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compositionComposition:AZELAIC ACID-20%W/W
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Prescription Medicine
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Azecil Cream 20% is used to treat acne (pimples). It kills bacteria and reduces inflammation, making acne less visible, less red, and less irritated. It also helps the skin renew itself and reduces the formation of pimples and blackheads.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

AZELAIC ACID-20%W/W

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Azecil Cream 20%

Azecil Cream 20% is a prescription topical medicine used to treat common skin conditions like acne and inflammatory rosacea. It works by targeting the bacteria that cause breakouts, reducing swelling, and helping to clear blocked pores. It is designed to help improve the texture and appearance of your skin over time.

For the best results, you should apply Azecil Cream 20% regularly, typically once or twice a day as directed by your doctor. It is important to apply this medication to clean, completely dry skin to avoid unnecessary irritation. Combining this treatment with a gentle skincare routine, staying hydrated, and avoiding trigger foods can significantly support your skin's healing process.

While using Azecil Cream 20%, you may notice some mild, temporary skin reactions like itching, burning, or redness at the application site. These symptoms usually improve as your skin gets used to the treatment, but you should speak to your doctor if they become severe. If you experience signs of a serious allergic reaction, such as a severe rash, swelling, or difficulty breathing, seek medical help immediately.

Before starting Azecil Cream 20%, tell your healthcare provider if you have highly sensitive skin, eczema, or any other pre-existing skin conditions. Do not use this medicine if you have had an allergic reaction to Azecil Cream 20% or any of its ingredients in the past. Your doctor will help determine if this topical treatment is safe for your specific skin type.

Using other medicated skin products, harsh soaps, or alcohol-based cosmetics alongside this treatment can increase skin irritation and dryness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Azecil Cream 20% to ensure it is safe for you and your baby.

Uses of Azecil Cream 20%

This medicine is used to treat acne and rosacea by reducing inflammation, controlling bacteria, and helping keep skin pores clear. The detailed uses of Azecil Cream 20% are as follows:

  • Acne vulgaris: Azecil Cream 20% helps clear pimples, blackheads, and whiteheads by reducing the growth of acne-causing bacteria and preventing clogged pores.
  • Inflammatory rosacea: Azecil Cream 20% helps reduce the redness, swelling, and bumps associated with rosacea, soothing inflamed facial skin and improving its appearance.
  • Post-inflammatory hyperpigmentation and melasma: Azecil Cream 20% may be prescribed to help reduce excess skin pigmentation, including acne marks and melasma. It helps promote a more even skin tone and is particularly useful for people with darker skin types, although results may take several months of consistent use.

Key Benefits

Azecil Cream 20% helps improve acne- and rosacea-prone skin by reducing inflammation, controlling bacteria, and promoting clearer skin. Its benefits include:

  • Helps reduce acne-causing bacteria and inflammation, allowing pimples to heal faster and lowering the risk of new breakouts.
  • Helps clear clogged pores, reducing blackheads, whiteheads, and other acne lesions.
  • Reduces the redness, swelling, and bumps associated with rosacea, improving overall skin comfort and appearance.
  • Promotes smoother skin texture and a more even-looking complexion with regular use.
  • Provides gradual, long-term improvement in acne and rosacea symptoms when used consistently as directed.
Side effects of Azecil Cream 20%
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Moisturize frequently with thick, broad-spectrum moisturizers containing sunscreen.
  • Use warm water for short baths, and gentle cleansers.
  • Pat dry and apply moisturizer immediately.
  • Use a humidifier to add moisture to the air, and choose breathable fabrics like cotton and silk.
  • Wash clothes with fragrance-free detergents to minimize irritation.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the key steps to manage medication-triggered Burning At Application Site:
  • Consult and seek guidance from a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate the issue.
  • Depending on the location and severity of the burning, your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment.
  • Keep the affected area clean to promote healing and prevent further irritation.
  • Schedule follow-up appointments with your healthcare professional to monitor your symptoms and adjust your treatment plan as needed.
  • If the burning or irritation persists or worsens, seek medical attention for further guidance and treatment.
  • Inform your doctor right away if you notice any changes in your skin colour where you applied the medicine; they might need to adjust your dose or stop it temporarily.
  • If needed, your doctor may suggest using creams containing medicines like retinoids, hydroquinone, or azelaic acid to help lighten the discoloration.
  • Apply sunscreen with a high SPF when going outside to prevent further darkening of the affected areas.
  • Wearing protective clothing and staying in the shade can also help keep the discoloration from getting worse.
  • Avoid smoking and using harsh chemicals, as they can harm your skin and cause more discoloration.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Take the advised amount of Azecil Cream 20% and apply it as a thin layer on the clean and dry affected area as prescribed by your doctor.
  • Azecil Cream 20% is for external use only. Avoid contact with the eyes, ears, nose, and mouth. If Azecil Cream 20% comes into contact with the eyes, nose, or mouth, rinse with water immediately.

How Azecil Cream 20% Works

Azecil Cream 20% works through multiple actions directly on the skin to address acne and rosacea. First, it acts as a mild exfoliant by normalizing how your skin sheds dead cells. This prevents dead skin cells from clumping together and clogging your pores, which is the primary cause of blackheads and pimples. Second, Azecil Cream 20% has natural antibacterial properties that target and slow down the growth of bacteria responsible for inflammatory breakouts. Finally, it acts as an antioxidant and anti-inflammatory agent, calming the deep redness and swelling in the skin tissues, which is particularly beneficial for managing rosacea flare-ups.
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Alcohol

Caution

The interaction of Azecil Cream 20% with alcohol is unknown. Please consult your doctor in case of any concerns.

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Pregnancy

Caution

Please consult your doctor before using Azecil Cream 20% if you are pregnant or planning to conceive.

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Breast Feeding

Caution

There are limited studies on how Azecil Cream 20% affects breastfed infants. Please consult your doctor before using Azecil Cream 20% if you are breastfeeding.

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Driving

Not applicable

Azecil Cream 20% usually does not interfere with your driving ability and is safe to use.

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Liver

Consult your doctor

Please consult your doctor before using Azecil Cream 20% if you suffer from liver disease.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Azecil Cream 20% in patients with Kidney problems, please consult a doctor.

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Children

Caution

Azecil Cream 20% is not recommended for use in children below 12 years as the safety and efficacy have not been established.

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Heart

Consult your doctor

No significant cardiac issues have been reported. However, consult a doctor before use, especially if you have pre-existing heart conditions or are taking heart medications.

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Geriatrics

Consult your doctor

No specific geriatric problems have been reported that would limit the use of Azecil Cream 20% in elderly patients. However, consult a doctor before use.

What if I have taken an overdose of Azecil Cream 20%

Because Azecil Cream 20% is a topical medication applied to the skin, a dangerous overdose is highly unlikely. However, if you or someone else accidentally swallows this medicine, seek immediate medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Identify and avoid rosacea triggers: If you are treating rosacea, keep a diary to track your flare-ups. Common triggers include spicy foods, hot beverages, alcohol, and extreme temperatures.
  • Use broad-spectrum sunscreen daily: This treatment can make your skin more sensitive to the sun. Apply a gentle, mineral-based sunscreen (SPF 30 or higher) daily to protect your skin from UV damage and prevent hyperpigmentation.
  • Choose gentle skincare products: Avoid harsh facial scrubs, astringents, alcohol-based toners, or peeling agents that can strip your skin barrier and worsen irritation.
  • Stay hydrated and eat a balanced diet: Drinking plenty of water and eating foods rich in antioxidants, like leafy greens and berries, helps support natural skin healing and reduces overall inflammation.
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Have a query?

How Soon It Starts Working

The time required for Azecil Cream 20% to start to work: The time required for Azecil Cream 20% to show its action is clinically unknown.

The time for which the effects of Azecil Cream 20% last: The duration of action for Azecil Cream 20% is clinically unknown.

What if you forget to take Azecil Cream 20%

If you forget to apply Azecil Cream 20%, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular routine. Do not apply a double amount to make up for the missed application.

Storage

•Store Azecil Cream 20% at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Keep away from sensitive areas: Avoid getting Azecil Cream 20% in your eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse the area thoroughly with plenty of cool water.
  • Check the tube seal: Before using a new tube, ensure the protective seal is intact. Do not use the product if the tube appears damaged, leaking, or punctured.
  • Be patient with results: It may take up to 4 weeks of consistent daily use to see noticeable improvements in your skin. Continue using the medicine as prescribed even if you do not see immediate changes.
  • Watch for skin lightening: In rare cases, this medication can cause temporary skin lightening, especially in people with darker skin tones. Monitor your skin carefully and report any unusual color changes to your doctor.
  • Do not apply to broken skin: Avoid applying this medication to open wounds, windburned, sunburned, or severely irritated skin.

Drug-Drug Interactions

verifiedApollotooltip
  • Other topical peeling agents (such as salicylic acid, benzoyl peroxide, or retinoids): Using these alongside Azecil Cream 20% may significantly increase the risk of severe skin dryness, redness, and irritation.
  • Abrasive or medicated soaps and cleansers: Combining these products with your treatment can strip the skin barrier, leading to heightened sensitivity and discomfort.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

  • No clinically significant food interactions are known with Azecil Cream 20% when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIACNE]

FAQs

Azecil Cream 20% is used to treat acne. It also prevents the outer layer of skin from becoming too thick, which can clog pores and lead to the formation of blackheads and whiteheads.
Azecil Cream 20% works by inhibiting the growth of acne-causing bacteria (Propionibacterium acnes). It reduces inflammation, making acne less visible, less red, and less irritated. Azecil Cream 20% also helps the skin renew itself and reduces pimples and blackhead formation.
Azecil Cream 20% is to be used as advised by the doctor. Generally, it is recommended to be used twice daily, in the morning and evening. However, the duration of use can vary from person to person and depends on the severity of the acne.
Clean the affected area using a mild cleanser and pat dry. Apply the advised amount with clean and dry hands to the affected areas of the skin. Rub it in gently. Wash your hands before and after applying. Do not put a dressing or bandage on the affected areas.
Common side effects of Azecil Cream 20% include dryness, peeling, a burning sensation, and itching. These side effects may not occur in every patient using this medication and may differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.
While it's generally safe for long-term use, it's essential to consult a dermatologist to assess your needs and monitor for any potential side effects. However, you should not use it for more than 12 months at any time.
Yes, you can apply makeup after using this medicine. However, you should wait a few minutes to allow Azecil Cream 20% to dry completely and absorb into your skin first. It is also best to choose oil-free and non-comedogenic cosmetics to avoid clogging your pores. Talk to your doctor if you have questions about your skincare products.
Azecil Cream 20% is generally considered safe to use during pregnancy, but only if your doctor determines it is clearly needed. Very little of the medicine is absorbed into your body through the skin. However, you should always consult your doctor before starting any new skincare treatment during pregnancy.
Yes, some mild peeling, dryness, or flaking is a common side effect, especially during the first few weeks of starting the treatment. If the peeling becomes severe or causes discomfort, you can ask your doctor about reducing your applications to once a day or every other day. Talk to your doctor if the flaking persists.
Yes, using a gentle, oil-free moisturizer is highly recommended to help manage dryness or peeling. Apply your moisturizer only after Azecil Cream 20% has dried completely on your skin. Talk to your doctor or pharmacist for recommendations on skin-friendly moisturizers.
Yes, but you must take extra precautions. This medication can make your skin more sensitive to sunlight and UV rays, which can trigger redness or dark spots. Always apply a broad-spectrum sunscreen of SPF 30 or higher and wear protective clothing when outdoors. Talk to your doctor if you experience a sunburn.
Azecil Cream 20% can be used on sensitive skin, but it may cause initial stinging, burning, or redness. Your doctor may advise you to start by applying it once a day or every other day to help your skin build tolerance. Talk to your doctor about the best approach for your sensitive skin.
If you experience severe or unbearable itching, burning, or redness, wash the medication off your skin immediately. You should stop using the product and contact your healthcare provider right away to evaluate if you are having an allergic reaction or severe irritation. Talk to your doctor before restarting the treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.285 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 20428Slr016 Azelex Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. Azelaic acid. 2007. [Accessed on 28 Jan. 2019]Check here
  4. Azelaic acid. 2010. [Accessed on 05 Feb. 2019]Check here
  5. Finacea 15% Gel - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 25th Nov 2025]Check here
  6. Schulte BC, Wu W, Rosen T. Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application. National Institute of Health NLM, National Centre for Biotechnology Information. PubMed.gov. September 2015. [Accessed on May 2nd 2022]Check here
  7. Rivero AL, Whitfeld M. An update on the treatment of rosacea. National Institute of Health NLM, National Centre for Biotechnology Information. PubMed Central. 2018 February. [Accessed on May 2nd 2022]Check here

Country of origin

India
Other Info - AZ11889
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