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  3. Bigphylin Plus Tablet 10's

Bigphylin Plus Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Bigphylin Plus Tablet is a combination medicine mainly used to treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). This medicine works by reducing the secretions in the airway, improving the lung airflow by relaxing the muscles in the airways and thus helps relieve symptoms like coughing, wheezing and shortness of breath. Common side effects includenausea, vomiting, stomach upset, headache, and restlessness.
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Composition :

ACEBROPHYLLINE-200MG + DESLORATADINE-5MG + MONTELUKAST-10MG

Manufacturer/Marketer :

ZRS Labs

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bigphylin Plus Tablet

Bigphylin Plus Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Bigphylin Plus Tablet is a combination of three drugs: Acebrophylline (bronchodilator), Desloratadine (antihistamine), and Montelukast (leukotriene receptor antagonist). Acebrophylline works by relaxing muscles and widening the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. This helps to cough out easily and makes breathing easier by opening airways. Desloratadine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Montelukast works by blocking the action of chemicals called leukotrienes that cause inflammation (swelling) and increased mucus production in the airways. Thereby reducing inflammation, mucus production, and narrowing in the airways.   

Take Bigphylin Plus Tablet as prescribed. You are advised to take Bigphylin Plus Tablet for as long as your doctor has recommended it based on your medical condition. Some people may experience nausea, vomiting, stomach upset, headache, and restlessness. Most of these side effects of Bigphylin Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Bigphylin Plus Tablet or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma or experience chest tightness in the morning, please consult a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Bigphylin Plus Tablet . Do not take Bigphylin Plus Tablet if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Bigphylin Plus Tablet if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, kidney or liver diseases. 

Uses of Bigphylin Plus Tablet

Treatment of Asthma and Chronic obstructive pulmonary disease (COPD)

Directions for Use

• Take Bigphylin Plus Tablet with food to avoid stomach upset or as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Bigphylin Plus Tablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Bigphylin Plus Tablet contains Acebrophylline (bronchodilator), Desloratadine (antihistamine), and Montelukast (leukotriene receptor antagonist) used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Acebrophylline relaxes muscles and widens the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily and makes breathing easier by opening airways. Desloratadine is an anti-allergic drug that helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Montelukast reduces inflammation, mucus production and narrowing in the airways. Bigphylin Plus Tablet helps to prevent an asthma attack.

How Bigphylin Plus Tablet Works

Bigphylin Plus Tablet is a combination of three drugs: Acebrophylline (bronchodilator), Desloratadine (antihistamine), and Montelukast (leukotriene receptor antagonist). Acebrophylline works by relaxing muscles and widening the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. This helps to cough out easily and makes breathing easier by opening airways. Desloratadine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Montelukast works by blocking the action of chemicals called leukotrienes that cause inflammation (swelling) and increased mucus production in the airways. Thereby reducing inflammation, mucus production, and narrowing in the airways.

Storage

• Store in a cool and dry place away from sunlight.• Keep Bigphylin Plus Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Bigphylin Plus Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to Bigphylin Plus Tablet or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Bigphylin Plus Tablet as it may cause low potassium levels in the blood. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Bigphylin Plus Tablet . Do not take Bigphylin Plus Tablet if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Bigphylin Plus Tablet if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, kidney or liver diseases. 

Drug-Drug Interactions

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DesloratadineTranylcypromine
Severe
DesloratadineIsocarboxazid
Severe

Drug-Drug Interactions

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DesloratadineTranylcypromine
Severe
How does the drug interact with Bigphylin Plus Tablet:
Co-administration of Bigphylin Plus Tablet with Tranylcypromine may increase the risk or severity of CNS depression (decreased heart rate, decreased rate of breathing, loss of consciousness).

How to manage the interaction:
Although there is an interaction between Bigphylin Plus Tablet with tranylcypromine, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DesloratadineIsocarboxazid
Severe
How does the drug interact with Bigphylin Plus Tablet:
Co-administration of Bigphylin Plus Tablet with Isocarboxazid can increase the risk of CNS depression.

How to manage the interaction:
Taking Bigphylin Plus Tablet with Isocarboxazid together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
DesloratadineIvacaftor
Severe
How does the drug interact with Bigphylin Plus Tablet:
Co-administration of Ivacaftor and Bigphylin Plus Tablet can increase the levels of Bigphylin Plus Tablet.

How to manage the interaction:
Co-administration of Bigphylin Plus Tablet with Ivacaftor can possibly result in an interaction, but it can be taken if doctor has advised it. Do not stop using any medications without talking to a doctor.
MontelukastRifabutin
Severe
How does the drug interact with Bigphylin Plus Tablet:
Coadministration of Bigphylin Plus Tablet and rifabutin can reduce the levels and effects of Rifabutin. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Bigphylin Plus Tablet and rifabutin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience increased side effects such as headache, fever, sore throat, cough, abdominal pain, diarrhea, earache, runny nose, or behavior and mood changes consult a doctor. Do not discontinue any medications without consulting a doctor.
MontelukastPhenytoin
Severe
How does the drug interact with Bigphylin Plus Tablet:
Coadministration of Bigphylin Plus Tablet and Phenytoin may reduce the blood levels and effects of Bigphylin Plus Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Bigphylin Plus Tablet and Phenytoin may interact with one another, but they can be taken together if your doctor has prescribed them. However, if you experience signs such as headache, fever, sore throat, cough, abdominal pain, diarrhoea, earache, runny nose, or behaviour and mood changes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MontelukastPrimidone
Severe
How does the drug interact with Bigphylin Plus Tablet:
Coadministration of Bigphylin Plus Tablet and primidone can reduce the levels and effects of Bigphylin Plus Tablet.

How to manage the interaction:
Taking Bigphylin Plus Tablet and Primidone together can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MontelukastMiconazole
Severe
How does the drug interact with Bigphylin Plus Tablet:
Coadministration of Miconazole with Bigphylin Plus Tablet may increase the blood levels and effects of Bigphylin Plus Tablet. This increases the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between miconazole and Bigphylin Plus Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, sore throat, cough, stomach pain, diarrhea, earache, runny nose, or uncommon, depression, confusion, difficulty concentrating, anxiety, hallucinations, irritability. memory impairment, restlessness, sleep walking, Consult a doctor immediately. Do not stop using medications without a doctor's advice.
MontelukastRifapentine
Severe
How does the drug interact with Bigphylin Plus Tablet:
Coadministration of Rifapentine with Bigphylin Plus Tablet may reduce the blood levels and effects of Bigphylin Plus Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Rifapentine with Bigphylin Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience increased side effects such as headache, fever, sore throat, cough, abdominal pain, diarrhea, earaches, runny nose, or behavior and mood changes consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots as potassium is important for lung function and a deficiency in potassium may cause breathing problems.

  • Drink plenty of fluids every day to thin mucus which makes it easier to cough out. 

  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.

  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.

  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

  • Quit smoking as it may reduce the effectiveness of the Bigphylin Plus Tablet and irritate the lungs and worsen breathing problems.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Bigphylin Plus Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Bigphylin Plus Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol with Bigphylin Plus Tablet .

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Pregnancy

Caution

Bigphylin Plus Tablet is given to pregnant women only if the doctor thinks the benefits are greater than the risks. Therefore, please inform your doctor if you are pregnant before using Bigphylin Plus Tablet .

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Breast Feeding

Caution

It is unknown whether Bigphylin Plus Tablet is excreted in human milk. Please consult a doctor before taking Bigphylin Plus Tablet if you are breastfeeding.

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Driving

Caution

Drive only if you are alert after taking Bigphylin Plus Tablet as it may cause drowsiness or dizziness in some people.

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Liver

Caution

Take Bigphylin Plus Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Bigphylin Plus Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Bigphylin Plus Tablet should be used with caution in children in doses as prescribed by a doctor.

Have a query?

FAQs

Bigphylin Plus Tablet is used to prevent and treat asthma and chronic obstructive pulmonary disease (COPD) symptoms.

Bigphylin Plus Tablet contains Acebrophylline, Desloratadine and Montelukast. Acebrophylline relaxes muscles and widens the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily and makes breathing easier by opening airways. Desloratadine is an anti-allergic drug that helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Montelukast reduces inflammation, mucus production and narrowing in the airways.

Bigphylin Plus Tablet should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Bigphylin Plus Tablet so that the dose may be adjusted or an alternate medicine may be prescribed.

You are not recommended to take erythromycin with Bigphylin Plus Tablet as co-administration of these medicines may increase the risk of adverse effects of Bigphylin Plus Tablet . However, please consult a doctor before using other medicines with Bigphylin Plus Tablet .

You are recommended to avoid taking Bigphylin Plus Tablet if you are allergic to acebrophylline, ambroxol, theophylline or suffering from irregular heartbeats, hemodynamic instability (unstable blood pressure), low blood pressure, liver or kidney disorders or had a heart attack. However, inform your doctor if you have any of these conditions before taking Bigphylin Plus Tablet .

You are not recommended to smoke while taking Bigphylin Plus Tablet as it may reduce the effectiveness of Bigphylin Plus Tablet .

No, you are not recommended to stop taking Bigphylin Plus Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Bigphylin Plus Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Bigphylin Plus Tablet , please consult your doctor.

No, Bigphylin Plus Tablet does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

Country of origin

India

Manufacturer/Marketer address

Shop No-10 & 11, Pockt, H-32, Sector-3 Rohini, DELHI-110085, India
Other Info - BIG0136

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 6:58 AM IST

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Reference

  1. https://www.ciplamed.com/content/mucophylin-capsules
  2. https://www.drugs.com/mtm/desloratadine.html
  3. https://www.drugs.com/mtm/montelukast.html

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