apollo
0
  1. Home
  2. Medicine
  3. Azadine-O Tablet 14's

Offers on medicine orders
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Azadine-O Tablet is used in treating Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. It contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

Read more
rxMedicinePrescription drug

Whats That

tooltip

Composition :

AZACITIDINE-300MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Azadine-O Tablet

Azadine-O Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of acute myeloid leukaemia in adults who improved after chemotherapy but could not complete intensive curative therapy. Acute myeloid leukaemia is a type of cancer that forms in the blood-forming cells of the bone marrow.

Azadine-O Tablet contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

In some cases, Azadine-O Tablet may cause side effects such as nausea, vomiting, diarrhoea, constipation, fatigue and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Azadine-O Tablet if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azadine-O Tablet . This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Azadine-O Tablet

Azadine-O Tablet is used in the treatment of Acute myeloid leukaemia. The detailed uses of Azadine-O Tablet are as follows:<br/>• Myelodysplastic syndrome (MDS): Azadine-O Tablet is used to treat all subtypes of MDS, a group of disorders where the bone marrow produces poorly formed or dysfunctional blood cells, leading to anemia, infections, or bleeding.<br/>• Acute myeloid leukemia (AML): Azadine-O Tablet is used in patients with AML who are not eligible for stem cell transplantation. It helps reduce the number of abnormal blood cells and promotes the production of healthy ones.<br/>

Directions for Use

• Azadine-O Tablet can be taken with or without food, as food does not affect its absorption or effectiveness.• Azadine-O Tablet is usually taken once daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the tablet as a whole with a glass of water.• Do not break, crush or chew Azadine-O Tablet .

Medicinal Benefits

Azadine-O Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of adult patients with acute myeloid leukaemia who achieved first complete remission (all signs and symptoms of cancer have disappeared) or complete remission with incomplete blood count recovery following intensive induction chemotherapy and are not able to complete intensive curative therapy. Azadine-O Tablet contains Azacitidine, a nucleoside metabolic inhibitor which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

How Azadine-O Tablet Works

Azadine-O Tablet contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Azadine-O Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Azadine-O Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink clear fluids like water and eat a high-fiber diet.
  • Practice to get enough rest.
  • Take mild pain relievers.
  • Apply a hot water bottle or heated wheat pack to your abdomen.
  • Avoid taking foods that are fatty, spicy, or rich.
  • Do not take alcohol, tea, and coffee.
  • Practice technics like biofeedback, hypnosis, or other methods for stress relief.
  • Consult your doctor, if you experience severe abdominal pain or pain that comes back.
  • Eat a well-balanced diet, and avoid highly processed foods.
  • Regular exercise can help prevent ascites.
  • Maintain a healthy weight, as obesity is a risk factor for ascites.
  • Limit salt intake; try to consume no more than 2,000–4,000 milligrams of salt per day.
  • Avoid alcohol, as it can damage your liver and increase the risk of cirrhosis.
  • Practice safe sex, unprotected sex can lead to hepatitis, which can damage the liver and cause cirrhosis.
  • Get vaccinated for diseases like hepatitis, influenza, and pneumococcal.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Azadine-O Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Azadine-O Tablet may include diarrhoea, nausea, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Azadine-O Tablet if you are allergic to any of its components or if you are breastfeeding. Inform the doctor if you have liver or kidney problems. Seek medical attention if you experience symptoms of neutropenia/low white blood cells (fever or chills, feeling very tired or weak, body aches, and unusual headache) or thrombocytopenia/low platelet count (unusual bleeding or bruising). Consult the doctor if you are pregnant, plan to become pregnant, or if you plan to father a child.

Drug-Drug Interactions

verifiedApollotooltip
AzacitidineYellow fever vaccine
Critical

Drug-Drug Interactions

Login/Sign Up

AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azadine-O Tablet:
Taking Yellow fever vaccine with Azadine-O Tablet can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azadine-O Tablet and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with Azadine-O Tablet:
Taking Adalimumab with Azadine-O Tablet may raise the risk of severe infections.

How to manage the interaction:
Taking Azadine-O Tablet with Adalimumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineVoclosporin
Severe
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with Voclosporin may lead to a higher chance of severe infections and certain cancers, such as skin cancer and lymph gland cancer (lymphoma).

How to manage the interaction:
Taking Azadine-O Tablet with Voclosporin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in coughing fluid, weight loss, red or inflamed skin, body sores, and pain or burning during urination, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with Deferiprone can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Azadine-O Tablet with Deferiprone can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azadine-O Tablet:
The use of fingolimod in conjunction with Azadine-O Tablet may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azadine-O Tablet with Fingolimod can possibly result in an interaction, but it can be taken if your doctor has advised it. However, Consult a doctor immediately if you have a fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azadine-O Tablet:
Coadministration of Filgrastim with Azadine-O Tablet can reduce the effects of Filgrastim.

How to manage the interaction:
Although there is an interaction between filgrastim and Azadine-O Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet and leflunomide together may increase the chances of developing severe infections.

How to manage the interaction:
Although there is an interaction between leflunomide and Azadine-O Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineGolimumab
Severe
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with Golimumab can raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azadine-O Tablet with Golimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineBCG vaccine
Severe
How does the drug interact with Azadine-O Tablet:
Taking BCG vaccine with Azadine-O Tablet can increase the risk of infection.

How to manage the interaction:
Co-administration of Azadine-O Tablet with BCG vaccine can result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Azadine-O Tablet and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly as it helps maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY
bannner image

Alcohol

Consult your doctor

It is not known if alcohol affects Azadine-O Tablet . Please consult your doctor.

bannner image

Pregnancy

Unsafe

Azadine-O Tablet can harm the unborn baby. Avoid becoming pregnant during treatment with Azadine-O Tablet . Consult the doctor immediately if you become pregnant during treatment with Azadine-O Tablet .

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding during treatment with Azadine-O Tablet and for one week after the last dose.

bannner image

Driving

Consult your doctor

It is unknown if Azadine-O Tablet affects your ability to drive. Drive only if you are alert.

bannner image

Liver

Caution

If you have a history of liver disease, inform your doctor before taking Azadine-O Tablet .

bannner image

Kidney

Caution

If you have a history of kidney disease, inform your doctor before taking Azadine-O Tablet .

bannner image

Children

Unsafe

Azadine-O Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

Azadine-O Tablet is used to treat Acute myeloid leukaemia.

Azadine-O Tablet works by helping bone marrow in the production of normal blood cells and killing abnormal cells in the bone marrow.

Azadine-O Tablet may affect fertility in men and women. Consult the doctor if you have any concerns.

The doctor will prescribe anti-nausea medicine to help prevent nausea and vomiting during treatment with Azadine-O Tablet . Take the anti-nausea medicine 30 minutes before each dose of Azadine-O Tablet or as the doctor advises.

If you vomit after taking a dose Azadine-O Tablet , avoid taking another dose on the same day. Take the next dose at the regular time the next day. Talk to the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - AZA0110

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button
Buy Now
Add to Cart