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Baxter Aerrane belongs to the class of medications called inhalation anaesthetics. It contains isoflurane used to induce and maintain general anesthesia during surgical procedures. In some individuals, Baxter Aerrane may cause side effects like nausea, vomiting, dizziness, drowsiness, and weakness. Inform your doctor, if you are pregnant or breastfeeding, about your health condition and medications before receiving Baxter Aerrane .

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Written By Thota sri Harshini ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ISOFLURANE-400MG

Manufacturer/Marketer :

Baxter India Pvt Ltd

Consume Type :

Inhalation

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Baxter Aerrane

Baxter Aerrane is an inhalation medicine used to induce and maintain general anaesthesia. It is used to keep patients in a deep, pain-free sleep during various types of surgical procedures. This medicine helps ensure that you do not feel pain or remember the surgery while it is being performed.

This medicine is not for regular daily use and is given only by a healthcare professional in a hospital or surgical setting when you undergo a procedure. Before receiving this medicine, patients are typically required to fast, meaning they must not eat or drink anything for a set period. Following preoperative fasting guidelines is crucial for your safety during the procedure.

Common side effects of this medicine include temporary shivering, nausea, and vomiting as you wake up. If you experience severe muscle stiffness, a very high fever, or breathing difficulties after the procedure, you must alert your medical team immediately.

Do not take this if you or your family members have a history of a rare, severe reaction to anaesthesia called malignant hyperthermia. It is also important to tell your doctor if you have heart disease, liver damage, or neuromuscular disorders before undergoing anaesthesia.

This medicine can interact with other drugs like muscle relaxants and blood pressure medications, which may require your healthcare provider to adjust your doses. It is also vital to inform your medical team if you are pregnant, breastfeeding, or if the patient is an elderly individual, as special precautions may be needed. Talk to your doctor or pharmacist to discuss your specific medical history.

Description

Baxter Aerrane is an inhalation-type anaesthetic. It is a volatile halogenated anaesthetic used for general inhalation anaesthesia.

Uses of Baxter Aerrane

Your doctor or anaesthesiologist may use Baxter Aerrane for the following purposes:

  • General anaesthesia induction: Helps transition patients into a deep, unconscious state before a surgical procedure begins.
  • General anaesthesia maintenance: Keeps patients asleep and completely free of pain during the entire duration of the surgery.

 

Key Benefits

Using Baxter Aerrane as directed by your anaesthesiologist provides safe and effective anaesthesia during surgical procedures. Here are the key benefits you can expect:

  • Enables pain-free surgery: Baxter Aerrane produces a controlled state of unconsciousness, allowing surgical and medical procedures to be performed without pain or awareness.
  • Provides controlled anaesthesia: The depth of anaesthesia can be adjusted throughout the procedure to meet the patient's needs and maintain comfort and safety.
  • Supports a smooth recovery: Once the administration of Baxter Aerrane is stopped, patients generally regain consciousness in a predictable manner under close medical supervision.
Side effects of Baxter Aerrane 250ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • To assist warm the body, sip herbal teas like peppermint or ginger.
  • To provide warmth to the body, use heating pads or hot water bottles.
  • Avoid lying or sitting on chilled surfaces as this can make shivering worse.
  • To increase body temperature, take warm showers or baths.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Baxter Aerrane will be given by a doctor or nurse in a medical facility, and you will breathe it in through a mask over your mouth and nose.
  • Do not self-administer.

How Baxter Aerrane Works

Baxter Aerrane contains isoflurane, a volatile inhalational general anaesthetic that is administered as a vapour through a breathing mask or breathing tube. After inhalation, Baxter Aerrane is rapidly absorbed through the lungs into the bloodstream and reaches the brain, where it temporarily reduces the activity of the central nervous system. By enhancing inhibitory nerve signals and suppressing excitatory nerve activity in the brain and spinal cord, Baxter Aerrane produces a reversible state of unconsciousness, loss of sensation, and muscle relaxation. This allows surgical procedures to be performed without pain or awareness while the anaesthesiologist carefully monitors and adjusts the depth of anaesthesia throughout the operation.
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Alcohol

Unsafe

Avoid/limit alcohol consumption as it may increase the metabolism of isoflurane and plasma levels.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Baxter Aerrane . It should only be used in pregnant women if the benefit outweighs the potential risk.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Baxter Aerrane . Caution should be exercised when Baxter Aerrane is administered to the nursing women.

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Driving

Unsafe

Baxter Aerrane may affect mental alertness. Therefore, do not drive or operate machinery for at least 24 hours after administering a general anaesthetic.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Baxter Aerrane . Your doctor will examine your liver condition and determine if it's safe for you to receive this medication.

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Kidney

Caution

Inform your doctor before receiving Baxter Aerrane if you have any kidney diseases. The doctor will administer the medicine if the benefits outweigh the risks.

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Children

Consult your doctor

Baxter Aerrane should be used cautiously in children and only if advised by the doctor.

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Heart

Caution

Inform your doctor before receiving Baxter Aerrane if you have any heart diseases. The doctor will administer the medicine if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Baxter Aerrane in elderly patients.

What if I have taken an overdose of Baxter Aerrane

An overdose is highly unlikely because a trained anesthesiologist constantly monitors you while you receive this medicine. However, if an issue occurs, the medical team will immediately adjust or stop the inhalation and provide supportive care.

Diet & Lifestyle Advise

  • Fast before surgery: Strictly follow instructions to not eat or drink (usually for at least 6 to 8 hours) before your scheduled procedure to prevent vomiting and lung complications.
  • Avoid alcohol and sedatives: Do not consume alcohol or take any calming medicines for at least 24 hours after your surgery, as they can dangerously increase drowsiness.
  • Arrange for a ride home: You must have a responsible adult drive you home after your procedure, as your reaction times and judgment will be temporarily impaired.
  • Rest and eat lightly: Keep your meals light and easy to digest (such as plain toast or broth) for the first 24 hours after waking up to minimize stomach upset.
health query

Have a query?

How Soon It Starts Working

The time required for Baxter Aerrane to start to work: The effect of Baxter Aerrane can be seen in 7-10 minutes of administration. The time for which the effects of Baxter Aerrane last: The duration of Baxter Aerrane effectiveness can vary based on the dosage taken.

What if you forget to take Baxter Aerrane

Since this medicine is given only by a healthcare professional during a planned medical procedure, it is not possible for you to miss a dose.

Storage

• This medicine is stored in clinical environments at controlled room temperature, between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Inform your anaesthesiologist about previous reactions: Tell your medical team if you or any close family member has ever experienced a serious reaction to general anaesthesia, including malignant hyperthermia or other anaesthetic complications.
  • Avoid driving or operating machinery: Do not drive, operate heavy machinery, or sign important legal documents for at least 24 hours after receiving Baxter Aerrane , or until your doctor advises that it is safe.
  • Provide a complete medication history: Inform your doctor about all prescription medicines, over-the-counter medicines, vitamins, herbal products, and supplements you are taking before your procedure.
  • Avoid smoking before surgery: Stop smoking as early as possible before your operation, as smoking can affect lung function and increase the risk of breathing complications during and after anaesthesia.

Drug-Drug Interactions

verifiedApollotooltip
  • Muscle relaxants: Baxter Aerrane may enhance the effects of muscle relaxants, so lower doses may be needed during surgery.
  • Blood pressure medicines: Taking Baxter Aerrane with antihypertensive medicines may increase the risk of a temporary drop in blood pressure during anaesthesia.
  • Epinephrine and other sympathomimetic medicines: These medicines may increase the risk of irregular heart rhythms when used with Baxter Aerrane .
IsofluraneZiprasidone
Critical
IsofluraneTirzepatide
Severe

Drug-Drug Interactions

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IsofluraneZiprasidone
Critical
How does the drug interact with Baxter Aerrane 250ml:
Taking Baxter Aerrane 250ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Baxter Aerrane 250ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
IsofluraneTirzepatide
Severe
How does the drug interact with Baxter Aerrane 250ml:
Tirzepatide may cause the stomach to take longer to empty, which raises the possibility of vomiting during anesthesia and the inhalation of stomach contents into the lungs.

How to manage the interaction:
Before undergoing surgery or a procedure, inform doctor if on tirzepatide treatment. Doctor may temporarily stop the treatment or take further precautions to reduce the risks.
IsofluranePhenylephrine
Severe
How does the drug interact with Baxter Aerrane 250ml:
Taking Phenylephrine with Baxter Aerrane 250ml may lead to increased side effects of Phenylephrine.

How to manage the interaction:
Co-administration of Phenylephrine with Baxter Aerrane 250ml can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
IsofluraneSelegiline
Severe
How does the drug interact with Baxter Aerrane 250ml:
Co-administration of Baxter Aerrane 250ml and Selegiline can lead to fluctuations in blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Selegiline and Baxter Aerrane 250ml, but it can be taken if prescribed by a doctor. In case you experience symptoms like lightheadedness, confusion, fits, palpitations, fainting or blurred vision, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Baxter Aerrane when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[INHALATIONAL ANESTHETICS]

FAQs

Baxter Aerrane is used for general anaesthesia induction and maintenance during surgical procedures.
Baxter Aerrane contains isoflurane, which works by affecting various receptors and ion channels in the central nervous system to produce anaesthesia. Thereby, it helps to induce unconsciousness suitable for surgical procedures without causing any pain for the patient.
Baxter Aerrane is administered by inhalation and delivered from a vaporizer designed explicitly for Baxter Aerrane .
The side effects of Baxter Aerrane are chills/shivering, cough, laryngospasm (difficulty breathing or speaking), nausea, and vomiting. Consult your doctor if the side effects persist or worsen.
No, Baxter Aerrane is not recommended for self-administration. It should be administered in a hospital setting only by persons trained in the administration of general anaesthesia.
No, you must not drive or operate machinery for at least 24 hours after receiving this medicine, as it temporarily affects your coordination and judgment. Talk to your doctor about planning a safe ride home.
Fasting helps prevent stomach contents from entering your lungs while you are asleep, which is a serious safety risk. Talk to your doctor or pharmacist about fasting guidelines.
The most common side effects include shivering, nausea, vomiting, and a temporary drop in blood pressure as you wake up. Talk to your doctor if you are concerned about side effects.
In very rare cases, inhaled anaesthetics can lead to liver damage. Let your doctor know if you have any pre-existing liver conditions before surgery. Talk to your doctor for more information.
It should only be used during pregnancy if the potential benefits outweigh the risks, and under strict medical supervision. Talk to your doctor if you are pregnant or breastfeeding.

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Author Details

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Country of origin

India

Manufacturer/Marketer address

Baxter (India) Private Limited, 2nd Floor, Tower-C, Building No.8, DLF Cyber City, DLF Phase-II, Gurgaon-122 002, Haryana, India
Other Info - AER0014
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