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compositionComposition:BEMPEDOIC ACID-180MG
prescription
Prescription Medicine
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Bemdac 180 Tab is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BEMPEDOIC ACID-180MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bemdac 180 Tab

Bemdac 180 Tab is a tablet used to lower low-density lipoprotein (LDL) cholesterol, often referred to as 'bad' cholesterol, in the blood. It is prescribed for adults who need additional help lowering their cholesterol, particularly those with inherited high cholesterol or established heart disease. By lowering bad cholesterol, this medication helps reduce the risk of cardiovascular complications.

You should take Bemdac 180 Tab consistently once every day, exactly as directed by your doctor. This oral tablet can be taken with or without food at any time of the day. To achieve the best results, it is important to continue with a heart-healthy diet and regular physical activity.

While taking Bemdac 180 Tab , some people may experience mild side effects like muscle spasms, back pain, or pain in the arms or legs. However, you should consult your doctor immediately if you experience severe joint pain or signs of a tendon injury, as these can be serious.

Do not take this if you are pregnant, planning to become pregnant, or breastfeeding, as it may harm the unborn baby or infant. Before starting Bemdac 180 Tab , talk to your doctor if you have ever had gout, severe kidney problems, or liver damage.

This medicine can interact with certain other cholesterol-lowering drugs, specifically high doses of simvastatin or pravastatin, which can increase the risk of muscle injury. Talk to your doctor or pharmacist about safe levels of alcohol, as both alcohol and this medicine can affect your liver. Elderly patients and those taking other prescription drugs should seek specific guidance to ensure safe use.

Uses of Bemdac 180 Tab

Your doctor may prescribe Bemdac 180 Tab to treat the following conditions to help lower cholesterol levels, reduce the risk of cardiovascular complications, and improve heart health:

  • High cholesterol (Hypercholesterolemia): Bemdac 180 Tab helps lower high levels of low-density lipoprotein (LDL-C) in the blood when diet and maximum-dose statin therapy are not enough.
  • Heterozygous familial hypercholesterolemia (HeFH): This is an inherited condition that causes dangerously high cholesterol levels; Bemdac 180 Tab helps by further reducing bad cholesterol in these individuals.
  • Atherosclerotic cardiovascular disease (ASCVD): For patients with established heart or blood vessel disease, Bemdac 180 Tab helps lower cholesterol to target levels to prevent further cardiovascular events.

Key Benefits

Using Bemdac 180 Tab as prescribed helps lower LDL (bad) cholesterol, support heart health, and reduce the risk of cardiovascular complications. Here are the key benefits you can expect:

  • Effectively lowers LDL cholesterol: Helps reduce high LDL (bad) cholesterol levels, especially when diet, lifestyle changes, and statin therapy alone are not enough.
  • Supports cardiovascular health: By lowering cholesterol production in the liver, it helps reduce the risk of future heart attacks, strokes, and other cardiovascular events.
  • Provides a convenient treatment option: Offers a once-daily oral tablet that can be used as an alternative or add-on treatment for people who cannot tolerate high doses of other cholesterol-lowering medicines due to muscle-related side effects.
Side effects of Bemdac 180 mg Tablet
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Bemdac 180 Tab can be taken with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication for effective results.
  • Swallow Bemdac 180 Tab as a whole with water.
  • Do not crush, chew, or break it.

How Bemdac 180 Tab Works

Bemdac 180 Tab contains bempedoic acid, a cholesterol-lowering medicine that works by blocking an enzyme in the liver called adenosine triphosphate-citrate lyase (ACL). This enzyme plays an important role in the body's cholesterol production process. By blocking ACL, Bemdac 180 Tab reduces the amount of cholesterol produced by the liver. In response, the liver removes more low-density lipoprotein (LDL), also known as 'bad' cholesterol, from the bloodstream. This helps lower LDL cholesterol levels and supports better cardiovascular health.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Bemdac 180 Tab . Please consult a doctor.

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Pregnancy

Unsafe

Bemdac 180 Tab may harm the unborn baby. Do not take Bemdac 180 Tab if you are pregnant, think you may be pregnant or if you are trying to become pregnant. Consult the doctor immediately if you become pregnant during treatment with Bemdac 180 Tab .

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Breast Feeding

Unsafe

It is unknown if Bempedoic acid passes into breast milk. Do not take Bemdac 180 Tab if you are breastfeeding.

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Driving

Safe if prescribed

Bemdac 180 Tab has little or no influence on your ability to drive.

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Liver

Consult your doctor

It is not known if Bemdac 180 Tab is safe and effective in people with liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

It is not known if Bemdac 180 Tab is safe and effective in people with kidney disease, including end-stage kidney disease, who are on dialysis. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Bemdac 180 Tab is not recommended for children below 18 years as the safety and effectiveness have not been established.

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Heart

Caution

Take Bemdac 180 Tab with caution, especially if you have a history of heart disease. Inform your doctor before receiving the Bemdac 180 Tab if you have a history of heart diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Bemdac 180 Tab can be used in the elderly when prescribed by a doctor. If you have any concerns about using Bemdac 180 Tab , please consult a doctor.

What if I have taken an overdose of Bemdac 180 Tab

If you accidentally take too much of this medicine, seek immediate medical attention. Bring the medication package with you so the healthcare providers know exactly what you took.

Diet & Lifestyle Advise

  • Follow a heart-healthy diet: Eat foods rich in soluble fibre, such as oats, beans, lentils, and fresh fruits, to help lower cholesterol absorption.
  • Limit unhealthy fats: Reduce your intake of saturated fats and avoid trans fats found in fried and processed foods, as they can increase LDL ('bad') cholesterol levels.
  • Maintain a healthy lifestyle: Aim for at least 150 minutes of moderate-intensity aerobic exercise, such as brisk walking or cycling, each week to support healthy cholesterol levels.
  • Stay well hydrated: Drink enough water throughout the day to support your overall health. (Maintaining hydration is beneficial, although it is not specifically related to the cholesterol-lowering effects of Bemdac 180 Tab .)
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How Soon It Starts Working

  • The time required for Bemdac 180 Tab to start to work: Bemdac 180 Tab ideally shows its action within 3.5 hours after administration.
  • The time for which the effects of Bemdac 180 Tab last: The effect of Bemdac 180 Tab lasts for 15 to 24 hours.

What if you forget to take Bemdac 180 Tab

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Bemdac 180 Tab at 20°C to 25°C (68°F to 77°F) in its original packaging to protect it from moisture and light.

Drug Warnings

  • Monitor your joints closely: This medicine can raise uric acid levels, which may cause gout. Report any sudden joint pain, swelling, or redness to your doctor immediately.
  • Be alert for tendon issues: There is a small risk of tendon rupture or injury while taking this medicine. Avoid strenuous physical activity if you feel sudden pain in your tendons.
  • Keep track of your blood work: Your doctor will likely schedule routine blood tests to check your liver function and uric acid levels. Make sure to attend all appointments.
  • Check compatibility before starting new drugs: Always inform any healthcare provider that you are taking Bemdac 180 Tab before starting any new prescription or over-the-counter medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Simvastatin and Pravastatin (cholesterol medications): Combining these with Bemdac 180 Tab can significantly increase the levels of these statins in your blood, raising the risk of muscle pain and weakness.
Bempedoic acidCiprofloxacin
Severe
Bempedoic acidEnoxacin
Severe

Drug-Drug Interactions

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Bempedoic acidCiprofloxacin
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Taking Bemdac 180 mg Tablet with Ciprofloxacin may can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Ciprofloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints, consult a doctor immediately. Exercise and using the affected area should be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidEnoxacin
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Bemdac 180 mg Tablet and enoxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Enoxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidNalidixic acid
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Bemdac 180 mg Tablet and nalidixic acid can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Nalidixic acid if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bemdac 180 mg Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidPrednisolone
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Bemdac 180 mg Tablet and Prednisolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Prednisolone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bemdac 180 mg Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidBetamethasone
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Betamethasone with Bemdac 180 mg Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Betamethasone with Bemdac 180 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience pain, swelling, or inflammation in joints consult a doctor immediately. Exercising or using the injured area should also be avoided. Do not discontinue the medications without a doctor's advice.
Bempedoic acidTriamcinolone
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Taking Bemdac 180 mg Tablet with Triamcinolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction between Bemdac 180 mg Tablet and triamcinolone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bemdac 180 mg Tablet and consult a doctor. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGatifloxacin
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Bemdac 180 mg Tablet and gatifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor immediately. Avoid or limit exercising or using the impacted area. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGrepafloxacin
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Bemdac 180 mg Tablet and Grepafloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Grepafloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidFludrocortisone
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Taking Bemdac 180 mg Tablet with Fludrocortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Fludrocortisone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation in joints, consult a doctor. Exercising or using the injured area should also be avoided Do not discontinue any medications without consulting a doctor.
Bempedoic acidGemifloxacin
Severe
How does the drug interact with Bemdac 180 mg Tablet:
Co-administration of Bemdac 180 mg Tablet and Gemifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bemdac 180 mg Tablet can be taken with Gemifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Bemdac 180 Tab when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Bemdac 180 Tab is used to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).
Bemdac 180 Tab works by blocking the production of cholesterol in the liver. Thereby, it helps treat high cholesterol.
Do not discontinue Bemdac 180 Tab without consulting your doctor, as it could lead to a rise in cholesterol. To get effective results, continue taking Bemdac 180 Tab for as long as prescribed. Do not hesitate to speak with your doctor if you experience any difficulty while taking Bemdac 180 Tab .
Tendon problems may happen in people taking Bemdac 180 Tab . Consult the doctor if you experience pain, swelling, inflammation and tears of tendons, including Achilles (back of ankle), arm and shoulder. The risk of tendon problems may be increased if you are above 60 years of age, have renal problems, have had tendon problems or are taking antibiotics or corticosteroids.
Bemdac 180 Tab can sometimes affect the liver. While it's generally safe, some people may have slightly elevated liver enzymes. These usually go back to normal on their own. If you notice any signs of liver problems, like yellowing of the skin or dark urine, talk to your doctor right away.
Your doctor may not prescribe Bemdac 180 Tab if you have a history of tendon problems, severe liver problems, or if you're pregnant or breastfeeding. It can also interact with certain other medications. If you have any of these conditions, talk to your doctor before starting Bemdac 180 Tab .
Take it with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.
LDL cholesterol is often called "bad cholesterol" because it can clog your arteries. This can make it harder for blood to reach your heart, increasing your risk of heart problems.
HDL cholesterol is often called "good cholesterol" because it helps clear out bad cholesterol. Higher levels of HDL can be good for your heart health. But it's important to manage both good and bad cholesterol for a healthy heart.
The only way to know whether you have high cholesterol is to get your cholesterol checked. Your health professional can do a simple blood test. This is called a lipid profile.
A healthy level of total cholesterol is below 5mmol/L. HDL (good cholesterol) is above 1.0mmol/L for men or above 1.2mmol/L for women. non-HDL (bad cholesterol) is below 4mmol/L.
High cholesterol can increase your risk of heart problems. It can build up in your arteries and cause problems like heart attacks. If you have symptoms like chest pain, shortness of breath, or fatigue, see a doctor. They can check your cholesterol and recommend treatment.
Lifestyle changes can help Bemdac 180 Tab work better. Eat healthy, exercise regularly, maintain a healthy weight, quit smoking, limit alcohol, and manage stress. These changes can help lower your cholesterol and reduce your risk of heart problems.
While Bemdac 180 Tab is generally well-tolerated, some people may experience side effects such as muscle pain, joint pain, fatigue, or digestive issues. If you experience any adverse effects, talk to your doctor.
Yes, Bemdac 180 Tab is generally safe for people with diabetes. However, it's important to monitor your blood sugar levels closely while taking this medication.
If you have mild to moderate kidney problems, you may still be able to take Bemdac 180 Tab . However, it's important to discuss this with your doctor, as your dosage may need to be adjusted.
No, Bemdac 180 Tab is not known to cause weight gain.
Yes, Bemdac 180 Tab can be taken with other cholesterol-lowering medications if prescribed by the doctor.
High cholesterol can be caused by many things, including age, family history, diet, lack of exercise, smoking, being overweight, and having conditions like diabetes or thyroid problems.
It depends on how risky you are of having heart problems. If you have a lot of things that can increase your risk, you might need to check it more often.
Yes, Bemdac 180 Tab is often prescribed for people who experience muscle pain or other side effects from statins. It works differently than statins to lower cholesterol. Talk to your doctor to see if this is the right option for you.
There are no specific food restrictions or major drug-food interactions associated with Bemdac 180 Tab . However, it is highly recommended to follow a cholesterol-lowering, low-fat diet to get the maximum benefit from your treatment. Talk to your doctor for personalised dietary advice.
While muscle spasms can occur, Bemdac 180 Tab does not typically cause the same high rate of muscle pain as statins because of how it is processed in the body. If you develop unexplained muscle pain, weakness, or tenderness, talk to your doctor.
No, you should not take Bemdac 180 Tab if you are pregnant or planning to become pregnant, as it may harm your developing baby. If you become pregnant while taking this medication, stop taking it and talk to your doctor immediately.
Moderate alcohol consumption is generally acceptable, but excessive drinking can increase the risk of liver strain when combined with cholesterol medications. Talk to your doctor or pharmacist about safe levels of alcohol intake for you.
This medicine can increase the levels of uric acid in your blood, which can sometimes lead to gout, a type of painful joint inflammation. If you have a history of gout or experience sudden joint pain, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.11743 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 211616S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A620020 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Bempedoic Acid [Product Information]. 2024. [Accessed on 05 Mar. 2025]Check here
  5. Daiichi Sankyo UK Limited. Nilemdo 180 mg film‑coated tablets: Summary of Product Characteristics [Internet]. UK: Datapharm Ltd.; last updated 07 Jul 2025 [Accessed on 2025 Dec 30]Check here
  6. Elani Streja, Dan A. Streja. Management of Dyslipidemia in the Elderly. NIH National Library of Medicine. National Center for Biotechnology Information. Endotext [Internet]. September 2020. [Accessed on 4th August 2022]Check here
  7. Central Drugs Standard Control Organization (CDSCO). Drugs: Approved Drugs / Vaccines / r-DNA / Blood Products [Internet]. Government of India; [Accessed on 2025 Dec 30]Check here

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad 380015 Gujarat, India.
Other Info - BEM0021
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