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compositionComposition:AMILORIDE-2.5MG+HYDROCHLOROTHIAZIDE-25MG
prescription
Prescription Medicine
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BIDURET L TABLET is used to treat high blood pressure and fluid retention. It contains Amiloride and Hydrochlorothiazide which work by eliminating extra water and electrolytes from the body via urine. This medicine may sometimes cause side effects such as nausea, vomiting, diarrhoea, headache, glucose intolerance, weakness, muscle cramps, electrolyte imbalance, and increased uric acid levels in the blood. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

AMILORIDE-2.5MG+HYDROCHLOROTHIAZIDE-25MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About BIDURET L TABLET

BIDURET L TABLET is a prescription medication used to treat high blood pressure (hypertension) and fluid retention (oedema). It helps remove excess water and salt from the body while ensuring that essential minerals remain balanced. This medicine is commonly prescribed to manage fluid buildup associated with heart failure or liver disease.

For the best results, you should take BIDURET L TABLET consistently at the same time every day, usually in the morning to prevent nighttime bathroom trips. You can take this medicine with or without food, but it is important to choose one way and stick to it. Combining this treatment with a low-sodium diet and a regular exercise routine can significantly improve your results.

While taking this medicine, you may experience mild side effects like dizziness, headache, or a mild upset stomach. However, you must contact your doctor immediately if you experience serious side effects such as irregular heartbeats, severe muscle weakness, or signs of severe dehydration. Monitoring how you feel can help ensure you use this medicine safely.

Do not take this if you have severe kidney failure, already have dangerously high levels of potassium in your blood, or are allergic to sulfa-based medications. Before starting, talk to your doctor if you have diabetes, gout, or mild kidney problems, as your dose may need to be adjusted. Your doctor will help determine if this medication is safe for your specific health profile.

This medicine can interact with other treatments, including blood pressure drugs, lithium, and potassium supplements, which can lead to dangerously high potassium levels or kidney issues. It is also important to limit alcohol intake as it can worsen dizziness, and you should talk to your doctor if you are pregnant, breastfeeding, or elderly to ensure the medicine is appropriate for you.

Uses of BIDURET L TABLET

BIDURET L TABLET is used to manage conditions involving high blood pressure or excess fluid retention in the body. Its uses include:

  • High blood pressure (Hypertension): BIDURET L TABLET helps lower elevated blood pressure, which reduces the workload on your heart and lowers your risk of serious complications like strokes and heart attacks.
  • Fluid retention (Oedema): This medication helps your body eliminate excess water and salt that can build up due to conditions like congestive heart failure or liver disease, helping you breathe easier and reducing swelling.

Key Benefits

BIDURET L TABLET combines two diuretics that help remove excess fluid from the body while reducing excessive potassium loss. It is used to manage high blood pressure and fluid retention associated with certain medical conditions.

  • Reduces Fluid Retention: Helps remove excess fluid from the body, relieving swelling in the ankles, legs, and other affected areas.
  • Lowers High Blood Pressure: Helps reduce blood pressure by decreasing excess fluid and sodium in the body, lowering the risk of hypertension-related complications.
  • Improves Breathing Comfort: Reducing excess fluid build-up may help ease shortness of breath associated with fluid retention in certain conditions.
  • Helps Maintain Potassium Balance: Amiloride helps reduce the potassium loss that can occur with hydrochlorothiazide, lowering the risk of low potassium levels.
  • Supports Long-Term Cardiovascular Health: Effective blood pressure and fluid control helps reduce strain on the heart and protect vital organs from complications associated with uncontrolled hypertension.

Directions for Use

  • BIDURET L TABLET can be taken with food.
  • BIDURET L TABLET is usually taken once a day, or as prescribed by your doctor.
  • Swallow BIDURET L TABLET as a whole with a glass of water.
  • Do not crush, break, or chew it.

How BIDURET L TABLET Works

BIDURET L TABLET contains amiloride and hydrochlorothiazide, which work together to manage fluid and blood pressure levels while protecting your body's chemistry. The first active ingredient, hydrochlorothiazide, is a thiazide diuretic. It works directly in your kidneys to increase the filtration of salt and water out of your blood, prompting your body to release them through your urine. This action reduces the total volume of fluid circulating through your blood vessels, which naturally lowers your blood pressure and reduces swelling. The second active ingredient, amiloride, is a potassium-sparing diuretic. When kidneys filter out excess salt and water, they typically flush out potassium as well, which can lead to dangerous deficiencies. This second ingredient works on a different part of the kidney to prevent potassium loss, keeping your vital mineral levels balanced while the other ingredient removes excess fluid. Together, these actions help remove excess fluid, lower blood pressure, reduce swelling, and minimise potassium loss.
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Alcohol

Caution

Alcohol may cause dizziness. It would help if you avoided or limit consuming alcohol whilst taking BIDURET L TABLET.

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Pregnancy

Unsafe

BIDURET L TABLET is not recommended during pregnancy since it may cause harmful effects on the baby. It is advised to seek medical advice before using BIDURET L TABLET if you plan to conceive or pregnant.

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Breast Feeding

Unsafe

BIDURET L TABLET may pass into the breast milk during breastfeeding. Please consult your doctor before using BIDURET L TABLET if you are a lactating mother.

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Driving

Caution

BIDURET L TABLET may cause side effects such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using BIDURET L TABLET. BIDURET L TABLET is to be administered with caution in patients with severe hepatic impairment.

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Kidney

Caution

BIDURET L TABLET to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Unsafe

BIDURET L TABLET is not recommended for use in children below 18 years as the efficacy and safety have not been established.

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Heart

Safe if prescribed

BIDURET L TABLET is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

BIDURET L TABLET should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of BIDURET L TABLET

In case of an accidental overdose, seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include severe dizziness, fainting, extreme weakness, or an irregular heartbeat.

Diet & Lifestyle Advise

  • Limit Salt Intake: Reduce sodium in your diet, as excess salt can promote fluid retention and raise blood pressure.
  • Avoid Excess Potassium: Do not use potassium-containing salt substitutes or take potassium supplements unless specifically advised by your doctor, as amiloride may increase blood potassium levels.
  • Stand Up Slowly: Rise gradually from a sitting or lying position to reduce the risk of dizziness, lightheadedness, or falls.
  • Follow Fluid Advice: Maintain adequate hydration, but follow your doctor's specific recommendations if you have been advised to restrict fluids due to heart, liver, or kidney problems.
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How Soon It Starts Working

The time required for BIDURET L TABLET to start to work: BIDURET L TABLET starts to show its action within 1 to 2 hours of administration. The time for which the effects of BIDURET L TABLET last: BIDURET L TABLET effect lasts for 24 hours.

What if you forget to take BIDURET L TABLET

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take two doses at the same time to make up for a missed one.

Storage

• Store BIDURET L TABLET tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C). •Keep the medication container tightly closed to protect the tablets from moisture and direct light.

Drug Warnings

  • Attend Regular Blood Tests: Keep all scheduled appointments so your doctor can monitor your kidney function and electrolyte levels, particularly potassium.
  • Monitor Your Blood Pressure: Check your blood pressure regularly at home and maintain a record to share with your healthcare provider.
  • Avoid Alcohol: Alcohol may worsen dizziness, lightheadedness, and the risk of fainting while taking this medicine.
  • Protect Your Skin from Sunlight: Hydrochlorothiazide may increase sensitivity to sunlight. Use sunscreen, wear protective clothing, and limit prolonged sun exposure.
  • Inform Healthcare Providers: Tell your doctor, surgeon, dentist, or emergency medical team that you are taking BIDURET L TABLET before any procedure or treatment.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with BIDURET L TABLET and increase the risk of high potassium levels, kidney problems, or other adverse effects:

  • Potassium supplements or potassium-sparing diuretics: Combining these with BIDURET L TABLET can cause dangerously high potassium levels in your blood.
  • ACE inhibitors or ARBs: Taking these blood pressure medications alongside this treatment increases the risk of elevated blood potassium and kidney issues.
  • Lithium: This medicine can decrease the kidney's ability to remove lithium, leading to toxic levels of lithium in your system.
  • NSAIDs (like ibuprofen): These pain relievers can reduce the fluid-clearing effects of your medicine and increase the risk of kidney damage.
Amiloride + HydrochlorothiazideBenazepril
Severe
Amiloride + HydrochlorothiazideAmiodarone
Severe

Drug-Drug Interactions

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Amiloride + HydrochlorothiazideBenazepril
Severe
How does the drug interact with Biduret L Tablet:
Coadministration of Benazepril with Biduret L Tablet may cause a rise in potassium levels in the blood.

How to manage the interaction:
Although taking Biduret L Tablet and benazepril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience fatigue, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
Amiloride + HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Biduret L Tablet:
Coadministration of Amiodarone together with Biduret L Tablet may raise the risk of an abnormal heart rhythm. You may be at greater risk if you have cardiac problems or electrolyte imbalances.

How to manage the interaction:
Even though Amiodarone and Biduret L Tablet interact, they can be used if a doctor prescribes them. Contact your doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
Amiloride + HydrochlorothiazideArsenic trioxide
Severe
How does the drug interact with Biduret L Tablet:
Co-administration of Arsenic trioxide and Hydrochlorothiazide can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Arsenic trioxide and Hydrochlorothiazide together is avoided as it can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Amiloride + HydrochlorothiazideAminolevulinic acid
Severe
How does the drug interact with Biduret L Tablet:
Coadministration of Aminolevulinic acid with Biduret L Tablet can make your skin more sensitive to bright lights. This could increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolevulinic acid and Biduret L Tablet, it can be taken if advised by your doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
Amiloride + HydrochlorothiazideCaptopril
Severe
How does the drug interact with Biduret L Tablet:
Coadministration of Captopril with Biduret L Tablet may cause a rise in potassium levels in your blood.

How to manage the interaction:
Although taking Biduret L Tablet and captopril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
Amiloride + HydrochlorothiazideCandesartan
Severe
How does the drug interact with Biduret L Tablet:
When used with candesartan, Biduret L Tablet may raise potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest).

How to manage the interaction:
Although taking amiloride and candesartan together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Amiloride + HydrochlorothiazideAzilsartan medoxomil
Severe
How does the drug interact with Biduret L Tablet:
Co-administration of Azilsartan medoxomil with Biduret L Tablet may raise potassium levels in the blood.

How to manage the interaction:
Although taking Biduret L Tablet and Azilsartan medoxomil together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and dietary products may affect potassium levels while taking BIDURET L TABLET. Important interactions include:

  • Potassium-rich salt substitutes: Using these substitutes can lead to an unsafe buildup of potassium in your body.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[DIURETIC]

FAQs

BIDURET L TABLET is used to treat hypertension (high blood pressure) and oedema (fluid retention).
BIDURET L TABLET treats hypertension (high blood pressure), heart failure and oedema (fluid retention). BIDURET L TABLET consists of diuretic medications: Amiloride and hydrochlorothiazide. It works by acting on different parts of the kidney to remove extra fluid and certain electrolytes while maintaining the body's potassium balance. This BIDURET L TABLET helps in getting down the blood pressure as well as swelling.
Yes, the use of BIDURET L TABLET may cause dry mouth. If you feel dry mouth, drink plenty of water. Take normal sips during the day and keep some water at night. If your lips are also dry, you may use lip balm. Try to prevent foods that are spicy, acidic (like lemons), and salty.
Your doctor will examine your potassium levels in blood regularly for high potassium levels. Make sure that you do not forget any future meetings with the doctor.
BIDURET L TABLET can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
No, BIDURET L TABLET does not have habit-forming potential.
You are not recommended to stop taking BIDURET L TABLET even if you feel better, as you may experience severe complications. However, contact a doctor if you have any concerns.
BIDURET L TABLET may increase the risk of skin cancer. Therefore, if you have cancer, inform your doctor before starting BIDURET L TABLET.
Store BIDURET L TABLET at room temperature in a cool, dry place as advised on label. Protect from light and moisture. Keep it out of reach of children. BIDURET L TABLET should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
BIDURET L TABLET causes side effects such as nausea, vomiting, diarrhoea, headache, glucose intolerance, weakness, muscle cramps, electrolyte imbalance, and increased uric acid levels in the blood. Most of these side effects do not require any medical treatments as they gradually reduce over time. However, if these side effects continue, contact your doctor.
It is highly recommended to take BIDURET L TABLET in the morning. Taking this medicine close to bedtime will likely cause you to wake up during the night to urinate, which can disrupt your sleep. Talk to your doctor or pharmacist if you need to adjust your dosing schedule.
You should be cautious with your potassium intake. Because BIDURET L TABLET helps your kidneys retain potassium, consuming large amounts of potassium-rich foods can cause your blood potassium levels to become dangerously high. Talk to your doctor or pharmacist for personalised dietary advice.
In some cases, especially if you are dehydrated or taking other medications like NSAIDs, BIDURET L TABLET can affect your kidney function. Your doctor will monitor your kidneys with routine blood tests. Talk to your doctor or pharmacist if you notice a sudden decrease in your urine output.
It is best to avoid or limit alcohol while taking BIDURET L TABLET. Alcohol can amplify the blood-pressure-lowering effect of the medication, which can cause severe dizziness, lightheadedness, or fainting. Talk to your doctor about what is safe for you.
This medicine is generally not recommended during pregnancy unless your doctor decides that the benefits outweigh the risks to the baby. If you are pregnant or planning to become pregnant, talk to your doctor immediately to discuss alternative options.
Muscle cramps can be a sign of an electrolyte imbalance, such as high potassium or low sodium. You should contact your doctor right away so they can perform a blood test to check your mineral levels. Talk to your doctor or pharmacist for further guidance.

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Country of origin

India

Manufacturer/Marketer address

Stiefel India Ltd., 401& 402, A Wing, IV Floor, Floral Deck Plaza, Opp. Rolta Bhavan, Central MIDC Road, Andheri (East), Mumbai – 400093
Other Info - BID0005
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