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compositionComposition:ATRACURIUM-25MG
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Prescription Medicine
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Atraplen 25 mg Injection is used to reduce and relieve muscle spasms (excessive tension in the muscles) occurring during surgery in intensive care. It contains Atracurium, which stops sending pain signal to the brain, relieves muscle stiffness or muscle spasm. It is also used during general anaesthesia to ease tracheal intubation (a tube into the windpipe) and controlled ventilation.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ATRACURIUM-25MG

Manufacturer/Marketer :

Nicholas Healthcare Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Atraplen 25 mg Injection

Atraplen 25 mg Injection is a prescription medicine used to relax muscles during surgical procedures and when a patient requires breathing support from a ventilator. It temporarily prevents muscle movement, allowing doctors to perform procedures safely and effectively. It is commonly used to make insertion of a breathing tube easier and to keep muscles relaxed during surgery.

Because Atraplen 25 mg Injection is given only in hospitals or specialised healthcare settings, it is administered as an injection or continuous infusion by trained medical professionals. Since it is given directly into a vein, food does not affect how it works. Following your healthcare team's recovery instructions can help support a smooth recovery after your procedure.

While receiving Atraplen 25 mg Injection, some people may experience temporary side effects such as skin flushing, mild skin rash, hives, or a temporary drop in blood pressure. You will be continuously monitored throughout your procedure, allowing your medical team to quickly identify and manage any unexpected reactions.

Before receiving Atraplen 25 mg Injection, tell your doctor if you have neuromuscular conditions such as myasthenia gravis, previous reactions to anesthesia, severe allergies, or any history of unusual responses to muscle-relaxing medicines. Do not receive Atraplen 25 mg Injection if you have had a severe allergic reaction to Atraplen 25 mg Injection or similar muscle-relaxing medicines from the same family.

Certain medicines, including some antibiotics, anesthetics, lithium, and magnesium-containing products, can affect how Atraplen 25 mg Injection works. If you are pregnant, breastfeeding, an older adult, or the parent of a child receiving Atraplen 25 mg Injection, discuss any concerns with your doctor before the procedure. Atraplen 25 mg Injection is often preferred in patients with kidney or liver impairment because its breakdown does not depend heavily on these organs. It is also commonly used in operating rooms and intensive care units where reliable muscle relaxation is needed.

Uses of Atraplen 25 mg Injection

Atraplen 25 mg Injection is used in the treatment of Muscle contraction during surgery. The detailed uses of Atraplen 25 mg Injection are as follows:

  • Muscle relaxation during surgery: It relaxes skeletal muscles, which helps surgeons perform operations safely and with fewer complications.
  • Support for mechanical ventilation: It relaxes the chest and airway muscles, allowing a breathing machine to work smoothly for patients in intensive care.
  • Tracheal intubation: It relaxes the throat muscles, making it easier and safer for a healthcare provider to insert a breathing tube.

Key Benefits

Atraplen 25 mg Injection helps provide controlled muscle relaxation during surgical procedures and intensive care treatment. By relaxing the muscles effectively, it supports safe medical procedures and helps healthcare professionals manage breathing support when needed. Benefits may include:

  • Provides reliable muscle relaxation during surgical procedures.
  • Helps prevent involuntary muscle movements, allowing greater surgical precision.
  • Facilitates endotracheal intubation and airway management during anesthesia.
  • Supports better synchronization with mechanical ventilation in critically ill patients.
  • Helps reduce the effort required for assisted breathing during intensive care treatment.
  • Can be used in patients with impaired kidney or liver function under appropriate medical supervision.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Atraplen 25 mg Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Atraplen 25 mg Injection Works

Atraplen 25 mg Injection contains Atracurium, which helps relax the muscles by temporarily blocking the signals between nerves and muscles. This makes it easier for healthcare professionals to perform procedures such as surgery or assist with breathing support when needed. It works for a short period and the muscle function gradually returns as the medicine is naturally broken down and cleared from the body.
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Alcohol

Unsafe

Avoid consumption of alcohol after taking Atraplen 25 mg Injection as it may increase the risk of side effects.

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Pregnancy

Consult your doctor

If you are pregnant, inform your doctor before receiving Atraplen 25 mg Injection; Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before receiving Atraplen 25 mg Injection; Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Unsafe

Atraplen 25 mg Injection causes sleepiness and drowsiness. So, avoid driving or operating heavy machinery after taking this medicine.

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Liver

Caution

Atraplen 25 mg Injection should be used with caution in patients with liver diseases. Your doctor may adjust the dose of Atraplen 25 mg Injection before prescribing.

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Kidney

Caution

Atraplen 25 mg Injection should be used with caution in patients with kidney diseases. Your doctor may adjust the dose of Atraplen 25 mg Injection before prescribing.

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Children

Consult your doctor

Atraplen 25 mg Injection use is not recommended in neonates (children under the age of one month). Your doctor will decide the dose of Atraplen 25 mg Injection based on age and condition of your child.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Atraplen 25 mg Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Atraplen 25 mg Injection

Since medical professionals inject this medication under strict monitoring, an overdose is highly unlikely. If an overdose occurs, your healthcare team is trained to immediately manage it by providing breathing support and using medicines to reverse the muscle relaxation.

Diet & Lifestyle Advise

  • Follow fasting instructions carefully: Do not eat or drink anything as directed by your surgical team before the procedure, as fasting helps reduce the risk of serious breathing complications during anesthesia.
  • Get adequate rest after the procedure: Rest quietly following your surgery to allow your muscles time to recover and regain their full strength.
  • Avoid walking without assistance: Do not get out of bed, stand, or walk on your own until your healthcare team confirms that the effects of the medicine have completely worn off.
  • Stay well hydrated when permitted: Once your doctor allows you to drink fluids, consume plenty of water to support recovery and help your body process fluids effectively.
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How Soon It Starts Working

The time required for Atraplen 25 mg Injection to start to work: The time required for Atraplen 25 mg Injection to start to work is 2 to 3 minutes after administration. 

The time for which the effects of Atraplen 25 mg Injection last: The effect of Atraplen 25 mg Injection lasts for 20 to 35 minutes.

What if you forget to take Atraplen 25 mg Injection

Because Atraplen 25 mg Injection is given only by healthcare professionals in a controlled medical setting, it is not possible for you to miss a dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Atraplen 25 mg Injection out of the sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.

Drug Warnings

  • Inspect the solution before use: The solution should appear clear and colorless to pale yellow. Do not use it if it appears cloudy, discolored, or contains visible particles.
  • Inform your medical team about allergies: Tell your healthcare providers about any allergies, especially previous reactions to anesthesia, muscle relaxants, or other medicines.
  • Expect close monitoring during treatment: Your heart rate, blood pressure, oxygen levels, and breathing will be continuously monitored while Atraplen 25 mg Injection is being administered.
  • Discuss any muscle or nerve disorders: Inform your doctor if you have myasthenia gravis or any other condition affecting the muscles or nervous system, as these conditions may alter your response to the medicine.
  • Inform your doctor about electrolyte abnormalities: Tell your healthcare provider if you have abnormal blood levels of minerals such as potassium or calcium, as these may affect how the medicine works.
  • Avoid activities requiring coordination after anesthesia: Do not drive, operate machinery, or perform tasks requiring full alertness and coordination for at least 24 hours after anesthesia, or for as long as advised by your doctor.

verifiedApollotooltip
  • Inhalation anesthetics (e.g., isoflurane, halothane): Taking these medicines alongside Atraplen 25 mg Injection may increase and prolong its muscle-relaxing effects.
  • Certain antibiotics (e.g., aminoglycosides, polymyxins, tetracyclines): These medicines may enhance the effects of Atraplen 25 mg Injection and prolong muscle relaxation.
  • Lithium or magnesium-containing medicines: Combining these with Atraplen 25 mg Injection may increase its muscle-relaxing effects and raise the risk of excessive muscle weakness.
    Other muscle-relaxing medicines: Taking these alongside Atraplen 25 mg Injection may increase the risk of prolonged or excessive muscle weakness.

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Habit Forming

No

Therapeutic Class

[MUSCLE RELAXANTS/SKELETAL MUSCLE RELAXANTS]

FAQs

Atraplen 25 mg Injection is used to reduce and relieve muscle spasms (excessive tension in the muscles) occurring during surgery in intensive care.
Atraplen 25 mg Injection contains 'Atracurium' that relaxes the muscles by blocking the impulses from the nerves. It is used for skeletal muscle relaxation during surgery.
Atraplen 25 mg Injection causes sleepiness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel sleepy or drowsy.
Atraplen 25 mg Injection is safe and effective when administered to patients with severe heart disease. However, rapid administration of large doses may occasionally produce transient hypotension in patients with heart problems. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Do not use Atraplen 25 mg Injection have had myasthenia gravis or Eaton-Lambert syndrome, severe electrolyte disorder, asthma-like symptoms (a history of allergy, asthma or bronchospasm), burns, and lack of adequate circulatory filling (hypovolaemia), pregnant or breastfeeding mother. Avoid driving or performing hazardous tasks until you know how Atraplen 25 mg Injection will affect you, and your reactions could be impaired.
Atraplen 25 mg Injection is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer or the fridge.
Atraplen 25 mg Injection is given by IV injection administered by a healthcare professional under carefully controlled conditions. Do not self-administer Atraplen 25 mg Injection.
The common side effects of the Atraplen 25 mg Injection are tachycardia (rapid heartbeat), temporary hypotension (low blood pressure), wheezing, bronchospasm (asthma-like symptoms), skin flushing, and urticaria (nettle rash). However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Atraplen 25 mg Injection usually begins working within 2 to 3 minutes after intravenous administration. Your anesthesiologist will monitor its effects throughout the procedure.
No. Atraplen 25 mg Injection only relaxes muscles and does not provide pain relief or cause sleep. It is used together with anesthetics and pain-relieving medicines during procedures.
Atraplen 25 mg Injection is often preferred for people with kidney or liver impairment because it is broken down mainly through Hofmann elimination and ester hydrolysis rather than relying heavily on these organs.
Atraplen 25 mg Injection may be used during pregnancy when medically necessary, such as during surgical procedures. Your doctor will carefully weigh the benefits and potential risks before use.
Doctors may allow the Atraplen 25 mg Injection to wear off naturally or use anticholinesterase medicines such as neostigmine to help restore normal muscle strength more quickly.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

401, Mohan Place, L.S.C., Block-C, Saraswati Vihar, Delhi-110034, INDIA, Delhi, India, 110034
Other Info - ATR0170
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