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  3. Bardep Plus Tablet 10's

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Bardep Plus Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Bardep Plus Tablet is used to treat depression. It contains Alprazolam and Fluoxetine which improve mood and suppress the abnormal activity of the nerve cells in the brain. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, confusion, drowsiness, tiredness, and low sexual desire. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ALPRAZOLAM-0.25MG + FLUOXETINE-20MG

Manufacturer/Marketer :

Biologic Psychotropics India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bardep Plus Tablet

Bardep Plus Tablet belongs to the class of medications called ‘antidepressants' primarily used for the treatment of depression, which is a mood disorder that causes a persistent feeling of sadness and loss of interest. Depression is also called a major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to various emotional and physical problems.

Bardep Plus Tablet contains a combination of two medicines called alprazolam and fluoxetine. Alprazolam is a benzodiazepine (BZD) that increases the action of GABA (gamma-aminobutyric acid), a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels, a chemical messenger that improves mood.

Take this Bardep Plus Tablet in the dose and duration as advised by your doctor. Swallow it as a whole with a glass of water. Do not chew, crush or break it. Bardep Plus Tablet may be taken with or without food, but it is better to take it at a fixed time. Bardep Plus Tablet may cause common side effects like nausea, vomiting, diarrhoea, confusion, memory impairment, drowsiness, tiredness, low sexual desire, and uncoordinated body movements. These side effects do not require any medical attention and resolve on their own. If any of these effects persist, contact your doctor immediately.

If you are known to be allergic to Bardep Plus Tablet or any other medicines, please tell your doctor. Do not take Bardep Plus Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Inform your doctor if you have liver or kidney problems, closed-angle glaucoma, cardiac diseases, bleeding disorders, epilepsy and electro-convulsive therapy before taking Bardep Plus Tablet . Also, inform your doctor about diabetes and pulmonary insufficiency before taking Bardep Plus Tablet .

Uses of Bardep Plus Tablet

Treatment of Depression.

Directions for Use

• Bardep Plus Tablet can be taken with or without food, but it is better to take it at a fixed time.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Bardep Plus Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Bardep Plus Tablet contains a combination of two medicines called alprazolam and fluoxetine belongs to the class of medications called antidepressants, primarily used for the treatment of depression. Alprazolam is a benzodiazepine (BZD) that increases the action of GABA (gamma-aminobutyric acid), a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels, a chemical messenger that improves mood.

How Bardep Plus Tablet Works

Bardep Plus Tablet contains a combination of two medicines called alprazolam and fluoxetine. Alprazolam is a benzodiazepine (BZD) that increases the action of GABA (gamma-aminobutyric acid), a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels, a chemical messenger that improves mood.

Storage

stored at room temperature below 30°C
Side effects of Bardep Plus Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Identify the medicine causing abnormal movements and discuss with your doctor about change in dose or alternative medicine.
  • Record the frequency and severity of your abnormal movements to discuss with your doctor.
  • If you experience worsening of your movements, contact your doctor immediately.
  • Based on the severity and type of movement disturbance, your doctor may recommend physical therapy.

What if I have taken an overdose of Bardep Plus Tablet

Take Bardep Plus Tablet only as prescribed by the doctor. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Bardep Plus Tablet or any other medicines, please tell your doctor. Do not take Bardep Plus Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Inform your doctor if you have liver or kidney problems, closed-angle glaucoma, cardiac diseases, bleeding disorders, epilepsy, and electro-convulsive therapy before taking Bardep Plus Tablet . Also, inform your doctor if you have diabetes and pulmonary insufficiency before taking Bardep Plus Tablet . Inform your doctor if you have a history of depression or any other mental disorder or have been hospitalized for mental illnesses or drug or alcohol addiction before taking Bardep Plus Tablet .

Drug-Drug Interactions

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AlprazolamSodium oxybate
Critical
AlprazolamIndinavir
Critical

Drug-Drug Interactions

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AlprazolamSodium oxybate
Critical
How does the drug interact with Bardep Plus Tablet:
Co-administration of Bardep Plus Tablet with Sodium Oxybate may increase Sodium Oxybate's adverse effects (respiratory depression, low blood pressure, fainting).

How to manage the interaction:
Although the combination of Bardep Plus Tablet and sodium oxybate may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: breathing difficulties, low blood pressure, being severely drowsy, or fainting. Avoid driving or operating hazardous machinery or performing other hazardous activities for at least 6 hours after taking a dose. Do not discontinue any medications without consulting a doctor.
AlprazolamIndinavir
Critical
How does the drug interact with Bardep Plus Tablet:
The combination of Bardep Plus Tablet and Indinavir may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Bardep Plus Tablet and Indinavir, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamCeritinib
Critical
How does the drug interact with Bardep Plus Tablet:
Co-administration of Bardep Plus Tablet with Ceritinib may considerably increase the blood levels and effects of Bardep Plus Tablet.

How to manage the interaction:
Although there is a interaction between Bardep Plus Tablet and Ceritinib, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamItraconazole
Critical
How does the drug interact with Bardep Plus Tablet:
Bardep Plus Tablet's blood levels may be significantly raised when combined with itraconazole.

How to manage the interaction:
Although combining Bardep Plus Tablet and Itraconazole may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
AlprazolamDelavirdine
Critical
How does the drug interact with Bardep Plus Tablet:
The combination of Bardep Plus Tablet and Delavirdine may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Bardep Plus Tablet and Delavirdine, it can be used if prescribed by a doctor. Consult a doctor if you have sleepiness, dizziness, confusion, or weak or rapid breathing over a long duration of time. Do not discontinue any medications without consulting a doctor.
AlprazolamClarithromycin
Critical
How does the drug interact with Bardep Plus Tablet:
The combination of Bardep Plus Tablet and clarithromycin may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Bardep Plus Tablet and clarithromycin, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
AlprazolamKetoconazole
Critical
How does the drug interact with Bardep Plus Tablet:
Co-administration of Bardep Plus Tablet with Ketoconazole may considerably increase the blood levels of Bardep Plus Tablet, which may result in side effects.

How to manage the interaction:
Although there is an interaction between Bardep Plus Tablet and Ketoconazole, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamCobicistat
Critical
How does the drug interact with Bardep Plus Tablet:
Co-administration of Bardep Plus Tablet with Cobicistat may considerably increase the blood levels and effects of Bardep Plus Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Bardep Plus Tablet and Cobicistat, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamRitonavir
Severe
How does the drug interact with Bardep Plus Tablet:
Co-administration of Bardep Plus Tablet with Ritonavir may considerably increase the blood levels of Bardep Plus Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Bardep Plus Tablet and Ritonavir, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamSufentanil
Severe
How does the drug interact with Bardep Plus Tablet:
Using Bardep Plus Tablet together with Sufentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Bardep Plus Tablet and Sufentanil may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a regular sleep pattern. Do not take a nap during day time.

  • Avoid watching TV and using mobiles or laptops just before bedtime.

  • Maintain a diet rich in fruits, vegetables, and whole grains. Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen anxiety.

  • To boost your mental health, dark green leafy vegetables, in particular, are brain protective. Nuts, seeds, and legumes, such as beans and lentils, are also excellent brain foods.

  • Do regular exercise 

  • Avoid the consumption of alcohol as it may increase drowsiness.

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT

Bardep Plus Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Bardep Plus Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Bardep Plus Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. If the benefits are more than the potential risks, a doctor may rarely prescribe it in some life-threatening situations. Please consult your doctor. 

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Bardep Plus Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Caution

Bardep Plus Tablet may cause dizziness or drowsiness in some people. It is an offence to drive if Bardep Plus Tablet affects you. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Bardep Plus Tablet .

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Liver

Caution

Take Bardep Plus Tablet with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose if necessary based on your condition.

bannner image

Kidney

Caution

Take Bardep Plus Tablet with caution, especially if you have a pre-existing or a history of kidney disease. Please consult your doctor before taking Bardep Plus Tablet . Your doctor may adjust the dose if necessary based on your condition.

bannner image

Children

Caution

Bardep Plus Tablet should not be used by children, as efficacy and safety have not been established.

Have a query?

FAQs

Bardep Plus Tablet is used to treat depression, a mood disorder that causes a persistent feeling of sadness and loss of interest.

Bardep Plus Tablet contains a combination of two medicines called alprazolam and fluoxetine. Alprazolam is a benzodiazepine (BZD) that increases the action of GABA (gamma-aminobutyric acid), a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels, a chemical messenger that improves mood.

Bardep Plus Tablet may cause common side effects like nausea, vomiting, diarrhea, confusion, memory impairment, drowsiness, tiredness, low sexual desire, and uncoordinated body movements. These side effects do not require any medical attention it resolves on their own. If it persists, contact your doctor immediately.

Yes, Bardep Plus Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Bardep Plus Tablet only in dose and duration as advised by your doctor.

No, you are not recommended to take Bardep Plus Tablet with codeine as co-administration of these medicines may cause breathing problems, drowsiness, and coma. However, before using Bardep Plus Tablet with codeine and other opioids, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Inform your doctor if you have liver or kidney problems, closed-angle glaucoma, cardiac diseases, diabetes, pulmonary insufficiency, bleeding disorders, epilepsy and electro-convulsive therapy before taking Bardep Plus Tablet .

Country of origin

India
Other Info - BAR0187

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/product/1657/smpc
  2. https://www.drugs.com/drug-interactions/alprazolam-index.html
  3. https://www.medicineindia.org/pharmacology-for-generic/844/fluoxetine-alprazolam?__cf_chl_captcha_tk__=ecd6c2923f63ac697d2c04ec539962719a5bd393-161199975
  4. https://medlineplus.gov/druginfo/meds/a689006.html
  5. https://www.medicines.org.uk/emc/medicine/25737?__cf_chl_captcha_tk__=462f8ffae499ab071a8edc7b5fc42020e67922ef-1612002540-0-ASWRGc-3j3qIE8dikdGz_rP97UOqJgqx9aaTrplIfXYiPksfhGz2Ys2fXjshHuBUYJ7uc9u8qJApC_ACtRdEiUPrfZA6W64BL42ZLn1o--R221RENVRXktL0-WUkSrKOEKGXtzvBReTv4RTPWctVXQdnD7LjqwtDKXsXSDGIL-JuMTfWqmiLvzBxYNeoZzQf5DpWZD67AGmAEB-Lvicf-KI4UK6JYmQdRenpzSYIZl-5rlzUyqWaOkhMnoQqCb1FE8rvWXa6syqtLi4AyVkxswBG4mOMLzdKshGNR9Z74GWlH1lFfkYl9tlXALRip8immFwgRCKbA9HeH9OtJg4xDMkLNWiN-DH2MJJ0ATz_-08k5KZvS4fjTC6_RYIQbDIUCIFzxj40_c1A9KJSRNZ4mxJlSAvxlLBqhzTByiyzeo08edeqSREFePFc4wnx1pT7r1p_x2HxtfWuA036mmnw12Pmq19F2sH10mPvlTX9RaoXysX7eL7nsVxDbznfW_LeSP8vNz7Je0xim__yP8k_R35az_BbmiZ0EexUq1eb2Em3#PRODUCTINFO

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