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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Arifine 10 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.

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Whats That

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Composition :

ARIPIPRAZOLE-10MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arifine 10 Tablet

 Arifine 10 Tablet is an antipsychotic medicine used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Arifine 10 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterised by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused by disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Arifine 10 Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Arifine 10 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet improves mood swings, depression, and other psychotic problems. 

Take Arifine 10 Tablet as prescribed. Your doctor will advise you on how often to take Arifine 10 Tablet , based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 10 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Arifine 10 Tablet or any other medicines, please tell your doctor. Arifine 10 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions, including dizziness, difficulty moving and maintaining balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Arifine 10 Tablet if you are pregnant or breastfeeding, and consult a doctor. Arifine 10 Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Arifine 10 Tablet , please get in touch with a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 10 Tablet .

Uses of Arifine 10 Tablet

Arifine 10 Tablet is primarily used in the treatment of schizophrenia. Its specific uses are as follows:<br/> • Schizophrenia: Arifine 10 Tablet is used to treat schizophrenia in adults and children aged 13 years and older. It helps manage negative symptoms of schizophrenia, such as lack of emotion, social isolation, poor attention, and memory loss.<br/> • Bipolar I Disorder (Manic Depression): Arifine 10 Tablet is used alone or in combination with mood stabilizers (like valproate or lithium) to treat acute episodes of mania (abnormally elevated mood) in adults and children aged 10 years and older. It helps stabilize mood and reduce irritability and hyperactivity.<br/> • Major Depressive Disorder (MDD) - As Adjunctive Therapy: Arifine 10 Tablet is used in combination with antidepressants to treat MDD when antidepressants alone are not effective. It helps improve mood, energy levels, and overall functioning.<br/> • Tourette Syndrome (TS): Arifine 10 Tablet is used to reduce the severity and frequency of tics (sudden, uncontrollable vocal sounds or movements) in children over 6 years with TS.<br/> • Autism Spectrum Disorder (ASD): Arifine 10 Tablet is used to manage the symptoms of ASD in children over 6 years, such as mood swings, irritability, aggression, tantrums, and self-injurious behaviour.<br/> • Maintenance Treatment: Arifine 10 Tablet is used for long-term management of schizophrenia and bipolar disorder to prevent relapse or worsening of symptoms.<br/>

Directions for Use

  • Arifine 10 Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Arifine 10 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Arifine 10 Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Arifine 10 Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet improves overall behaviour and thoughts, helping people lead a better social life and comfortably perform daily activities. Arifine 10 Tablet may be used in combination with other medicines to treat depression. Additionally, Arifine 10 Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

How Arifine 10 Tablet Works

Arifine 10 Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Arifine 10 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet improves mood swings, depression, and other psychotic problems.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Arifine 10 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Do pelvic floor exercises (Kegel exercises) to gain more control over urinary sphincters (muscles used to control flow of urine out of the bladder).
  • Drink fluids only at certain times to control when you will urinate.
  • If you feel frequent urge to urinate or have problems starting to urinate or if your urine stream is weak or starts and stops, or feel pain in your genitals, lower abdomen or lower back, consult your doctor.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Arifine 10 Tablet

Do not take more than the prescribed dose of Arifine 10 Tablet , as it may cause an overdose. Symptoms of an overdose may include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Arifine 10 Tablet or any other medicines, please tell your doctor. Arifine 10 Tablet should be used with caution in elderly patients above 65 years of age, as there is an increased risk of adverse reactions, including dizziness, changes in mobility and balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Arifine 10 Tablet if you are pregnant or breastfeeding, and consult a doctor. Arifine 10 Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Arifine 10 Tablet , please get in touch with a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or you are advised to stop taking Arifine 10 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 10 Tablet .

Drug-Drug Interactions

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BaclofenMethadone
Severe

Drug-Drug Interactions

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BaclofenMethadone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Methadone may cause serious side effects such as central nervous system depression can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Methadone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Buprenorphine with Arifine 10 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Buprenorphine alongside Arifine 10 Tablet can result in an interaction. However, it can be taken if a doctor has advised it. If you experience shortness of breath, chest discomfort, dizziness, or palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Tapentadol together with Arifine 10 Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Arifine 10 Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
BaclofenDezocine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Dezocine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Dezocine if prescribed by the doctor. These may cause dizziness, drowsiness, palpitations, or chest discomfort. Do not stop taking the medications without a doctor's advice.
BaclofenHydrocodone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.
BaclofenPotassium hydrogencarbonate
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet may decrease the excretion rate of Potassium hydrogencarbonate which could result in a higher serum level.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Potassium hydrogencarbonate if prescribed by the doctor. Regular monitoring of serum potassium levels is advised.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Butorphanol can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Arifine 10 Tablet and Butorphanol, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like dizziness, shortness of breath, palpitations, or chest discomfort, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
BaclofenCodeine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Codeine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Codeine if prescribed by the doctor. These medications may cause dizziness, drowsiness, shortness of breath, or palpitations, consult a doctor immediately. Do not stop any medication without a doctor's advice.
BaclofenEsketamine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Esketamine may increase the risk or severity of adverse effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Esketamine if prescribed by the doctor. Consult a doctor if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, and reaction speed. Do not stop any medication without doctor's consultation.
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet can enhance the sedative effects of Pentazocine on the central nervous system which can lead to side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Arifine 10 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Arifine 10 Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards, and herring.
  • Cut down sugars, salt, and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Engage in regular exercise and maintain a stable weight, as Arifine 10 Tablet may contribute to weight gain.
  • Avoid alcohol consumption, as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid alcohol consumption while taking Arifine 10 Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

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Pregnancy

Unsafe

Arifine 10 Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Arifine 10 Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Arifine 10 Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Arifine 10 Tablet .

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Liver

Caution

Take Arifine 10 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Arifine 10 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Arifine 10 Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Arifine 10 Tablet to children.

Have a query?

FAQs

Arifine 10 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.

Arifine 10 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Arifine 10 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Arifine 10 Tablet improves behaviour, thoughts, and helps in having a better social life, enabling one to comfortably perform daily activities.

No, you are not recommended to take Arifine 10 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Arifine 10 Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Arifine 10 Tablet with other medicines.

Arifine 10 Tablet may cause weight gain in some patients, but it is not a necessary side effect for everyone taking Arifine 10 Tablet . However, to avoid gaining weight while taking Arifine 10 Tablet , it is advisable to engage in regular exercise and limit high-calorie drinks. Instead, opt for non-alcoholic beverages, herbal tea, and lemon water.

Arifine 10 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Arifine 10 Tablet .

Yes, Arifine 10 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Arifine 10 Tablet and inform your doctor if you have diabetes before taking Arifine 10 Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.

No, you are not recommended to stop taking Arifine 10 Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Arifine 10 Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Arifine 10 Tablet , please consult your doctor so that the dose can be gradually reduced.

Yes, Arifine 10 Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.

Arifine 10 Tablet might start working within a few days or weeks. However, you may notice the full benefits of Arifine 10 Tablet after 2-3 months. Continue taking Arifine 10 Tablet for the prescribed duration to prevent the recurrence of symptoms.

Arifine 10 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.

Elderly patients more than 65 years old with dementia-related psychosis treated with Arifine 10 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Arifine 10 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.

Avoid intake of grapefruit juice with Arifine 10 Tablet as it may reduce the effect of Arifine 10 Tablet . Also, avoid alcohol consumption with Arifine 10 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Arifine 10 Tablet .

Consult the doctor if you are diabetic, as Arifine 10 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.

Arifine 10 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 10 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP
Other Info - ARI0160

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