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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bemzire-R 40 Tablet 1 is used to lower the levels of bad cholesterol called low-density lipoprotein (LDL), a type of fat in the blood. This reduces the risk of heart attack and stroke in future. It contains Rosuvastatin and Bempedoic acid. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body, which is essential to making cholesterol. Thereby, it decreases the liver's LDL (bad cholesterol) production. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood.

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Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bemzire-R 40 Tablet 1

Bemzire-R 40 Tablet 1 is used to lower the levels of bad cholesterol called low-density lipoprotein (LDL), a type of fat in the blood. This reduces the risk of heart attack and stroke in future. High cholesterol occurs when there is an excess of the unhealthy balance of cholesterol in the blood.

Bemzire-R 40 Tablet 1 is a combination of two drugs: Rosuvastatin and Bempedoic acid. Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood. 

Take Bemzire-R 40 Tablet 1 as prescribed. Your doctor will advise you how often you take Bemzire-R 40 Tablet 1 based on your medical condition. Bemzire-R 40 Tablet 1 may cause common side effects such as headache, stomach pain, dizziness, weakness, muscle pain or constipation. Most of these side effects of Bemzire-R 40 Tablet 1 do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Rosuvastatin, Bempedoic acid or any other ingredients of Bemzire-R 40 Tablet 1, please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before taking Bemzire-R 40 Tablet 1. Maintain a low-fat diet along with Bemzire-R 40 Tablet 1 for effective results.

Uses of Bemzire-R 40 Tablet 1

Bemzire-R 40 Tablet 1 is used in the treatment of High cholesterol. The detailed uses of Bemzire-R 40 Tablet 1 are as follows:<br/>• Lower LDL cholesterol: Bemzire-R 40 Tablet 1 is used to lower LDL cholesterol more effectively than either drug alone.<br/>• Reduce the risk of cardiovascular events: Bemzire-R 40 Tablet 1 is used to reduce the risk of cardiovascular events like heart attacks and strokes.<br/>

Directions for Use

• Bemzire-R 40 Tablet 1 can be taken with or without food, preferably at the same time each day.• It is usually taken once daily or as prescribed by your doctor.• Swallow Bemzire-R 40 Tablet 1 as a whole with a glass of water.• Do not break, crush, or chew it.

Medicinal Benefits

Bemzire-R 40 Tablet 1 belongs to the class of medicines called cholesterol-lowering agents. It contains Rosuvastatin, Bempedoic acid, and Ezetimibe. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood.

How Bemzire-R 40 Tablet 1 Works

Bemzire-R 40 Tablet 1 is a combination of two drugs: Rosuvastatin and Bempedoic acid. Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood.

Storage

• Store in a cool and dry place away from sunlight.• Keep Bemzire-R 40 Tablet 1 out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Bemzire-R 40 Tablet 1

Do not take more than the prescribed dose. If you take more than prescribed dose accidentally, please go to the emergency department of the closest hospital or call doctor right away. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to Rosuvastatin, Bempedoic acid or any other ingredients of Bemzire-R 40 Tablet 1, please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before taking Bemzire-R 40 Tablet 1. You are advised to take effective birth control measures to avoid pregnancy while taking Bemzire-R 40 Tablet 1. Maintain a low-fat diet along with Bemzire-R 40 Tablet 1 for effective results. If you have diabetes, inform your doctor before taking Bemzire-R 40 Tablet 1.

Drug-Drug Interactions

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RosuvastatinSaquinavir
Severe
RosuvastatinAmprenavir
Severe

Drug-Drug Interactions

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RosuvastatinSaquinavir
Severe
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Saquinavir and Bemzire-R 40 Tablet 10's can increase the blood levels of Bemzire-R 40 Tablet 10's and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Saquinavir and Bemzire-R 40 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinAmprenavir
Severe
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Bemzire-R 40 Tablet 10's and amprenavir can increase the blood levels of Bemzire-R 40 Tablet 10's and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Bemzire-R 40 Tablet 10's and Amprenavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of leflunomide and Bemzire-R 40 Tablet 10's can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Bemzire-R 40 Tablet 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Bemzire-R 40 Tablet 10's and Darunavir can increase the blood levels of Bemzire-R 40 Tablet 10's and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Bemzire-R 40 Tablet 10's and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Bemzire-R 40 Tablet 10's and Atazanavir can increase the blood levels of Bemzire-R 40 Tablet 10's and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Bemzire-R 40 Tablet 10's and Atazanavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Gemfibrozil and Bemzire-R 40 Tablet 10's may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Bemzire-R 40 Tablet 10's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Ritonavir and Bemzire-R 40 Tablet 10's can increase the blood levels of Bemzire-R 40 Tablet 10's .

How to manage the interaction:
Co-administration of Ritonavir and Bemzire-R 40 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSimeprevir
Severe
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of Simeprevir and Bemzire-R 40 Tablet 10's can increase the blood levels of Bemzire-R 40 Tablet 10's and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Simeprevir and Bemzire-R 40 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Coadministration of colchicine and Bemzire-R 40 Tablet 10's may increase the risk of conditions that affect your muscles and kidneys.

How to manage the interaction:
Taking Colchicine with Bemzire-R 40 Tablet 10's may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Bemzire-R 40 Tablet 10's :
Co-administration of ciclosporin with Bemzire-R 40 Tablet 10's can increase blood levels of Bemzire-R 40 Tablet 10's . This can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of cyclosporine and Bemzire-R 40 Tablet 10's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, light colour stools, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts, cut-down beverages, and processed and sugary foods.
  • Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight, as obesity also raises bad cholesterol and lowers good cholesterol.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS
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Alcohol

Consult your doctor

If you regularly consume alcohol, consult your doctor before taking Bemzire-R 40 Tablet 1.

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Pregnancy

Unsafe

Bemzire-R 40 Tablet 1 is not recommended to take in pregnancy. If you become pregnant while using Bemzire-R 40 Tablet 1, stop taking the medicine and inform your doctor.

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Breast Feeding

Unsafe

It is not recommended to take Bemzire-R 40 Tablet 1 during breastfeeding. Consult your doctor for more information.

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Driving

Caution

Bemzire-R 40 Tablet 1 may sometimes cause dizziness. Drive only if you are alert after taking Bemzire-R 40 Tablet 1.

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Liver

Consult your doctor

If you have liver problems, inform your doctor before taking Bemzire-R 40 Tablet 1. This medicine is not recommended in case of moderate to severe liver impairment.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Bemzire-R 40 Tablet 1. This medicine is not recommended in case of severe kidney impairment.

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Children

Consult your doctor

Safety and efficacy have not been established. Hence, please consult your doctor about using Bemzire-R 40 Tablet 1 in children.

Have a query?

FAQs

Bemzire-R 40 Tablet 1 is used to lower the levels of bad cholesterol called low-density lipoprotein (LDL), a type of fat in the blood. This reduces the risk of heart attack and stroke in future.

Bemzire-R 40 Tablet 1 works by decreasing the production of LDL (bad cholesterol) by the liver and increases the removal of LDL cholesterol from the blood. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.

Bemzire-R 40 Tablet 1 should be used in diabetic patients only if the doctor advises, as it may increase blood sugar levels. Regular monitoring of blood sugar levels is recommended in diabetic patients, and inform your doctor before taking Bemzire-R 40 Tablet 1 if you are diabetic.

You are not recommended to stop taking Bemzire-R 40 Tablet 1 without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Bemzire-R 40 Tablet 1 for as long as your doctor has prescribed it, and if you experience any difficulty while taking Bemzire-R 40 Tablet 1, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - BEM0033

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