here
  7. Ibandronate Sodium Tablets [Prescribing Information]. 2022. [Accessed on 05 Jul. 2023]Check here

Country of origin

India

Manufacturer/Marketer address

Bayer Ag, Mã¼Llerstr. 178, 13353 Berlin
Other Info - BON0001
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