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  3. Bdrelin Depot 3.75 Combipack Injection 1's

Bdrelin Depot 3.75 Combipack Injection 1's, Pack of 1 Respules
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Bdrelin Depot 3.75 Combipack Injection is used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. It contains Triptorelin which works by inhibiting the synthesis of testosterone in men and oestrogen in women. In some cases, this medicine may cause side effects such as hot flashes, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in the legs. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

TRIPTORELIN-3.75MG

Manufacturer/Marketer :

BDR Pharmaceuticals Internationals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Bdrelin Depot 3.75 Combipack Injection

Bdrelin Depot 3.75 Combipack Injection belongs to the class of 'anti-neoplastic agents', primarily used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Bdrelin Depot 3.75 Combipack Injection contains Triptorelin that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. The lowering of testosterone hormone levels in men helps slows down the growth of cancer cells in prostate cancer.

Use Bdrelin Depot 3.75 Combipack Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Bdrelin Depot 3.75 Combipack Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, flu symptoms, nausea, vomiting, diarrhoea, upset stomach and swelling in legs. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Bdrelin Depot 3.75 Combipack Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Bdrelin Depot 3.75 Combipack Injection is not indicated for use in pregnant and breastfeeding women. Bdrelin Depot 3.75 Combipack Injection may make you feel dizzy, hence drive when you are alert only. Bdrelin Depot 3.75 Combipack Injection is not recommended for children below two years of age.

Uses of Bdrelin Depot 3.75 Combipack Injection

Treatment of Prostate cancer, endometriosis and precocious puberty.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Bdrelin Depot 3.75 Combipack Injection will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Bdrelin Depot 3.75 Combipack Injection contains Triptorelin, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Bdrelin Depot 3.75 Combipack Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Bdrelin Depot 3.75 Combipack Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Bdrelin Depot 3.75 Combipack Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis. Bdrelin Depot 3.75 Combipack Injection also has the role of a contraceptive drug.

How Bdrelin Depot 3.75 Combipack Injection Works

Bdrelin Depot 3.75 Combipack Injection contains Triptorelin that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. The lowering of testosterone hormone levels in men helps slows down the growth of cancer cells in prostate cancer.

Storage

Keep out of sight and reach of children.
Side effects of Bdrelin Depot 3.75 Combipack Injection
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.
  • Rest well; get enough sleep. This helps the body fight infection.
  • Keep yourself hydrated by drinking enough water and other fluids.
  • Wash your hands often and avoid touching your eyes, mouth or nose.
  • Wear a mask whilst going out.
  • Warm steam or a hot shower may help with nose secretions.
  • Avoid contact with others to prevent contamination.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Boost immunity with vitamins by including foods rich in vitamins C (citrus fruits, bell peppers) and D (fortified milk, fatty fish).
  • Eat omega-3 rich foods like fatty fish like salmon, tuna, and sardines to reduce inflammation.
  • Stay hydrated by drinking plenty of fluids to thin mucus and aid drainage.
  • Consider probiotic-rich foods like yogurt to potentially help prevent future ear infections.
  • Limit dairy and sugar intake to manage mucus production.
  • Sleep with head elevated by using extra pillows to facilitate fluid drainage.
  • Apply warm compress for temporary pain relief.
  • Wash hands frequently to prevent spreading germs.
  • Use a humidifier to add moisture to the air to help with congestion and ear pressure.
  • Avoid secondhand smoke to reduce risk of ear infections.
  • Consult your doctor before making significant dietary or lifestyle changes, especially if taking medication for ear infection.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Bdrelin Depot 3.75 Combipack Injection

Since Bdrelin Depot 3.75 Combipack Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Inform your doctor if you have any allergic reactions to Bdrelin Depot 3.75 Combipack Injection or other medications. Before starting Bdrelin Depot 3.75 Combipack Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Bdrelin Depot 3.75 Combipack Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Bdrelin Depot 3.75 Combipack Injection. Bdrelin Depot 3.75 Combipack Injection can affect the unborn baby when used in pregnancy. Hence, Bdrelin Depot 3.75 Combipack Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Bdrelin Depot 3.75 Combipack Injection, make sure to use reliable forms of contraception to prevent pregnancy during the course. Bdrelin Depot 3.75 Combipack Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Bdrelin Depot 3.75 Combipack Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Bdrelin Depot 3.75 Combipack Injection is not recommended for children younger than two years of age.

Drug-Drug Interactions

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TriptorelinClozapine
Severe
TriptorelinMoxifloxacin
Severe

Drug-Drug Interactions

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TriptorelinClozapine
Severe
How does the drug interact with Bdrelin Depot 3.75 Combipack Injection:
Combining Bdrelin Depot 3.75 Combipack Injection with Clozapine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Bdrelin Depot 3.75 Combipack Injection and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like an irregular heart rhythm, dizziness, shortness of breath, or heart palpitations, it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
TriptorelinMoxifloxacin
Severe
How does the drug interact with Bdrelin Depot 3.75 Combipack Injection:
Using moxifloxacin together with Bdrelin Depot 3.75 Combipack Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Bdrelin Depot 3.75 Combipack Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like an irregular heart rhythm, prolonged diarrhea or vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, you should contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TriptorelinCeritinib
Severe
How does the drug interact with Bdrelin Depot 3.75 Combipack Injection:
Coadministration of Bdrelin Depot 3.75 Combipack Injection with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Ceritinib with Bdrelin Depot 3.75 Combipack Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Habit Forming

No

Therapeutic Class

GONADOTROPHIN-RELEASING HORMONE AGONIST

Bdrelin Depot 3.75 Combipack Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is advised to avoid alcohol consumption to minimize the unwanted effects of Bdrelin Depot 3.75 Combipack Injection. Please consult your doctor for more information.

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Pregnancy

Unsafe

Bdrelin Depot 3.75 Combipack Injection is a pregnancy category X drug. It is unsafe to use Bdrelin Depot 3.75 Combipack Injection in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Bdrelin Depot 3.75 Combipack Injection.

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Breast Feeding

Unsafe

Bdrelin Depot 3.75 Combipack Injection is unsafe to use during breastfeeding. Consult your doctor for further information.

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Driving

Unsafe

Bdrelin Depot 3.75 Combipack Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Bdrelin Depot 3.75 Combipack Injection.

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment before starting Bdrelin Depot 3.75 Combipack Injection.

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting Bdrelin Depot 3.75 Combipack Injection.

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Children

Caution

Bdrelin Depot 3.75 Combipack Injection is not recommended in children younger than two years of age.

Have a query?

FAQs

Bdrelin Depot 3.75 Combipack Injection is used to treat prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children.

Bdrelin Depot 3.75 Combipack Injection contains Triptorelin, a synthetic hormone. It helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis in women.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Bdrelin Depot 3.75 Combipack Injection should be used with caution and under doctor's supervision only if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Let your doctor know if you have any other medical concerns before using Bdrelin Depot 3.75 Combipack Injection.

During treatment with Bdrelin Depot 3.75 Combipack Injection in the first few weeks, a temporary increase in hormones may occur before they decrease. This may cause new or worsening of side effects of Bdrelin Depot 3.75 Combipack Injection. This is a normal response of your body to Bdrelin Depot 3.75 Combipack Injection. However, if you notice any symptoms that are not manageable, please seek medical advice.

Bdrelin Depot 3.75 Combipack Injection may worsen your mood disorders like depression. Hence it is advised to use Bdrelin Depot 3.75 Combipack Injection only when you are free from any kind of mental problems. Please consult your doctor for more information.

Bdrelin Depot 3.75 Combipack Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Bdrelin Depot 3.75 Combipack Injection.

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - BDR0007

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:49 AM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-22363-9162/triptorelin-pamoate-intramuscular/triptorelin-1-month-3-75-mg-injection/details
  2. https://www.medicines.org.uk/emc/files/pil.780.pdf
  3. https://www.drugs.com/mtm/triptorelin.html#uses
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