Bioplegia Injection | Uses, Side Effects, Price

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Composition:MAGNESIUM CHLORIDE-3.25GM+POTASSIUM CHLORIDE-1.19GM+PROCAINE-0.27GM

Prescription Medicine

Bioplegia Injection is a cardioprotective medication used to induce cardioplegia (temporarily stop the heart) during heart surgeries such as heart valve replacement or a heart transplant. This medicine contains Magnesium chloride, Potassium chloride, and Procaine, which work by temporarily stopping the heart from beating and decreasing the sensation of pain by blocking nerve impulses. Let your doctor know if you are taking any medications or have any pre-existing medical conditions before receiving Bioplegia Injection.

Written By ,

Reviewed By Santoshini Reddy G , M Pharmacy

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More about the Product

Composition :

MAGNESIUM CHLORIDE-3.25GM+POTASSIUM CHLORIDE-1.19GM+PROCAINE-0.27GM

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bioplegia Injection

Bioplegia Injection is a cardioprotective medication used to induce cardioplegia during heart surgeries that involve cardiopulmonary bypass. It is commonly used in procedures such as heart valve replacement and heart transplants to keep a donated heart safe. Cardioplegia is a treatment administered during heart surgeries to deliberately and temporarily stop the heart, helping to protect the heart muscle (myocardium).

Bioplegia Injection contains Magnesium chloride (an electrolyte), Potassium chloride (an electrolyte), and Procaine (a local anaesthetic). Magnesium Chloride and Potassium Chloride lower the heart's oxygen demand by calming its electrical activity, which prevents muscle damage during heart surgery. Procaine decreases the sensation of pain by blocking the transmission of nerve impulses.

A trained healthcare professional will administer Bioplegia Injection through an infusion during surgery; do not self-administer. Consult the doctor immediately if you experience unusual symptoms after surgery, such as nausea, muscle twitching, tremors, convulsions, or irregular/slow heartbeat.

Before receiving Bioplegia Injection, inform your doctor if you are allergic to any of its ingredients. Also, let your doctor know if you are taking any prescription or non-prescription medications, vitamins, and herbal supplements or have any pre-existing medical conditions to rule out any side effects or interactions. Please consult your doctor if you are pregnant or breastfeeding before receiving Bioplegia Injection.

Uses of Bioplegia Injection

Bioplegia Injection is used to induce cardioplegia during heart surgery. The detailed uses of Bioplegia Injection are as follows:

Induces Cardioplegia (Heart Arrest): Bioplegia Injection helps stop the heart from beating, allowing surgeons to perform delicate procedures and is used in open-heart surgeries to protect the heart muscle.
Acts as a Local Anesthetic: Bioplegia Injection is used to reduce discomfort during medical procedures.
Maintains Electrolyte Balance: Bioplegia Injection is essential for nerve function and muscle contraction and helps restore electrolyte levels in patients undergoing surgery.

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Directions for Use

Follow your doctor’s instructions on the dosage and timing of this medication.
Bioplegia Injection will be administered by a healthcare professional in a medical setting.
Do not self-administer.

Key Benefits

Bioplegia Injection is a cardioprotective medication used to induce cardioplegia (temporarily stop the heart) during heart surgeries that involve cardiopulmonary bypass. It is commonly used in procedures such as heart valve replacement and heart transplants to keep a donated heart safe. It contains Magnesium chloride, Potassium chloride, and Procaine. Potassium chloride works by increasing potassium levels, which causes the heart muscle to contract. This action triggers the release of calcium ions, temporarily pausing the activity of the heart. Magnesium chloride also works by reducing the heart’s contractions. Together, they lower the heart's oxygen demand by calming its electrical activity, which prevents muscle damage while the heart is temporarily stopped during surgery. Procaine works by blocking the transmission of nerve impulses, which helps decrease the sensation of pain.

How Bioplegia Injection Works

Bioplegia Injection contains a combination of three drugs: Magnesium chloride (an electrolyte), Potassium chloride (an electrolyte), and Procaine (a local anaesthetic). It works by stopping the heart from beating and minimising the energy requirements of the heart during surgery. It also helps prevent disturbances in heart rhythm straight after the surgery.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Bioplegia Injection

Bioplegia Injection is administered in a controlled medical setting by a healthcare professional, so an overdose is not likely to occur. If an overdose occurs, it will be treated quickly by your doctor. Signs of an overdose may include difficulty breathing (apnoea), reduced blood flow due to weakened heart function (circulatory depression), seizures (fits), and a reduced ability of the blood to carry oxygen (methaemoglobinaemia).

Drug Warnings

Before receiving Bioplegia Injection, inform your doctor if you are allergic to any of its ingredients. Also, let your doctor know if you are taking any prescription or non-prescription medications, vitamins, and herbal supplements or have any pre-existing medical conditions to rule out any side effects or interactions. It is not known whether Bioplegia Injection can harm an unborn baby during pregnancy or pass into breast milk during breastfeeding. Therefore, please consult your doctor if you are pregnant or breastfeeding before receiving Bioplegia Injection.

Drug-Drug Interactions

Potassium chlorideClemastine

Critical

Potassium chlorideTrospium

Critical

Drug-Drug Interactions

Potassium chlorideClemastine

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Clemastine and Bioplegia Injection 20ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clemastine with Bioplegia Injection 20ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Potassium chlorideTrospium

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Trospium with Bioplegia Injection 20ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Trospium with Bioplegia Injection 20ml is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Potassium chlorideDicyclomine

Critical

How does the drug interact with Bioplegia Injection 20ml:
Co-administration of Dicyclomine with Bioplegia Injection 20ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Dicyclomine with Bioplegia Injection 20ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.

Potassium chlorideOrphenadrine (chloride)

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Orphenadrine and Bioplegia Injection 20ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Orphenadrine (chloride) with Bioplegia Injection 20ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Potassium chlorideDexchlorpheniramine

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Dexchlorpheniramine and Bioplegia Injection 20ml can increase the risk of stomach inflammation.

How to manage the interaction:
Taking Dexchlorpheniramine with Bioplegia Injection 20ml (in tablet or capsule form) is avoided as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, lightheadedness, vomiting, or dark stools, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Potassium chlorideMepenzolate

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Mepenzolate and Bioplegia Injection 20ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Mepenzolate with Bioplegia Injection 20ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Potassium chlorideOrphenadrine (citrate)

Critical

How does the drug interact with Bioplegia Injection 20ml:
Combining Orphenadrine with Bioplegia Injection 20ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Orphenadrine (citrate) with Bioplegia Injection 20ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Potassium chlorideOlanzapine

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Olanzapine with Bioplegia Injection 20ml can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Olanzapine and Bioplegia Injection 20ml is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Potassium chlorideclidinium bromide

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Bioplegia Injection 20ml with clidinium bromide may increase the risk of irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Bioplegia Injection 20ml with clidinium bromide is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms such as severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), decreased hunger, black, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Potassium chlorideCyproheptadine

Critical

How does the drug interact with Bioplegia Injection 20ml:
Taking Cyproheptadine with Bioplegia Injection 20ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Cyproheptadine with Bioplegia Injection 20ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop any medication without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Habit Forming

Therapeutic Class

[MISCELLANEOUS]

Alcohol

Consult your doctor

It is not known if alcohol interacts with Bioplegia Injection. Please consult your doctor before consuming alcohol.

Pregnancy

Consult your doctor

There is no information available about the use of Bioplegia Injection during pregnancy. Please consult your doctor if you have any concerns regarding the use of Bioplegia Injection during pregnancy.

Breast Feeding

Consult your doctor

It is not known if Bioplegia Injection passes into breastmilk. Please consult your doctor if you have any concerns regarding the use of Bioplegia Injection during breastfeeding.

Driving

Caution

Avoid driving and operating machinery until your doctor confirms that it is safe to do so.

Liver

Consult your doctor

Please consult your doctor before receiving Bioplegia Injection if you have liver problems.

Kidney

Consult your doctor

Please consult your doctor before receiving Bioplegia Injection if you have kidney problems.

Children

Consult your doctor

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Bioplegia Injection in children.

Heart

Consult your doctor

Inform your doctor if you have heart problems before using Bioplegia Injection.

Geriatrics

Consult your doctor

Bioplegia Injection can be given to geriatrics. If you have any concerns regarding the use of Bioplegia Injection, please consult a doctor.

FAQs

What is the use of Bioplegia Injection?

Bioplegia Injection is a cardioprotective medication used to induce cardioplegia (temporarily stop the heart) during heart surgeries that involve cardiopulmonary bypass.

How does Bioplegia Injection work?

Bioplegia Injection works by stopping the heart from beating and minimizing the energy requirements of the heart during surgery. It also helps prevent disturbances in heart rhythm straight after the surgery.

What information should I share with my doctor before receiving Bioplegia Injection?

Inform the doctor if you are taking any prescription or non-prescription medications, vitamins, and herbal supplements or have any pre-existing medical conditions before receiving Bioplegia Injection to rule out any side effects or interactions. Also, let your doctor know if you are pregnant or breastfeeding.

How to store Bioplegia Injection?

Bioplegia Injection should be stored below 25ºC, protected from light.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Other Info - BIO0122

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Bioplegia Injection 20ml

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Drug-Food Interactions

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