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  1. Home
  2. Medicine

  3. Bioproex-250 Tab 10'S

Prescription drug
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Bioproex-250 Tab 10'S, Pack of 10
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Extra 15% Off with Bank Offers

Composition :

DIVALPROEX-250MG

Manufacturer/Marketer :

Bio-well Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bioproex-250 Tab

Bioproex-250 Tab is used to treat epilepsy/seizures/fits. Additionally, Bioproex-250 Tab is also used to treat manic episodes associated with bipolar disorder and prevent migraines. Epilepsy is a sudden rush of electricity in the brain.

Bioproex-250 Tab contains 'Divalproex', which reduces excessive, abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Bioproex-250 Tab increases the levels of the chemical substance GABA; this helps block nerve transmission in the brain and produces a calming effect. Thereby helping treat bipolar disorder.

In some cases, you may experience side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Talk to your doctor if you experience these side effects persistently.

Do not take Bioproex-250 Tab if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Bioproex-250 Tab . Consult your doctor if you are breastfeeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Bioproex-250 Tab

Bioproex-250 Tab is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Bioproex-250 Tab are as follows:

  • Seizure Management: Bioproex-250 Tab is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.
  • Bipolar Disorder Treatment: Bioproex-250 Tab can be utilised in the treatment of bipolar disorder, aiding in mood stabilisation and reducing the frequency of mood swings.
  • Migraine Prevention: Bioproex-250 Tab may also be prescribed to prevent migraines, providing relief from recurrent headaches.

Have a query?

Directions for Use

  • Bioproex-250 Tab can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Bioproex-250 Tab as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Bioproex-250 Tab is used to treat and prevent epilepsy, seizures, or fits by controlling abnormal electrical activity in the brain.
  • It helps manage various types of seizures, including simple partial, complex partial, and absence seizures.
  • Bioproex-250 Tab may be used alone or in combination with other anti-epileptic medicines for better seizure control.
  • It is also prescribed to treat mood disorders, such as bipolar disorder, by enhancing GABA (gamma-aminobutyric acid) activity in the brain, which produces a calming and stabilising effect.
  • Bioproex-250 Tab helps prevent migraine headaches by reducing abnormal nerve transmission and limiting the spread of pain signals.
  • By decreasing excessive nerve activity, Bioproex-250 Tab restores normal brain function and helps maintain emotional balance.
  • Bioproex-250 Tab provides broad neurological benefits by controlling seizures, stabilising mood, and reducing migraine frequency.

How Bioproex-250 Tab Works

Bioproex-250 Tab contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Bioproex-250 Tab increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Bioproex-250 Tab
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Bioproex-250 Tab

Do not take more than the prescribed dose of Bioproex-250 Tab as it may cause overdose resulting in heart block, excess sleepiness and deep coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Bioproex-250 Tab if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders.
  • Inform your doctor before taking Bioproex-250 Tab if you have pancreatitis, blood problems or multi-organ hypersensitivity.
  • Consult your doctor immediately if you experience suicidal tendencies while taking Bioproex-250 Tab .
  • Bioproex-250 Tab may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems.
  • Please do not stop taking Bioproex-250 Tab without consulting your doctor to avoid worsening of seizures.
  • Do not take Bioproex-250 Tab if you are pregnant, as it could cause serious birth defects.
  • If you are of childbearing age, use effective contraception while taking Bioproex-250 Tab .
  • Consult your doctor before taking Bioproex-250 Tab if you are breastfeeding.
  • Avoid driving or operating machinery as Bioproex-250 Tab causes dizziness and may affect thinking and motor skills.
  • Avoid consuming alcohol along with Bioproex-250 Tab as it could lead to increased dizziness.
  • Care should be taken while giving Bioproex-250 Tab to children below 2 years, as there is a higher risk of liver intoxication during the first six months of treatment.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateDoripenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Bioproex-250 Tab:
Combining Sodium phenylbutyrate and Bioproex-250 Tab can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Bioproex-250 Tab is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Bioproex-250 Tab with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Bioproex-250 Tab can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Leflunomide and Bioproex-250 Tab can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Bioproex-250 Tab can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Bioproex-250 Tab:
The combined use of Ertapenem and Bioproex-250 Tab can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Bioproex-250 Tab can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Lithium with Bioproex-250 Tab can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Bioproex-250 Tab can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Bioproex-250 Tab:
Using buprenorphine together with Bioproex-250 Tab may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Bioproex-250 Tab can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Ketamine and Bioproex-250 Tab can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Bioproex-250 Tab can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Meropenam and Bioproex-250 Tab together can reduce the effect of Bioproex-250 Tab.

How to manage the interaction:
Co-administration of Meropenam and Bioproex-250 Tab can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Teriflunomide and Bioproex-250 Tab can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Bioproex-250 Tab can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Bioproex-250 Tab:
Co-administration of Vorinostat with Bioproex-250 Tab can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Bioproex-250 Tab can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, help those around you know what to do.
  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Bioproex-250 Tab Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Bioproex-250 Tab as it may cause increased dizziness.

bannner image

Pregnancy

Unsafe

Bioproex-250 Tab belongs to pregnancy category D. Avoid taking Bioproex-250 Tab if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

bannner image

Breast Feeding

Caution

Bioproex-250 Tab may pass into breastmilk. Consult your doctor before taking Bioproex-250 Tab if you are breastfeeding.

bannner image

Driving

Unsafe

Bioproex-250 Tab causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery.

bannner image

Liver

Caution

Bioproex-250 Tab should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Bioproex-250 Tab can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below two years, as they are at a higher risk of liver toxicity.

FAQs

Bioproex-250 Tab is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines.

Bioproex-250 Tab decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Bioproex-250 Tab helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, which helps in blocking the nerve transmission across the brain and provides a calming effect.

Bioproex-250 Tab limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Bioproex-250 Tab may interact with aspirin and cause abnormal side-effects. So, it is recommended to take any medication along with Bioproex-250 Tab only after consulting a doctor.

Bioproex-250 Tab may improve the symptoms of depression. However, do not use it without consulting a doctor as it may also cause mood disturbances and suicidal thoughts in some patients.

Do not discontinue Bioproex-250 Tab without consulting your doctor. To treat your condition effectually, continue taking Bioproex-250 Tab for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Bioproex-250 Tab ; your doctor will gradually reduce the dose to avoid worsening seizures.

Before taking Bioproex-250 Tab , certain laboratory tests are recommended. These include a Complete Blood Count (CBC), liver function tests (LFTs), kidney function tests, blood urea nitrogen (BUN) and creatinine levels, and a pregnancy test for women of childbearing age. Additionally, blood glucose levels should be checked for patients with diabetes or at risk of developing diabetes. Platelet count and coagulation tests (PT/INR/APTT) are also recommended. Please note that this list may not be exhaustive, and additional tests or monitoring may be necessary based on individual circumstances.

Bioproex-250 Tab may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Bioproex-250 Tab .

Topiramate (anticonvulsant) should not be taken along with Bioproex-250 Tab as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

It's crucial to consult with your doctor before discontinuing Bioproex-250 Tab . Abruptly stopping this medication can lead to severe consequences, especially if it's prescribed to treat conditions like epilepsy.

Bioproex-250 Tab is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.

Bioproex-250 Tab can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, you must talk to your doctor.

Yes, Bioproex-250 Tab can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Bioproex-250 Tab , it's essential to consult with your doctor.

Yes, Bioproex-250 Tab can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Bioproex-250 Tab , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Bioproex-250 Tab as it may cause increased dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Bioproex-250 Tab , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Bioproex-250 Tab can be a severe medical emergency. If you or someone you know has taken an overdose of Bioproex-250 Tab , it's crucial to seek immediate medical attention.

Bioproex-250 Tab can be taken with or without food. However, it is recommended to take it with food to reduce stomach upset and improve absorption. Food can help buffer any potential stomach irritation and enhance the body's absorption of the medication.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

SHOPNO.1,LGF, H.NO.153,HAUZ RANI MALVIYA NAGAR DELHI South Delhi DL 110017 IN
Other Info - BIO1914

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 4, 2025 | 9:20 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=e26005ef-77f0-4393-a2dc-b5fe460cead8&type=display
  3. https://www.drugs.com/mtm/divalproex-sodium.html
  4. https://www.depakote.com/depakote-formulations
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