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compositionComposition:DONEPEZIL-5MG+MEMANTINE-10MG
prescription
Prescription Medicine
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Arizex Forte Tablet is used to treat Alzheimer's disease (memory loss). It contains Donepezil and Memantine, which balance the levels of chemical messengers in the brain and help transmit nerve signals. It may cause side effects such as vomiting, weight loss, loss of appetite, dryness in the mouth, dizziness, nausea, diarrhoea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DONEPEZIL-5MG+MEMANTINE-10MG

Manufacturer/Marketer :

Consern Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Arizex Forte Tablet

Arizex Forte Tablet is an oral prescription medication used to treat moderate to severe dementia associated with Alzheimer's disease. It helps manage symptoms affecting memory, awareness, and the ability to perform daily activities by supporting communication between brain cells. While it is not a cure, it works to slow down the progression of these cognitive symptoms.

For the best results, you must take Arizex Forte Tablet consistently every day, exactly as your doctor prescribes. You can take this medication with or without food, but taking it at the same time each day helps keep a stable level of the medicine in your body. Incorporating a structured daily routine, balanced nutrition, and gentle mental exercises can also help support the treatment's outcomes.

While taking Arizex Forte Tablet , some people may experience mild side effects like nausea, diarrhoea, or temporary dizziness. However, you must watch for more serious signs and consult your doctor immediately if you or the patient experiences an unusually slow heart rate, fainting, or severe stomach pain.

Before starting Arizex Forte Tablet , talk to your doctor if you have a history of heart rhythm problems, asthma, chronic lung disease, seizures, or stomach ulcers. Do not take this if you have a known allergy to any of the active ingredients in this medication.

Certain medications, particularly some pain relievers or other muscle relaxants, can interact with Arizex Forte Tablet , so tell your healthcare provider about everything you take. Avoid drinking alcohol while using this medicine, as it can significantly worsen dizziness and confusion. Always consult your doctor if you are caring for an elderly patient, or if the patient is pregnant or breastfeeding.

Uses of Arizex Forte Tablet

Arizex Forte Tablet is used in the treatment of Alzheimer’s disease. The detailed uses of Arizex Forte Tablet are as follows:

  • Moderate to severe Alzheimer's disease: Arizex Forte Tablet is used to improve or maintain cognitive functions, such as thinking, memory, communication, and the ability to perform daily tasks in patients with advanced dementia.

Key Benefits

Arizex Forte Tablet helps support daily functioning and cognitive health, making it easier for patients to maintain their independence for a longer period. By stabilising mood and improving memory, it greatly enhances the overall quality of life for both the patient and their caregivers.

Benefits may include:

  • Makes it easier for patients to continue managing everyday tasks, such as eating, bathing, and dressing.
  • Enhances cognitive functions, allowing patients to engage more actively in conversations and social interactions.
  • Effectively reduces distressing behavioural symptoms like confusion, agitation, and anxiety.
  • By improving the patient's daily functioning and creating a calmer environment, it significantly eases the daily emotional and physical strain on caregivers.

Directions for Use

  • Take Arizex Forte Tablet with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Arizex Forte Tablet Works

Arizex Forte Tablet combines two active medicines, Donepezil and Memantine, that work in different but complementary ways in the brain to support cognitive function. • Donepezil: It is a cholinesterase inhibitor. It works by preventing the breakdown of a natural chemical messenger in the brain called acetylcholine. This messenger is vital for memory, learning, and overall thinking. By keeping acetylcholine levels higher, it helps brain cells communicate more effectively with one another. • Memantine: Memantine is an NMDA receptor antagonist. It works by regulating the activity of glutamate, another key chemical messenger in the brain. In Alzheimer's disease, damaged brain cells release too much glutamate, which can overstimulate and further damage healthy cells. By balancing glutamate activity, this medicine protects brain cells from harmful overstimulation and helps clear brain signals.
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Alcohol

Caution

Taking alcohol, along with Arizex Forte Tablet , may increase its drowsiness effect and cause excessive sleepiness.

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Pregnancy

Caution

Arizex Forte Tablet is a pregnancy category C drug. It is not known whether it will harm the baby. So, take only if prescribed by a doctor.

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Breast Feeding

Caution

It is not known whether Arizex Forte Tablet passes through breast milk or not. So, caution should be exercised if you are breastfeeding.

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Driving

Unsafe

Arizex Forte Tablet is known to cause drowsiness, so please do not drive a car or operate any machinery which requires mental alertness.

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Liver

Caution

Arizex Forte Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Arizex Forte Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Caution

The safety and efficacy of Arizex Forte Tablet in children have not been established.

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Heart

Caution

Arizex Forte Tablet should be taken with extreme caution in patients with heart disease. Please consult your physician.

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Geriatrics

Safe if prescribed

Arizex Forte Tablet can be safely given in elderly patients if recommended by the physician.

What if I have taken an overdose of Arizex Forte Tablet

If you suspect an overdose, seek immediate emergency medical attention. Symptoms of an overdose may include severe nausea, vomiting, drooling, heavy sweating, a very slow heart rate, shallow breathing, or fainting.

Diet & Lifestyle Advise

  • Provide a brain-healthy diet: Serve meals rich in antioxidants, leafy green vegetables, berries, whole grains, and healthy fats like olive oil and fish to support overall physical and brain health.
  • Prioritise hydration: Encourage the patient to drink water regularly throughout the day, as even mild dehydration can worsen confusion and cognitive symptoms.
  • Create a structured daily routine: Keeping consistent times for waking up, eating, and sleeping helps reduce confusion, anxiety, and agitation in patients with dementia.
  • Encourage physical activity: Simple, supervised physical activities like short daily walks can help maintain mobility, improve sleep quality, and boost mood.
  • Engage in gentle brain exercises: Activities like listening to familiar music, looking through photo albums, or doing simple puzzles can help keep the mind active and engaged.
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How Soon It Starts Working

  • The time required for Arizex Forte Tablet to start to work: The time required for Arizex Forte Tablet to show its action is not clinically established.
  • The time for which the effects of Arizex Forte Tablet last: The duration of action for Arizex Forte Tablet is clinically established.

What if you forget to take Arizex Forte Tablet

If you miss a dose of Arizex Forte Tablet , skip the missed dose and take your next scheduled dose at your normal time. Do not take two doses at once to make up for a missed one. If you miss taking this medication for several days in a row, talk to your doctor or pharmacist before starting to take it again.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor heart rhythm: Monitor the patient's heart rate regularly, especially if they have a history of heart conditions, as this medication can cause a slow heart rate.
  • Coordinate medical procedures: If the patient is scheduled for any surgery or dental procedure, inform the surgeon or dentist that they take Arizex Forte Tablet , as it can interact with certain muscle relaxants used during anaesthesia.
  • Watch for stomach irritation: Look closely for signs of stomach irritation or bleeding, especially if the patient regularly takes pain relievers like ibuprofen or naproxen.
  • Limit hazardous activities: Do not let the patient drive or operate machinery if they experience dizziness, confusion, or sleepiness while taking this medicine.
  • Avoid stopping abruptly: Never stop giving this medication without consulting your healthcare provider first, as stopping suddenly can cause cognitive symptoms to worsen quickly.

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Drug-Drug Interaction:

  • NSAIDs (like ibuprofen or naproxen): May increase the risk of developing stomach ulcers and stomach bleeding when taken alongside Arizex Forte Tablet .
  • Anticholinergic drugs (like certain allergy, bladder control, or cold medicines): May block the action of Arizex Forte Tablet , making both medicines less effective.
  • Anaesthetics: Can interact with Arizex Forte Tablet , potentially prolonging the effects of muscle relaxants used during surgical procedures.
  • Other cholinesterase inhibitors: Combining Arizex Forte Tablet with similar medicines can increase the risk of side effects like severe nausea, vomiting, or a slow heart rate.

Drug-Food Interaction:

  • There are no major established drug-food interactions with Arizex Forte Tablet . It can be taken safely with or without food.

Drug-Disease Interaction:

  • Heart conditions (like sick sinus syndrome): May increase the risk of a dangerously slow heart rate or fainting.
  • Stomach ulcers or bleeding history: May increase the risk of developing new stomach irritation or bleeding.
  • Asthma or COPD: Can worsen breathing difficulties or trigger airway tightening.
  • Seizures: May increase the susceptibility to experiencing a seizure.
  • Urinary tract obstruction: Can make passing urine more difficult.

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Habit Forming

No

Therapeutic Class

[CENTRAL NERVOUS SYSTEM AGENTS]

FAQs

Arizex Forte Tablet is used to treat Alzheimer's disease (memory loss), a progressive neurodegenerative disorder that affects the brain.
Arizex Forte Tablet is a combination medication containing Donepezil and Memantine, which treat Alzheimer's disease. Donepezil works by improving the function of nerve cells in the brain by preventing the breakdown of the chemical acetylcholine. Memantine works by lowering the level of chemicals in the brain which is responsible for causing symptoms of Alzheimer's disease. Together, they balance the levels of chemical messengers in the brain and help transmit nerve signals.
No, it is recommended not to take Arizex Forte Tablet before surgery as it contains Donepezil, which is a cholinesterase inhibitor and is likely to exaggerate muscle relaxation during anaesthesia. So, please inform your doctor before surgery if you are taking Arizex Forte Tablet , as he might stop it 2 hours before undergoing surgery.
Yes, the use of Arizex Forte Tablet can cause diarrhoea. In some cases, the patient may experience diarrhoea. So, please increase the intake of fluids to avoid dehydration. And also do not take any other medicines without speaking to a doctor.
Yes, Arizex Forte Tablet is known to cause weight loss. So, while taking Arizex Forte Tablet , you should constantly monitor your body weight to avoid major weight loss.
Taking Arizex Forte Tablet in more than the recommended dose can cause unpleasant side effects such as dizziness, tremor, agitation, convulsion, coma, nausea, vomiting, changes in heart rhythm, decreased blood pressure, and changes in body fluid/salt balance.
Yes, Alzheimer's disease (memory loss) generally occurs in people who are elderly and aged. So, Arizex Forte Tablet is safe for the elderly population, but the dose should be given by a doctor depending upon any underlying disease condition you are suffering from. Also, never self-medicate.
Arizex Forte Tablet may cause side effects like vomiting, weight loss, loss of appetite, dryness in the mouth, dizziness, nausea, diarrhoea, and headache. Most of these side effects of Arizex Forte Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Alzheimer's disease is a progressive neurodegenerative disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells to die. One of the very common causes of Alzheimer's disease is dementia (memory loss), which affects the person's ability to function independently.
Take Arizex Forte Tablet preferably just before bedtime or as advised by the doctor.
Arizex Forte Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Arizex Forte Tablet can be taken along with my other regular medicines if advised by the doctor. Please consult the doctor before taking other medicines with Arizex Forte Tablet to prevent any interactions/side effects.
Do not discontinue Arizex Forte Tablet without consulting your doctor. To treat your condition effectively, keep taking Arizex Forte Tablet for the prescribed duration.
Store Arizex Forte Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Arizex Forte Tablet is contraindicated if you are allergic to any of its components.
Inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma.
Taking more than the recommended dose of Arizex Forte Tablet may cause an overdose. The symptoms of overdose include slow heart rate, severe dizziness, drowsiness, vomiting, sweating, weakness, trouble walking, agitation, confusion, unusual thoughts or behaviour, hallucinations, fainting, fits, and shallow or weak breathing. If you suspect the patient has taken an overdose or notice signs of overdose, please consult a doctor immediately.
No, Arizex Forte Tablet does not cure Alzheimer's disease. Instead, it is designed to manage the symptoms of moderate to severe dementia by helping improve memory, awareness, and daily function. Talk to your doctor to understand what to expect during treatment.
Arizex Forte Tablet is typically taken once a day, often in the evening or at bedtime. However, you should always follow the specific dosing schedule recommended by your healthcare provider. Talk to your doctor if you have questions about the timing.
No, you should swallow the tablet whole with water. Crushing, chewing, or breaking the tablet can alter how the medicine is absorbed, which can increase the risk of side effects. Talk to your doctor or pharmacist if swallowing tablets is difficult.
Dizziness can occur, especially when first starting the medicine or during a gradually increasing dose. Ensure the patient stands up slowly and avoids sudden movements. If the dizziness is severe, causes fainting, or does not improve, talk to your doctor immediately.
No, it is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase side effects like confusion, dizziness, and drowsiness, making dementia symptoms harder to manage. Talk to your doctor if you have concerns.
Yes, Arizex Forte Tablet can sometimes cause a slow heart rate (bradycardia) or fainting, particularly in patients who already have heart conditions. If you notice a very slow pulse, dizziness, or lightheadedness, seek medical help right away and talk to your doctor.
If several daily doses are missed, do not double the next dose to catch up. Contact your doctor before restarting the medicine, as they may advise resuming treatment at a lower dose to avoid side effects. Talk to your doctor for specific guidance.

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Country of origin

India

Manufacturer/Marketer address

Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India.
Other Info - ARI0220

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