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  3. Atoxim-S 1.5 gm Injection 1's

Atoxim-S 1.5 gm Injection 1's, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Atoxim-S 1.5 gm Injection is used to treat various bacterial infections in the body. It contains Ceftizoxime and Sulbactam. Ceftizoxime inhibits the synthesis of the bacterial cell wall (a protective covering necessary for their survival), causing damage to the bacterial cell wall and eventually leading to the death of the bacterial cell. Sulbactam decreases bacterial resistance and enhances the activity of Ceftizoxime against the bacteria. Together, it helps treat bacterial infections.

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Composition :

CEFTIZOXIME-1000MG + SULBACTAM-500MG

Manufacturer/Marketer :

Zymes Bioscience Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Atoxim-S 1.5 gm Injection

Atoxim-S 1.5 gm Injection belongs to the group of medicines called antibiotics. It is used to treat a wide variety of bacterial infections in the body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

Atoxim-S 1.5 gm Injection contains Ceftizoxime (third-generation cephalosporin antibiotic) and Sulbactam (beta-lactamase inhibitor). It works by inhibiting the synthesis of the bacterial cell wall (a protective covering) that is necessary for their survival. This causes damage to the bacterial cell wall and eventually leads to the death of the bacterial cell. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Together, Atoxim-S 1.5 gm Injection helps treat bacterial infections.

Atoxim-S 1.5 gm Injection will be administered by a healthcare professional; do not self-administer. In some cases, Atoxim-S 1.5 gm Injection may cause injection site reactions, diarrhoea, nausea, vomiting, headache, rash, stomach upset, and indigestion. Most of these side effects of Atoxim-S 1.5 gm Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know about your medical and medication history to avoid the occurrence of potential interactions. Atoxim-S 1.5 gm Injection should only be given during pregnancy when the need has been established. Hence, inform your doctor if you are pregnant, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Atoxim-S 1.5 gm Injection therapy against the risk to your baby. Breastfeeding should be avoided unless instructed by the doctor. Consumption of alcohol should be avoided while on treatment with Atoxim-S 1.5 gm Injection.

Uses of Atoxim-S 1.5 gm Injection

Atoxim-S 1.5 gm Injection is used in the treatment of various bacterial infections by combining the antibacterial actions of Ceftriaxone and Sulbactam. The detailed uses of Atoxim-S 1.5 gm Injection are as follows:<br/>• Treats respiratory tract infections: Atoxim-S 1.5 gm Injection acts effective against lung and sinus infections including pneumonia, bronchitis, and sinusitis.<br/>• Manages ENT infections: Atoxim-S 1.5 gm Injection is used for bacterial infections of the ear and throat such as otitis media and tonsillitis.<br/>• Effective in urinary tract infections: Atoxim-S 1.5 gm Injection treats bladder and kidney infections caused by susceptible bacteria.<br/>• Controls skin and soft tissue infections: It is indicated for cellulitis, wound infections, and other soft tissue infections.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Atoxim-S 1.5 gm Injection will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Atoxim-S 1.5 gm Injection contains Ceftizoxime and Sulbactam. Ceftizoxime is a third-generation cephalosporin antibiotic, and Sulbactam is a beta-lactamase inhibitor. It acts by blocking the synthesis of the bacterial cell wall, which is required for their survival. This damages the bacterial cell wall and eventually kills the bacterial cell. Sulbactam reduces bacterial resistance while increasing the activity of Ceftizoxime against bacteria. Together, Atoxim-S 1.5 gm Injection helps to treat bacterial infections.

How Atoxim-S 1.5 gm Injection Works

Atoxim-S 1.5 gm Injection contains Ceftizoxime (third-generation cephalosporin antibiotic) and Sulbactam (beta-lactamase inhibitor). It works by inhibiting the synthesis of the bacterial cell wall (a protective covering) that is necessary for their survival. This causes damage to the bacterial cell wall and eventually leads to the death of the bacterial cell. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Together, Atoxim-S 1.5 gm Injection helps treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Atoxim-S 1.5 gm Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Atoxim-S 1.5 gm Injection

As Atoxim-S 1.5 gm Injection is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of Atoxim-S 1.5 gm Injection may include seizure (convulsions).

Drug Warnings

Before taking the Atoxim-S 1.5 gm Injection, inform your doctor about all of your medical problems, sensitivities, and drugs. If you are pregnant or breastfeeding, check with your doctor before taking Atoxim-S 1.5 gm Injection. For effective outcomes, it is recommended that you complete the entire course of Atoxim-S 1.5 gm Injection as prescribed by your doctor. If you are received or scheduled for immunizations, inform your doctor. Atoxim-S 1.5 gm Injection should be used cautiously in people with Clostridium difficile-associated diarrhoea.

Drug-Drug Interactions

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CeftizoximeCholera, live attenuated
Severe
CeftizoximeCholera vaccines
Severe

Drug-Drug Interactions

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CeftizoximeCholera, live attenuated
Severe
How does the drug interact with Atoxim-S 1.5 gm Injection:
Taking the cholera vaccine after or along with Atoxim-S 1.5 gm Injection may reduce the activity of the vaccine.

How to manage the interaction:
Taking Atoxim-S 1.5 gm Injection with Cholera, live attenuated together can possibly result in an interaction, but it can be taken if your doctor has advised it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual symptoms, consult a doctor. Do not discontinue any medications without first consulting your doctor.
CeftizoximeCholera vaccines
Severe
How does the drug interact with Atoxim-S 1.5 gm Injection:
Taking the cholera vaccine after or along with Atoxim-S 1.5 gm Injection may reduce the activity of the vaccine.

How to manage the interaction:
Co-administration of Atoxim-S 1.5 gm Injection with Cholera vaccines can possibly result in an interaction, but it can be taken if your doctor has advised it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid intake of alcoholic beverages with Atoxim-S 1.5 gm Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid Atoxim-S 1.5 gm Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Atoxim-S 1.5 gm Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Not applicable

Avoid consuming alcohol while taking Atoxim-S 1.5 gm Injection.

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Pregnancy

Caution

Atoxim-S 1.5 gm Injection should only be given during pregnancy when the need has been established. Therefore, please inform your doctor if you are pregnant or planning for pregnancy; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Inform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.

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Driving

Safe if prescribed

Atoxim-S 1.5 gm Injection is unlikely to affect your ability to drive.

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Liver

Caution

Caution should be exercised while using Atoxim-S 1.5 gm Injection in patients with liver disease. Inform your doctor before receiving Atoxim-S 1.5 gm Injection if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Caution should be exercised while using Atoxim-S 1.5 gm Injection in patients with kidney disease. Inform your doctor before receiving Atoxim-S 1.5 gm Injection if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Limited information is available for the use of Atoxim-S 1.5 gm Injection in children. Hence, it will be administered to the children only if needed.

Have a query?

FAQs

Atoxim-S 1.5 gm Injection is used to treat Bacterial infections.

Atoxim-S 1.5 gm Injection contains Ceftizoxime and Sulbactam. Ceftizoxime works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby killing the bacteria. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Atoxim-S 1.5 gm Injection helps to treat bacterial infections.

Atoxim-S 1.5 gm Injection may cause Clostridium difficile-associated diarrhoea (CDAD). Antibiotic treatment alters the normal flora, leading to overgrowth of Clostridium difficile, which causes diarrhoea. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Atoxim-S 1.5 gm Injection and consult your doctor. Do not take anti-diarrheal medicine on your own.

Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor.

Usually, Atoxim-S 1.5 gm Injection starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.

To reduce the development of antibiotic resistance and maintain the effectiveness of Atoxim-S 1.5 gm Injection, it should only be used to treat or prevent infections that are proven or highly suspected to be caused by bacteria.

Country of origin

India

Manufacturer/Marketer address

B-20, 2Nd Floor, Ii Phase, Okhla Industrial Estate, New Delhi, Delhi 110020
Other Info - ATO0634

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:19 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/drug-interactions/ceftizoxime.html
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3574df06-fec5-4888-8080-3b817addfb02&amp;type=display
  3. https://www.drugs.com/mtm/ceftizoxime.html
  4. https://drugs.ncats.io/drug/26337D5X88
  5. https://ciplamed-library.com/content/sulbacip-iv-injection
  6. https://www.mims.com/thailand/drug/info/sibatam?type=full
  7. https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/Ceftriaxone%20and%20%20sulbactam.pdf%20injection#:~:text=Store%20below%2030%C2%BAC%20in%20a,Protect%20from%20light.

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