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  3. Bizo AM 5mg/2.5mg Tablet

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Bizo AM 5mg/2.5mg Tablet, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bizo AM 5mg/2.5mg Tablet is used to treat high blood pressure. It contains Amlodipine and Bisoprolol, which act by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future. It may cause common side effects, such as headaches, fatigue, and swollen ankles. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

AMLODIPINE-5MG + BISOPROLOL-2.5MG

Manufacturer/Marketer :

Spectra Therapeutics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Bizo AM 5mg/2.5mg Tablet

Bizo AM 5mg/2.5mg Tablet is used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Bizo AM 5mg/2.5mg Tablet contains Amlodipine and Bisoprolol. Amlodipine reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax our blood vessels by blocking the action of certain natural substances in our bodies.

You may have common side effects like headaches, feeling exhausted, and swollen ankles, which usually resolve after some time. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor.

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Please inform your doctor if you have had an allergic reaction to Bizo AM 5mg/2.5mg Tablet, are pregnant or planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, diabetes, a heart valve problem or a heart attack.

Uses of Bizo AM 5mg/2.5mg Tablet

Bizo AM 5mg/2.5mg Tablet is used in the treatment of High blood pressure (hypertension). The detailed uses of Bizo AM 5mg/2.5mg Tablet are as follows:

  • Hypertension Treatment: Bizo AM 5mg/2.5mg Tablet is used to treat high blood pressure by relaxing blood vessels and reducing heart rate.
  • Cardiovascular Protection: Bizo AM 5mg/2.5mg Tablet helps to prevent strokes and heart attacks, reduces the risk of heart failure, and lowers cardiovascular complications.

Have a query?

Directions for Use

  • Bizo AM 5mg/2.5mg Tablet can be taken with or without food, but taking it with food may help reduce stomach upset.
  • It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
  • Swallow Bizo AM 5mg/2.5mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Bizo AM 5mg/2.5mg Tablet is a combination of two medicines: Amlodipine and Bisoprolol, which together help in lowering raised blood pressure effectively.
  • Amlodipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. 
  • Bisoprolol (beta blocker) helps relax our blood vessels by blocking the action of certain natural substances in the body.
  • This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
  • This medication must be taken regularly to be effective.

How Bizo AM 5mg/2.5mg Tablet Works

Bizo AM 5mg/2.5mg Tablet contains Amlodipine (calcium channel blocker) and Bisoprolol (beta blocker). Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax our blood vessels by blocking the action of certain natural substances in our bodies. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medication must be taken regularly to be effective.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Bizo AM 5mg/2.5mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Bizo AM 5mg/2.5mg Tablet

Do not take more than the prescribed dose of Bizo AM 5mg/2.5mg Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Don't stop taking Bizo AM 5mg/2.5mg Tablet without talking to your doctor first.
  • Stopping Bizo AM 5mg/2.5mg Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack.
  • Your doctor will lower your dose gradually over a period of time to help prevent these symptoms.
  • You should not use Bizo AM 5mg/2.5mg Tablet if you have a very slow heartbeat, asthma, a serious heart condition (sick sinus syndrome), or any heart blockage.
  • It should not be given to children under 12 years of age.
  • Before taking Bizo AM 5mg/2.5mg Tablet you should tell your doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycaemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipinePrimidone
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Using Bizo AM 5mg/2.5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Bizo AM 5mg/2.5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Using Bizo AM 5mg/2.5mg Tablet and primidone together may lower Bizo AM 5mg/2.5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Bizo AM 5mg/2.5mg Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCeritinib
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Coadministration of Ceritinib together with Bizo AM 5mg/2.5mg Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Bizo AM 5mg/2.5mg Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Using a combination of Bizo AM 5mg/2.5mg Tablet and enzalutamide may drastically lower Bizo AM 5mg/2.5mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Bizo AM 5mg/2.5mg Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Coadministration of Bizo AM 5mg/2.5mg Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Bizo AM 5mg/2.5mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineSimvastatin
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Taking simvastatin with Bizo AM 5mg/2.5mg Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Bizo AM 5mg/2.5mg Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipinePhenobarbital
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Using phenobarbital and Bizo AM 5mg/2.5mg Tablet may drastically lower Bizo AM 5mg/2.5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Bizo AM 5mg/2.5mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Co-administration of Bizo AM 5mg/2.5mg Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Bizo AM 5mg/2.5mg Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineTizanidine
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Co-administration of Tizanidine and Bizo AM 5mg/2.5mg Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Bizo AM 5mg/2.5mg Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Bizo AM 5mg/2.5mg Tablet:
Coadministration of Bizo AM 5mg/2.5mg Tablet with itraconazole may significantly raise the blood levels and effects of Bizo AM 5mg/2.5mg Tablet.

How to manage the interaction:
Bizo AM 5mg/2.5mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL-2.5MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL-2.5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Bizo AM 5mg/2.5mg Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mmHg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. Low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Bizo AM 5mg/2.5mg Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Bizo AM 5mg/2.5mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Bizo AM 5mg/2.5mg Tablet should not be taken until prescribed. Bizo AM 5mg/2.5mg Tablet can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Bizo AM 5mg/2.5mg Tablet is usually not recommended in breastfeeding mothers. Limited human data available suggests that the drug does not do any significant harm to the baby. Consume only if benefits outweigh risks.

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Driving

Unsafe

It is not recommended to drive after taking Bizo AM 5mg/2.5mg Tablet as it may occasionally cause drowsiness or fatigue.

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Liver

Caution

Bizo AM 5mg/2.5mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Bizo AM 5mg/2.5mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Bizo AM 5mg/2.5mg Tablet is not recommended in children. The safety and efficacy of Bizo AM 5mg/2.5mg Tablet in children have not yet been established.

FAQs

Bizo AM 5mg/2.5mg Tablet is used to treat high blood pressure. It works by relaxing the blood vessels, reducing the workload on the heart, and increasing the heart's efficiency in pumping blood throughout the body.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Usually, Bizo AM 5mg/2.5mg Tablet is prescribed for long-term or lifelong treatment for heart-related chronic conditions and disorders. You should follow the doctor's advice and take it until your doctor tells you to stop. Suddenly stopping taking Bizo AM 5mg/2.5mg Tablet may raise your blood pressure and increase your risk of a heart attack.

Your doctor may probably tell you to stop taking Bizo AM 5mg/2.5mg Tablet as it lowers blood pressure (hypotension) when combined with general anaesthesia before surgery. So, please inform your doctor before surgery if you are taking Bizo AM 5mg/2.5mg Tablet.

If you have missed a dose of Bizo AM 5mg/2.5mg Tablet, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place. If it is time for you to take your next dose, do not take both doses together. Take only one dose; taking a double dose of Bizo AM 5mg/2.5mg Tablet will lead to low blood pressure.

Yes, Bizo AM 5mg/2.5mg Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists, consult your doctor and do what is advised.

Yes, Bizo AM 5mg/2.5mg Tablet can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Bizo AM 5mg/2.5mg Tablet. If you still feel excessively thirsty, please consult your doctor and do as advised for best results of Bizo AM 5mg/2.5mg Tablet.

Bizo AM 5mg/2.5mg Tablet contains Amlodipine and Bisoprolol. Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol helps relax the blood vessels by blocking the action of certain natural substances in the body. This lowers blood pressure and helps in reducing the risk of stroke, heart attack, other heart problems, or kidney problems in the future.

The side effects of Bizo AM 5mg/2.5mg Tablet include fatigue (overtiredness), dizziness, headache, cold hands and feet, bradycardia (slow heart rate) and nausea. If these side effects persist or worsen, please consult your doctor.

No, Bizo AM 5mg/2.5mg Tablet has no habit-forming tendencies.

Uncontrolled high blood pressure may lead to severe complications in various body parts. It can result in kidney damage, heart failure, bleeding in the eyes and brain.

Yes, Bizo AM 5mg/2.5mg Tablet may cause dizziness as a side effect. This may occur when you suddenly get up from sitting or lying position. To reduce the chance of feeling dizzy or passing out, get up slowly if you have been lying down or sitting.

Store Bizo AM 5mg/2.5mg Tablet below 30°C. Protect from light and moisture. Keep it out of reach and sight of children.

Bizo AM 5mg/2.5mg Tablet is contraindicated in patients who are allergic to amlodipine, bisoprolol or any of its ingredients and in patients with a history of asthma or lung disease. Also, tell your doctor about your medical history and the medicines you may be taking.

Yes, Bizo AM 5mg/2.5mg Tablet can cause headaches at the beginning of the treatment. Usually, headaches disappear after the first week of the treatment. However, if the headaches are frequent and persistent, contact your doctor.

Manufacturer/Marketer address

R.O.: #4 Sidco Complex,Near BB21 Feeder , B.Brahmana, Jammu 181133, MOB.8815108842
Other Info - BI17245

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 17, 2025 | 2:27 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6126.pdf
  2. https://patient.info/medicine/bisoprolol-a-beta-blocker-cardicor-congescor
  3. https://www.drugs.com/drug-interactions/amlodipine-index.html?filter=3
  4. https://www.drugs.com/drug-interactions/bisoprolol.html
  5. https://www.medicines.org.uk/emc/files/pil.2743.pdf
  6. https://www.nhs.uk/medicines/amlodipine/
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