Apollo
logo
Select Delivery Location

Bio PDF Gel is used to treat diabetic foot ulcers. It contains Becaplermin which works by stimulating the growth of cells involved in wound healing. In some cases, this medicine may cause side effects such as burning at the site of application and skin rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Manufacturer/Marketer :

Bion Therapeutics (I) Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bio PDF Gel

Bio PDF Gel is a specialised topical gel prescribed to help heal deep diabetic foot ulcers. It is used to treat neuropathic ulcers that extend into the tissue beneath the skin in patients who have adequate blood flow to the affected limb. By encouraging new tissue growth, it helps close stubborn wounds that have not healed with standard care alone.

To achieve the best results, you must apply Bio PDF Gel consistently once every day. While food intake does not affect this topical gel, managing your daily blood sugar levels and following specific foot-care practices are critical to support the healing process. Your doctor will guide you on how to clean and prepare the wound before each application.

Some people may experience mild side effects, such as minor skin irritation or redness around the treated area. If you experience signs of a skin infection, such as worsening pain, swelling, foul odour, or pus, you should contact your doctor immediately. Do not ignore these changes, as diabetic wounds require careful monitoring.

Talk to your doctor before starting this medicine if you have any pre-existing health conditions, especially circulation problems or peripheral arterial disease. Do not use this medicine if you have active cancer at the application site or a history of cancer, as growth factors can encourage abnormal cell division. Your doctor will evaluate if this treatment is safe for your health history.

Tell your healthcare team about any other skin creams, ointments, or dressings you use, as they can interact with Bio PDF Gel and stop it from working effectively. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor or pharmacist before using this gel. Older adults should also discuss their overall health status with their doctor to ensure safe application.

Uses of Bio PDF Gel

Bio PDF Gel supports wound healing by promoting tissue repair and regeneration.

  • Diabetic foot ulcers: Bio PDF Gel helps heal deep, chronic open sores on the feet and legs of diabetic patients by stimulating the growth of new, healthy tissue to cover the wound.

Key Benefits

The primary benefit of Bio PDF Gel is its ability to accelerate the body's natural wound-healing processes. For patients suffering from long-standing diabetic foot ulcers, this gel offers several real-world benefits:

  • Faster wound closure: It shortens the time it takes for deep, open ulcers to heal, helping you return to your normal routine sooner.
  • Reduced risk of complications: By closing the open wound more quickly, it lowers the risk of developing deep tissue or bone infections, which are common complications of untreated ulcers.
  • Support for natural tissue repair: It encourages the formation of healthy granulation tissue, ensuring the wound heals securely from the inside out.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Take a small amount of Bio PDF Gel onto a firm, clean, non-absorbable surface like wax paper. Then spread it evenly as a thin layer over the surface of the foot ulcer with the help of a clean cotton swab, tongue depressor, or any other application aid.
  • Cover the treated area with a gauze dressing moistened with saline.

How Bio PDF Gel Works

Bio PDF Gel contains recombinant human platelet derived growth factor bb, which works by mimicking a natural protein that your body produces to repair damaged tissues. When applied to a clean, prepared wound, the active growth factor attracts special repair cells that your body uses to rebuild damaged tissue to the ulcer site. Once these repair cells reach the wound, they multiply and help build new connective tissue and tiny blood vessels. This creates new tissue layer by layer inside the wound to gradually fill it in (a process called granulation). As the wound fills, new skin cells grow across the healthy tissue, helping the wound close safely.
bannner image

Alcohol

Caution

The interaction of Bio PDF Gel with alcohol is unknown. Please consult a doctor before consuming alcohol while using Bio PDF Gel .

bannner image

Pregnancy

Caution

Please consult a doctor if you are pregnant. Bio PDF Gel is given to pregnant women if the doctor thinks the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

It is unknown whether Bio PDF Gel is excreted in human milk. Therefore, Bio PDF Gel is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

bannner image

Driving

Safe if prescribed

Bio PDF Gel usually does not affect your ability to drive or operate machinery.

bannner image

Liver

Safe if prescribed

Please consult a doctor if you have any concerns about using Bio PDF Gel in patients with liver problems.

bannner image

Kidney

Safe if prescribed

Please consult a doctor if you have any concerns about using Bio PDF Gel in patients with kidney problems.

bannner image

Children

Unsafe

Bio PDF Gel is not recommended for children below 16 years as the safety and effectiveness were not established.

bannner image

Heart

Safe if prescribed

Bio PDF Gel is generally considered safe for heart patients when used at the prescribed amount. However, please consult your doctor if you have any concerns.

bannner image

Geriatrics

Safe if prescribed

Bio PDF Gel is generally considered safe for elderly patients when used as prescribed by a doctor. Consult your doctor if you have any concerns.

What if I have taken an overdose of Bio PDF Gel

Since this is a topical gel, a typical overdose is highly unlikely. However, applying too much gel or using it more often than prescribed can cause severe skin irritation. If you suspect someone has accidentally swallowed this gel, seek immediate medical attention.

Diet & Lifestyle Advise

  • Control your blood sugar: Consistently managing your blood glucose levels is the most important step you can take, as high blood sugar severely delays wound healing and increases infection risk.
  • Relieve pressure (Offloading): Avoid putting weight on the affected foot. Use therapeutic shoes, specialised casts, or offloading devices as recommended by your healthcare team to protect the healing ulcer.
  • Eat a protein-rich diet: Ensure your daily meals contain adequate protein, vitamin C, and zinc, which are vital nutrients your body needs to rebuild skin and tissue.
  • Avoid smoking: Quit smoking, as nicotine constricts blood vessels, reducing the delivery of oxygen and healing nutrients to your foot.
  • Check your feet daily: Inspect both feet every day for any new red spots, cuts, or blisters to prevent new ulcers from forming.
health query

Have a query?

How Soon It Starts Working

The time required for Bio PDF Gel to start to work: The time required for Bio PDF Gel to show its action is unknown. The time for which the effects of Bio PDF Gel last: The duration of action for Bio PDF Gel is clinically unknown.

What if you forget to take Bio PDF Gel

Apply the missed dose as soon as you remember. However, if it is almost time for your next daily application, skip the missed dose and continue with your regular schedule. Do not apply double the amount of gel to make up for a missed application.

Storage

• Store Bio PDF Gel in a refrigerator between 2°C and 8°C (36°F and 46°F).
icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the gel: Check the tube before use. Do not apply the gel if it appears discoloured, cloudy, or if the tube is damaged or leaking.
  • Avoid contamination: Never touch the tip of the tube directly to your wound, fingers, or any other surface to keep the remaining medicine sterile.
  • Limit the number of tubes: Do not use more than the prescribed number of tubes. Using large amounts of this class of medicine over a long period has been linked to an increased risk of serious health conditions, including cancer.
  • Do not mix treatments: Avoid applying other topical creams, ointments, or home remedies to the ulcer at the same time as Bio PDF Gel unless your doctor specifically tells you to.
  • Paediatric use: The safety and efficacy of Bio PDF Gel in children have not been established. Use only under medical supervision if prescribed.
  • Attend all follow-up visits: Regular visits to your doctor are essential so they can measure the wound, remove dead tissue, and monitor your overall progress.

verifiedApollotooltip

Some medicines and skin products may interact with Bio PDF Gel and affect how well it works.

  • Other topical medications: Do not apply other skin creams, ointments, antiseptic solutions, or dressings containing heavy metals (such as silver or zinc) to the ulcer. These substances can break down the proteins in Bio PDF Gel , making it completely ineffective.

Login/Sign Up

verifiedApollotooltip
  • No clinically significant food interactions are known with Bio PDF Gel when used as directed.

Login/Sign Up

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS TOPICAL]

FAQs

Bio PDF Gel contains Becaplermin, a platelet-derived growth factor that stimulates the growth of cells involved in wound healing. Thus, it helps treat ulcers of the legs or feet in people with diabetes.
Bio PDF Gel is not recommended for treating pressure ulcers or ulcers caused by poor blood flow. It is only used to treat diabetic foot ulcers in patients with a good blood supply.
You are recommended to use Bio PDF Gel for as long as your doctor has prescribed it. However, if the size of the ulcer is not a minimum of 1/3rd smaller in size after using Bio PDF Gel for 10 weeks or if the ulcer is not healed completely after 20 weeks, please consult a doctor.
Bio PDF Gel may temporarily cause a red skin rash. If the rash persists or worsens, please consult a doctor.
Bio PDF Gel belongs to the platelet-derived growth factors (PDGFs) class, which are used to treat diabetic foot ulcers in people with good blood flow in their legs and feet.
The common side effects of Bio PDF Gel may include burning at the application site and red skin rash. Most of these side effects of Bio PDF Gel do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
No, you should not use your bare fingers to apply this gel. Always use a sterile applicator, such as a cotton swab or a clean tongue depressor, to prevent introducing harmful bacteria to the open wound. Talk to your doctor if you need a demonstration on clean application techniques.
Yes, this gel must be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze it, and keep it away from the freezer compartment. Talk to your pharmacist if you have questions about proper storage during travel.
If you notice increased redness, swelling, oozing, a foul smell, or worsening pain, stop using the gel and contact your doctor immediately. These could be signs of a serious skin infection that requires prompt medical evaluation.
No, Bio PDF Gel is specifically approved only for treating deep neuropathic diabetic foot ulcers. It should not be used on surgical wounds, burns, or typical cuts unless specifically prescribed by your doctor. Talk to your doctor to find the right treatment for other types of skin wounds.
Growth factors like Bio PDF Gel can encourage cell division. Studies show that using three or more tubes of this class of medication may increase the risk of cancer-related complications. Always use the exact amount prescribed, do not exceed your prescribed number of tubes, and talk to your doctor about your health history.
You should not apply other creams, ointments, or topical products to the ulcer unless your doctor specifically instructs you to do so. Other products can interact with Bio PDF Gel and make it less effective. Talk to your doctor or pharmacist before combining any skin treatments.
Yes, the wound should be covered with a saline-moistened gauze dressing after applying the gel. This keeps the healing environment moist, which is essential for the medicine to work properly. Talk to your doctor for step-by-step wound dressing instructions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

303 & 304, Chakrapani Estate, Hilfort Road, Saifabad, Hyderabad, Telangana, India.
Other Info - BIO1479
whatsapp Floating Button
Buy Now
Add to Cart