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compositionComposition:ARTEMETHER-80MG+LUMEFANTRINE-480MG
prescription
Prescription Medicine
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Artedol 80mg/480mg Tablet is used to treat and prevent malaria. It contains Artemether and Lumefantrine, which interfere with the Plasmodium parasite's growth in the red blood cells of the human body. It is a combination medicine used to treat non-severe malaria caused by a parasite called Plasmodium falciparum. It may cause common side effects, such as headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle or joint pain, nausea, vomiting, abdominal pain, cough, and trouble sleeping. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ARTEMETHER-80MG+LUMEFANTRINE-480MG

Manufacturer/Marketer :

Silicon Pharma

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Artedol 80mg/480mg Tablet

Artedol 80mg/480mg Tablet is a prescription oral medication used to treat acute, uncomplicated malaria infections caused by parasites. This medicine is designed to clear the malaria parasite from your body, helping you recover from the infection. It is formulated specifically for oral intake and is highly effective when used correctly under medical supervision.

It is crucial to take Artedol 80mg/480mg Tablet exactly as your doctor instructs and complete the full course of treatment, even if you start feeling better within a few hours. This medicine must always be taken with food, preferably a meal rich in fat (such as milk, cheese, or food cooked with oil), because fat significantly helps your body absorb the active medicine. Additionally, drinking plenty of clean fluids and getting plenty of physical rest are simple lifestyle steps that will support your body's recovery during treatment.

While taking Artedol 80mg/480mg Tablet, you may experience common, mild side effects such as headaches, dizziness, or a temporary loss of appetite. However, you should contact your doctor immediately if you experience serious symptoms like a fast or irregular heartbeat, severe dizziness, or signs of liver damage, which include yellowing of your eyes or skin and dark urine.

Do not take this medicine if you have a history of severe heart rhythm abnormalities, a family history of sudden heart issues, or low levels of potassium or magnesium in your blood. Before starting treatment, talk to your doctor if you have liver damage, kidney disease, or any pre-existing heart conditions to ensure this medication is safe for you.

This medication can interact with other drugs, especially those that affect your heart rhythm, so it is important to share your full medication list with your healthcare provider. Avoid drinking alcohol during treatment, as it can worsen dizziness and put extra strain on your liver. If you are pregnant, breastfeeding, or an older adult, you must consult your doctor before taking this medicine.

Uses of Artedol 80mg/480mg Tablet

Artedol 80mg/480mg Tablet is used in the treatment of malaria. The detailed uses of Artedol 80mg/480mg Tablet are as follows:

  • Acute uncomplicated malaria: Artedol 80mg/480mg Tablet is prescribed to treat active, non-severe malaria infections caused by the Plasmodium falciparum parasite in adults, children, and infants weighing at least 5 kg.
  • Chloroquine-resistant malaria: This medicine is highly effective for treating malaria cases in which the parasite has developed resistance to older standard malaria treatments.

Key Benefits

Artedol 80mg/480mg Tablet helps treat uncomplicated malaria, allowing you to recover more quickly from the infection.

Benefits may include:

  • Works quickly to clear malaria parasites from your bloodstream.
  • Helps reduce high fever, chills, body aches, and severe fatigue, with many patients starting to feel better within 24 to 48 hours of beginning treatment.
  • Combines two active ingredients that work together to effectively eliminate malaria parasites.
  • Helps prevent the infection from progressing to severe, life-threatening malaria when taken as prescribed.
  • Treatment is typically completed over just three days, making it simpler than many older malaria regimens.
  • The short treatment duration helps improve treatment completion and increases the likelihood of a successful recovery.
Side effects of Artedol 80mg/480mg Tablet
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
  • Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
  • Exercise regularly to maintain a good metabolism in your body.
  • Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
  • Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Incorporate foods high in antioxidants, such as tomatoes, leafy greens, and berries, to prevent inflammation.
  • Encourage stress-relieving activities like yoga, deep breathing, and meditation.
  • Support the immune system and help the body rid itself of toxins.
  • Regularly check white blood cell counts to monitor the effectiveness of therapy and make any necessary modifications.

Directions for Use

  • Swallow the tablets whole with a glass of water. Do not crush or chew them unless instructed by your doctor.
  • For young children who cannot swallow tablets, the tablet may be crushed and mixed with a small amount of water or condensed milk immediately before taking.
  • Take each dose with food, milk, or a high-fat meal to ensure the medication is properly absorbed by your body.
  • If you vomit within one hour of taking your dose, you must take another dose immediately and contact your doctor.
  • Always follow your doctor's exact instructions regarding the timing and duration of your treatment.

How Artedol 80mg/480mg Tablet Works

Artedol 80mg/480mg Tablet is a combination medicine containing two active ingredients that work together to kill the malaria parasite at different stages of its life cycle. • Artemether: It starts working rapidly after absorption. Inside the malaria parasite, it generates highly reactive free radicals (reactive oxygen species) that damage essential parasite proteins and membranes, rapidly killing most of the parasites. • Lumefantrine: It works more slowly but remains in your body for much longer. It interferes with the parasite's ability to detoxify toxic heme produced during haemoglobin digestion by inhibiting heme polymerisation, helping eliminate any remaining parasites and reducing the risk of the infection returning.
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Alcohol

Unsafe

Avoid alcohol while using Artedol 80mg/480mg Tablet since it can worsen your side effects.

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Pregnancy

Unsafe

Artedol 80mg/480mg Tablet is not recommended during the first three months of pregnancy. Your doctor may recommend other alternative medications. Please seek medical advice if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Artedol 80mg/480mg Tablet is not recommended during breastfeeding. Once you have completed the course, you should wait at least one week before starting to breastfeed again. Please consult your doctor before taking Artedol 80mg/480mg Tablet.

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Driving

Unsafe

Artedol 80mg/480mg Tablet may cause you to feel sleepy, dizzy, or generally weak. In such cases, do not drive or operate machinery.

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Liver

Caution

Close monitoring of patients with liver disease while they are treated with Artedol 80mg/480mg Tablet is required. Let your doctor know if you have any history of liver disease before using Artedol 80mg/480mg Tablet.

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Kidney

Caution

Therapy with Artedol 80mg/480mg Tablet is to be cautiously administered in patients with renal impairment. Let your doctor know if you have any history of kidney disease before using Artedol 80mg/480mg Tablet.

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Children

Caution

Your doctor will decide the dose based on your child's age and body weight.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Artedol 80mg/480mg Tablet can be given in elderly patients with caution and only if prescribed by the doctor.

What if I have taken an overdose of Artedol 80mg/480mg Tablet

If you take more than your prescribed dose, or if you suspect an overdose, seek immediate emergency medical attention or contact a poison control centre. Overdose symptoms may include severe heart palpitations, extreme dizziness, or fainting.

Diet & Lifestyle Advise

  • Eat fat-rich foods: Always take each dose with foods high in fat, such as whole milk, cheese, yoghurt, eggs, or meals prepared with butter or oil, to ensure your body absorbs the medication effectively.
  • Stay hydrated: Drink plenty of clean water, broth, or oral rehydration solutions to replace fluids lost due to high fevers, sweating, or vomiting.
  • Prioritise rest: Give your body plenty of physical rest to help your immune system fight off the infection and recover your strength.
  • Eat small, frequent meals: If you suffer from a loss of appetite or nausea, try eating small, nutrient-dense snacks throughout the day instead of large meals.
health query

Have a query?

How Soon It Starts Working

  • The time required for Artedol 80mg/480mg Tablet to start to work: The time required for Artedol 80mg/480mg Tablet to show its action is unknown.
  • The time for which the effects of Artedol 80mg/480mg Tablet last: The duration of action for Artedol 80mg/480mg Tablet is unknown.

What if you forget to take Artedol 80mg/480mg Tablet

If you miss a dose, take it as soon as you remember, making sure to take it with a fat-rich meal or drink. However, if your next scheduled dose is only a few hours away, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Complete the full course: Take every dose exactly as prescribed, even if you start feeling better after the first day. Stopping treatment too soon may allow the infection to return.
  • Check the packaging: Inspect the blister pack before taking your medicine. Do not use it if the foil is torn, punctured, or damaged.
  • Use only for treatment: Take this medicine only to treat a confirmed malaria infection. Do not use it to prevent malaria unless your doctor specifically advises you to do so.
  • Be careful when driving: Avoid driving, riding a bicycle, or operating heavy machinery until you know how this medicine affects you, as it may cause dizziness in some patients.
  • Watch for heart symptoms: Contact your doctor immediately if you notice a fast or irregular heartbeat, a fluttering feeling in your chest, or feel faint or lightheaded during treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Heart rhythm medications (e.g., amiodarone, quinidine): Taking these medicines alongside Artedol 80mg/480mg Tablet may increase the risk of serious irregular heartbeats and may require closer monitoring.
  • Antipsychotic or Antidepressant Medicines (e.g., haloperidol, citalopram): Taking these medicines alongside Artedol 80mg/480mg Tablet may increase the risk of abnormal heart rhythms.
  • Other antimalarial drugs (e.g., quinine, mefloquine): Taking Artedol 80mg/480mg Tablet alongside certain other antimalarial medicines may increase the risk of heart rhythm problems (QT prolongation) and other side effects. Only combine antimalarial treatments if specifically instructed by your doctor.
ArtesunateCabozantinib
Severe
ArtesunateEluxadoline
Severe

Drug-Drug Interactions

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ArtesunateCabozantinib
Severe
How does the drug interact with Artedol 80mg/480mg Tablet:
Taking Artedol 80mg/480mg Tablet with Cabozantinib may increase blood levels and effects of Artedol 80mg/480mg Tablet and increase the risk of side effects.

How to manage the interaction:
Although taking Artedol 80mg/480mg Tablet with cabozantinib together can result in an interaction, they can be taken if a doctor has prescribed it. Do not discontinue any medication without consulting a doctor.
ArtesunateEluxadoline
Severe
How does the drug interact with Artedol 80mg/480mg Tablet:
Taking Artedol 80mg/480mg Tablet with Eluxadoline may significantly increase the blood levels of eluxadoline. This may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Artedol 80mg/480mg Tablet and Eluxadoline, you can take these medicines together if prescribed by a doctor. However, if you experience persistent nausea, vomiting, drowsiness, constipation, stomach tenderness, and upper stomach pain, especially that which worsens after eating or radiates to the back or shoulders, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Drinking grapefruit juice while taking this medicine may increase the amount of the drug in your body, raising the risk of severe side effects.
  • Low-fat meals: Taking this medicine on an empty stomach or with a completely fat-free meal will drastically reduce its absorption, making the treatment ineffective.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- MALARIALS]

FAQs

Artedol 80mg/480mg Tablet belongs to the class of anti-malarial drugs, used to treat and prevent malaria.
Artedol 80mg/480mg Tablet contains a combination of anti-malarial drugs, Artemether and Lumefantrine. It treats malaria by interfering with Plasmodium parasite's growth in the red blood cells of the human body.
Artedol 80mg/480mg Tablet may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.
Artedol 80mg/480mg Tablet is not recommended in cases of any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases and electrolyte imbalance. Also, let your doctor know if you have recently undergone treatment with other anti-malarial drugs.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Artedol 80mg/480mg Tablet should be swallowed as a whole with water; do not crush or chew it.
Artedol 80mg/480mg Tablet is not recommended during the first three months of pregnancy. Your doctor may recommend other alternative medications. Please seek medical advice if you are pregnant or planning to conceive.
Artedol 80mg/480mg Tablet is contraindicated if you are allergic to any of its components.
Store Artedol 80mg/480mg Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.
Artedol 80mg/480mg Tablet should be taken with food as it aids in better absorption of the medicine.
Take another dose of Artedol 80mg/480mg Tablet if you have vomited within 1-2 hours of taking the medicine.
Artedol 80mg/480mg Tablet may cause side effects such as headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle or joint pain, nausea, vomiting, abdominal pain, cough, and trouble sleeping. These side effects are not familiar to everyone and vary from person to person. If you notice any side effects that are not manageable, please consult your doctor.
Do not discontinue Artedol 80mg/480mg Tablet without consulting your doctor. To treat your condition effectively, keep taking Artedol 80mg/480mg Tablet for the prescribed duration.
No, Artedol 80mg/480mg Tablet is not approved for malaria prevention. It is exclusively used to treat active, confirmed malaria infections. Your doctor can recommend a suitable medicine to help prevent malaria before you travel.
Fatty foods, such as milk, eggs, or cheese, act as a carrier that helps your digestive system absorb the active ingredients in Artedol 80mg/480mg Tablet. Without fat, the medicine will not enter your bloodstream in sufficient amounts to clear the infection. Your doctor or pharmacist can also suggest suitable foods or drinks to take with each dose.
Yes, Artedol 80mg/480mg Tablet can be used in children and infants weighing at least 5 kg, but the dosage must be carefully calculated based on the child's body weight. It is not recommended for infants weighing less than 5 kg because its safety and effectiveness have not been adequately established. Your child's healthcare provider will determine the correct dose based on body weight.
It is highly advised to avoid alcohol while taking Artedol 80mg/480mg Tablet. Alcohol can worsen common side effects like dizziness and headaches, and it can also place unnecessary stress on your liver. If you are unsure whether alcohol is safe for you, ask your healthcare provider for advice.

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Country of origin

India

Manufacturer/Marketer address

Shop No. 6, 2nd Floor, Om Shanti Co- Op. Hsg. Soc. 42/44, Babu Genu Road, Kalbadevi Mumbai Mh 400002 In
Other Info - AR35118
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