Bisolet H 2.5mg/6.25mg Tablet

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Composition:BISOPROLOL-2.5MG+HYDROCHLOROTHIAZIDE-6.25MG

Prescription Medicine

Bisolet H 2.5mg/6.25mg Tablet is used in the treatment of high blood pressure. It effectively lowers elevated blood pressure and supports better heart function. By maintaining normal blood pressure, this combination helps reduce the risk of heart attack, stroke, heart failure, and kidney complications associated with long-term hypertension.

Written By Veda Maddala , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

BISOPROLOL-2.5MG+HYDROCHLOROTHIAZIDE-6.25MG

Manufacturer/Marketer :

Innovative Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Bisolet H 2.5mg/6.25mg Tablet

Bisolet H 2.5mg/6.25mg Tablet is primarily used to treat high blood pressure. High blood pressure is a condition in which the force of the blood against the artery walls is too high, leading to hypertension.

Bisolet H 2.5mg/6.25mg Tablet contains bisoprolol and hydrochlorothiazide. It relaxes the blood vessels and removes extra water/fluid from the body. Thereby, it helps treat high blood pressure.

Take Bisolet H 2.5mg/6.25mg Tablet as prescribed by your doctor. Bisolet H 2.5mg/6.25mg Tablet may cause side effects such as dizziness, weakness, diarrhoea, nausea, headache, and indigestion. Most of these side effects of Bisolet H 2.5mg/6.25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Bisolet H 2.5mg/6.25mg Tablet, please inform your doctor if you have any allergies, heart disease, asthma, diabetes, thyroid, glaucoma, kidney/liver disease, gout or if you cannot pass urine. Notify your doctor if you are pregnant or breastfeeding.

Uses of Bisolet H 2.5mg/6.25mg Tablet

Bisolet H 2.5mg/6.25mg Tablet is used in the treatment of high blood pressure (hypertension). The detailed uses of Bisolet H 2.5mg/6.25mg Tablet are as follows:

Management of Hypertension: Bisolet H 2.5mg/6.25mg Tablet helps to lower high blood pressure by relaxing the blood vessels, reducing heart rate, and increasing urine production.

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Directions for Use

Bisolet H 2.5mg/6.25mg Tablet can be taken with or without food as advised by your doctor.
Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
Swallow Bisolet H 2.5mg/6.25mg Tablet as a whole with a glass of water.
Do not chew, crush, or break it.

Key Benefits

Reduces blood pressure effectively, particularly in cases of moderate to severe hypertension.
Offers more effective and durable blood pressure management than single-drug therapy.
Removes excess fluid and salts from the body, helping maintain healthy blood pressure levels.
Lowers the risk of serious complications such as heart attack and stroke.
Provides cardiovascular protection by reducing strain on the heart and blood vessels.
Helps patients with chronic high blood pressure avoid kidney damage.

How Bisolet H 2.5mg/6.25mg Tablet Works

Bisolet H 2.5mg/6.25mg Tablet contains bisoprolol (beta-blocker) and hydrochlorothiazide (diuretic). • Bisoprolol relaxes the blood vessels by blocking the action of certain natural substances in the body. It helps slow down the heart rate, making it easier to pump blood around the body. • Hydrochlorothiazide lowers blood pressure by removing extra water/fluid and certain electrolyte overload from the body.

Storage

Store in a cool and dry place away from sunlight

Side effects of Bisolet H 2.5mg/6.25mg Tablet

Slow Heart Rate

Exercising regularly helps lower the risk of heart problems.
Maintain a healthy diet, including vegetables and fruits.
Rest well; get enough sleep.
Manage stress with yoga and meditation.
Limit alcohol and smoking.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Chest Pain

Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
Take rest and refrain from doing physical activity for a while, and restart after a few days.
Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Swelling In The Feet And Ankles

Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
Gently massage the swollen area with firm but not painful pressure.
Keep the swollen area clean and moisturized to prevent injury and infection.
Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Bisolet H 2.5mg/6.25mg Tablet

Do not take more than the prescribed dose of Bisolet H 2.5mg/6.25mg Tablet as it may cause an overdose. The symptoms of overdose include a very slow heartbeat, fainting, severe weakness, trouble breathing or severe dizziness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Bisolet H 2.5mg/6.25mg Tablet if you are allergic to any of its components.
Inform your doctor if you have heart problems, asthma, diabetes, thyroid problems, glaucoma, gout, kidney/liver problems or if you are unable to urinate.
Please do not abruptly discontinue Bisolet H 2.5mg/6.25mg Tablet, as this worsens the condition.
Bisolet H 2.5mg/6.25mg Tablet is not recommended for children younger than 18 years of age.

Drug-Drug Interactions

HydrochlorothiazideCisapride

Critical

HydrochlorothiazideDofetilide

Critical

Drug-Drug Interactions

HydrochlorothiazideCisapride

Critical

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Taking Cisapride and Bisolet H 2.5mg/6.25mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Bisolet H 2.5mg/6.25mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

HydrochlorothiazideDofetilide

Critical

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Taking Dofetilide and Bisolet H 2.5mg/6.25mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Bisolet H 2.5mg/6.25mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

BisoprololVerapamil

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Co-administration of Bisolet H 2.5mg/6.25mg Tablet with Verapamil can lead to increased risk or severity of side effects.

How to manage the interaction:
Although there may be an interaction, Bisolet H 2.5mg/6.25mg Tablet can be taken with verapamil if prescribed by the doctor. Consult a prescriber if you experience headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

BisoprololCeritinib

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Co-administration of ceritinib together with Bisolet H 2.5mg/6.25mg Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Bisolet H 2.5mg/6.25mg Tablet and ceritinib, but it can taken together if prescribed by the doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue the medication without consulting a doctor.

BisoprololAtenolol

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
When Bisolet H 2.5mg/6.25mg Tablet is combined with Atenolol the severity or risk of side effects may be increased.

How to manage the interaction:
Although there may be an interaction, atenolol can be taken with Bisolet H 2.5mg/6.25mg Tablet if prescribed by the doctor. Consult the prescriber if you experience any unusual side effects. Do not discontinue the medication without consulting a doctor.

BisoprololSaquinavir

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Co-administration of Bisolet H 2.5mg/6.25mg Tablet with Saquinavir may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there may be an interaction, Bisolet H 2.5mg/6.25mg Tablet can be taken with Saquinavir if prescribed by the doctor. Consult the prescriber if you develop dizziness, lightheadedness, fainting, or slow or irregular heart rate. Do not discontinue the medication without consulting a doctor.

BisoprololGlimepiride

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Concomitant use of Bisolet H 2.5mg/6.25mg Tablet with glimepiride may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.

How to manage the interaction:
Although there may be an interaction, Bisolet H 2.5mg/6.25mg Tablet can be taken with glimepiride if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.

BisoprololDolasetron

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Co-administration of Bisolet H 2.5mg/6.25mg Tablet with Dolasetron may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there may be an interaction, Bisolet H 2.5mg/6.25mg Tablet can be taken with Dolasetron if prescribed by the doctor. Consult the prescriber if you experience sudden dizziness, fainting, lightheadedness, or irregular heartbeat. Do not discontinue the medication without consulting a doctor.

BisoprololTizanidine

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Co-administration of Bisolet H 2.5mg/6.25mg Tablet and Tizanidine may increase the risk of low blood pressure.

How to manage the interaction:
Although there may be an interaction, Bisolet H 2.5mg/6.25mg Tablet can be taken with Tizanidine if prescribed by the doctor. If you experience headache, dizziness, lightheadedness, or palpitations. Do not discontinue the medication without consulting a doctor.

BisoprololAminophylline

Severe

How does the drug interact with Bisolet H 2.5mg/6.25mg Tablet:
Co-administration of Aminophylline with Bisolet H 2.5mg/6.25mg Tablet could reduce the metabolism of Aminophylline which increased the levels and enhance the effects of Aminophylline.

How to manage the interaction:
Taking aminophylline and Bisolet H 2.5mg/6.25mg Tablet together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, Contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Healthy eating habits:

Reduce your intake of packaged, processed, and fried foods, as they are high in salt.
Avoid refined carbs and sweets to support cardiovascular health.

Weight management

Increase your intake of fruits, vegetables, healthy grains, and lean proteins while maintaining a calorie-restricted, balanced diet.
Most days of the week, partake in regular physical activities like yoga, swimming, cycling, or brisk walking.

Lifestyle changes

Avoid alcohol, tobacco, and smoking since they raise your risk of cardiovascular disease.
Maintain a consistent sleep pattern and make sure you get enough sleep.

Stress Management:

Avoid chronic stress, as it can increase blood pressure levels.
Spend quality time with loved ones to promote emotional well-being.
Practice mindfulness techniques to help manage daily stress.

Habit Forming

Therapeutic Class

[ANTI- HYPERTENSIVES]

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Bisolet H 2.5mg/6.25mg Tablet to avoid unpleasant side effects.

Pregnancy

Consult your doctor

It is not known whether this Bisolet H 2.5mg/6.25mg Tablet will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

Breast Feeding

Unsafe

Bisolet H 2.5mg/6.25mg Tablet can pass into breast milk and may harm newborn babies. You should not breast-feed while using this Bisolet H 2.5mg/6.25mg Tablet.

Driving

Caution

It is not recommended to drive after taking Bisolet H 2.5mg/6.25mg Tablet as it may occasionally cause drowsiness or fatigue.

Liver

Caution

Bisolet H 2.5mg/6.25mg Tablet to be taken with caution, especially if you have a history of liver diseases. Your doctor may adjust your dose depending on your current liver conditions.

Kidney

Caution

Bisolet H 2.5mg/6.25mg Tablet to be taken with caution, especially if you have a history of Kidney diseases. Your doctor may adjust your dose depending on your current kidney conditions.

Children

Unsafe

Bisolet H 2.5mg/6.25mg Tablet is not recommended for children below 18 years.

Heart

Safe if prescribed

Bisolet H 2.5mg/6.25mg Tablet is safe for use in heart patients if recommended by the physician.

Geriatrics

Caution

Bisolet H 2.5mg/6.25mg Tablet should be used under caution in geriatric patients. Please consult your physician.

Country of origin

India

Other Info - BI93592

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Feb 12, 2026 | 1:24 PM IST

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